Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Internet Explorer is no longer a supported browser.

This website may not display properly with Internet Explorer. For the best experience, please use a more recent browser such as the latest versions of Google Chrome, Microsoft Edge, and/or Mozilla Firefox. Thank you.

Your Environment. Your Health.

Who We Fund: Publication Detail

Project Title: NEUROINFLAMMATION AND DEVELOPMENTAL VULNERABILITY TO MANGANESE TOXICITY
PI: Tjalkens, Ronald
Institution: Colorado State University
Grant Number: R01ES021656

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 25 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/R01ES021656/format/excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Nuclear receptor 4A2 (NR4A2) is a druggable target for glioblastomas.   Karki, Keshav; Li, Xi; Jin, Un-Ho; Mohankumar, Kumaravel; Zarei, Mahsa; Michelhaugh, Sharon K; ... P30ES029067, R01ES021656, R01ES025713, T32ES026568 J Neurooncol (2020 Jan) 31754919 Exiting the NIEHS site 2020 
Experimental Zika virus infection of Jamaican fruit bats (Artibeus jamaicensis) and possible entry o ...   Malmlov, Ashley; Bantle, Collin; Aboellail, Tawfik; Wagner, Kaitlyn; Campbell, Corey L; Eckley, ... R01ES021656 PLoS Negl Trop Dis (2019 02) 30716104 Exiting the NIEHS site 2019 
Genetic suppression of IKK2/NF-κB in astrocytes inhibits neuroinflammation and reduces neuronal loss ...   Kirkley, Kelly S; Popichak, Katriana A; Hammond, Sean L; Davies, Cecilia; Hunt, Lindsay; Tjalke ... R01ES021656 Neurobiol Dis (2019 07) 30818064 Exiting the NIEHS site 2019 
Structure-dependent activation of gene expression by bis-indole and quinoline-derived activators of ...   Li, Xi; Tjalkens, Ronald B; Shrestha, Rupesh; Safe, Stephen P30ES029067, R01ES021656, T32ES026568 Chem Biol Drug Des (2019 10) 31102570 Exiting the NIEHS site 2019 
A novel diindolylmethane analog, 1,1-bis(3'-indolyl)-1-(p-chlorophenyl) methane, inhibits the tumor ...   Afzali, Maryam F; Popichak, Katriana A; Burton, Lindsey H; Klochak, Anna L; Wilson, William J; ... R01ES021656 Mol Immunol (2018 09) 29870816 Exiting the NIEHS site 2018 
Compensatory Expression of Nur77 and Nurr1 Regulates NF-κB-Dependent Inflammatory Signaling in Astro ...   Popichak, Katriana A; Hammond, Sean L; Moreno, Julie A; Afzali, Maryam F; Backos, Donald S; Sla ... R01ES021656, R01ES025713 Mol Pharmacol (2018 10) 30111648 Exiting the NIEHS site 2018 
Glial-neuronal signaling mechanisms underlying the neuroinflammatory effects of manganese.   Popichak, Katriana A; Afzali, Maryam F; Kirkley, Kelly S; Tjalkens, Ronald B R01ES021656 J Neuroinflammation (2018 Nov 21) 30463564 Exiting the NIEHS site 2018 
The Nurr1 Ligand,1,1-bis(3'-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Ne ...   Hammond, Sean L; Popichak, Katriana A; Li, Xi; Hunt, Lindsay G; Richman, Evan H; Damale, Prana ... R01ES021656, R01ES025713 J Pharmacol Exp Ther (2018 06) 29626009 Exiting the NIEHS site 2018 
Cellular selectivity of AAV serotypes for gene delivery in neurons and astrocytes by neonatal intrac ...   Hammond, Sean L; Leek, Ashley N; Richman, Evan H; Tjalkens, Ronald B R01ES021656 PLoS One (2017) 29244806 Exiting the NIEHS site 2017 
Inflammatory Activation of Microglia and Astrocytes in Manganese Neurotoxicity.   Tjalkens, Ronald B; Popichak, Katriana A; Kirkley, Kelly A R01ES021656 Adv Neurobiol (2017) 28889267 Exiting the NIEHS site 2017 
Microglia amplify inflammatory activation of astrocytes in manganese neurotoxicity.   Kirkley, Kelly S; Popichak, Katriana A; Afzali, Maryam F; Legare, Marie E; Tjalkens, Ronald B R01ES021656 J Neuroinflammation (2017 05 05) 28476157 Exiting the NIEHS site 2017 
Spontaneous Development of Cutaneous Squamous Cell Carcinoma in Mice with Cell-specific Deletion of ...   Kirkley, Kelly S; Walton, Kelly D; Duncan, Colleen; Tjalkens, Ronald B R01ES021656 Comp Med (2017 Oct 01) 28935002 Exiting the NIEHS site 2017 
Entry Sites of Venezuelan and Western Equine Encephalitis Viruses in the Mouse Central Nervous Syste ...   Phillips, Aaron T; Rico, Amber B; Stauft, Charles B; Hammond, Sean L; Aboellail, Tawfik A; Tjal ... R01ES021656 J Virol (2016 06 15) 27053560 Exiting the NIEHS site 2016 
Nuclear receptor 4A (NR4A) family - orphans no more.   Safe, Stephen; Jin, Un-Ho; Morpurgo, Benjamin; Abudayyeh, Ala; Singh, Mandip; Tjalkens, Ronald ... P30ES005022, R01ES021656 J Steroid Biochem Mol Biol (2016 Mar) 25917081 Exiting the NIEHS site 2016 
Venezuelan and western equine encephalitis virus E1 liposome antigen nucleic acid complexes protect ...   Rico, Amber B; Phillips, Aaron T; Schountz, Tony; Jarvis, Donald L; Tjalkens, Ronald B; Powers, ... R01ES021656 Virology (2016 12) 27632563 Exiting the NIEHS site 2016 
A novel synthetic activator of Nurr1 induces dopaminergic gene expression and protects against 6-hyd ...   Hammond, Sean L; Safe, Stephen; Tjalkens, Ronald B R01ES021656 Neurosci Lett (2015 Oct 21) 26383113 Exiting the NIEHS site 2015 
Angiotensin II regulates brain (pro)renin receptor expression through activation of cAMP response el ...   Li, Wencheng; Liu, Jiao; Hammond, Sean L; Tjalkens, Ronald B; Saifudeen, Zubaida; Feng, Yumei R01ES021656 Am J Physiol Regul Integr Comp Physiol (2015 Jul 15) 25994957 Exiting the NIEHS site 2015 
Novel para-phenyl substituted diindolylmethanes protect against MPTP neurotoxicity and suppress glia ...   De Miranda, Briana R; Popichak, Katriana A; Hammond, Sean L; Miller, James A; Safe, Stephen; Tj ... R01ES021656 Toxicol Sci (2015 Feb) 25406165 Exiting the NIEHS site 2015 
Removal of Trace Elements by Cupric Oxide Nanoparticles from Uranium In Situ Recovery Bleed Water an ...   Schilz, Jodi R; Reddy, K J; Nair, Sreejayan; Johnson, Thomas E; Tjalkens, Ronald B; Krueger, K ... R01ES021656 J Vis Exp (2015) 26132311 Exiting the NIEHS site 2015 
The Nurr1 Activator 1,1-Bis(3'-Indolyl)-1-(p-Chlorophenyl)Methane Blocks Inflammatory Gene Expressio ...   De Miranda, Briana R; Popichak, Katriana A; Hammond, Sean L; Jorgensen, Bryce A; Phillips, Aaro ... R01ES021656 Mol Pharmacol (2015 Jun) 25858541 Exiting the NIEHS site 2015 
Diindolylmethane analogs bind NR4A1 and are NR4A1 antagonists in colon cancer cells.   Lee, Syng-Ook; Li, Xi; Hedrick, Erik; Jin, Un-Ho; Tjalkens, Ronald B; Backos, Donald S; Li, L ... R01ES021656 Mol Endocrinol (2014 Oct) 25099012 Exiting the NIEHS site 2014 
Dopaminergic neurotoxicants cause biphasic inhibition of purinergic calcium signaling in astrocytes.   Streifel, Karin M; Gonzales, Albert L; De Miranda, Briana; Mouneimne, Rola; Earley, Scott; Tjal ... R01ES021656 PLoS One (2014) 25365260 Exiting the NIEHS site 2014 
Repeated exposure to low doses of kainic acid activates nuclear factor kappa B (NF-κB) prior to seiz ...   Miller, James A; Kirkley, Kelly A; Padmanabhan, Rachel; Liang, Li-Ping; Raol, Yogendra H; Patel ... R01ES021656 Neurotoxicology (2014 Sep) 24813937 Exiting the NIEHS site 2014 
Manganese inhibits ATP-induced calcium entry through the transient receptor potential channel TRPC3 ...   Streifel, Karin M; Miller, James; Mouneimne, Rola; Tjalkens, Ronald B R01ES021656 Neurotoxicology (2013 Jan) 23131343 Exiting the NIEHS site 2013 
Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substit ...   De Miranda, Briana R; Miller, James A; Hansen, Ryan J; Lunghofer, Paul J; Safe, Stephen; Gustaf ... R01ES021656 J Pharmacol Exp Ther (2013 Apr) 23318470 Exiting the NIEHS site 2013 
Back
to Top