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National Institute of Environmental Health Sciences

 

Person Details

Superfund Research Program

Leena A. Nylander-French

University of North Carolina-Chapel Hill
Department of Environmental Sciences and Engineering
CB #7431, 159 Rosenau Hall
Chapel Hill, NC 27599-7431
Phone: 919-966-3826
Email:

Projects

Research Briefs

Publications

2012
  • Jiang, Rong, John E. French, V. Stober, J. Connie Kang-Sickel, F. Zou, and Leena A. Nylander-French. 2012. Single-Nucleotide Polymorphisms Associated with Skin Naphthyl-Keratin Adduct Levels in Workers Exposed to Naphthalene. Environmental Health Perspectives. 120:857-864. doi:10.1289/ehp.1104304  
2011
  • Kang-Sickel, J.Connie, Mary Ann Butler, Lynn Frame, Berrin Serdar, Yi-Chun E. Chao, Peter P. Egeghy, Stephen M. Rappaport, Christine A. Toennis, Wang Li, Tatyana Borisova, John E. French, and Leena A. Nylander-French. 2011. The utility of naphthyl-keratin adducts as biomarkers for jet-fuel exposure. Biomarkers.   16:590-599. doi:10.3109/1354750x.2011.611598  
2010
  • Kang-Sickel, J.Connie, V. Stober, John E. French, and Leena A. Nylander-French. 2010. Exposure to naphthalene induces naphthyl-keratin adducts in human epidermis in vitro and in vivo. Biomarkers.   15:488-497. doi:10.3109/1354750x.2010.485700  
2009
  • Kim, D. and Leena A. Nylander-French. 2009. Physiologically-Based Toxicokinetic Models and Their Application in Human Exposure and Internal Dose Assessment. In: Molecular, Clinical and Environmental Toxicology Volume 1. pp.470.
2008
  • Chao, Yi-Chun E., Lawrence L. Kupper, and Leena A. Nylander-French. 2008. Relative importance of predictors in multiple linear regression analysis for scientific studies. Journal of Occupational and Environmental Hygiene. 5(8):519-529. doi:10.1080/15459620802225481  
  • Chao, Yi-Chun E., Yue Zhao, Lawrence L. Kupper, and Leena A. Nylander-French. 2008. Quantifying the relative importance of predictors in multiple linear regression analyses for public health studies. Journal of Occupational and Environmental Hygiene. 5(8):519-529. doi:10.1080/15459620802225481  
  • Kang-Sickel, J.Connie, Tae-Gyu Nam, Karupiah Jayaraj, Louise M. Ball, John E. French, David G. Klapper, Avram Gold, and Leena A. Nylander-French. 2008. S-arylcysteine-keratin adducts as biomarkers of human dermal exposure to aromatic hydrocarbons. Chemical Research in Toxicology.   21(4):852-858.
  • Kim, David, Matthew W. Farthing, Cass T. Miller, and Leena A. Nylander-French. 2008. Mathematical description of the uptake of hydrocarbons in jet fuel across the Stratum Corneum of human volunteers. Toxicology Letters.   178(3):146-151. doi:10.1016/j.toxlet.2008.03.005  
2007
  • Kim, D., Melvin E. Andersen, Yi-Chun E. Chao, Peter P. Egeghy, Stephen M. Rappaport, and Leena A. Nylander-French. 2007. Human Dermal and Inhalation Exposures to Jet Fuel Can Be Predicted Using a PBTK Model. Environmental Health Perspectives. 115(6):894-901. doi:10.1289/ehp.9778  
  • Kim, David, Melvin E. Andersen, Yi-Chun E. Chao, Peter P. Egeghy, Stephen M. Rappaport, and Leena A. Nylander-French. 2007. PBTK modeling demonstrates contribution of dermal and inhalation exposure components to end-exhaled breath concentrations of naphthalene. Environmental Health Perspectives. 115:894-901.
  • Kim, David, Melvin E. Andersen, Yi-Chun E. Chao, Peter P. Egeghy, Stephen M. Rappaport, and Leena A. Nylander-French. 2007. Prediction of human dermal and inhalation exposures to jet fuel by analysis of a PBTK model. Environmental Health Perspectives. 115(6):894-901.
2006
  • Chao, Yi-Chun E., Lawrence L. Kupper, Berrin Serdar, Peter P. Egeghy, Stephen M. Rappaport, and Leena A. Nylander-French. 2006. Dermal exposure to jet fuel JP-8 significantly contributes to production of urinary naphthols in fuel-cell maintenance workers. Environmental Health Perspectives. 114(2):182-185. doi:10.1289/ehp.8288  
  • Kang-Sickel, J.Connie, Avram Gold, Louise M. Ball, Jayaraj Karupiah, Leena A. Nylander-French, Vandy Parron, David G. Klapper, and John E. French. 2006. Detection of naphthalene keratin adducts in human skin using ELISA. Drug Metabolism Reviews.   38(Suppl.2):67-68.
  • Kim, David, M. Anderson, and Leena A. Nylander-French. 2006. A dermatotoxicokinetic model of human exposures to jet fuel. Toxicological Sciences.   93(1):22-33.
  • Kim, David, M. Anderson, and Leena A. Nylander-French. 2006. Dermal absorption and penetration of jet fuel components in humans. Toxicology Letters.   165(1):11-21.
  • Serdar, Berrin, Rogelio Tornero-Velez, Diana Echeverria, Leena A. Nylander-French, Lawrence L. Kupper, and Stephen M. Rappaport. 2006. Predictors of occupational exposure to styrene and styrene-7,8-oxide in the reinforced plastics industry. Occupational and Environmental Medicine.   63(10):707-12.
2005
  • Chao, Yi-Chun E., Roger L. Gibson, and Leena A. Nylander-French. 2005. Dermal Exposure to Jet Fuel (JP-8) in US Air Force Personnel. Annals of Occupational Hygiene.   49(7):639-645.
2004
  • Chao, Yi-Chun E. and Leena A. Nylander-French. 2004. Determination of keratin protein in a tape-stripped skin sample from jet fuel exposed skin. Annals of Occupational Hygiene.   48(1):65-73.
  • Mattorano, Dino A., Lawrence L. Kupper, and Leena A. Nylander-French. 2004. Estimating dermal exposure to jet fuel (naphthalene) using adhesive tape strip samples. Annals of Occupational Hygiene.   48(2):139-146.
2003
  • Gold, Avram, Tae-Gyu Nam, Karupiah Jayaraj, Ramiah Sangaiah, David G. Klapper, Louise M. Ball, John E. French, and Leena A. Nylander-French. 2003. Synthesis of S-aryl-D,L-cysteines and incorporation into keratin sequences. Organic Preparations and Procedures International. 35(4):375-382.
2002
  • Egeghy, Peter P., Leena A. Nylander-French, Kristen K. Gwin, Irva Hertz-Picciotto, and Stephen M. Rappaport. 2002. Self-collected breath sampling for monitoring low-level benzene exposures among automobile mechanics. Annals of Occupational Hygiene.   46(5):489-500.
  • Nam, Tae-Gyu, Ramiah Sangaiah, Avram Gold, Gregory D. Lacks, Leena A. Nylander-French, and John E. French. 2002. Synthesis of FMOC-protected S-arylcysteines and modified keratin sequence peptides as specific epitopes as immunogens. Polycyclic Aromatic Compounds.   22(3-4):239-248.
2001
  • Nam, Tae-Gyu, Ramiah Sangaiah, Avram Gold, Gregory D. Lacks, Leena A. Nylander-French, and John E. French. 2001. Synthesis of FMOC-protected S-aryclysteines and modified keratin sequence peptides as specific epitopes as immunogens. In: Proceedings of the 18th International Symposiium on Polycyclic Aromatic Compounds, Sept 9-13. Cincinnati, OH.
  • Nylander-French, Leena A., Gregory D. Lacks, and Dino A. Mattorano. 2001. Quantification of naphthalene dermal exposure using non-invasive tape stripping of the stratum corneum, extraction, and normalization against keratin. Arbete och Halsa.   10:23-24.
2000
  • Nylander-French, Leena A. 2000. A tape-stripping method for measuring dermal exposure to multifunctional acrylates. Annals of Occupational Hygiene.   44:645-651.