| Project Title: | AH RECEPTOR DYSREGULATION ALTERS HEMATOPOIETIC STEM CELLS |
|---|---|
| PI: | Lawrence, B Paige |
| Institution: | University Of Rochester |
| Grant Number: | R01ES004862 |
These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| DNA Methylation Patterns in T Cells of Naïve and Influenza A Virus-Infected Mice Developmentally Ex ... | Burke, Catherine G; Myers, Jason R; Post, Christina M; Boulé, Lisbeth A; Lawrence, B Paige | P30ES001247, R01ES004862, T32ES007026 | Environ Health Perspect (2021 Jan) |
33449811
|
2021 |
| Developmental exposure to chemicals associated with unconventional oil and gas extraction alters imm ... | Robert, Jacques; McGuire, Connor C; Nagel, Susan; Lawrence, B Paige; Andino, Francisco De Jesús | P30ES001247, R01ES004862, T32ES007026 | Sci Total Environ (2019 Jun 25) |
30939317
|
2019 |
| Early life exposures shape the CD4+ T cell transcriptome, influencing proliferation, differentiation ... | Burke, Catherine G; Myers, Jason R; Boule, Lisbeth A; Post, Christina M; Brookes, Paul S; Lawre ... | P30ES001247, R01ES004862, T32ES007026 | Sci Rep (2019 08 07) |
31391494
|
2019 |
| Genome-Wide Transcriptional Analysis Reveals Novel AhR Targets That Regulate Dendritic Cell Function ... | Franchini, Anthony M; Myers, Jason R; Jin, Guang-Bi; Shepherd, David M; Lawrence, B Paige | P30ES001247, R01ES004862, T32ES007026 | Immunohorizons (2019 06 17) |
31356168
|
2019 |
| The Ancestral Environment Shapes Antiviral CD8+ T cell Responses across Generations. | Post, Christina M; Boule, Lisbeth A; Burke, Catherine G; O'Dell, Colleen T; Winans, Bethany; La ... | R01ES004862, T32ES007026 | iScience (2019 Oct 25) |
31569050
|
2019 |
| Aryl hydrocarbon receptor signaling modulates antiviral immune responses: ligand metabolism rather t ... | Boule, Lisbeth A; Burke, Catherine G; Jin, Guang-Bi; Lawrence, B Paige | P30ES001247, R01ES004862, T32ES007026 | Sci Rep (2018 01 29) |
29379138
|
2018 |
| Developmental Exposure to a Mixture of 23 Chemicals Associated With Unconventional Oil and Gas Opera ... | Boulé, Lisbeth A; Chapman, Timothy J; Hillman, Sara E; Kassotis, Christopher D; O'Dell, Colleen ... | R01ES004862 | Toxicol Sci (2018 06 01) |
29718478
|
2018 |
| Environmental cues received during development shape dendritic cell responses later in life. | Meyers, Jessica L; Winans, Bethany; Kelsaw, Erin; Murthy, Aditi; Gerber, Scott; Lawrence, B Pa ... | R01ES004862 | PLoS One (2018) |
30412605
|
2018 |
| Environmental exposures are hidden modifiers of anti-viral immunity. | Franchini, Anthony M; Lawrence, B Paige | P30ES001247, R01ES004862, T32ES007026 | Curr Opin Toxicol (2018 Aug) |
30035244
|
2018 |
| Old Receptor, New Tricks-The Ever-Expanding Universe of Aryl Hydrocarbon Receptor Functions. Report ... | Esser, Charlotte; Lawrence, B Paige; Sherr, David H; Perdew, Gary H; Puga, Alvaro; Barouki, Ro ... | R01ES004862, R35ES028244 | Int J Mol Sci (2018 Nov 15) |
30445691
|
2018 |
| Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cel ... | Yee, Min; Domm, William; Gelein, Robert; Bentley, Karen L de Mesy; Kottmann, R Matthew; Sime, ... | P30ES001247, R01ES004862, T32ES007026 | Am J Respir Cell Mol Biol (2017 04) |
27967234
|
2017 |
| Long term effects of carbaryl exposure on antiviral immune responses in Xenopus laevis. | De Jesús Andino, Francisco; Lawrence, B Paige; Robert, Jacques | P30ES001247, R01ES004862, T32ES007026 | Chemosphere (2017 Mar) |
27988452
|
2017 |
| Aryl Hydrocarbon Receptor Deficiency in an Exon 3 Deletion Mouse Model Promotes Hematopoietic Stem C ... | Unnisa, Zeenath; Singh, Kameshwar P; Henry, Ellen C; Donegan, Catherine L; Bennett, John A; Gas ... | P30ES001247, R01ES004862, T32ES007026 | Stem Cells Int (2016) |
27366154
|
2016 |
| Deficiency in Aryl Hydrocarbon Receptor (AHR) Expression throughout Aging Alters Gene Expression Pro ... | Bennett, John A; Singh, Kameshwar P; Unnisa, Zeenath; Welle, Stephen L; Gasiewicz, Thomas A | R01ES004862, T32ES007026 | PLoS One (2015) |
26208102
|
2015 |
| Loss of aryl hydrocarbon receptor promotes gene changes associated with premature hematopoietic stem ... | Singh, Kameshwar P; Bennett, John A; Casado, Fanny L; Walrath, Jason L; Welle, Stephen L; Gasie ... | P30ES001247, R01ES004862, T32ES007026 | Stem Cells Dev (2014 Jan 15) |
24138668
|
2014 |
| Mode of action and dose-response framework analysis for receptor-mediated toxicity: The aryl hydroca ... | Budinsky, R A; Schrenk, D; Simon, T; Van den Berg, M; Reichard, J F; Silkworth, J B; Aylward, ... | P30ES001247, R01ES004862 | Crit Rev Toxicol (2014 Jan) |
24245878
|
2014 |
| The Ah receptor in stem cell cycling, regulation, and quiescence. | Gasiewicz, Thomas A; Singh, Kameshwar P; Bennett, J Allen | P30ES001247, R01ES004862, T32ES007026 | Ann N Y Acad Sci (2014 Mar) |
24495120
|
2014 |
| 17ýý-Estradiol (E-2) administration to male (NZB ýý SWR)Fýýý mice results in increased Id(LN)Fýýý-re ... | Feng, F; Silvin, C J; Fiore, N C; Stoll, M L; Price, K E; Shanley, P S; Silverstone, A E; Gav ... | R01ES004862 | Lupus (2012 Mar) |
22065096
|
2012 |
| Aryl hydrocarbon receptor activation in hematopoietic stem/progenitor cells alters cell function and ... | Casado, Fanny L; Singh, Kameshwar P; Gasiewicz, Thomas A | P30ES001247, R01ES004862, T32ES007026 | Mol Pharmacol (2011 Oct) |
21791576
|
2011 |
| Identification of stage-specific gene modulation during early thymocyte development by whole-genome ... | Laiosa, Michael D; Mills, Jeffrey H; Lai, Zhi-Wei; Singh, Kameshwar P; Middleton, Frank A; Gasi ... | P30ES001247, R01ES004862, T32ES007026 | Mol Pharmacol (2010 May) |
20159946
|
2010 |
| The aryl hydrocarbon receptor has an important role in the regulation of hematopoiesis: implications ... | Gasiewicz, Thomas A; Singh, Kameshwar P; Casado, Fanny L | P30ES001247, R01ES004862, T32ES007026 | Chem Biol Interact (2010 Mar 19) |
19896476
|
2010 |
| The aryl hydrocarbon receptor: regulation of hematopoiesis and involvement in the progression of blo ... | Casado, Fanny L; Singh, Kameshwar P; Gasiewicz, Thomas A | P30ES001247, R01ES004862, T32ES007026 | Blood Cells Mol Dis (2010 Apr 15) |
20171126
|
2010 |
| Estrogen signaling is not required for prostatic bud patterning or for its disruption by 2,3,7,8-tet ... | Allgeier, Sarah Hicks; Vezina, Chad M; Lin, Tien-Min; Moore, Robert W; Silverstone, Allen E; Mu ... | R01ES001332, R01ES001332, R01ES004862, T32ES007015 | Toxicol Appl Pharmacol (2009 Aug 15) |
19523480
|
2009 |
| The aryl hydrocarbon receptor has a normal function in the regulation of hematopoietic and other ste ... | Singh, Kameshwar P; Casado, Fanny L; Opanashuk, Lisa A; Gasiewicz, Thomas A | P30ES001247, R01ES004862, T32ES007026 | Biochem Pharmacol (2009 Feb 15) |
18983985
|
2009 |
| Treatment of mice with the Ah receptor agonist and human carcinogen dioxin results in altered number ... | Singh, Kameshwar P; Wyman, Amber; Casado, Fanny L; Garrett, Russell W; Gasiewicz, Thomas A | P30ES001247, R01ES004862, T32ES007026 | Carcinogenesis (2009 Jan) |
18820284
|
2009 |
| Expression and activity of aryl hydrocarbon receptors in development and cancer. | Gasiewicz, Thomas A; Henry, Ellen C; Collins, Loretta L | P30ES001247, R01ES004862 | Crit Rev Eukaryot Gene Expr (2008) |
18652561
|
2008 |
| The aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin alters the circadian rhyth ... | Garrett, Russell W; Gasiewicz, Thomas A | P30ES001247, R01ES004862, T32ES007026 | Mol Pharmacol (2006 Jun) |
16556773
|
2006 |
| Cell proliferation arrest within intrathymic lymphocyte progenitor cells causes thymic atrophy media ... | Laiosa, Michael D; Wyman, Amber; Murante, Francis G; Fiore, Nancy C; Staples, J Erin; Gasiewicz ... | P30ES001247, R01ES004862, T32ES007026 | J Immunol (2003 Nov 01) |
14568932
|
2003 |
| 2,3,7,8-tetrachlorodibenzo-p-dioxin causes alterations in lymphocyte development and thymic atrophy ... | Laiosa, Michael D; Lai, Zhi-Wei; Thurmond, T Scott; Fiore, Nancy C; DeRossi, Charles; Holdener, ... | P30ES001247, R01ES004862 | Toxicol Sci (2002 Sep) |
12215665
|
2002 |
| 2,3,7,8-tetrachlorodibenzo-p-dioxin does not directly alter the phenotype of maturing B cells in a m ... | Wyman, Amber; Lavin, Amy L; Wilding, Gregory E; Gasiewicz, Thomas A | P30ES001247, R01ES004862, T32ES007026 | Toxicol Appl Pharmacol (2002 May 1) |
12009856
|
2002 |
| Aryl hydrocarbon receptor signaling plays a significant role in mediating benzo[a]pyrene- and cigare ... | Dertinger, S D; Nazarenko, D A; Silverstone, A E; Gasiewicz, T A | R01ES004862 | Carcinogenesis (2001 Jan) |
11159756
|
2001 |
| A single dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin produces a time- and dose-dependent alteration ... | Thurmond, T S; Gasiewicz, T A | P30ES001247, R01ES004862 | Toxicol Sci (2000 Nov) |
11053544
|
2000 |
| Differential effects of diethylstilbestrol and 2,3,7,8-tetrachlorodibenzo-p-dioxin on thymocyte diff ... | Lai, Z W; Fiore, N C; Hahn, P J; Gasiewicz, T A; Silverstone, A E | P30ES001247, R01ES004862 | Toxicol Appl Pharmacol (2000 Oct 1) |
11000096
|
2000 |
| Effect of 3'-methoxy-4'-nitroflavone on benzo[a]pyrene toxicity. Aryl hydrocarbon receptor-dependent ... | Dertinger, S D; Lantum, H B; Silverstone, A E; Gasiewicz, T A | R01ES004862 | Biochem Pharmacol (2000 Jul 15) |
10825463
|
2000 |
| Hemopoietic progenitor cells are sensitive targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin in C57BL/6 ... | Murante, F G; Gasiewicz, T A | P30ES001247, R01ES004862, T32ES007026 | Toxicol Sci (2000 Apr) |
10774819
|
2000 |
| Role of estrogen receptor alpha in hematopoietic stem cell development and B lymphocyte maturation i ... | Thurmond, T S; Murante, F G; Staples, J E; Silverstone, A E; Korach, K S; Gasiewicz, T A | R01ES004862, T32ES007026 | Endocrinology (2000 Jul) |
10875230
|
2000 |
| The aryl hydrocarbon receptor has a role in the in vivo maturation of murine bone marrow B lymphocyt ... | Thurmond, T S; Staples, J E; Silverstone, A E; Gasiewicz, T A | R01ES004862 | Toxicol Appl Pharmacol (2000 Jun 15) |
10860871
|
2000 |
| A chimeric aryl hydrocarbon receptor knockout mouse model indicates that aryl hydrocarbon receptor a ... | Thurmond, T S; Silverstone, A E; Baggs, R B; Quimby, F W; Staples, J E; Gasiewicz, T A | R01ES004862 | Toxicol Appl Pharmacol (1999 Jul 1) |
10387930
|
1999 |
| Estrogen receptor alpha is necessary in thymic development and estradiol-induced thymic alterations. | Staples, J E; Gasiewicz, T A; Fiore, N C; Lubahn, D B; Korach, K S; Silverstone, A E | P30ES001247, R01ES004862 | J Immunol (1999 Oct 15) |
10510352
|
1999 |
| 2,3,7,8-Tetrachlorodibenzo-p-dioxin and diethylstilbestrol affect thymocytes at different stages of ... | Lai, Z W; Fiore, N C; Gasiewicz, T A; Silverstone, A E | P30ES001247, R01ES004862 | Toxicol Appl Pharmacol (1998 Apr) |
9571985
|
1998 |
| Aryl hydrocarbon receptor activation in genital tubercle, palate, and other embryonic tissues in 2,3 ... | Willey, J J; Stripp, B R; Baggs, R B; Gasiewicz, T A | P30ES001247, R01ES004862 | Toxicol Appl Pharmacol (1998 Jul) |
9705885
|
1998 |
| Expression of functional aromatic hydrocarbon receptor and aromatic hydrocarbon nuclear translocator ... | Lavin, A L; Hahn, D J; Gasiewicz, T A | P30ES001247, R01ES004862 | Arch Biochem Biophys (1998 Apr 1) |
9521805
|
1998 |
| Influence of aromatic hydrocarbon receptor-mediated events on the genotoxicity of cigarette smoke co ... | Dertinger, S D; Silverstone, A E; Gasiewicz, T A | P30ES001247, R01ES004862, T32ES007026 | Carcinogenesis (1998 Nov) |
9855021
|
1998 |
| Overexpression of the anti-apoptotic oncogene, bcl-2, in the thymus does not prevent thymic atrophy ... | Staples, J E; Fiore, N C; Frazier Jr, D E; Gasiewicz, T A; Silverstone, A E | P30ES001247, R01ES004862 | Toxicol Appl Pharmacol (1998 Jul) |
9705904
|
1998 |
| Thymic alterations induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin are strictly dependent on aryl hyd ... | Staples, J E; Murante, F G; Fiore, N C; Gasiewicz, T A; Silverstone, A E | P30ES001247, R01ES004862 | J Immunol (1998 Apr 15) |
9558089
|
1998 |
| 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced thymic atrophy and lymphocyte stem cell alterations by m ... | Frazier Jr, D E; Silverstone, A E; Gasiewicz, T A | P30ES001247, R01ES004862, T32ES007026 | Biochem Pharmacol (1994 Jun 01) |
8010988
|
1994 |
| Alternate immune system targets for TCDD: lymphocyte stem cells and extrathymic T-cell development. | Silverstone, A E; Frazier Jr, D E; Gasiewicz, T A | R01ES004862, T32ES007026 | Exp Clin Immunogenet (1994) |
7826670
|
1994 |
| Dexamethasone, beta-estradiol, and 2,3,7,8-tetrachlorodibenzo-p-dioxin elicit thymic atrophy through ... | Silverstone, A E; Frazier Jr, D E; Fiore, N C; Soults, J A; Gasiewicz, T A | P30ES001247, R01ES004862, T32ES007026 | Toxicol Appl Pharmacol (1994 Jun) |
7516097
|
1994 |
| The thymus does not mediate 2,3,7,8-tetrachlorodibenzo-p-dioxin-elicited alterations in bone marrow ... | Frazier Jr, D E; Silverstone, A E; Soults, J A; Gasiewicz, T A | P30ES001247, R01ES004862, T32ES007026 | Toxicol Appl Pharmacol (1994 Feb) |
8122269
|
1994 |