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Who We Fund: Publications associated with Organ Systems Or Disease Processes Research - Mitochondrial Disorders

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 61 publications
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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Arsenic activates STAT3 signaling during the transformation of the human bronchial epithelial cells.   Almutairy, Bandar; Fu, Yao; Bi, Zhuoyue; Zhang, Wenxuan; Wadgaonkar, Priya; Qiu, Yiran; Thakur ... R01ES028263, R01ES028335, R01ES031822 Toxicol Appl Pharmacol (2022 02 01) 35031324 Exiting the NIEHS site 2022 
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology.   Sies, Helmut; Belousov, Vsevolod V; Chandel, Navdeep S; Davies, Michael J; Jones, Dean P; Mann, ... P30ES019776, R21ES031824 Nat Rev Mol Cell Biol (2022 07) 35190722 Exiting the NIEHS site 2022 
Heterozygous p.Y955C mutation in DNA polymerase γ leads to alterations in bioenergetics, complex I s ...   Rahman, Md Mostafijur; Young, Carolyn K J; Goffart, Steffi; Pohjoismäki, Jaakko L O; Young, Mat ... R15ES033394, R15ES033394 J Biol Chem (2022 Aug) 35760101 Exiting the NIEHS site 2022 
Identification of Somatic Mitochondrial DNA Mutations, Heteroplasmy, and Increased Levels of Catenan ...   Young, Matthew J; Sachidanandam, Ravi; Hales, Dale B; Brard, Laurent; Robinson, Kathy; Rahman, ... R15ES033394, R15ES033394 Life (Basel) (2022 Apr 09) 35455053 Exiting the NIEHS site 2022 
Low-Dose Cadmium Potentiates Metabolic Reprogramming Following Early-Life Respiratory Syncytial Viru ...   Jarrell, Zachery R; Smith, Matthew Ryan; Kim, Ki-Hye; Lee, Youri; Hu, Xin; He, Xiaojia; Orr, ... P30ES019776, R01ES031980, R21ES031824, T32ES012870 Toxicol Sci (2022 06 28) 35512398 Exiting the NIEHS site 2022 
Metabolomic dynamics of the arsenic-transformed bronchial epithelial cells and the derived cancer st ...   Fu, Yao; Bi, Zhuoyue; Li, Lingzhi; Wadgaonkar, Priya; Qiu, Yiran; Almutairy, Bandar; Zhang, W ... R01ES028263, R01ES028335, R01ES031822 Int J Biol Sci (2022) 34975334 Exiting the NIEHS site 2022 
Plasma concentrations of lipophilic persistent organic pollutants and glucose homeostasis in youth p ...   Baumert, Brittney O; Goodrich, Jesse A; Hu, Xin; Walker, Douglas I; Alderete, Tanya L; Chen, Z ... K12ES033594, P30ES007048, P30ES019776, P30ES023515, R00ES027870, R01ES029944, R01ES030364, R01ES030691, R01ES032189, R01ES032189, R21ES029328, R21ES029681, R21ES031824, R24ES029490, T32ES013678 Environ Res (2022 09) 35447156 Exiting the NIEHS site 2022 
Preliminary Research: Application of Non-Invasive Measure of Cytochrome c Oxidase Redox States and M ...   Lewis, Alistair T; Forti, Rodrigo M; Alomaja, Oladunni; Mesaros, Clementina; Piel, Sarah; Green ... P30ES013508, R21ES031243 J Med Toxicol (2022 07) 35482181 Exiting the NIEHS site 2022 
Scinderin promotes fusion of electron transport chain dysfunctional muscle stem cells with myofibers ...   Wang, Xun; Shelton, Spencer D; Bordieanu, Bogdan; Frank, Anderson R; Yi, Yating; Venigalla, Si ... DP2ES030449 Nat Aging (2022) 35342888 Exiting the NIEHS site 2022 
Secreted Proteins, Lipids and Low-Molecular-Weight Metabolites as Early Biomarkers of Human Proximal ...   Lash, Lawrence H; Mathieu, Patricia; Stemmer, Paul M; Rosati, Rita; Hu, Xin; Jones, Dean P R01ES031584 FASEB J (2022 May) 35553005 Exiting the NIEHS site 2022 
Solution Chemistry of Dihydroxyacetone and Synthesis of Monomeric Dihydroxyacetone.   Belfleur, Luxene; Sonavane, Manoj; Hernandez, Arlet; Gassman, Natalie R; Migaud, Marie E R01ES032450 Chem Res Toxicol (2022 04 18) 35324152 Exiting the NIEHS site 2022 
The role of Iron in lipid peroxidation and protein nitration during acetaminophen-induced liver inju ...   Adelusi, Olamide B; Ramachandran, Anup; Lemasters, John J; Jaeschke, Hartmut R21ES031335 Toxicol Appl Pharmacol (2022 06 15) 35513057 Exiting the NIEHS site 2022 
The UPRmt preserves mitochondrial import to extend lifespan.   Xin, Nan; Durieux, Jenni; Yang, Chunxia; Wolff, Suzanne; Kim, Hyun-Eui; Dillin, Andrew R01ES021667 J Cell Biol (2022 07 04) 35608535 Exiting the NIEHS site 2022 
Alterations in cerebral and cardiac mitochondrial function in a porcine model of acute carbon monoxi ...   Jang, David H; Piel, Sarah; Greenwood, John C; Kelly, Matthew; Mazandi, Vanessa M; Ranganathan, ... R21ES031243 Clin Toxicol (Phila) (2021 Sep) 33529085 Exiting the NIEHS site 2021 
Connections between endoplasmic reticulum stress-associated unfolded protein response, mitochondria, ...   Wadgaonkar, Priya; Chen, Fei P30ES020957, R01ES028263, R01ES028335, R01ES031822 Semin Cancer Biol (2021 11) 33836253 Exiting the NIEHS site 2021 
Cooperation between NRF2-mediated transcription and MDIG-dependent epigenetic modifications in arsen ...   Bi, Zhuoyue; Zhang, Qian; Fu, Yao; Seno, Akimasa; Wadgaonkar, Priya; Qiu, Yiran; Almutairy, B ... R01ES028263, R01ES028335, R01ES031822 Semin Cancer Biol (2021 11) 33823236 Exiting the NIEHS site 2021 
Cross-species screening platforms identify EPS-8 as a critical link for mitochondrial stress and act ...   Moehle, Erica A; Higuchi-Sanabria, Ryo; Tsui, C Kimberly; Homentcovschi, Stefan; Tharp, Kevin M ... R01ES021667 Sci Adv (2021 Oct 29) 34714674 Exiting the NIEHS site 2021 
Diverse Roles of Mitochondria in Renal Injury from Environmental Toxicants and Therapeutic Drugs.   Lash, Lawrence H R01ES031584 Int J Mol Sci (2021 Apr 17) 33920653 Exiting the NIEHS site 2021 
Emerging cellular-based therapies in carbon monoxide poisoning.   Jang, David H; Piel, Sarah; Greenwood, John C; Ehinger, Johannes K; Kilbaugh, Todd J P30ES013508, R21ES031243 Am J Physiol Cell Physiol (2021 08 01) 34133239 Exiting the NIEHS site 2021 
Environmentally-induced mdig contributes to the severity of COVID-19 through fostering expression of ...   Zhang, Qian; Wadgaonkar, Priya; Xu, Liping; Thakur, Chitra; Fu, Yao; Bi, Zhuoyue; Qiu, Yiran; ... R01ES028263, R01ES028335, R01ES031822 Theranostics (2021) 34335974 Exiting the NIEHS site 2021 
Exogenous exposure to dihydroxyacetone mimics high fructose induced oxidative stress and mitochondri ...   Mehta, Raj; Sonavane, Manoj; Migaud, Marie E; Gassman, Natalie R R01ES032450 Environ Mol Mutagen (2021 03) 33496975 Exiting the NIEHS site 2021 
Firsthand and Secondhand Exposure Levels of Maltol-Flavored Electronic Nicotine Delivery System Vapo ...   Jarrell, Zachery R; Smith, Matthew Ryan; He, Xiaojia; Orr, Michael; Jones, Dean P; Go, Young-M ... P30ES019776, R21ES031824, T32ES012870 Toxicol Sci (2021 07 16) 34009373 Exiting the NIEHS site 2021 
Landing a Successful R or K Grant: a Young Investigator's Journey.   Jang, David H; Kilbaugh, Todd J R21ES031243 J Med Toxicol (2021 04) 33410114 Exiting the NIEHS site 2021 
Lung metabolome of 1,3-butadiene exposed Collaborative Cross mice reflects metabolic phenotype of hu ...   Nellis, Mary; Caperton, Caitlin O; Liu, Ken; Tran, ViLinh; Go, Young-Mi; Hallberg, Lance M; Am ... P30ES019776, P30ES030285, R21ES031824, T32ES007254 Toxicology (2021 11) 34648870 Exiting the NIEHS site 2021 
Metabolic implications of non-electrogenic ATP/ADP exchange in cancer cells: A mechanistic basis for ...   Lemasters, John J R21ES031335 Biochim Biophys Acta Bioenerg (2021 07 01) 33722515 Exiting the NIEHS site 2021 
Metabolome-wide association study of flavorant vanillin exposure in bronchial epithelial cells revea ...   Smith, Matthew Ryan; Jarrell, Zachery R; Orr, Michael; Liu, Ken H; Go, Young-Mi; Jones, Dean P P30ES019776, R21ES031824, T32ES012870 Environ Int (2021 02) 33360165 Exiting the NIEHS site 2021 
Metabolomics as a Truly Translational Tool for Precision Medicine.   Schmidt, Julian C; Dougherty, Bonnie V; Beger, Richard D; Jones, Dean P; Schmidt, Michael A; Ma ... P30ES019776, R01ES032189, R01ES032189, R21ES031824, R24ES029490 Int J Toxicol (2021 10) 34514887 Exiting the NIEHS site 2021 
Microbial metabolite delta-valerobetaine is a diet-dependent obesogen.   Liu, Ken H; Owens, Joshua A; Saeedi, Bejan; Cohen, Catherine E; Bellissimo, Moriah P; Naudin, ... P30ES019776, R21ES031824 Nat Metab (2021 12) 34931082 Exiting the NIEHS site 2021 
Pathological and Prognostic Indications of the mdig Gene in Human Lung Cancer.   Shi, Junwei; Thakur, Chitra; Zhao, Yuzu; Li, Yongsen; Nie, Lishen; Zhang, Qian; Bi, Zhuoyue; ... P30ES020957, R01ES028263, R01ES028335 Cell Physiol Biochem (2021 Jan 11) 33423409 Exiting the NIEHS site 2021 
Characterization of Arsenic-Induced Cancer Stem-Like Cells.   Chang, Qingshan; Bi, Zhuoyue; Fu, Yao; Rice, M' Kya Anique; Zhang, Qian; Wadgaonkar, Priya; Al ... R01ES028263, R01ES028335 Methods Mol Biol (2020) 31960388 Exiting the NIEHS site 2020 
CRISPR-Cas9 gene editing causes alternative splicing of the targeting mRNA.   Zhang, Qian; Fu, Yao; Thakur, Chitra; Bi, Zhuoyue; Wadgaonkar, Priya; Qiu, Yiran; Xu, Liping; ... P30ES020957, R01ES028263, R01ES028335 Biochem Biophys Res Commun (2020 07 12) 32460957 Exiting the NIEHS site 2020 
Ex vivo use of cell-permeable succinate prodrug attenuates mitochondrial dysfunction in blood cells ...   Owiredu, Shawn; Ranganathan, Abhay; Eckmann, David M; Shofer, Frances S; Hardy, Kevin; Lambert, ... R21ES031243 Am J Physiol Cell Physiol (2020 07 01) 32374677 Exiting the NIEHS site 2020 
Measurements of Physiological Stress Responses in C. Elegans.   Bar-Ziv, Raz; Frakes, Ashley E; Higuchi-Sanabria, Ryo; Bolas, Theodore; Frankino, Phillip A; Gi ... R01ES021667 J Vis Exp (2020 05 21) 32510480 Exiting the NIEHS site 2020 
Nrf2 and HIF1α converge to arsenic-induced metabolic reprogramming and the formation of the cancer s ...   Bi, Zhuoyue; Zhang, Qian; Fu, Yao; Wadgaonkar, Priya; Zhang, Wenxuan; Almutairy, Bandar; Xu, ... P30ES020957, R01ES028263, R01ES028335 Theranostics (2020) 32226544 Exiting the NIEHS site 2020 
The management of the poisoned patient using a novel emergency department-based resuscitation and cr ...   Mudan, Anita; Love, Jennifer S; Greenwood, John C; Stickley, Carolyn; Zhou, Victoria L; Shofer, ... R21ES031243 Am J Emerg Med (2020 10) 33142177 Exiting the NIEHS site 2020 
Connections between metabolism and epigenetics in cancers.   Thakur, Chitra; Chen, Fei R01ES028263, R01ES028335 Semin Cancer Biol (2019 08) 31185282 Exiting the NIEHS site 2019 
Linking metabolism to epigenetics in stem cells and cancer stem cells.   Chen, Fei P30ES020957, R01ES028263, R01ES028335 Semin Cancer Biol (2019 08) 31078639 Exiting the NIEHS site 2019 
Metabolic and epigenetic reprogramming in the arsenic-induced cancer stem cells.   Li, Lingzhi; Bi, Zhuoyue; Wadgaonkar, Priya; Lu, Yongju; Zhang, Qian; Fu, Yao; Thakur, Chitra ... P30ES020957, R01ES028263, R01ES028335 Semin Cancer Biol (2019 08) 31009762 Exiting the NIEHS site 2019 
New discoveries of mdig in the epigenetic regulation of cancers.   Zhang, Qian; Thakur, Chitra; Shi, Junwei; Sun, Jiaying; Fu, Yao; Stemmer, Paul; Chen, Fei P30ES020957, R01ES028263 Semin Cancer Biol (2019 08) 31276784 Exiting the NIEHS site 2019 
Loss of mdig expression enhances DNA and histone methylation and metastasis of aggressive breast can ...   Thakur, Chitra; Chen, Bailing; Li, Lingzhi; Zhang, Qian; Yang, Zeng-Quan; Chen, Fei P30ES020957, R01ES028263 Signal Transduct Target Ther (2018) 30254753 Exiting the NIEHS site 2018 
Mitochondrial Subtype Identification and Characterization.   Daniele, Joseph R; Heydari, Kartoosh; Dillin, Andrew R01ES021667 Curr Protoc Cytom (2018 07) 29944197 Exiting the NIEHS site 2018 
The Mitochondrial Unfolded Protein Response Is Mediated Cell-Non-autonomously by Retromer-Dependent ...   Zhang, Qian; Wu, Xueying; Chen, Peng; Liu, Limeng; Xin, Nan; Tian, Ye; Dillin, Andrew R01ES021667 Cell (2018 08 09) 30057120 Exiting the NIEHS site 2018 
Lipid Biosynthesis Coordinates a Mitochondrial-to-Cytosolic Stress Response.   Kim, Hyun-Eui; Grant, Ana Rodrigues; Simic, Milos S; Kohnz, Rebecca A; Nomura, Daniel K; Durieu ... R01ES021667 Cell (2016 Sep 08) 27610574 Exiting the NIEHS site 2016 
Neuroendocrine Coordination of Mitochondrial Stress Signaling and Proteostasis.   Berendzen, Kristen M; Durieux, Jenni; Shao, Li-Wa; Tian, Ye; Kim, Hyun-Eui; Wolff, Suzanne; Li ... R01ES021667 Cell (2016 Sep 08) 27610575 Exiting the NIEHS site 2016 
Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity.   Merkwirth, Carsten; Jovaisaite, Virginija; Durieux, Jenni; Matilainen, Olli; Jordan, Sabine D; ... R01ES021667 Cell (2016 May 19) 27133168 Exiting the NIEHS site 2016 
Endocrine aspects of organelle stress—cell non-autonomous signaling of mitochondria and the ER.   Schinzel, Robert; Dillin, Andrew R01ES021667 Curr Opin Cell Biol (2015 Apr) 25677685 Exiting the NIEHS site 2015 
Heterotypic Signals from Neural HSF-1 Separate Thermotolerance from Longevity.   Douglas, Peter M; Baird, Nathan A; Simic, Milos S; Uhlein, Sarah; McCormick, Mark A; Wolff, Su ... R01ES021667 Cell Rep (2015 Aug 18) 26257177 Exiting the NIEHS site 2015 
Phosphorylation of LC3 by the Hippo kinases STK3/STK4 is essential for autophagy.   Wilkinson, Deepti S; Jariwala, Jinel S; Anderson, Ericka; Mitra, Koyel; Meisenhelder, Jill; Cha ... R01ES021667 Mol Cell (2015 Jan 08) 25544559 Exiting the NIEHS site 2015 
The Deubiquitylase MATH-33 Controls DAF-16 Stability and Function in Metabolism and Longevity.   Heimbucher, Thomas; Liu, Zheng; Bossard, Carine; McCloskey, Richard; Carrano, Andrea C; Riedel, ... R01ES021667 Cell Metab (2015 Jul 7) 26154057 Exiting the NIEHS site 2015 
A Krüppel-like factor downstream of the E3 ligase WWP-1 mediates dietary-restriction-induced longevi ...   Carrano, Andrea C; Dillin, Andrew; Hunter, Tony R01ES021667 Nat Commun (2014 May 08) 24805825 Exiting the NIEHS site 2014 
Differential scales of protein quality control.   Wolff, Suzanne; Weissman, Jonathan S; Dillin, Andrew R01ES021667 Cell (2014 Mar 27) 24679526 Exiting the NIEHS site 2014 
Meta-analysis of global metabolomic data identifies metabolites associated with life-span extension.   Patti, Gary J; Tautenhahn, Ralf; Johannsen, Darcy; Kalisiak, Ewa; Ravussin, Eric; Brüning, Jen ... R01ES021667 Metabolomics (2014 Aug 1) 25530742 Exiting the NIEHS site 2014 
Profile of Kazutoshi Mori and Peter Walter, 2014 Lasker Basic Medical Research awardees: The unfolde ...   Dillin, Andrew R01ES021667 Proc Natl Acad Sci U S A (2014 Dec 16) 25480547 Exiting the NIEHS site 2014 
The disposable soma theory of aging in reverse.   Douglas, Peter M; Dillin, Andrew R01ES021667 Cell Res (2014 Jan) 24189044 Exiting the NIEHS site 2014 
DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity.   Riedel, Christian G; Dowen, Robert H; Lourenco, Guinevere F; Kirienko, Natalia V; Heimbucher, T ... R01ES021667 Nat Cell Biol (2013 May) 23604319 Exiting the NIEHS site 2013 
The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans.   Lapierre, Louis R; De Magalhaes Filho, C Daniel; McQuary, Philip R; Chu, Chu-Chiao; Visvikis, O ... R01ES021667 Nat Commun (2013) 23925298 Exiting the NIEHS site 2013 
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.   Russell, Ryan C; Tian, Ye; Yuan, Haixin; Park, Hyun Woo; Chang, Yu-Yun; Kim, Joungmok; Kim, H ... R01ES021667 Nat Cell Biol (2013 Jul) 23685627 Exiting the NIEHS site 2013 
Expanding the genetic code of Caenorhabditis elegans using bacterial aminoacyl-tRNA synthetase/tRNA ...   Parrish, Angela R; She, Xingyu; Xiang, Zheng; Coin, Irene; Shen, Zhouxin; Briggs, Steven P; Di ... R01ES021667 ACS Chem Biol (2012 Jul 20) 22554080 Exiting the NIEHS site 2012 
Temporal requirements of heat shock factor-1 for longevity assurance.   Volovik, Yuli; Maman, Moria; Dubnikov, Tatyana; Bejerano-Sagie, Michal; Joyce, Derek; Kapernick ... R01ES021667 Aging Cell (2012 Jun) 22360389 Exiting the NIEHS site 2012 
Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia ...   Kim, Hyungsoo; Scimia, Maria C; Wilkinson, Deepti; Trelles, Ramon D; Wood, Malcolm R; Bowtell, ... R01ES021667 Mol Cell (2011 Nov 18) 22099302 Exiting the NIEHS site 2011 
Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by ...   Sancak, Yasemin; Bar-Peled, Liron; Zoncu, Roberto; Markhard, Andrew L; Nada, Shigeyuki; Sabatin ... DP2ES032761 Cell (2010 Apr 16) 20381137 Exiting the NIEHS site 2010 
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