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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Person Details: Jing Zhang

Superfund Research Program

Jing Zhang

University of Washington
RM 303B, R&T Building
Harborview Medical Center
Seattle, Washington 98195
Phone: 206-897-5245
Fax: 206-897-5249
Email: zhangj@u.washington.edu

Projects

Publications

2015

  • Hoekstra JG, Cook TJ, Stewart T, Mattison HA, Dreisbach MT, Hoffer ZS, Zhang J. 2015. Astrocytic dynamin-like protein 1 regulates neuronal protection against excitotoxicity in Parkinson disease. Am J Pathol 185(2):536-549. doi:10.1016/j.ajpath.2014.10.022 PMID:25482923 PMCID:PMC4305181
  • Liu C, Cholerton B, Shi M, Ginghina C, Cain KC, Auinger P, Zhang J. 2015. CSF tau and tau/Aβ42 predict cognitive decline in Parkinson's disease. Parkinsonism Relat Disord 21(3):271-276. PMID:25596881
  • Nielsen SS, Checkoway H, Zhang J, Hofmann JN, Keifer M, Paulsen M, Farin FM, Cook TJ, Simpson C. 2015. Blood α-synuclein in agricultural pesticide handlers in central Washington State. Environ Res 136:75-81. doi:10.1016/j.envres.2014.10.014 PMID:25460623 PMCID:PMC4548290
  • Stewart T, Sossi V, Aasly JO, Wszolek ZK, Uitti RJ, Hasegawa K, Yokoyama T, Zabetian CP, Leverenz JB, Stoessi AJ, Wang Y, Ginghina C, Liu C, Cain KC, Auinger P, Kang U, Jensen PH, Shi M, Zhang J. 2015. Phosphorylated alpha-synuclein in Parkinson's disease: correlation depends on disease severity. Acta Neuropathol Commun 3:7. doi:10.1186/s40478-015-0185-3 PMID:25637461 PMCID:PMC4362824

2014

  • Gonzalez-Cuyar LF, Nelson G, Criswell SR, Ho P, Lonzanida JA, Checkoway H, Seixas N, Gelman BB, Evanoff BA, Murray J, Zhang J, Racette BA. 2014. Quantitative neuropathology associated with chronic manganese exposure in South African mine workers. Neurotoxicology 45:260-266. doi:10.1016/j.neuro.2013.12.008 PMID:24374477 PMCID:PMC4072755
  • Pan C, Zhou Y, Dator R, Ginghina C, Zhao Y, Movius J, Peskind ER, Zabetian CP, Quinn JF, Galasko D, Stewart T, Shi M, Zhang J. 2014. Targeted discovery and validation of plasma biomarkers of Parkinson's disease. J Proteome Res 13:4535-4545. doi:10.1021/pr500421v PMID:24853996 PMCID:PMC4224986
  • Shi M, Liu C, Cook TJ, Bullock KM, Zhao Y, Ginghina C, Li Y, Aro P, Dator R, He C, Hipp MJ, Zabetian CP, Peskind ER, Hu S, Quinn JF, Galasko D, Banks WA, Zhang J. 2014. Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson's disease. Acta Neuropathol 128(5):639-650. doi:10.1007/s00401-014-1314-y PMID:24997849 PMCID:PMC4201967
  • Stewart T, Sui Y, Gonzalez-Cuyar LF, Wong DT, Akin DM, Tumas V, Aasly JO, Ashmore E, Aro P, Ginghina C, Korff A, Zabetian CP, Leverenz JB, Shi M, Zhang J. 2014. Cheek cell-derived alpha-synuclein and DJ-1 do not differentiate Parkinson's disease from control. Neurobiol Aging 35(2):418-420. doi:10.1016/j.neurobiolaging.2013.08.008 PMID:24041968 PMCID:PMC3844543
  • Toledo JB, Korff A, Shaw LM, Trojanowski JQ, Zhang J, Alzheimer's Disease Neuroimaging Initiative. 2014. Low levels of cerebrospinal fluid complement 3 and factor H predict faster cognitive decline in mild cognitive impairment. Alzheimer's Research & Therapy 6:36. doi:10.1186/alzrt266 PMID:25478014 PMCID:PMC4255518

2013

2012

  • Aasly JO, Shi M, Sossi V, Stewart T, Johansen KK, Wszolek ZK, Uitti RJ, Hasegawa K, Yokoyama T, Zabetian CP, Kim H, Leverenz JB, Ginghina C, Armaly J, Edwards KL, Snapinn KW, Stoessl AJ, Zhang J. 2012. Cerebrospinal fluid amyloid beta and tau in LRRK2 mutation carriers. Neurology 78:55-61. doi:10.1212/WNL.0b013e31823ed101 PMID:22170881 PMCID:PMC3466497
  • Lin X, Cook TJ, Zabetian CP, Leverenz JB, Peskind ER, Hu S, Cain KC, Pan C, Edgar JS, Goodlett DR, Racette BA, Checkoway H, Montine TJ, Shi M, Zhang J. 2012. DJ-1 isoforms in whole blood as potential biomarkers of Parkinson disease. Sci Rep 2:doi:10.1038/srep00954 PMID:23233873 PMCID:PMC3518819
  • Mollenhauer B, Zhang J. 2012. Biochemical premotor biomarkers for Parkison's Disease. Movement Disorders 27:644-650. doi:10.1002/mds.24956 PMID:22508282 PMCID:PMC3428741
  • Racette BA, Criswell SR, Lundin JI, Hobson AJ, Seixas N, Kotzbauer PT, Evanoff BA, Perlmutter JS, Zhang J, Sheppard L, Checkoway H. 2012. Increased risk of Parkinsonism associated with welding exposure. Neurotoxicology 33(5):1356-1361. doi:10.1016/j.neuro.2012.08.011 PMID:22975422 PMCID:PMC3651999
  • Wang J, Hoekstra JG, Zuo C, Cook TJ, Zhang J. 2012. Biomarkers of Parkinson's disease: current status and future perspectives. Drug Discov Today 18(3-4):155-162. doi:10.1016/j.drudis.2012.09.001 PMID:22982303 PMCID:PMC3557745
  • Wang Y, Shi M, Chung KA, Zabetian CP, Leverenz JB, Berg D, Srulijes K, Trojanowski JQ, Lee VM, Siderowf AD, Hurtig H, Litvan I, Schiess MC, Peskind ER, Masuda M, Hasegawa M, Lin X, Pan C, Galasko D, Goldstein DS, Jensen PH, Yang H, Cain KC, Zhang J. 2012. Phosphorylated alpha-Synuclein in Parkinson's Disease. Sci Transl Med 4(121):121ra20. doi:10.1126/scitranslmed.3002566 PMID:22344688 PMCID:PMC3302662

2011

  • Shi M, Bradner J, Hancock AM, Chung KA, Quinn JF, Peskind ER, Galasko D, Jankovic J, Zabetian CP, Kim H, Leverenz JB, Montine TJ, Ginghina C, Kang U, Cain KC, Aasly JO, Goldstein DS, Zhang J, Wang Y. 2011. Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression. Ann Neurol 69(3):570-580. doi:10.1002/ana.22311 PMID:21400565 PMCID:PMC3117674
  • Shi M, Sui Y, Peskind ER, Li G, Hwang H, Devic I, Ginghina C, Edgar JS, Pan C, Goodlett DR, Furay AR, Gonzalez-Cuyar LF, Zhang J. 2011. Salivary Tau species are potential biomarkers of Alzheimer's disease. Journal of Alzheimers Disease 27(2):299-305. doi:10.3233/jad-2011-110731 PMID:21841250 PMCID:PMC3302350

2010

  • Caudle W, Bammler TK, Lin YS, Pan S, Zhang J. 2010. Using 'omics' to define pathogenesis and biomarkers of Parkinson's disease. Expert Rev Neurother 10(6):925-942. doi:10.1586/ern.10.54 PMID:20518609 PMCID:PMC2913169
  • Hong Z, Shi M, Chung KA, Quinn JF, Peskind ER, Galasko D, Jankovic J, Zabetian CP, Leverenz JB, Baird GS, Montine TJ, Hancock AM, Hwang H, Pan C, Bradner J, Kang U, Jensen PH, Zhang J. 2010. DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease. Brain 133(Pt3):713-726. doi:10.1093/brain/awq008 PMID:20157014 PMCID:PMC2842513
  • Hwang H, Zhang J, Chung KA, Leverenz JB, Zabetian CP, Peskind ER, Jankovic J, Su Z, Hancock AM, Pan C, Montine TJ, Pan S, Nutt J, Albin R, Gearing M, Beyer RP, Shi M, Zhang J. 2010. Glycoproteomics in neurodegenerative diseases. Mass Spectrom Rev 29(1):79-125. doi:10.1002/mas.20221 PMID:19358229 PMCID:PMC2799547
  • Liu J, Shi M, Hong Z, Zhang J, Bradner J, Quinn T, Beyer RP, McGeer PL, Chen S, Zhang J. 2010. Identification of ciliary neurotrophic factor receptor alpha as a mediator of neurotoxicity induced by alpha-synuclein. Proteomics 10(11):2138-2150. doi:10.1002/pmic.200900745 PMID:20340160 PMCID:PMC3013276
  • Mata IF, Shi M, Agarwal P, Chung KA, Edwards KL, Factor SA, Galasko D, Ginghina C, Griffith A, Higgins DS, Kay DM, Kim H, Leverenz JB, Quinn JF, Roberts JW, Samii A, Snapinn KW, Tsuang DW, Yearout D, Zhang J, Payami H. 2010. SNCA variant associated with Parkinson disease and plasma alpha-synuclein level. Arch Neurol 67(11):1350-1356. doi:10.1001/archneurol.2010.279 PMID:21060011 PMCID:PMC3010848
  • Montine TJ, Shi M, Quinn JF, Peskind ER, Craft S, Ginghina C, Chung KA, Kim H, Galasko D, Jankovic J, Zabetian CP, Leverenz JB, Zhang J. 2010. CSF AB42 and Tau in Parkinson's disease with cognitive impairment. Movement Disorders 25(15):2682-2685. doi:10.1002/mds.23287 PMID:20818673 PMCID:PMC2978754
  • Shi M, Zabetian CP, Hancock AM, Ginghina C, Hong Z, Yearout D, Chung KA, Quinn JF, Peskind ER, Galasko D, Jankovic J, Leverenz JB, Zhang J. 2010. Significance and confounders of peripheral DJ-1 and alpha-synuclein in Parkinson's disease. Neurosci Lett 480(1):78-82. doi:10.1016/j.neulet.2010.06.009 PMID:20540987 PMCID:PMC2943649

2009

2008

  • Shi M, Jinghua J, Wang Y, Beyer RP, Kitsou E, Albin R, Gearing M, Pan C, Zhang J. 2008. Mortalin: a protein associated with progression of Parkinson disease?. J Neuropathol Exp Neurol 67(2):117-124. doi:10.1097/nen.0b013e318163354a PMID:18219256
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