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Your Environment. Your Health.

Who We Fund: Publication Detail

Project Title: ENDOCRINE DISRUPTOR MEDIATED ACTIVATION OF PXR CAUSES DYSLIPIDEMIA AND ATHEROSCLEROSIS
PI: Zhou, Changcheng
Institution: University Of California Riverside
Grant Number: R01ES023470

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 18 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/R01ES023470/format/excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Myeloid-specific deficiency of pregnane X receptor decreases atherosclerosis in LDL receptor-deficie ...   Sui, Yipeng; Meng, Zhaojie; Park, Se-Hyung; Lu, Weiwei; Livelo, Christopher; Chen, Qi; Zhou, ... R01ES023470, R01ES023470 J Lipid Res (2020 05) 32170024 Exiting the NIEHS site 2020 
Prebiotic inulin consumption reduces dioxin-like PCB 126-mediated hepatotoxicity and gut dysbiosis i ...   Hoffman, Jessie B; Petriello, Michael C; Morris, Andrew J; Mottaleb, M Abdul; Sui, Yipeng; Zhou ... P42ES007380, R00ES028734, R00ES028734, R01ES023470, R01ES023470 Environ Pollut (2020 Jun) 32105967 Exiting the NIEHS site 2020 
Deficiency of Adipocyte IKKβ Affects Atherosclerotic Plaque Vulnerability in Obese LDLR Deficient Mi ...   Lu, Weiwei; Park, Se-Hyung; Meng, Zhaojie; Wang, Fang; Zhou, Changcheng R01ES023470, R01ES023470 J Am Heart Assoc (2019 06 18) 31203708 Exiting the NIEHS site 2019 
Non-nucleoside reverse transcriptase inhibitor efavirenz activates PXR to induce hypercholesterolemi ...   Gwag, Taesik; Meng, Zhaojie; Sui, Yipeng; Helsley, Robert N; Park, Se-Hyung; Wang, Shuxia; Gre ... P30ES026529, R01ES023470, R01ES023470 J Hepatol (2019 05) 30677459 Exiting the NIEHS site 2019 
The atypical antipsychotic quetiapine induces hyperlipidemia by activating intestinal PXR signaling.   Meng, Zhaojie; Gwag, Taesik; Sui, Yipeng; Park, Se-Hyung; Zhou, Xiangping; Zhou, Changcheng R01ES023470, R01ES023470 JCI Insight (2019 Feb 07) 30728326 Exiting the NIEHS site 2019 
IKKβ is a β-catenin kinase that regulates mesenchymal stem cell differentiation.   Sui, Yipeng; Liu, Zun; Park, Se-Hyung; Thatcher, Sean E; Zhu, Beibei; Fernandez, Joseph P; Mol ... R01ES023470, R01ES023470 JCI Insight (2018 01 25) 29367460 Exiting the NIEHS site 2018 
Myeloid β-Catenin Deficiency Exacerbates Atherosclerosis in Low-Density Lipoprotein Receptor-Deficie ...   Wang, Fang; Liu, Zun; Park, Se-Hyung; Gwag, Taesik; Lu, Weiwei; Ma, Murong; Sui, Yipeng; Zhou ... R01ES023470, R01ES023470 Arterioscler Thromb Vasc Biol (2018 07) 29724817 Exiting the NIEHS site 2018 
Myeloid-specific deletion of thrombospondin 1 protects against inflammation and insulin resistance i ...   Memetimin, Hasiyet; Li, Dong; Tan, Kaiyuan; Zhou, Changcheng; Liang, Ying; Wu, Yadi; Wang, Sh ... P30ES026529, R01ES023470, R01ES023470 Am J Physiol Endocrinol Metab (2018 12 01) 30351986 Exiting the NIEHS site 2018 
Perinatal Bisphenol A Exposure Increases Atherosclerosis in Adult Male PXR-Humanized Mice.   Sui, Yipeng; Park, Se-Hyung; Wang, Fang; Zhou, Changcheng R01ES023470, R01ES023470 Endocrinology (2018 04 01) 29425287 Exiting the NIEHS site 2018 
Epigenetic impact of endocrine disrupting chemicals on lipid homeostasis and atherosclerosis: a preg ...   Helsley, Robert N; Zhou, Changcheng R01ES023470, R01ES023470 Environ Epigenet (2017 Oct 01) 29119010 Exiting the NIEHS site 2017 
IKKβ Is Essential for Adipocyte Survival and Adaptive Adipose Remodeling in Obesity.   Park, Se-Hyung; Liu, Zun; Sui, Yipeng; Helsley, Robert N; Zhu, Beibei; Powell, David K; Kern, ... R01ES023470, R01ES023470 Diabetes (2016 06) 26993069 Exiting the NIEHS site 2016 
Novel functions of PXR in cardiometabolic disease.   Zhou, Changcheng R01ES023470, R01ES023470 Biochim Biophys Acta (2016 09) 26924429 Exiting the NIEHS site 2016 
Targeting IκB kinase β in Adipocyte Lineage Cells for Treatment of Obesity and Metabolic Dysfunction ...   Helsley, Robert N; Sui, Yipeng; Park, Se-Hyung; Liu, Zun; Lee, Richard G; Zhu, Beibei; Kern, ... R01ES023470, R01ES023470 Stem Cells (2016 07) 26991836 Exiting the NIEHS site 2016 
Interaction of thrombospondin1 and CD36 contributes to obesity-associated podocytopathy.   Cui, Wenpeng; Maimaitiyiming, Hasiyeti; Zhou, Qi; Norman, Heather; Zhou, Changcheng; Wang, Shu ... R01ES023470, R01ES023470 Biochim Biophys Acta (2015 Jul) 25835637 Exiting the NIEHS site 2015 
Intestinal pregnane X receptor links xenobiotic exposure and hypercholesterolemia.   Sui, Yipeng; Helsley, Robert N; Park, Se-Hyung; Song, Xiulong; Liu, Zun; Zhou, Changcheng R01ES023470, R01ES023470 Mol Endocrinol (2015 May) 25811240 Exiting the NIEHS site 2015 
Bisphenol A increases atherosclerosis in pregnane X receptor-humanized ApoE deficient mice.   Sui, Yipeng; Park, Se-Hyung; Helsley, Robert N; Sunkara, Manjula; Gonzalez, Frank J; Morris, A ... P42ES007380, R01ES023470, R01ES023470 J Am Heart Assoc (2014 Apr 22) 24755147 Exiting the NIEHS site 2014 
IKKβ links vascular inflammation to obesity and atherosclerosis.   Sui, Yipeng; Park, Se-Hyung; Xu, Jinxian; Monette, Sébastien; Helsley, Robert N; Han, Seong-Su ... R01ES023470, R01ES023470 J Exp Med (2014 May 5) 24799533 Exiting the NIEHS site 2014 
Pregnane X receptor mediates dyslipidemia induced by the HIV protease inhibitor amprenavir in mice.   Helsley, Robert N; Sui, Yipeng; Ai, Ni; Park, Se-Hyung; Welsh, William J; Zhou, Changcheng P30ES005022, R01ES023470, R01ES023470 Mol Pharmacol (2013 Jun) 23519392 Exiting the NIEHS site 2013 
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