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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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One Carbon to Rule Them All: Formaldehyde is a One-Carbon Signal Connecting One-Carbon Metabolism an ... | Tenney, Logan; Pham, Vanha N; Chang, Christopher J | R01ES028096 | ACS Chem Biol (2024 Apr 19) | 38530767 | 2024 |
Oxidative cyclization reagents reveal tryptophan cation-π interactions. | Xie, Xiao; Moon, Patrick J; Crossley, Steven W M; Bischoff, Amanda J; He, Dan; Li, Gen; Dao, ... | R01ES028096 | Nature (2024 Mar) | 38448587 | 2024 |
Chemical Sensors and Imaging: Molecular, Materials, and Biological Platforms. | Messina, Marco S; Chang, Christopher J | R01ES028096 | ACS Cent Sci (2023 Sep 27) | 37780366 | 2023 |
Interface of biomolecular condensates modulates redox reactions. | Dai, Yifan; Chamberlayne, Christian F; Messina, Marco S; Chang, Christopher J; Zare, Richard N; ... | R01ES028096 | Chem (2023 Jun 08) | 37546704 | 2023 |
LOV thy neighbor: Mapping protein interactomes by genetically encodable photoproximity labeling. | Xie, Xiao; Jiang, Yishu; Chang, Christopher J | R01ES028096 | Proc Natl Acad Sci U S A (2023 May 16) | 37155840 | 2023 |
Metalloallostery and Transition Metal Signaling: Bioinorganic Copper Chemistry Beyond Active Sites. | Pham, Vanha N; Chang, Christopher J | R01ES028096 | Angew Chem Int Ed Engl (2023 Mar 06) | 36653724 | 2023 |
Neuroinflammation and white matter alterations in occupational manganese exposure assessed by diffus ... | Criswell, Susan R; Nielsen, Susan Searles; Faust, Irene M; Shimony, Joshua S; White 3rd, Robert ... | R01ES021488, R01ES029524 | Neurotoxicology (2023 Jul) | 37127223 | 2023 |
A puromycin-dependent activity-based sensing probe for histochemical staining of hydrogen peroxide i ... | Hoshi, Kaede; Messina, Marco S; Ohata, Jun; Chung, Clive Yik-Sham; Chang, Christopher J | R01ES028096 | Nat Protoc (2022 Jul) | 35562423 | 2022 |
Activity-Based Sensing for Chemistry-Enabled Biology: Illuminating Principles, Probes, and Prospects ... | Messina, Marco S; Quargnali, Gianluca; Chang, Christopher J | R01ES028096 | ACS Bio Med Chem Au (2022 Dec 21) | 36573097 | 2022 |
An Activity-Based Oxaziridine Platform for Identifying and Developing Covalent Ligands for Functiona ... | Gonzalez-Valero, Angel; Reeves, Audrey G; Page, Annika C S; Moon, Patrick J; Miller, Edward; Co ... | R01ES028096 | J Am Chem Soc (2022 Dec 21) | 36484997 | 2022 |
Clinical Features and Evolution of Blepharospasm: A Multicenter International Cohort and Systematic ... | Scorr, Laura M; Cho, Hyun Joo; Kilic-Berkmen, Gamze; McKay, J Lucas; Hallett, Mark; Klein, Chr ... | R01ES029524 | Dystonia (2022) | 36248010 | 2022 |
Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo. | Murphy, Michael P; Bayir, Hülya; Belousov, Vsevolod; Chang, Christopher J; Davies, Kelvin J A; ... | R01ES028096 | Nat Metab (2022 Jun) | 35760871 | 2022 |
Head tremor in cervical dystonia: Quantifying severity with computer vision. | Vu, Jeanne P; Cisneros, Elizabeth; Lee, Ha Yeon; Le, Linh; Chen, Qiyu; Guo, Xiaoyan A; Rouzbeh ... | R01ES029524 | J Neurol Sci (2022 Mar 15) | 35101766 | 2022 |
Protracted course progressive supranuclear palsy. | Couto, Blas; Martinez-Valbuena, Ivan; Lee, Seojin; Alfradique-Dunham, Isabel; Perrin, Richard J ... | R01ES029524 | Eur J Neurol (2022 Aug) | 35384155 | 2022 |
A microtubule-localizing activity-based sensing fluorescent probe for imaging hydrogen peroxide in l ... | Jia, Shang; Chang, Christopher J | R01ES028096 | Bioorg Med Chem Lett (2021 09 15) | 34245851 | 2021 |
A tandem activity-based sensing and labeling strategy enables imaging of transcellular hydrogen pero ... | Iwashita, Hidefumi; Castillo, Erika; Messina, Marco S; Swanson, Raymond A; Chang, Christopher J | P42ES004705, R01ES028096 | Proc Natl Acad Sci U S A (2021 03 02) | 33622793 | 2021 |
Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product func ... | Luo, Mai; Spradlin, Jessica N; Boike, Lydia; Tong, Bingqi; Brittain, Scott M; McKenna, Jeffrey ... | R01ES028096 | Cell Chem Biol (2021 04 15) | 33513350 | 2021 |
Depression and anxiety in a manganese-exposed community. | Racette, Brad A; Nelson, Gill; Dlamini, Wendy W; Hershey, Tamara; Prathibha, Pradeep; Turner, ... | P42ES023716, R01ES029524, R01ES029846, R25ES025503 | Neurotoxicology (2021 07) | 34087333 | 2021 |
Is Levodopa Response a Valid Indicator of Parkinson's Disease? | Martin, W R Wayne; Miles, Michael; Zhong, Qiaonan; Hartlein, Johanna; Racette, Brad A; Norris, ... | R01ES029524 | Mov Disord (2021 Apr) | 33253432 | 2021 |
Principal Component Analysis of Striatal and Extrastriatal D2 Dopamine Receptor Positron Emission To ... | Criswell, Susan R; Searles Nielsen, Susan; Dlamini, Wendy W; Warden, Mark N; Perlmutter, Joel S ... | R01ES021488, R01ES029524 | Toxicol Sci (2021 07 16) | 33881537 | 2021 |
Resting-State Functional Connectivity Predicts STN DBS Clinical Response. | Younce, John R; Campbell, Meghan C; Hershey, Tamara; Tanenbaum, Aaron B; Milchenko, Mikhail; Us ... | R01ES029524 | Mov Disord (2021 Mar) | 33211330 | 2021 |
[11C]dihydrotetrabenazine Positron Emission Tomography in Manganese-Exposed Workers. | Criswell, Susan R; Nielsen, Susan Searles; Warden, Mark N; Perlmutter, Joel S; Moerlein, Stephe ... | R01ES021488, R01ES025792, R01ES025792, R01ES029524 | J Occup Environ Med (2020 10) | 32472844 | 2020 |
A Surge of DNA Damage Links Transcriptional Reprogramming and Hematopoietic Deficit in Fanconi Anemi ... | Shen, Xi; Wang, Rui; Kim, Moon Jong; Hu, Qianghua; Hsu, Chih-Chao; Yao, Jun; Klages-Mundt, Na ... | P42ES004705, R01ES028096 | Mol Cell (2020 12 17) | 33338401 | 2020 |
Activity-Based Sensing: A Synthetic Methods Approach for Selective Molecular Imaging and Beyond. | Bruemmer, Kevin J; Crossley, Steven W M; Chang, Christopher J | P42ES004705, R01ES028096 | Angew Chem Int Ed Engl (2020 Aug 10) | 31605413 | 2020 |
Carbon Monoxide, a Retrograde Messenger Generated in Postsynaptic Mushroom Body Neurons, Evokes Nonc ... | Ueno, Kohei; Morstein, Johannes; Ofusa, Kyoko; Naganos, Shintaro; Suzuki-Sawano, Ema; Minegishi ... | P42ES004705, R01ES028096 | J Neurosci (2020 04 29) | 32253360 | 2020 |
Distinct RNA N-demethylation pathways catalyzed by nonheme iron ALKBH5 and FTO enzymes enable regula ... | Toh, Joel D W; Crossley, Steven W M; Bruemmer, Kevin J; Ge, Eva J; He, Dan; Iovan, Diana A; Ch ... | P42ES004705, R01ES028096 | Proc Natl Acad Sci U S A (2020 10 13) | 32989163 | 2020 |
Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem ... | Coles, Garry L; Cristea, Sandra; Webber, James T; Levin, Rebecca S; Moss, Steven M; He, Andy; ... | R01ES028096 | Cancer Cell (2020 07 13) | 32531271 | 2020 |
Activity-Based Sensing Methods for Monitoring the Reactive Carbon Species Carbon Monoxide and Formal ... | Ohata, Jun; Bruemmer, Kevin J; Chang, Christopher J | R01ES028096 | Acc Chem Res (2019 Oct 15) | 31487154 | 2019 |
Bioinspired Thiophosphorodichloridate Reagents for Chemoselective Histidine Bioconjugation. | Jia, Shang; He, Dan; Chang, Christopher J | P42ES004705, R01ES028096 | J Am Chem Soc (2019 05 08) | 31017395 | 2019 |
Caged luciferins for bioluminescent activity-based sensing. | Su, Timothy A; Bruemmer, Kevin J; Chang, Christopher J | P42ES004705, R01ES028096 | Curr Opin Biotechnol (2019 12) | 31200275 | 2019 |
Covalent targeting of the vacuolar H+-ATPase activates autophagy via mTORC1 inhibition. | Chung, Clive Yik-Sham; Shin, Hijai R; Berdan, Charles A; Ford, Breanna; Ward, Carl C; Olzmann, ... | P42ES004705, R01ES028096 | Nat Chem Biol (2019 Aug) | 31285595 | 2019 |
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation. | Spradlin, Jessica N; Hu, Xirui; Ward, Carl C; Brittain, Scott M; Jones, Michael D; Ou, Lisha; ... | P42ES004705, R01ES028096 | Nat Chem Biol (2019 07) | 31209351 | 2019 |
Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells. | Berdan, Charles A; Ho, Raymond; Lehtola, Haley S; To, Milton; Hu, Xirui; Huffman, Tucker R; Pe ... | P42ES004705, R01ES028096 | Cell Chem Biol (2019 07 18) | 31080076 | 2019 |
Chemiluminescent Probes for Activity-Based Sensing of Formaldehyde Released from Folate Degradation ... | Bruemmer, Kevin J; Green, Ori; Su, Timothy A; Shabat, Doron; Chang, Christopher J | R01ES028096 | Angew Chem Int Ed Engl (2018 06 18) | 29635731 | 2018 |
Chemoproteomics-Enabled Covalent Ligand Screening Reveals ALDH3A1 as a Lung Cancer Therapy Target. | Counihan, Jessica L; Wiggenhorn, Amanda L; Anderson, Kimberly E; Nomura, Daniel K | P42ES004705, R01ES028096 | ACS Chem Biol (2018 Aug 17) | 30004670 | 2018 |
A 2-aza-Cope reactivity-based platform for ratiometric fluorescence imaging of formaldehyde in livin ... | Brewer, Thomas F; Burgos-Barragan, Guillermo; Wit, Niek; Patel, Ketan J; Chang, Christopher J | R01ES028096 | Chem Sci (2017 May 01) | 28580121 | 2017 |
Covalent Ligand Discovery against Druggable Hotspots Targeted by Anti-cancer Natural Products. | Grossman, Elizabeth A; Ward, Carl C; Spradlin, Jessica N; Bateman, Leslie A; Huffman, Tucker R; ... | R01ES028096 | Cell Chem Biol (2017 Nov 16) | 28919038 | 2017 |
Development of a General Aza-Cope Reaction Trigger Applied to Fluorescence Imaging of Formaldehyde i ... | Bruemmer, Kevin J; Walvoord, Ryan R; Brewer, Thomas F; Burgos-Barragan, Guillermo; Wit, Niek; P ... | R01ES028096 | J Am Chem Soc (2017 04 19) | 28375637 | 2017 |
Fluorescent probes for imaging formaldehyde in biological systems. | Bruemmer, Kevin J; Brewer, Thomas F; Chang, Christopher J | R01ES028096 | Curr Opin Chem Biol (2017 Aug) | 28527906 | 2017 |
Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism. | Burgos-Barragan, Guillermo; Wit, Niek; Meiser, Johannes; Dingler, Felix A; Pietzke, Matthias; M ... | P42ES004705, R01ES028096 | Nature (2017 08 31) | 28813411 | 2017 |