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Publication Detail

Title: Structural studies of natural product biosynthetic proteins.

Authors: Townsend, C A

Published In Chem Biol, (1997 Oct)

Abstract: The first high-resolution structures of key proteins involved in the biosynthesis of several natural product classes are now appearing. In some cases, they have resulted in a significantly improved mechanistic understanding of the often complex processes catalyzed by these enzymes, and they have also opened the way for more rational efforts to modify the products made.

PubMed ID: 9375250 Exiting the NIEHS site

MeSH Terms: Animals; Crystallography, X-Ray; Multienzyme Complexes/biosynthesis; Multienzyme Complexes/chemistry; Oxidoreductases/biosynthesis; Oxidoreductases/chemistry; Penicillins/biosynthesis; Protein Biosynthesis*; Proteins/chemistry*; Terpenes/chemistry; Terpenes/metabolism

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