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Publication Detail

Title: The critical role of nucleus accumbens dopamine systems in the mediation of fixed interval schedule-controlled operant behavior.

Authors: Cory-Slechta, D A; Pazmino, R; Bare, C

Published In Brain Res, (1997 Aug 01)

Abstract: Microinjections of the irreversible dopamine antagonist EEDQ (N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline), into nucleus accumbens but not into dorsal striatum, markedly decreased response rates on a fixed interval schedule of reinforcement. These preferential effects in nucleus accumbens could be prevented by selectively activating either D1 or D2 receptors. These data demonstrate a critical role for mesolimbic dopamine systems in the mediation of fixed interval schedule-controlled operant behavior.

PubMed ID: 9295219 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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