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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Publication Detail

Title: Personal exposure to fine particulate matter and blood pressure: Variations by particulate sources.

Authors: Lei, Xiaoning; Chen, Renjie; Li, Weihua; Cheng, Zhen; Wang, Hongli; Chillrud, Steven; Yan, Beizhan; Ying, Zhekang; Cai, Jing; Kan, Haidong

Published In Chemosphere, (2021 Oct)

Abstract: Fine particulate matter (PM2.5) is a complex mixture of components which has been associated with various cardiovascular effects, such as elevated blood pressure (BP). However, evidences on specific sources behind these effects remain uncertain. Based on 140 72-h personal measurements among a panel of 36 health college students in Shanghai, China, we assessed associations between source-apportioned PM2.5 exposure and BP changes. Based on personal filter samples, PM2.5 source apportionment was conducted using Positive Matrix Factorization (PMF) model. Linear mixed-effects models were applied to evaluate associations of source-specific PM2.5 exposure with BP changes. Seven sources were identified in PMF analysis. Among them, secondary sulfate (41%) and nitrate (24%) sources contributed most to personal PM2.5, followed by industrial emissions (15%), traffic-related source (10%), coal combustion (6.2%), dust (2.4%) and aged sea salt (1.1%). We found nitrate, traffic-related source and coal combustion were significantly associated with increased BP. For example, an interquartile range increase in PM2.5 from traffic-related source was significantly associated with increase in systolic BP [1.5 (95% CI: 0.26, 2.7) mmHg], diastolic BP [1.2 (95% CI: 0.10, 2.2) mmHg] and mean arterial pressure [1.2 (95% CI: 0.15, 2.2) mmHg]. This is the first investigation linking personal PM2.5 source profile and BP changes. This study provides evidence that several anthropogenic emissions (especially traffic-related emission) may be particularly responsible for BP increases, and highlights that the importance of development of health-oriented PM2.5 source control strategies.

PubMed ID: 34162067 Exiting the NIEHS site

MeSH Terms: Aged; Air Pollutants*/analysis; Blood Pressure; China; Coal; Dust; Environmental Monitoring; Humans; Particulate Matter*/analysis; Vehicle Emissions/analysis

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