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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Publication Detail

Title: In vivo exposure of human lymphocytes to technetium-99m in nuclear medicine patients does not induce detectable genetic effects.

Authors: Kelsey, K T; Donohoe, K J; Memisoglu, A; Baxter, B; Caggana, M; Liber, H L

Published In Mutat Res, (1991 Dec)

Abstract: Recent reports have demonstrated that exposure of nuclear medicine patients to thallium-201 does not result in a detectable increase in mutation at the hprt locus in human lymphocytes. In an effort to study further the potential genetic effects of medical exposures to low dose radiation, we have examined chromosome aberrations and mutations in peripheral blood lymphocytes from nuclear medicine patients exposed to clinical doses of technetium-99m. Our results show that there is no exposure-related increase in chromosomal damage; furthermore, the data do not confirm earlier reports of exposure-related increases in mutations induced by technetium-99m.

PubMed ID: 1723502 Exiting the NIEHS site

MeSH Terms: No MeSH terms associated with this publication

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