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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Publication Detail

Title: Understanding the Placental Biology of Tobacco Smoke, Nicotine, and Marijuana (THC) Exposures During Pregnancy.

Authors: Banerjee, Sohini; Deacon, Alyssa; Suter, Melissa A; Aagaard, Kjersti M

Published In Clin Obstet Gynecol, (2022 Jun 01)

Abstract: Widespread public health campaigns have reduces the prevalence of tobacco and nicotine exposures during pregnancy in the United States. However, tobacco and nicotine exposures during pregnancy persist as a common modifiable perinatal risk exposure. Furthermore, declines in tobacco use have been accompanied by parallel rises in both the prevalence and incidence of marijuana use in pregnancy. This is worrisome, as the macromolecules which comprise tobacco and marijuana smoke affect placental function. In this chapter we summarize the decades of evidence contributing to our understanding of the placental molecular pathophysiology accompanying these chemical exposures, thereby rendering risk of adverse perinatal outcomes.

PubMed ID: 35125390 Exiting the NIEHS site

MeSH Terms: Biology; Cannabis*/adverse effects; Dronabinol/adverse effects; Female; Humans; Nicotiana; Nicotine/adverse effects; Placenta; Pregnancy; Smoke/adverse effects; Tobacco Smoke Pollution*/adverse effects

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