Title: Comparison of gene expression in cell culture to that in the intact animal: relevance to drugs and environmental toxicants. Focus on "development of a transactivator in hepatoma cells that allows expression of phase I, phase II, and chemical defense genes".
Authors: Nebert, Daniel W
Published In Am J Physiol Cell Physiol, (2006 Jan)
Abstract: Abstract not available from PubMed.
PubMed ID: 16338979
MeSH Terms: Animals; Carcinoma, Hepatocellular/genetics*; Cell Line, Tumor; Cells, Cultured; Gene Expression Regulation, Neoplastic/drug effects; Gene Expression Regulation, Neoplastic/physiology*; Hazardous Substances*; Humans; Liver Neoplasms/genetics*; Liver/cytology; Liver/physiology*; Models, Animal; Xenobiotics*