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Who We Fund: Publications associated with Application Of Technology To Disease - Imaging

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 35 publications
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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Chemical Sensors and Imaging: Molecular, Materials, and Biological Platforms.   Messina, Marco S; Chang, Christopher J R01ES028096 ACS Cent Sci (2023 Sep 27) 37780366 Exiting the NIEHS site 2023 
Interface of biomolecular condensates modulates redox reactions.   Dai, Yifan; Chamberlayne, Christian F; Messina, Marco S; Chang, Christopher J; Zare, Richard N; ... R01ES028096 Chem (2023 Jun 08) 37546704 Exiting the NIEHS site 2023 
LOV thy neighbor: Mapping protein interactomes by genetically encodable photoproximity labeling.   Xie, Xiao; Jiang, Yishu; Chang, Christopher J R01ES028096 Proc Natl Acad Sci U S A (2023 May 16) 37155840 Exiting the NIEHS site 2023 
Metalloallostery and Transition Metal Signaling: Bioinorganic Copper Chemistry Beyond Active Sites.   Pham, Vanha N; Chang, Christopher J R01ES028096 Angew Chem Int Ed Engl (2023 Mar 06) 36653724 Exiting the NIEHS site 2023 
Neuroinflammation and white matter alterations in occupational manganese exposure assessed by diffus ...   Criswell, Susan R; Nielsen, Susan Searles; Faust, Irene M; Shimony, Joshua S; White 3rd, Robert ... R01ES021488, R01ES029524 Neurotoxicology (2023 Jul) 37127223 Exiting the NIEHS site 2023 
Activity-Based Sensing for Chemistry-Enabled Biology: Illuminating Principles, Probes, and Prospects ...   Messina, Marco S; Quargnali, Gianluca; Chang, Christopher J R01ES028096 ACS Bio Med Chem Au (2022 Dec 21) 36573097 Exiting the NIEHS site 2022 
Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo.   Murphy, Michael P; Bayir, Hülya; Belousov, Vsevolod; Chang, Christopher J; Davies, Kelvin J A; ... R01ES028096 Nat Metab (2022 Jun) 35760871 Exiting the NIEHS site 2022 
Head tremor in cervical dystonia: Quantifying severity with computer vision.   Vu, Jeanne P; Cisneros, Elizabeth; Lee, Ha Yeon; Le, Linh; Chen, Qiyu; Guo, Xiaoyan A; Rouzbeh ... R01ES029524 J Neurol Sci (2022 Mar 15) 35101766 Exiting the NIEHS site 2022 
Protracted course progressive supranuclear palsy.   Couto, Blas; Martinez-Valbuena, Ivan; Lee, Seojin; Alfradique-Dunham, Isabel; Perrin, Richard J ... R01ES029524 Eur J Neurol (2022 Aug) 35384155 Exiting the NIEHS site 2022 
A microtubule-localizing activity-based sensing fluorescent probe for imaging hydrogen peroxide in l ...   Jia, Shang; Chang, Christopher J R01ES028096 Bioorg Med Chem Lett (2021 09 15) 34245851 Exiting the NIEHS site 2021 
A tandem activity-based sensing and labeling strategy enables imaging of transcellular hydrogen pero ...   Iwashita, Hidefumi; Castillo, Erika; Messina, Marco S; Swanson, Raymond A; Chang, Christopher J P42ES004705, R01ES028096 Proc Natl Acad Sci U S A (2021 03 02) 33622793 Exiting the NIEHS site 2021 
Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product func ...   Luo, Mai; Spradlin, Jessica N; Boike, Lydia; Tong, Bingqi; Brittain, Scott M; McKenna, Jeffrey ... R01ES028096 Cell Chem Biol (2021 04 15) 33513350 Exiting the NIEHS site 2021 
Depression and anxiety in a manganese-exposed community.   Racette, Brad A; Nelson, Gill; Dlamini, Wendy W; Hershey, Tamara; Prathibha, Pradeep; Turner, ... P42ES023716, R01ES026246, R01ES026891, R01ES029509, R01ES029524, R01ES030937, R25ES025503 Neurotoxicology (2021 07) 34087333 Exiting the NIEHS site 2021 
Is Levodopa Response a Valid Indicator of Parkinson's Disease?   Martin, W R Wayne; Miles, Michael; Zhong, Qiaonan; Hartlein, Johanna; Racette, Brad A; Norris, ... R01ES026891, R01ES029524, R01ES030937 Mov Disord (2021 04) 33253432 Exiting the NIEHS site 2021 
Principal Component Analysis of Striatal and Extrastriatal D2 Dopamine Receptor Positron Emission To ...   Criswell, Susan R; Searles Nielsen, Susan; Dlamini, Wendy W; Warden, Mark N; Perlmutter, Joel S ... R01ES021488, R01ES029524 Toxicol Sci (2021 07 16) 33881537 Exiting the NIEHS site 2021 
Resting-State Functional Connectivity Predicts STN DBS Clinical Response.   Younce, John R; Campbell, Meghan C; Hershey, Tamara; Tanenbaum, Aaron B; Milchenko, Mikhail; Us ... R01ES029524 Mov Disord (2021 Mar) 33211330 Exiting the NIEHS site 2021 
[11C]dihydrotetrabenazine Positron Emission Tomography in Manganese-Exposed Workers.   Criswell, Susan R; Nielsen, Susan Searles; Warden, Mark N; Perlmutter, Joel S; Moerlein, Stephe ... R01ES021488, R01ES025792, R01ES025792, R01ES026891, R01ES029524 J Occup Environ Med (2020 10) 32472844 Exiting the NIEHS site 2020 
A Surge of DNA Damage Links Transcriptional Reprogramming and Hematopoietic Deficit in Fanconi Anemi ...   Shen, Xi; Wang, Rui; Kim, Moon Jong; Hu, Qianghua; Hsu, Chih-Chao; Yao, Jun; Klages-Mundt, Na ... P42ES004705, R01ES028096 Mol Cell (2020 12 17) 33338401 Exiting the NIEHS site 2020 
Activity-Based Sensing: A Synthetic Methods Approach for Selective Molecular Imaging and Beyond.   Bruemmer, Kevin J; Crossley, Steven W M; Chang, Christopher J P42ES004705, R01ES028096 Angew Chem Int Ed Engl (2020 Aug 10) 31605413 Exiting the NIEHS site 2020 
Carbon Monoxide, a Retrograde Messenger Generated in Postsynaptic Mushroom Body Neurons, Evokes Nonc ...   Ueno, Kohei; Morstein, Johannes; Ofusa, Kyoko; Naganos, Shintaro; Suzuki-Sawano, Ema; Minegishi ... P42ES004705, R01ES028096 J Neurosci (2020 04 29) 32253360 Exiting the NIEHS site 2020 
Distinct RNA N-demethylation pathways catalyzed by nonheme iron ALKBH5 and FTO enzymes enable regula ...   Toh, Joel D W; Crossley, Steven W M; Bruemmer, Kevin J; Ge, Eva J; He, Dan; Iovan, Diana A; Ch ... P42ES004705, R01ES028096 Proc Natl Acad Sci U S A (2020 10 13) 32989163 Exiting the NIEHS site 2020 
Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem ...   Coles, Garry L; Cristea, Sandra; Webber, James T; Levin, Rebecca S; Moss, Steven M; He, Andy; ... R01ES028096 Cancer Cell (2020 07 13) 32531271 Exiting the NIEHS site 2020 
Activity-Based Sensing Methods for Monitoring the Reactive Carbon Species Carbon Monoxide and Formal ...   Ohata, Jun; Bruemmer, Kevin J; Chang, Christopher J R01ES028096 Acc Chem Res (2019 Oct 15) 31487154 Exiting the NIEHS site 2019 
Bioinspired Thiophosphorodichloridate Reagents for Chemoselective Histidine Bioconjugation.   Jia, Shang; He, Dan; Chang, Christopher J P42ES004705, R01ES028096 J Am Chem Soc (2019 05 08) 31017395 Exiting the NIEHS site 2019 
Caged luciferins for bioluminescent activity-based sensing.   Su, Timothy A; Bruemmer, Kevin J; Chang, Christopher J P42ES004705, R01ES028096 Curr Opin Biotechnol (2019 12) 31200275 Exiting the NIEHS site 2019 
Covalent targeting of the vacuolar H+-ATPase activates autophagy via mTORC1 inhibition.   Chung, Clive Yik-Sham; Shin, Hijai R; Berdan, Charles A; Ford, Breanna; Ward, Carl C; Olzmann, ... P42ES004705, R01ES028096 Nat Chem Biol (2019 Aug) 31285595 Exiting the NIEHS site 2019 
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation.   Spradlin, Jessica N; Hu, Xirui; Ward, Carl C; Brittain, Scott M; Jones, Michael D; Ou, Lisha; ... P42ES004705, R01ES028096 Nat Chem Biol (2019 07) 31209351 Exiting the NIEHS site 2019 
Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells.   Berdan, Charles A; Ho, Raymond; Lehtola, Haley S; To, Milton; Hu, Xirui; Huffman, Tucker R; Pe ... P42ES004705, R01ES028096 Cell Chem Biol (2019 07 18) 31080076 Exiting the NIEHS site 2019 
Chemiluminescent Probes for Activity-Based Sensing of Formaldehyde Released from Folate Degradation ...   Bruemmer, Kevin J; Green, Ori; Su, Timothy A; Shabat, Doron; Chang, Christopher J R01ES028096 Angew Chem Int Ed Engl (2018 06 18) 29635731 Exiting the NIEHS site 2018 
Chemoproteomics-Enabled Covalent Ligand Screening Reveals ALDH3A1 as a Lung Cancer Therapy Target.   Counihan, Jessica L; Wiggenhorn, Amanda L; Anderson, Kimberly E; Nomura, Daniel K P42ES004705, R01ES028096 ACS Chem Biol (2018 Aug 17) 30004670 Exiting the NIEHS site 2018 
A 2-aza-Cope reactivity-based platform for ratiometric fluorescence imaging of formaldehyde in livin ...   Brewer, Thomas F; Burgos-Barragan, Guillermo; Wit, Niek; Patel, Ketan J; Chang, Christopher J R01ES028096 Chem Sci (2017 May 01) 28580121 Exiting the NIEHS site 2017 
Covalent Ligand Discovery against Druggable Hotspots Targeted by Anti-cancer Natural Products.   Grossman, Elizabeth A; Ward, Carl C; Spradlin, Jessica N; Bateman, Leslie A; Huffman, Tucker R; ... R01ES028096 Cell Chem Biol (2017 Nov 16) 28919038 Exiting the NIEHS site 2017 
Development of a General Aza-Cope Reaction Trigger Applied to Fluorescence Imaging of Formaldehyde i ...   Bruemmer, Kevin J; Walvoord, Ryan R; Brewer, Thomas F; Burgos-Barragan, Guillermo; Wit, Niek; P ... R01ES028096 J Am Chem Soc (2017 04 19) 28375637 Exiting the NIEHS site 2017 
Fluorescent probes for imaging formaldehyde in biological systems.   Bruemmer, Kevin J; Brewer, Thomas F; Chang, Christopher J R01ES028096 Curr Opin Chem Biol (2017 Aug) 28527906 Exiting the NIEHS site 2017 
Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism.   Burgos-Barragan, Guillermo; Wit, Niek; Meiser, Johannes; Dingler, Felix A; Pietzke, Matthias; M ... P42ES004705, R01ES028096 Nature (2017 08 31) 28813411 Exiting the NIEHS site 2017 
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