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Your Environment. Your Health.

Person Details: David W. Threadgill

Superfund Research Program

David W. Threadgill

Texas A&M University
4467 TAMU
College Station, Texas 77843-4467
Phone: 979-862-2569
Email: dwthreadgill@tamu.edu

Projects

Publications

2023

  • Cuomo D, Nitcher M, Barba E, Feinberg AP, Rusyn I, Chiu WA, Threadgill DW. 2023. Refining risk estimates for lead in drinking water based on the impact of genetics and diet on blood lead levels using the Collaborative Cross mouse population. Toxicol Sci doi:10.1093/toxsci/kfad054 PMID:37243727 PMCID:PMC10375319

2022

  • Morgan AP, Hughes JJ, Didion JP, Jolley WJ, Campbell KJ, Threadgill DW, Banhomme F, Searle JB, Pardo-Manuel de Villena F. 2022. Population structure and inbreeding in wild house mice (Mus musculus) at different geographic scales. Heredity (Edinb) 129(3):183-194. doi:10.1038/s41437-022-00551-z PMID:35764696 PMCID:PMC9411160

2021

  • Warren M, Radulescu A, Dornbos P, Cuomo D, Zumwalt S, Bueso-Mendoza D, Nitcher M, LaPres JJ, Threadgill DW. 2021. Peanut butter as an alternative dose delivery method to prevent strain-dependent orogastric gavage-induced stress in mouse teratogenicity studies. J Pharmacol Toxicol Methods 107:106948. doi:10.1016/j.vascn.2020.106948 PMID:33387613

2020

  • Sigmon JS, Blanchard MW, Baric RS, Bell TA, Brennan J, Brockmann GA, Burks AW, Calabrese JM, Caron KM, Cheney RE, Ciavatta D, Conlon F, Darr DB, Faber J, Franklin C, Gershon TR, Gralinski L, Gu B, Gaines CH, Hagan RS, Heimsath EG, Heise MT, Hock P, Ideraabdullah FY, Jennette JC, Kafri T, Kashfeen A, Kulis M, Kumar V, Linnertz C, Livraghi-Butrico A, Lloyd KK, Lutz C, Lynch RM, Magnuson T, Matsushima GK, McMullan R, Miller DR, Mohlke KL, Moy SS, Murphy C, Najarian M, O'Brien L, Palmer AA, Philpot BD, Randell SH, Reinholdt L, Ren Y, Rockwood S, Rogala AR, Saraawatula A, Sassetti CM, Schisler JC, Schoenrock SA, Shaw GD, Shorter JR, Smith CM, St Pierre CL, Tarantino LM, Threadgill DW, Valdar W, Vilen BJ, Wardwell K, Whitmire JL, Williams L, Zylka MJ, Ferris MT, McMillan L, Pardo-Manuel de Villena F. 2020. Content and performance of the MiniMUGA genotyping array, a new tool to improve rigor and reproducibility in mouse research. Genetics 216:905-930. doi:10.1534/genetics.120.303596 PMID:33067325 PMCID:PMC7768238

2019

  • Lewis L, Borowa-Mazgaj B, de Conti A, Chappell G, Luo Y, Bodnar WM, Konganti K, Wright FA, Threadgill DW, Chiu WA, Pogribny IP, Rusyn I. 2019. Population-based analysis of DNA damage and epigenetic effects of 1,3-butadiene in the mouse. Chem Res Toxicol 32(5):doi:10.1021/acs.chemrestox.9b00035 PMID:30990016 (ahead of print)
  • Luo Y, Cichocki JA, Hsieh N, Lewis L, Wright FA, Threadgill DW, Chiu WA, Rusyn I. 2019. Using Collaborative Cross mouse population to fill data gaps in risk assessment: A case study of population-based analysis of toxicokinetics and kidney toxicodynamics of tetrachloroethylene. Environ Health Perspect 127(6):67011. doi:10.1289/EHP5105 PMID:31246107 PMCID:PMC6792382
  • Perry A, Lynch RM, Rusyn I, Threadgill DW. 2019. Long-term combinatorial exposure to trichloroethylene and inorganic arsenic in genetically heterogeneous mice results in renal tubular damage and cancer-associated molecular changes. G3 (Bethesda) 9(5):1729-1737. doi:10.1534/g3.119.400161 PMID:30898898 PMCID:PMC6505147
  • Wang P, Wang Y, Langley SA, Zhou Y, Jen K, Sun Q, Brislawn C, Rojas CM, Wahl KL, Wang T, Fan X, Jansson J, Celniker SE, Zou X, Threadgill DW, Snijders AM, Mao J. 2019. Diverse tumour susceptibility in Collaborative Cross mice: Identification of a new mouse model for human gastric tumourigenesis. Gut doi:10.1136/gutjnl-2018-316691 PMID:30842212

2018

  • Cichocki JA, Luo Y, Furuya S, Venkatratnam A, Konganti K, Chiu WA, Threadgill DW, Pogribny IP, Rusyn I. 2018. Modulation of Tetrachloroethylene-Associated Kidney Effects by Nonalcoholic Fatty Liver or Steatohepatitis in Male C57BL/6J Mice. Toxicol Sci 167(1):126-137. doi:10.1093/toxsci/kfy223 PMID:30202895 PMCID:PMC6317418
  • Cuomo D, Porreca I, Ceccarelli M, Threadgill DW, Barrington WT, Petriella A, D'Angelo F, Cobellis G, De Stefano F, D' Agostino MN, De Felice M, Mallardo M, Ambrosino C. 2018. Transcriptional landscape of mouse-aged ovaries reveals a unique set of non-coding RNAs associated with physiological and environmental ovarian dysfunctions. Cell Death Discov doi:10.1038/s41420-018-0121-y PMID:30534420
  • Dornbos P, Warren M, Crawford RB, Kaminski NE, Threadgill DW, LaPres JJ. 2018. Characterizing Serpinb2 as a modulator of TCDD-induced suppression of the B cell. Chem Res Toxicol 31(11):1248-1259. doi:10.1021/acs.chemrestox.8b00225 PMID:30339366 (ahead of print)
  • Garbutt TA, Konneker TI, Konganti K, Hillhouse AE, Swift-Haire F, Jones A, Phelps D, Aylor DL, Threadgill DW. 2018. Permissiveness to form pluripotent stem cells may be an evolutionarily derived characteristic in Mus musculus. Sci Rep 8(1):14706. doi:10.1038/s41598-018-32116-8 PMID:30279419 PMCID:PMC6168588
  • Venkatratnam A, House JS, Konganti K, McKenney C, Threadgill DW, Chiu WA, Aylor DL, Wright FA, Rusyn I. 2018. Population-based dose-response analysis of liver transcriptional response to trichloroethylene in mouse. Mamm Genome 29:168-181. doi:10.1007/s00335-018-9734-y PMID:29353386 PMCID:PMC6094947

2017

  • Cichocki JA, Furuya S, Konganti K, Luo Y, McDonald TJ, Iwata Y, Chiu WA, Threadgill DW, Pogribny IP, Rusyn I. 2017. Impact of nonalcoholic fatty liver disease on toxicokinetics of tetrachloroethylene in mice. J Pharmacol Exp Ther 361(1):17-28. doi:10.1124/jpet.116.238790 PMID:28148637 PMCID:PMC5363767
  • Cichocki JA, Furuya S, Venkatratnam A, McDonald TJ, Knap A, Wade TL, Sweet S, Chiu WA, Threadgill DW, Rusyn I. 2017. Characterization of variability in toxicokinetics and toxicodynamics of tetrachloroethylene using the collaborative cross mouse population. Environ Health Perspect 125(5):057006. doi:10.1289/ehp788 PMID:28572074 PMCID:PMC5726344
  • Venkatratnam A, Furuya S, Kosyk O, Gold A, Bodnar WM, Konganti K, Threadgill DW, Gillespie DA, Aylor DL, Wright FA, Chiu WA, Rusyn I. 2017. Editor's Highlight: Collaborative Cross mouse population enables refinements to characterization of the variability in toxicokinetics of trichloroethylene and provides genetic evidence for the role of PPAR pathway in its oxidative metabolism. Toxicol Sci 158(1):48-62. doi:10.1093/toxsci/kfx065 PMID:28369613

2011

2010

2009

  • DeSimone MC, Harbourt D, Boysen G, Collins LB, Waldyanatha S, Bradford BU, Threadgill DW, Rusyn I, Kim S. 2009. Analysis of trichloroethylene metabolism in a genetically diverse panel of mouse inbred strains. In: Society of Toxicology Annual Meeting. Baltimore, MD.
  • Gatti DM, Harrill AH, Wright FA, Threadgill DW, Rusyn I. 2009. Replication and narrowing of gene expression quantitative trait loci using inbred mice. Mamm Genome 20(7):437-446. doi:10.1007/s00335-009-9199-0 PMID:19609828 PMCID:PMC2745627
  • Hege A, Ross PK, Threadgill DW, Rusyn I. 2009. Phenotypic anchoring of gene expression data from acetaminophen hepatotoxicity studies in the mouse model of the human population reveals biomarkers of response. In: Society of Toxicology Annual Meeting. Baltimore, MD.

2006

  • DeSimone MC, Harbourt D, Boysen G, Collins LB, Bradford BU, Han J, Swenberg JA, Threadgill DW, Rusyn I. 2006. Multi-strain study of trichoroethylene toxicity in mice. In: Superfund Basic Research Program Annual Meeting, December 11-12. La Jolla, CA.
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