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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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Inhibition of the urea cycle by the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin in ... | Cholico, Giovan N; Fling, Russell R; Sink, Warren J; Nault, Rance; Zacharewski, Tim | P42ES004911, R01ES029541, T32ES007255 | J Biol Chem (2024 Jan) | 38013089 | 2024 |
Consequences of reprogramming acetyl-CoA metabolism by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the mo ... | Cholico, Giovan N; Orlowska, Karina; Fling, Russell R; Sink, Warren J; Zacharewski, Nicholas A; ... | P42ES004911, R01ES029541, T32ES007255 | Sci Rep (2023 Mar 13) | 36914879 | 2023 |
Cystine/Glutamate Xc- Antiporter Induction Compensates for Transsulfuration Pathway Repression by 2, ... | Orlowska, Karina; Fling, Russ R; Nault, Rance; Schilmiller, Anthony L; Zacharewski, Timothy R | P42ES004911, R01ES029541, T32ES007255 | Chem Res Toxicol (2023 Jun 19) | 37184393 | 2023 |
How single-cell transcriptomics provides insight on hepatic responses to TCDD. | Rance, Nault | P42ES004911, R01ES033898 | Curr Opin Toxicol (2023 Dec) | 37981901 | 2023 |
Involvement of the p38/MK2 Pathway in MCLR Hepatotoxicity Revealed through MAPK Pharmacological Inhi ... | Lynch, Katherine D; Iverson, Dayne T; Bachhav, Namrata K; Call, Michael Ridge; Yue, Guihua Eile ... | R01ES032558 | Int J Mol Sci (2023 Jul 06) | 37446360 | 2023 |
Renal Transporter Alterations in Patients with Chronic Liver Diseases: Nonalcoholic Steatohepatitis, ... | Frost, Kayla L; Jilek, Joseph L; Sinari, Shripad; Klein, Robert R; Billheimer, Dean; Wright, S ... | P30ES006694, R01ES028668, T32ES007091 | Drug Metab Dispos (2023 Feb) | 36328481 | 2023 |
Representative Rodent Models for Renal Transporter Alterations in Human Nonalcoholic Steatohepatitis ... | Frost, Kayla L; Jilek, Joseph L; Toth, Erica L; Goedken, Michael J; Wright, Stephen H; Cherring ... | P30ES006694, R01ES028668 | Drug Metab Dispos (2023 Aug) | 37137719 | 2023 |
Attenuated Ochratoxin A Transporter Expression in a Mouse Model of Nonalcoholic Steatohepatitis Prot ... | Jilek, Joseph L; Frost, Kayla L; Marie, Solène; Myers, Cassandra M; Goedken, Michael; Wright, ... | P30ES006694, R01ES028668, T32ES007091 | Drug Metab Dispos (2022 Oct) | 34921099 | 2022 |
Benchmarking of a Bayesian single cell RNAseq differential gene expression test for dose-response st ... | Nault, Rance; Saha, Satabdi; Bhattacharya, Sudin; Dodson, Jack; Sinha, Samiran; Maiti, Tapabra ... | P42ES004911, R01ES029541 | Nucleic Acids Res (2022 May 06) | 35061903 | 2022 |
Dioxin-elicited decrease in cobalamin redirects propionyl-CoA metabolism to the β-oxidation-like pat ... | Orlowska, Karina; Fling, Russ R; Nault, Rance; Sink, Warren J; Schilmiller, Anthony L; Zacharew ... | P42ES004911, R01ES029541, R01ES033898, T32ES007255 | J Biol Chem (2022 Sep) | 35931118 | 2022 |
Genome-Wide ChIPseq Analysis of AhR, COUP-TF, and HNF4 Enrichment in TCDD-Treated Mouse Liver. | Cholico, Giovan N; Nault, Rance; Zacharewski, Tim R | P42ES004911, R01ES029541, T32ES007255 | Int J Mol Sci (2022 Jan 29) | 35163483 | 2022 |
Increased Renal Expression of Complement Components in Patients With Liver Diseases: Nonalcoholic St ... | Frost, Kayla L; Jilek, Joseph L; Thompson, Austin D; Klein, Robert R; Sinari, Shripad; Torabzed ... | P30ES006694, R01ES028668, T32ES007091 | Toxicol Sci (2022 Aug 25) | 35789393 | 2022 |
Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier. | Hau, Raymond K; Klein, Robert R; Wright, Stephen H; Cherrington, Nathan J | P30ES006694, R01ES028668, T32ES007091 | Drug Metab Dispos (2022 Jun) | 35307651 | 2022 |
PF-07321332 (Nirmatrelvir) does not interact with human ENT1 or ENT2: Implications for COVID-19 pati ... | Hau, Raymond K; Wright, Stephen H; Cherrington, Nathan J | R01ES028668, T32ES007091 | Clin Transl Sci (2022 Jul) | 35505633 | 2022 |
Physiological Characterization of the Transporter-Mediated Uptake of the Reversible Male Contracepti ... | Hau, Raymond K; Tash, Joseph S; Georg, Gunda I; Wright, Stephen H; Cherrington, Nathan J | R01ES028668, T32ES007091 | J Pharmacol Exp Ther (2022 Sep) | 35779861 | 2022 |
Role of Lung P450 Oxidoreductase in Paraquat-Induced Collagen Deposition in the Lung. | Kovalchuk, Nataliia; Jilek, Joseph L; Van Winkle, Laura S; Cherrington, Nathan J; Ding, Xinxin | P30ES006694, P30ES023513, R01ES020867, R01ES028668, T32ES007091 | Antioxidants (Basel) (2022 Jan 24) | 35204102 | 2022 |
Strategies to Diagnose Nonalcoholic Steatohepatitis: A Novel Approach to Take Advantage of Pharmacok ... | Marie, Solène; Tripp, David K K; Cherrington, Nathan J | P30ES006694, R01ES028668 | Drug Metab Dispos (2022 Apr) | 34531312 | 2022 |
Aryl Hydrocarbon Receptor (AhR) Activation by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) Dose-Depend ... | Fling, Russell R; Zacharewski, Timothy R | P42ES004911, R01ES029541, T32ES007255 | Int J Mol Sci (2021 Nov 18) | 34830313 | 2021 |
Genetics-Based Approach to Identify Novel Genes Regulated by the Aryl Hydrocarbon Receptor in Mouse ... | Jurgelewicz, Amanda; Dornbos, Peter; Warren, Melanie; Nault, Rance; Arkatkar, Anooj; Lin, Hui; ... | P42ES004911, R01ES029541, T32ES007255 | Toxicol Sci (2021 May 27) | 33720361 | 2021 |
MCLR-elicited hepatic fibrosis and carcinogenic gene expression changes persist in rats with diet-in ... | Arman, Tarana; Baron, J Allen; Lynch, Katherine D; White, Laura A; Aldan, Johnny; Clarke, John ... | R01ES032558 | Toxicology (2021 Dec) | 34740672 | 2021 |
Microcystin Toxicokinetics, Molecular Toxicology, and Pathophysiology in Preclinical Rodent Models a ... | Arman, Tarana; Clarke, John D | R01ES032558 | Toxins (Basel) (2021 07 29) | 34437407 | 2021 |
Single-Nuclei RNA Sequencing Assessment of the Hepatic Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxi ... | Nault, Rance; Fader, Kelly A; Bhattacharya, Sudin; Zacharewski, Tim R | P42ES004911, R01ES029541 | Cell Mol Gastroenterol Hepatol (2021) | 32791302 | 2021 |
Thioesterase induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin results in a futile cycle that inhibit ... | Cholico, Giovan N; Fling, Russell R; Zacharewski, Nicholas A; Fader, Kelly A; Nault, Rance; Zac ... | P42ES004911, R01ES029541, T32ES007255 | Sci Rep (2021 Aug 03) | 34344994 | 2021 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) dysregulates hepatic one carbon metabolism during the pro ... | Fling, Russell R; Doskey, Claire M; Fader, Kelly A; Nault, Rance; Zacharewski, Tim R | P42ES004911, R01ES029541, T32ES007255 | Sci Rep (2020 Sep 09) | 32908189 | 2020 |
Interaction of Oatp1b2 expression and nonalcoholic steatohepatitis on pravastatin plasma clearance. | Toth, Erica L; Clarke, John D; Csanaky, Iván L; Cherrington, Nathan J | P30ES006694, R01ES028668, T32ES007091 | Biochem Pharmacol (2020 04) | 31881192 | 2020 |
Folate receptor-beta expression as a diagnostic target in human & rodent nonalcoholic steatohepatiti ... | Lake, April D; Hardwick, Rhiannon N; Leamon, Christopher P; Low, Philip S; Cherrington, Nathan ... | P30ES006694, R01ES028668, T32ES007091 | Toxicol Appl Pharmacol (2019 Apr 01) | 30794826 | 2019 |
Gene-by-Environment Interaction of Bcrp-/- and Methionine- and Choline-Deficient Diet-Induced Nonalc ... | Toth, Erica L; Li, Hui; Dzierlenga, Anika L; Clarke, John D; Vildhede, Anna; Goedken, Michael; ... | P30ES006694, R01ES028668, T32ES007091 | Drug Metab Dispos (2018 Nov) | 30166404 | 2018 |