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Who We Fund: Publication Detail

Project Title: GENOTOXICITY AND REPAIR OF TOBACCO-SPECIFIC NITROSAMINE DNA ADDUCTS
PI: Spratt, Thomas E.
Institution: Pennsylvania State Univ Hershey Med Ctr
Grant Number: R01ES021762

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 17 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/R01ES021762/format/excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Active Site Interactions Impact Phosphoryl Transfer during Replication of Damaged and Undamaged DNA ...   Prakasha Gowda, A S; Spratt, Thomas E R01ES021762 Chem Res Toxicol (2017 11 20) 29053918 Exiting the NIEHS site 2017 
Honokiol Inhibits DNA Polymerases β and λ and Increases Bleomycin Sensitivity of Human Cancer Cells.   Gowda, A S Prakasha; Suo, Zucai; Spratt, Thomas E R01ES021762 Chem Res Toxicol (2017 Feb 20) 28067485 Exiting the NIEHS site 2017 
Mutagenic Replication of N2-Deoxyguanosine Benzo[a]pyrene Adducts by Escherichia coli DNA Polymerase ...   Gowda, A S Prakasha; Krzeminski, Jacek; Amin, Shantu; Suo, Zucai; Spratt, Thomas E R01ES021762 Chem Res Toxicol (2017 05 15) 28402640 Exiting the NIEHS site 2017 
N2 -Substituted 2'-Deoxyguanosine Triphosphate Derivatives as Selective Substrates for Human DNA Pol ...   Gowda, A S Prakasha; Lee, Marietta; Spratt, Thomas E R01ES021762 Angew Chem Int Ed Engl (2017 03 01) 28140505 Exiting the NIEHS site 2017 
Translesion Synthesis of 2'-Deoxyguanosine Lesions by Eukaryotic DNA Polymerases.   Basu, Ashis K; Pande, Paritosh; Bose, Arindam R01ES021762, R01ES023350 Chem Res Toxicol (2017 01 17) 27760288 Exiting the NIEHS site 2017 
DNA Polymerase ν Rapidly Bypasses O6-Methyl-dG but Not O6-[4-(3-Pyridyl)-4-oxobutyl-dG and O2-Alkyl- ...   Gowda, A S Prakasha; Spratt, Thomas E R01ES021762 Chem Res Toxicol (2016 11 21) 27741574 Exiting the NIEHS site 2016 
DNA Polymerases η and ζ Combine to Bypass O(2)-[4-(3-Pyridyl)-4-oxobutyl]thymine, a DNA Adduct Forme ...   Gowda, A S Prakasha; Spratt, Thomas E R01ES021762 Chem Res Toxicol (2016 Mar 21) 26868090 Exiting the NIEHS site 2016 
Mechanism of Error-Free Bypass of the Environmental Carcinogen N-(2'-Deoxyguanosin-8-yl)-3-aminobenz ...   Patra, Amritraj; Politica, Dustin A; Chatterjee, Arindom; Tokarsky, E John; Suo, Zucai; Basu, ... R01ES021762 Chembiochem (2016 11 03) 27556902 Exiting the NIEHS site 2016 
Base-Displaced Intercalated Structure of the N-(2'-Deoxyguanosin-8-yl)-3-aminobenzanthrone DNA Adduc ...   Politica, Dustin A; Malik, Chanchal K; Basu, Ashis K; Stone, Michael P R01ES021762 Chem Res Toxicol (2015 Dec 21) 26641105 Exiting the NIEHS site 2015 
Biological relevance of oxidative debris present in as-prepared graphene oxide.   Pattammattel, Ajith; Williams, Christina L; Pande, Paritosh; Tsui, William G; Basu, Ashis K; Ku ... R01ES021762 RSC Adv (2015 Jan 01) 26257893 Exiting the NIEHS site 2015 
DNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8-2'-deoxyguan ...   Bose, Arindam; Pande, Paritosh; Jasti, Vijay P; Millsap, Amy D; Hawkins, Edward K; Rizzo, Carm ... R01ES021762 Nucleic Acids Res (2015 Sep 30) 26220181 Exiting the NIEHS site 2015 
Human DNA Polymerase ν Catalyzes Correct and Incorrect DNA Synthesis with High Catalytic Efficiency.   Gowda, A S Prakasha; Moldovan, George-Lucian; Spratt, Thomas E R01ES021762 J Biol Chem (2015 Jun 26) 25963146 Exiting the NIEHS site 2015 
Roles of translesion synthesis DNA polymerases in the potent mutagenicity of tobacco-specific nitros ...   Weerasooriya, Savithri; Jasti, Vijay P; Bose, Arindam; Spratt, Thomas E; Basu, Ashis K R01ES021762 DNA Repair (Amst) (2015 Nov) 26460881 Exiting the NIEHS site 2015 
Unlike catalyzing error-free bypass of 8-oxodGuo, DNA polymerase λ is responsible for a significant ...   Pande, Paritosh; Haraguchi, Kazuhiro; Jiang, Yu-Lin; Greenberg, Marc M; Basu, Ashis K R01ES021762 Biochemistry (2015 Mar 17) 25741586 Exiting the NIEHS site 2015 
Mutagenicity and genotoxicity of (5'S)-8,5'-cyclo-2'-deoxyadenosine in Escherichia coli and replicat ...   Pednekar, Varsha; Weerasooriya, Savithri; Jasti, Vijay P; Basu, Ashis K R01ES021762 Chem Res Toxicol (2014 Feb 17) 24392701 Exiting the NIEHS site 2014 
Mutational analysis of the C8-guanine adduct of the environmental carcinogen 3-nitrobenzanthrone in ...   Pande, Paritosh; Malik, Chanchal K; Bose, Arindam; Jasti, Vijay P; Basu, Ashis K R01ES021762 Biochemistry (2014 Aug 19) 25080294 Exiting the NIEHS site 2014 
Replicative bypass of abasic site in Escherichia coli and human cells: similarities and differences.   Weerasooriya, Savithri; Jasti, Vijay P; Basu, Ashis K R01ES021762, R01ES023350 PLoS One (2014) 25226389 Exiting the NIEHS site 2014 
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