Study Attribute | Value |
---|---|
CEBS Accession Number: | 002-02042-0014-0000-5 |
Chemical Name: | Diethylstilbestrol |
CASRN: | 56-53-1 |
NTP Study Type: | Genetic Toxicology - Micronucleus |
NTP Study ID: | A66561 |
Strain and Species: | Tg.AC Mouse |
Study Result: | Male: Negative; Female: Negative |
Blood
Start Date | Sample Collection Time | Sex | Cell | Methodology Used | Dosing Regimen | Route | Trend Test P-Value |
---|---|---|---|---|---|---|---|
2000-04-25 | 24 hour | Female | NCE | Slide Scoring | Gavage x 52, 26 week | Gavage | 0.156 |
Dose (ug/kg) | Number of Animals Scored | Mean MN-NCE/1000 NCE ± SEM | Pairwise P | ||||
---|---|---|---|---|---|---|---|
Vehicle Control | Corn Oil | 0 |
8 | 1.190 ± 0.350 | |||
Test Chemical | Diethylstilbestrol | 30 |
12 | 1.290 ± 0.210 | 0.386 | ||
240 |
11 | 0.770 ± 0.170 | 0.903 | ||||
480 |
8 | 1.750 ± 0.250 | 0.095 |
Blood
Start Date | Sample Collection Time | Sex | Cell | Methodology Used | Dosing Regimen | Route | Trend Test P-Value |
---|---|---|---|---|---|---|---|
2000-04-25 | 24 hour | Male | NCE | Slide Scoring | Gavage x 52, 26 week | Gavage | 0.237 |
Dose (ug/kg) | Number of Animals Scored | Mean MN-NCE/1000 NCE ± SEM | Pairwise P | ||||
---|---|---|---|---|---|---|---|
Vehicle Control | Corn Oil | 0 |
12 | 1.000 ± 0.190 | |||
Test Chemical | Diethylstilbestrol | 30 |
11 | 1.320 ± 0.250 | 0.158 | ||
240 |
13 | 0.730 ± 0.170 | 0.848 | ||||
480 |
12 | 1.420 ± 0.270 | 0.094 |