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| Title | Principal Investigator | Institution | Grant Number | RFA PA Number | Program Officer | Pubs | Primary Science Code | Secondary Science Code |
|---|---|---|---|---|---|---|---|---|
| 2023-2025 ANNUAL MEETINGS OF THE ENVIRONMENTAL MUTAGENESIS AND GENOMICS SOCIETY (EMGS) | bemis, jeffrey c | Environmental Mutagenesis/Genomics Soc | R13ES036022 | PA21-151 | Shaughnessy, Daniel | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| ABERRANT DNA REPAIR AND LUPUS | sweasy, joann b. | University Of Nebraska Medical Center | R35ES031708 | ES19-007 | Heacock, Michelle | 10 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| ACCURATE AND COST-EFFECTIVE DETECTION OF MUTAGENICITY AND MUTAGENIC EXPOSURE | sharifi, sam | Mutagentech, Inc. | R43ES036101 | PA22-176 | Shaughnessy, Daniel | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| AN AUTOMATED DEVICE FOR QUANTIFYING DNA DAMAGE | ross, christopher | Engineering Resources Group, Inc. | R44ES030274 | PA23-232 | Shaughnessy, Daniel | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| APPLICATIONS OF THE LONG-TERM CULTURE HUMAN PRIMORDIAL GERM CELL-LIKE CELLS TO TOXICOLOGICAL ASSESSMENTS AND MECHANISTIC STUDIES ON CHEMICALLY CAUSED HERITABLE HUMAN HEALTH THREATS | shioda, toshihiro | Massachusetts General Hospital | R21ES034468 | PA20-195 | Shaughnessy, Daniel | 3 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| APPLYING GENOMIC DOSIMETERS OF UV DAMAGE TO PREDICTING SKIN CANCER RISK | brash, douglas e | Yale University | R01ES030562 | PAR18-704 | Shaughnessy, Daniel | 5 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| ATM ACTIVATION BY DNA SINGLE-STRAND BREAKS | yan, shan | University Of North Carolina Charlotte | R21ES032966 | PA20-195 | Heacock, Michelle | 10 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| CHEMICAL BIOLOGY OF DNA AND RNA ALKYLATION | wang, yinsheng | University Of California Riverside | R35ES031707 | ES19-007 | Tyson, Frederick | 43 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| COLLABORATIVE FUNCTIONS OF BRCA2 AND RAD51 PARALOGS IN HOMOLOGOUS RECOMBINATION | jensen, ryan brown | Yale University | R21ES034164 | PA20-195 | Shaughnessy, Daniel | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| CROSS-LINKS AT ABASIC SITES IN DUPLEX DNA | gates, kent s | University Of Missouri-Columbia | R01ES021007 | PA18-484 | Shaughnessy, Daniel | 30 | 09 - Genome Integrity | - |
| DEFINING THE MOLECULAR BASIS OF ONCOGENE-INDUCED REPLICATION STRESS | huang, tony tung | New York University School Of Medicine | R01ES031658 | PA19-056 | Shaughnessy, Daniel | 7 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| DNA ADDUCT DETECTION AND REPAIR IN MAMMALIAN CELLS | sancar, aziz | Univ Of North Carolina Chapel Hill | R01ES033414 | PAR19-251 | Shaughnessy, Daniel | 19 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| DNA ADDUCT-INDUCED MUTAGENESIS | stone, michael p | Vanderbilt University | R56ES029357 | PA20-185 | Shaughnessy, Daniel | 1 | 09 - Genome Integrity | - |
| DNA ADDUCTOME OF HUMAN BLADDER FROM THE TOBACCO EXPOSOME | turesky, robert j. | University Of Minnesota | R01ES030559 | PAR18-704 | Shaughnessy, Daniel | 4 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| DNA PROTEIN CROSS-LINKS:CELLULAR EFFECTS AND REPAIR MECHANISMS | tretyakova, natalia y | University Of Minnesota | R01ES023350 | PA18-484 | Shaughnessy, Daniel | 42 | 09 - Genome Integrity | - |
| DNA REPAIR PATHWAY COORDINATION DURING DAMAGE PROCESSING | schaich, matthew allen | University Of Pittsburgh At Pittsburgh | F32ES034982 | PA21-048 | Shaughnessy, Daniel | 1 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| DNA–PROTEIN CROSS-LINKING SEQUENCING FOR GENOME-WIDE MAPPING OF ABASIC SITES AT SINGLE-NUCLEOTIDE RESOLUTION | tang, feng | University Of California Riverside | K99ES035446 | PA20-188 | Shaughnessy, Daniel | 1 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| DYNAMIC DNA STRUCTURES IN BIOLOGY | mcvey, mitch | Federation Of Amer Soc For Exper Biology | R13ES036442 | PA21-151 | Shaughnessy, Daniel | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| ENVIRONMENTAL DNA LESIONS AND MUTAGENESIS: MOLECULAR MECHANISMS OF LESION RECOGNITION FOR REPAIR AND POLYMERASE BYPASS | broyde, suse | New York University | R01ES025987 | PA20-185 | Heacock, Michelle | 27 | 09 - Genome Integrity | - |
| ENVIRONMENTAL FACTORS AND COMPOUNDS AFFECTING THE GENOMIC STABILITY IN HAPLOINSUFFICIENT BRCA1 CELLS. | gerhardt, jeannine | Weill Medical Coll Of Cornell Univ | R01ES034733 | PA20-185 | Shaughnessy, Daniel | 1 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| ERROR-SUPPRESSED WHOLE GENOME SEQUENCING FOR GENOTOXICANT-INDUCED STRUCTURAL VARIANT DETECTION | wilson, thomas edward | University Of Michigan At Ann Arbor | R21ES034143 | PA20-195 | Shaughnessy, Daniel | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| EXCISION REPAIR OF ENVIRONMENTAL TELOMERE DAMAGE | opresko, patricia l | University Of Pittsburgh At Pittsburgh | R35ES030396 | ES18-004 | Heacock, Michelle | 23 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| FUNCTION OF HMCES IN ABASIC SITE REPAIR AND TOLERANCE | cortez, david k | Vanderbilt University | R01ES030575 | PA20-185 | Shaughnessy, Daniel | 9 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| GENOTOXIC STRESS RESPONSE AND MUTAGENESIS IN NORMAL TISSUES OF MICE DEFICIENT IN HOMOLOGY DIRECTED REPAIR | jackson, james | Tulane University Of Louisiana | R01ES032036 | PA20-185 | Shaughnessy, Daniel | 4 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| HOW SSB REGULATES YOAA-CHI'S FUNCTION IN DNA DAMAGE REPAIR | pollenz, savannah weeks | University Of Florida | F31ES034652 | PA21-051 | Shaughnessy, Daniel | 2 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| HYPERMUTATION IN BACTERIA AND HUMANS | goodman, myron | University Of Southern California | R35ES028343 | ES16-008 | Shaughnessy, Daniel | 16 | 09 - Genome Integrity | - |
| IDENTIFYING CHROMATIN FACTORS ESSENTIAL FOR DNA REPAIR USING A NOVEL HIGH-THROUGHPUT SCREENING METHODOLOGY | clarke, thomas l | Boston University Medical Campus | R00ES034443 | PA20-188 | Shaughnessy, Daniel | 1 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| IMPLICATION OF HISTONE H4 LRS MUTATIONS IN TRANSLESION SYNTHESIS AND UV MUTAGENESIS | li, shisheng | Louisiana State Univ A&M Col Baton Rouge | R03ES033789 | PA20-200 | Reinlib, Leslie | 3 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| INDIRECT GENOTOXICITY IN METAL CARCINOGENESIS | zhitkovich, anatoly | Brown University | R01ES031002 | PA19-056 | Tyson, Frederick | 9 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| INTEGRATING GENOMIC SIGNATURES WITH FUNCTIONAL ANALYSIS OF DNA REPAIR | nagel, zachary david | Broad Institute, Inc. | R21ES036696 | PA20-195 | Shaughnessy, Daniel | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| INTEGRATIVE MODELING OF BIOMOLECULAR MACHINERY IN NUCLEOTIDE EXCISION REPAIR | ivanov, ivaylo nikolaev | Georgia State University | R01ES032786 | PA20-185 | Shaughnessy, Daniel | 2 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| INVESTIGATING ENVIRONMENTAL RISK FACTORS FOR BREAST CANCER USING ADDUCTOMICS | funk, william e | Northwestern University At Chicago | R01ES031809 | PAR19-251 | Shaughnessy, Daniel | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| INVESTIGATING ROLES FOR OXIDATIVE GUANINE DAMAGE IN TRANSCRIPTION REGULATION | de rosa, mariarosaria | University Of Pittsburgh At Pittsburgh | K99ES035871 | PA20-188 | Heacock, Michelle | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| INVESTIGATING THE CELLULAR IMPACT OF 8-OXO-GUANINE ON DNA REPLICATION AND GENOME STABILITY | barnes, ryan p | University Of Kansas Medical Center | R00ES033771 | PA20-188 | Heacock, Michelle | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| INVESTIGATION OF HUMAN DNA POLYMERASE EPSILON VARIANTS | pursell, zachary f | Tulane University Of Louisiana | R01ES028271 | PA20-185 | Shaughnessy, Daniel | 11 | 09 - Genome Integrity | - |
| KIDNEY DNA ADDUCTOMICS | turesky, robert j. | University Of Minnesota | R01ES030765 | PA19-056 | Shaughnessy, Daniel | 3 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| LEVERAGING MUTATIONAL ANALYSIS OF CELL-FREE DNA TO IDENTIFY CARCINOGENIC EXPOSURE AND ENABLE EARLY DETECTION OF CANCER | fedeles, bogdan i | Massachusetts Institute Of Technology | R21ES036341 | PA20-195 | Shaughnessy, Daniel | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| MEASURING GENOMIC DNA DAMAGE AND DNA REPAIR CAPACITY IN LONGITUDINAL POPULATION SAMPLES - A STEP TOWARDS PRECISION PREVENTION | sobol, robert w | Brown University | U01ES029518 | ES17-006 | Boyles, Abee | 23 | 09 - Genome Integrity | - |
| MECHANISM OF EUKARYOTIC ENVIRONMENTAL MUTAGENESIS | walker, graham c | Massachusetts Institute Of Technology | R35ES028303 | ES16-008 | Shaughnessy, Daniel | 11 | 09 - Genome Integrity | - |
| MECHANISM OF RAD51C FORK PROTECTION AND ENVIRONMENTAL CARCINOGENESIS | schlacher, katharina | University Of Tx Md Anderson Can Ctr | R01ES029680 | PA16-160 | Shaughnessy, Daniel | 8 | 09 - Genome Integrity | - |
| MECHANISMS OF DNA DOUBLE-STRAND BREAK END RESECTION AND REPAIR PATHWAY CHOICE | sung, patrick | University Of Texas Hlth Science Center | R01ES007061 | PA20-185 | Mcallister, Kimberly | 139 | 09 - Genome Integrity | - |
| MECHANISMS OF REPLICATION FORK DEGRADATION IN VERTEBRATES | dewar, james m | Vanderbilt University | R01ES034847 | PA20-185 | Shaughnessy, Daniel | 1 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| MOLECULAR ARCHITECTURE OF OXIDATIVE STRESS INDUCED DOUBLE STRAND BREAK REPAIR | jamsen, joonas | Univ Of Arkansas For Med Scis | R00ES029572 | PA16-193 | Heacock, Michelle | 0 | 09 - Genome Integrity | - |
| MOLECULAR STRUCTURE OF CHROMIUM-DNA ADDUCTS | vincent, john bertram | University Of Alabama In Tuscaloosa | R15ES033800 | PAR18-714 | Shaughnessy, Daniel | 3 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| MUTATIONAL PROFILING IN HUMAN CELLS AS AN IN VITRO ALTERNATIVE TO IN VIVO MUTAGENICITY ASSESSMENTS | recio, leslie | Scitovation, Llc | R44ES035336 | PA22-176 | Shaughnessy, Daniel | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| NICKEL AND TOXIC TOPOISOMERASE I PRODUCTS | zhitkovich, anatoly | Brown University | R01ES031979 | PA20-185 | Tyson, Frederick | 8 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| NOVEL MARKERS OF EXPOSURE AND PATHWAYS OF RESPONSE TO CHROMIUM | lemos, bernardo | University Of Arizona | R01ES027981 | PA21-268 | Shaughnessy, Daniel | 14 | 09 - Genome Integrity | - |
| ONCOMETABOLITES, DNA REPAIR, AND CANCER | glazer, peter m | Yale University | R01ES005775 | PA20-185 | Shaughnessy, Daniel | 84 | 09 - Genome Integrity | - |
| R-LOOPS AT THE TELOMERE AS A TOXIC SOURCE OF GENOMIC INSTABILITY | griffith, jack d | Univ Of North Carolina Chapel Hill | R01ES031635 | PA19-056 | Heacock, Michelle | 14 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| RAD51 PARALOG FUNCTION IN CANCER PREDISPOSITION AND GENOME INTEGRITY | bernstein, kara a | University Of Pennsylvania | R01ES031796 | PA20-185 | Shaughnessy, Daniel | 10 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| REGULATION OF DNA EXCISION REPAIR IN CHROMATIN | wyrick, john j | Washington State University | R01ES028698 | PA20-185 | Shaughnessy, Daniel | 31 | 09 - Genome Integrity | - |
| REGULATION OF P53 AND CHECKPOINT SIGNALING BY CHROMIUM(VI) | zhitkovich, anatoly | Brown University | R01ES028072 | PA16-160 | Tyson, Frederick | 14 | 09 - Genome Integrity | - |
| REGULATION OF THE DNA DAMAGE RESPONSE | cimprich, karlene a | Stanford University | R56ES016486 | PA20-185 | Shaughnessy, Daniel | 0 | 09 - Genome Integrity | 01 - Basic Cellular or Molecular processes |
| REPAIR OF ENVIRONMENTALLY INDUCED MITOCHONDRIAL DNA DAMAGE | prakash, aishwarya | University Of South Alabama | R01ES030084 | ES18-001 | Shaughnessy, Daniel | 8 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| REPAIR OF OXIDATIVE DAMAGE IN G-QUADRUPLEX PROMOTER DNA | whitaker, amy michelle | Research Inst Of Fox Chase Can Ctr | R00ES031148 | PA19-130 | Heacock, Michelle | 2 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| REPLICATION FORK DYNAMICS AND REPAIR BY RAD51 PARALOGUES AFTER DNA ALKYLATION | bernstein, kara a | University Of Pennsylvania | R01ES030335 | PA18-484 | Shaughnessy, Daniel | 15 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| REPLICATION-COUPLED REPAIR: A MECHANISM FOR SURVIVING UV IRRADIATION | courcelle, justin | Portland State University | R21ES034880 | PA20-195 | Shaughnessy, Daniel | 4 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| ROLE OF AFLATOXIN-INDUCED DNA DAMAGE FORMATION AND REPAIR IN HEPATIC MUTAGENESIS | li, wentao | University Of Georgia | R00ES030015 | PA18-398 | Cui, Yuxia | 6 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| ROLE OF BASE EXCISION REPAIR IN LIMITING HEPATOCELLULAR CARCINOMAS | lloyd, r. stephen | Oregon Health & Science University | R01ES031086 | PA19-056 | Heacock, Michelle | 10 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| SHU COMPLEX AND RAD52 FUNCTION IN DNA DAMAGE RECOGNITION AND SUBSEQUENT REPAIR | hengel, sarah r | Tufts University Medford | R00ES033738 | PA20-188 | Shaughnessy, Daniel | 5 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| STRUCTURAL BASIS OF EUKARYOTIC CLAMP LOADING | remus, dirk | Sloan-Kettering Inst Can Research | R01ES036297 | PA20-185 | Shaughnessy, Daniel | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| STUDIES OF CHEMICALLY LABILE ALKYLATION DAMAGE IN DNA | lee, seongmin | University Of Texas At Austin | R01ES034781 | PA20-185 | Shaughnessy, Daniel | 1 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| TELOMERE DYSFUNCTION DRIVEN MOLECULAR OUTPUTS IN THE CARDIAC UNIT | gurkar, aditi u | University Of Pittsburgh At Pittsburgh | R01ES035733 | ES22-007 | Heacock, Michelle | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| TELOMERE UNCAPPING EPIGENETICALLY REPROGRAMS A STRESS RESPONSE AND LONGEVITY PATHWAY | ahmed, shawn cameron | Univ Of North Carolina Chapel Hill | R01ES035777 | ES22-007 | Heacock, Michelle | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| THE MUTAGENIC CONSEQUENCES OF REPLICATION-COUPLED DNA REPAIR MECHANISMS | mehta, kavi | University Of Wisconsin-Madison | R00ES034058 | PA20-188 | Shaughnessy, Daniel | 2 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| THE ROLE OF AQUAPORIN 3 IN ARSENIC-INDUCED DNA DAMAGE AND MUTAGENESIS | xia, jun | Creighton University | R00ES033259 | PA20-188 | Shaughnessy, Daniel | 6 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| THE ROLE OF CENP-A IN THE RESPONSE TO DNA DOUBLE-STRAND BREAKS | kitagawa, katsumi | University Of Texas Hlth Science Center | R21ES033354 | PA20-195 | Shaughnessy, Daniel | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| THE ROLE OF ELF1 IN TRANSCRIPTION COUPLED-NUCLEOTIDE EXCISION REPAIR | wyrick, john j | Washington State University | R21ES035888 | PA20-195 | Shaughnessy, Daniel | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| THE ROLE OF MONO-ADP-RIBOSYLATION BY PARP14 IN RADIORESISTANCE | moldovan, george lucian | Pennsylvania State Univ Hershey Med Ctr | R01ES026184 | PA20-185 | Shaughnessy, Daniel | 27 | 09 - Genome Integrity | - |
| TRANSLESION SYNTHESIS DNA POLYMERASES AND GENOME INSTABILITY | shcherbakova, polina v | University Of Nebraska Medical Center | R01ES015869 | PA18-484 | Heacock, Michelle | 23 | 09 - Genome Integrity | 01 - Basic Cellular or Molecular processes |
| UNCOVERING THE IMPACT OF OXIDATIVE STRESS ON CENTROMERE INTEGRITY | thompson, lily | Thomas Jefferson University | F31ES036105 | PA23-272 | Shaughnessy, Daniel | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| UNDERSTANDING POST TRANSLATIONAL MODIFIERS IN DNA DAMAGE REPAIR | dray, eloise | University Of Texas Hlth Science Center | R21ES035997 | PA20-195 | Heacock, Michelle | 3 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| UNDERSTANDING THE ROLE OF ULP1 AS A CLOCK FOR HETEROCHROMATIN REPAIR | butova, nadejda | University Of Southern California | F31ES036878 | PA23-272 | Shaughnessy, Daniel | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| UNRAVELING THE MOLECULAR LINK BETWEEN HEAVY METAL EXPOSURE AND TRIPLE NEGATIVE BREAST CANCER | nail, alexandra nichole | University Of Louisville | K99ES036286 | PA20-188 | Tyson, Frederick | 0 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| URINARY DNA ADDUCTOMICS FOR THE ASSESSMENT OF EXPOSURE TO CANCER RISK FACTORS | cooke, marcus stanley | University Of South Florida | R01ES030557 | PAR18-704 | Shaughnessy, Daniel | 10 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |
| WATCHING COOPERATIVE INTERACTIONS BETWEEN BASE AND NUCLEOTIDE EXCISION REPAIR PROTEINS | van houten, bennett | University Of Pittsburgh At Pittsburgh | R35ES031638 | ES19-007 | Heacock, Michelle | 24 | 09 - Genome Integrity | 03 - Carcinogenesis/Cell Transformation |