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Your Environment. Your Health.

Who We Fund: Publication Detail

Project Title: AH RECEPTOR DYSREGULATION ALTERS HEMATOPOIETIC STEM CELLS
PI: Lawrence, B Paige
Institution: University Of Rochester
Grant Number: R01ES004862

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 49 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/R01ES004862/format/excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
DNA Methylation Patterns in T Cells of Naïve and Influenza A Virus-Infected Mice Developmentally Ex ...   Burke, Catherine G; Myers, Jason R; Post, Christina M; Boulé, Lisbeth A; Lawrence, B Paige P30ES001247, R01ES004862, T32ES007026 Environ Health Perspect (2021 Jan) 33449811 Exiting the NIEHS site 2021 
Developmental exposure to chemicals associated with unconventional oil and gas extraction alters imm ...   Robert, Jacques; McGuire, Connor C; Nagel, Susan; Lawrence, B Paige; Andino, Francisco De Jesús P30ES001247, R01ES004862, T32ES007026 Sci Total Environ (2019 Jun 25) 30939317 Exiting the NIEHS site 2019 
Early life exposures shape the CD4+ T cell transcriptome, influencing proliferation, differentiation ...   Burke, Catherine G; Myers, Jason R; Boule, Lisbeth A; Post, Christina M; Brookes, Paul S; Lawre ... P30ES001247, R01ES004862, T32ES007026 Sci Rep (2019 08 07) 31391494 Exiting the NIEHS site 2019 
Genome-Wide Transcriptional Analysis Reveals Novel AhR Targets That Regulate Dendritic Cell Function ...   Franchini, Anthony M; Myers, Jason R; Jin, Guang-Bi; Shepherd, David M; Lawrence, B Paige P30ES001247, R01ES004862, T32ES007026 Immunohorizons (2019 06 17) 31356168 Exiting the NIEHS site 2019 
The Ancestral Environment Shapes Antiviral CD8+ T cell Responses across Generations.   Post, Christina M; Boule, Lisbeth A; Burke, Catherine G; O'Dell, Colleen T; Winans, Bethany; La ... R01ES004862, T32ES007026 iScience (2019 Oct 25) 31569050 Exiting the NIEHS site 2019 
Aryl hydrocarbon receptor signaling modulates antiviral immune responses: ligand metabolism rather t ...   Boule, Lisbeth A; Burke, Catherine G; Jin, Guang-Bi; Lawrence, B Paige P30ES001247, R01ES004862, T32ES007026 Sci Rep (2018 01 29) 29379138 Exiting the NIEHS site 2018 
Developmental Exposure to a Mixture of 23 Chemicals Associated With Unconventional Oil and Gas Opera ...   Boulé, Lisbeth A; Chapman, Timothy J; Hillman, Sara E; Kassotis, Christopher D; O'Dell, Colleen ... R01ES004862 Toxicol Sci (2018 06 01) 29718478 Exiting the NIEHS site 2018 
Environmental cues received during development shape dendritic cell responses later in life.   Meyers, Jessica L; Winans, Bethany; Kelsaw, Erin; Murthy, Aditi; Gerber, Scott; Lawrence, B Pa ... R01ES004862 PLoS One (2018) 30412605 Exiting the NIEHS site 2018 
Environmental exposures are hidden modifiers of anti-viral immunity.   Franchini, Anthony M; Lawrence, B Paige P30ES001247, R01ES004862, T32ES007026 Curr Opin Toxicol (2018 Aug) 30035244 Exiting the NIEHS site 2018 
Old Receptor, New Tricks-The Ever-Expanding Universe of Aryl Hydrocarbon Receptor Functions. Report ...   Esser, Charlotte; Lawrence, B Paige; Sherr, David H; Perdew, Gary H; Puga, Alvaro; Barouki, Ro ... R01ES004862, R35ES028244 Int J Mol Sci (2018 Nov 15) 30445691 Exiting the NIEHS site 2018 
Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cel ...   Yee, Min; Domm, William; Gelein, Robert; Bentley, Karen L de Mesy; Kottmann, R Matthew; Sime, ... P30ES001247, R01ES004862, T32ES007026 Am J Respir Cell Mol Biol (2017 04) 27967234 Exiting the NIEHS site 2017 
Long term effects of carbaryl exposure on antiviral immune responses in Xenopus laevis.   De Jesús Andino, Francisco; Lawrence, B Paige; Robert, Jacques P30ES001247, R01ES004862, T32ES007026 Chemosphere (2017 Mar) 27988452 Exiting the NIEHS site 2017 
Aryl Hydrocarbon Receptor Deficiency in an Exon 3 Deletion Mouse Model Promotes Hematopoietic Stem C ...   Unnisa, Zeenath; Singh, Kameshwar P; Henry, Ellen C; Donegan, Catherine L; Bennett, John A; Gas ... P30ES001247, R01ES004862, T32ES007026 Stem Cells Int (2016) 27366154 Exiting the NIEHS site 2016 
Deficiency in Aryl Hydrocarbon Receptor (AHR) Expression throughout Aging Alters Gene Expression Pro ...   Bennett, John A; Singh, Kameshwar P; Unnisa, Zeenath; Welle, Stephen L; Gasiewicz, Thomas A R01ES004862, T32ES007026 PLoS One (2015) 26208102 Exiting the NIEHS site 2015 
Loss of aryl hydrocarbon receptor promotes gene changes associated with premature hematopoietic stem ...   Singh, Kameshwar P; Bennett, John A; Casado, Fanny L; Walrath, Jason L; Welle, Stephen L; Gasie ... P30ES001247, R01ES004862, T32ES007026 Stem Cells Dev (2014 Jan 15) 24138668 Exiting the NIEHS site 2014 
Mode of action and dose-response framework analysis for receptor-mediated toxicity: The aryl hydroca ...   Budinsky, R A; Schrenk, D; Simon, T; Van den Berg, M; Reichard, J F; Silkworth, J B; Aylward, ... P30ES001247, R01ES004862 Crit Rev Toxicol (2014 Jan) 24245878 Exiting the NIEHS site 2014 
The Ah receptor in stem cell cycling, regulation, and quiescence.   Gasiewicz, Thomas A; Singh, Kameshwar P; Bennett, J Allen P30ES001247, R01ES004862, T32ES007026 Ann N Y Acad Sci (2014 Mar) 24495120 Exiting the NIEHS site 2014 
17ýý-Estradiol (E-2) administration to male (NZB ýý SWR)Fýýý mice results in increased Id(LN)Fýýý-re ...   Feng, F; Silvin, C J; Fiore, N C; Stoll, M L; Price, K E; Shanley, P S; Silverstone, A E; Gav ... R01ES004862 Lupus (2012 Mar) 22065096 Exiting the NIEHS site 2012 
Aryl hydrocarbon receptor activation in hematopoietic stem/progenitor cells alters cell function and ...   Casado, Fanny L; Singh, Kameshwar P; Gasiewicz, Thomas A P30ES001247, R01ES004862, T32ES007026 Mol Pharmacol (2011 Oct) 21791576 Exiting the NIEHS site 2011 
Identification of stage-specific gene modulation during early thymocyte development by whole-genome ...   Laiosa, Michael D; Mills, Jeffrey H; Lai, Zhi-Wei; Singh, Kameshwar P; Middleton, Frank A; Gasi ... P30ES001247, R01ES004862, T32ES007026 Mol Pharmacol (2010 May) 20159946 Exiting the NIEHS site 2010 
The aryl hydrocarbon receptor has an important role in the regulation of hematopoiesis: implications ...   Gasiewicz, Thomas A; Singh, Kameshwar P; Casado, Fanny L P30ES001247, R01ES004862, T32ES007026 Chem Biol Interact (2010 Mar 19) 19896476 Exiting the NIEHS site 2010 
The aryl hydrocarbon receptor: regulation of hematopoiesis and involvement in the progression of blo ...   Casado, Fanny L; Singh, Kameshwar P; Gasiewicz, Thomas A P30ES001247, R01ES004862, T32ES007026 Blood Cells Mol Dis (2010 Apr 15) 20171126 Exiting the NIEHS site 2010 
Estrogen signaling is not required for prostatic bud patterning or for its disruption by 2,3,7,8-tet ...   Allgeier, Sarah Hicks; Vezina, Chad M; Lin, Tien-Min; Moore, Robert W; Silverstone, Allen E; Mu ... R01ES001332, R01ES001332, R01ES004862, T32ES007015 Toxicol Appl Pharmacol (2009 Aug 15) 19523480 Exiting the NIEHS site 2009 
The aryl hydrocarbon receptor has a normal function in the regulation of hematopoietic and other ste ...   Singh, Kameshwar P; Casado, Fanny L; Opanashuk, Lisa A; Gasiewicz, Thomas A P30ES001247, R01ES004862, T32ES007026 Biochem Pharmacol (2009 Feb 15) 18983985 Exiting the NIEHS site 2009 
Treatment of mice with the Ah receptor agonist and human carcinogen dioxin results in altered number ...   Singh, Kameshwar P; Wyman, Amber; Casado, Fanny L; Garrett, Russell W; Gasiewicz, Thomas A P30ES001247, R01ES004862, T32ES007026 Carcinogenesis (2009 Jan) 18820284 Exiting the NIEHS site 2009 
Expression and activity of aryl hydrocarbon receptors in development and cancer.   Gasiewicz, Thomas A; Henry, Ellen C; Collins, Loretta L P30ES001247, R01ES004862 Crit Rev Eukaryot Gene Expr (2008) 18652561 Exiting the NIEHS site 2008 
The aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin alters the circadian rhyth ...   Garrett, Russell W; Gasiewicz, Thomas A P30ES001247, R01ES004862, T32ES007026 Mol Pharmacol (2006 Jun) 16556773 Exiting the NIEHS site 2006 
Cell proliferation arrest within intrathymic lymphocyte progenitor cells causes thymic atrophy media ...   Laiosa, Michael D; Wyman, Amber; Murante, Francis G; Fiore, Nancy C; Staples, J Erin; Gasiewicz ... P30ES001247, R01ES004862, T32ES007026 J Immunol (2003 Nov 01) 14568932 Exiting the NIEHS site 2003 
2,3,7,8-tetrachlorodibenzo-p-dioxin causes alterations in lymphocyte development and thymic atrophy ...   Laiosa, Michael D; Lai, Zhi-Wei; Thurmond, T Scott; Fiore, Nancy C; DeRossi, Charles; Holdener, ... P30ES001247, R01ES004862 Toxicol Sci (2002 Sep) 12215665 Exiting the NIEHS site 2002 
2,3,7,8-tetrachlorodibenzo-p-dioxin does not directly alter the phenotype of maturing B cells in a m ...   Wyman, Amber; Lavin, Amy L; Wilding, Gregory E; Gasiewicz, Thomas A P30ES001247, R01ES004862, T32ES007026 Toxicol Appl Pharmacol (2002 May 1) 12009856 Exiting the NIEHS site 2002 
Aryl hydrocarbon receptor signaling plays a significant role in mediating benzo[a]pyrene- and cigare ...   Dertinger, S D; Nazarenko, D A; Silverstone, A E; Gasiewicz, T A R01ES004862 Carcinogenesis (2001 Jan) 11159756 Exiting the NIEHS site 2001 
A single dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin produces a time- and dose-dependent alteration ...   Thurmond, T S; Gasiewicz, T A P30ES001247, R01ES004862 Toxicol Sci (2000 Nov) 11053544 Exiting the NIEHS site 2000 
Differential effects of diethylstilbestrol and 2,3,7,8-tetrachlorodibenzo-p-dioxin on thymocyte diff ...   Lai, Z W; Fiore, N C; Hahn, P J; Gasiewicz, T A; Silverstone, A E P30ES001247, R01ES004862 Toxicol Appl Pharmacol (2000 Oct 1) 11000096 Exiting the NIEHS site 2000 
Effect of 3'-methoxy-4'-nitroflavone on benzo[a]pyrene toxicity. Aryl hydrocarbon receptor-dependent ...   Dertinger, S D; Lantum, H B; Silverstone, A E; Gasiewicz, T A R01ES004862 Biochem Pharmacol (2000 Jul 15) 10825463 Exiting the NIEHS site 2000 
Hemopoietic progenitor cells are sensitive targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin in C57BL/6 ...   Murante, F G; Gasiewicz, T A P30ES001247, R01ES004862, T32ES007026 Toxicol Sci (2000 Apr) 10774819 Exiting the NIEHS site 2000 
Role of estrogen receptor alpha in hematopoietic stem cell development and B lymphocyte maturation i ...   Thurmond, T S; Murante, F G; Staples, J E; Silverstone, A E; Korach, K S; Gasiewicz, T A R01ES004862, T32ES007026 Endocrinology (2000 Jul) 10875230 Exiting the NIEHS site 2000 
The aryl hydrocarbon receptor has a role in the in vivo maturation of murine bone marrow B lymphocyt ...   Thurmond, T S; Staples, J E; Silverstone, A E; Gasiewicz, T A R01ES004862 Toxicol Appl Pharmacol (2000 Jun 15) 10860871 Exiting the NIEHS site 2000 
A chimeric aryl hydrocarbon receptor knockout mouse model indicates that aryl hydrocarbon receptor a ...   Thurmond, T S; Silverstone, A E; Baggs, R B; Quimby, F W; Staples, J E; Gasiewicz, T A R01ES004862 Toxicol Appl Pharmacol (1999 Jul 1) 10387930 Exiting the NIEHS site 1999 
Estrogen receptor alpha is necessary in thymic development and estradiol-induced thymic alterations.   Staples, J E; Gasiewicz, T A; Fiore, N C; Lubahn, D B; Korach, K S; Silverstone, A E P30ES001247, R01ES004862 J Immunol (1999 Oct 15) 10510352 Exiting the NIEHS site 1999 
2,3,7,8-Tetrachlorodibenzo-p-dioxin and diethylstilbestrol affect thymocytes at different stages of ...   Lai, Z W; Fiore, N C; Gasiewicz, T A; Silverstone, A E P30ES001247, R01ES004862 Toxicol Appl Pharmacol (1998 Apr) 9571985 Exiting the NIEHS site 1998 
Aryl hydrocarbon receptor activation in genital tubercle, palate, and other embryonic tissues in 2,3 ...   Willey, J J; Stripp, B R; Baggs, R B; Gasiewicz, T A P30ES001247, R01ES004862 Toxicol Appl Pharmacol (1998 Jul) 9705885 Exiting the NIEHS site 1998 
Expression of functional aromatic hydrocarbon receptor and aromatic hydrocarbon nuclear translocator ...   Lavin, A L; Hahn, D J; Gasiewicz, T A P30ES001247, R01ES004862 Arch Biochem Biophys (1998 Apr 1) 9521805 Exiting the NIEHS site 1998 
Influence of aromatic hydrocarbon receptor-mediated events on the genotoxicity of cigarette smoke co ...   Dertinger, S D; Silverstone, A E; Gasiewicz, T A P30ES001247, R01ES004862, T32ES007026 Carcinogenesis (1998 Nov) 9855021 Exiting the NIEHS site 1998 
Overexpression of the anti-apoptotic oncogene, bcl-2, in the thymus does not prevent thymic atrophy ...   Staples, J E; Fiore, N C; Frazier Jr, D E; Gasiewicz, T A; Silverstone, A E P30ES001247, R01ES004862 Toxicol Appl Pharmacol (1998 Jul) 9705904 Exiting the NIEHS site 1998 
Thymic alterations induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin are strictly dependent on aryl hyd ...   Staples, J E; Murante, F G; Fiore, N C; Gasiewicz, T A; Silverstone, A E P30ES001247, R01ES004862 J Immunol (1998 Apr 15) 9558089 Exiting the NIEHS site 1998 
2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced thymic atrophy and lymphocyte stem cell alterations by m ...   Frazier Jr, D E; Silverstone, A E; Gasiewicz, T A P30ES001247, R01ES004862, T32ES007026 Biochem Pharmacol (1994 Jun 01) 8010988 Exiting the NIEHS site 1994 
Alternate immune system targets for TCDD: lymphocyte stem cells and extrathymic T-cell development.   Silverstone, A E; Frazier Jr, D E; Gasiewicz, T A R01ES004862, T32ES007026 Exp Clin Immunogenet (1994) 7826670 Exiting the NIEHS site 1994 
Dexamethasone, beta-estradiol, and 2,3,7,8-tetrachlorodibenzo-p-dioxin elicit thymic atrophy through ...   Silverstone, A E; Frazier Jr, D E; Fiore, N C; Soults, J A; Gasiewicz, T A P30ES001247, R01ES004862, T32ES007026 Toxicol Appl Pharmacol (1994 Jun) 7516097 Exiting the NIEHS site 1994 
The thymus does not mediate 2,3,7,8-tetrachlorodibenzo-p-dioxin-elicited alterations in bone marrow ...   Frazier Jr, D E; Silverstone, A E; Soults, J A; Gasiewicz, T A P30ES001247, R01ES004862, T32ES007026 Toxicol Appl Pharmacol (1994 Feb) 8122269 Exiting the NIEHS site 1994 
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