Title: NRF2 Activates Growth Factor Genes and Downstream AKT Signaling to Induce Mouse and Human Hepatomegaly (RNA-seq dataset 2)

Accession Number: GSE144864

Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE144864

Repository: Gene Expression Omnibus (GEO)

Data Type(s): Gene Expression

Experiment Type(s): Expression profiling by high throughput sequencing

Organism(s): Mus musculus

Summary: The goal of this study is to provide the liver metabolic changes in the liver specific constitutively NRF2 activated (Nrf2Act-hep) mice. Overall design: RNAs were extracted from livers of 6 week-old Wild Type (WT) B6 and Nrf2Act-hep mice for RNA-seq analysis.

Publication(s) associated with this dataset:

• He F, Antonucci L, Yamachika S, Zhang Z, Taniguchi K, Umemura A, Hatzivassiliou G, Roose-Girma M, Reina-Campos M, Molina AD, Diaz-Meco MT, Moscat J, Sun B, Karin M. 2020. NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomegaly. J Hepatol 72:1182-1195. doi:10.1016/j.jhep.2020.01.023 PMID:32105670