| Project Title: | CYTOPLASMIC-NUCLEAR REDOX SIGNALING: DISRUPTION BY DIETARY CADMIUM LEVELS |
|---|---|
| PI: | Jones, Dean Paul |
| Institution: | Emory University |
| Grant Number: | R01ES023485 |
These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| Environmental chemicals and metabolic disruption in primary and secondary human parathyroid tumors. | Hu, Xin; Saunders, Neil; Safley, Susan; Smith, Matthew Ryan; Liang, Yongliang; Tran, ViLinh; S ... | P30ES019776, R01ES023485, U2CES030163 | Surgery (2021 Jan) |
32771296
|
2021 |
| Metabolome-wide association study of flavorant vanillin exposure in bronchial epithelial cells revea ... | Smith, Matthew Ryan; Jarrell, Zachery R; Orr, Michael; Liu, Ken H; Go, Young-Mi; Jones, Dean P | P30ES019776, R01ES023485, R21ES031824, T32ES012870, U2CES030163 | Environ Int (2021 Feb) |
33360165
|
2021 |
| A precision medicine approach to defining the impact of doxorubicin on the bioenergetic-metabolite i ... | Smith, Matthew Ryan; Chacko, Balu K; Johnson, Michelle S; Benavides, Gloria A; Uppal, Karan; Go ... | P30ES019776, R01ES023485, U2CES026560 | Redox Biol (2020 01) |
31546171
|
2020 |
| A vision for exposome epidemiology: The pregnancy exposome in relation to breast cancer in the Child ... | Jones, Dean P; Cohn, Barbara A | P30ES019776, R01ES023485, U2CES026560, U2CES030163 | Reprod Toxicol (2020 03) |
32197999
|
2020 |
| Macronutrient, Energy, and Bile Acid Metabolism Pathways Altered Following a Physiological Meal Chal ... | Yu, Elaine A; Yu, Tianwei; Jones, Dean P; Martorell, Reynaldo; Ramirez-Zea, Manuel; Stein, Ary ... | P30ES019776, R01ES023485, U2CES030163 | J Nutr (2020 08 01) |
32597983
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2020 |
| Metabolomic Profiling After a Meal Shows Greater Changes and Lower Metabolic Flexibility in Cardiome ... | Yu, Elaine A; Yu, Tianwei; Jones, Dean P; Ramirez-Zea, Manuel; Stein, Aryeh D | P30ES019776, R01ES023485, U2CES030163 | J Endocr Soc (2020 Nov 01) |
33134764
|
2020 |
| MTOR-initiated metabolic switch and degeneration in the retinal pigment epithelium. | Go, Young-Mi; Zhang, Jing; Fernandes, Jolyn; Litwin, Christopher; Chen, Rui; Wensel, Theodore ... | R01ES023485 | FASEB J (2020 Sep) |
32721041
|
2020 |
| Omics Integration for Mitochondria Systems Biology. | Hu, Xin; Go, Young-Mi; Jones, Dean P | P30ES019776, R01ES023485, U2CES030163 | Antioxid Redox Signal (2020 04 20) |
31891667
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2020 |
| Plasma acylcarnitine levels increase with healthy aging. | Jarrell, Zachery R; Smith, M Ryan; Hu, Xin; Orr, Michael; Liu, Ken H; Quyyumi, Arshed A; Jones ... | R01ES023485 | Aging (Albany NY) (2020 06 16) |
32554854
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2020 |
| Reference Standardization for Quantification and Harmonization of Large-Scale Metabolomics. | Liu, Ken H; Nellis, Mary; Uppal, Karan; Ma, Chunyu; Tran, ViLinh; Liang, Yongliang; Walker, D ... | P30ES019776, R01ES023485, U2CES030163 | Anal Chem (2020 07 07) |
32490663
|
2020 |
| Sampling interstitial fluid from human skin using a microneedle patch. | Samant, Pradnya P; Niedzwiecki, Megan M; Raviele, Nicholas; Tran, Vilinh; Mena-Lapaix, Juan; Wa ... | P30ES019776, R01ES023485, U2CES026560 | Sci Transl Med (2020 11 25) |
33239384
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2020 |
| Associations of Benzo(ghi)perylene and Heptachlorodibenzo-p-dioxin in Serum of Service Personnel Dep ... | Smith, Matthew Ryan; Woeller, Collynn F; Uppal, Karan; Thatcher, Thomas H; Walker, Douglas I; H ... | P30ES019776, R01ES023485, U2CES030163 | J Occup Environ Med (2019 12) |
31800449
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2019 |
| Benzo[a]pyrene Perturbs Mitochondrial and Amino Acid Metabolism in Lung Epithelial Cells and Has Sim ... | Smith, Matthew Ryan; Walker, Douglas I; Uppal, Karan; Utell, Mark J; Hopke, Philip K; Mallon, ... | P30ES019776, R01ES023485 | J Occup Environ Med (2019 12) |
31800453
|
2019 |
| Environmental Cadmium Enhances Lung Injury by Respiratory Syncytial Virus Infection. | Hu, Xin; Kim, Ki-Hye; Lee, Youri; Fernandes, Jolyn; Smith, M Ryan; Jung, Yu-Jin; Orr, Michael ... | P30ES019776, R01ES023485 | Am J Pathol (2019 08) |
31108100
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2019 |
| Environmental Chemicals Altered in Association With Deployment for High Risk Areas. | Smith, Matthew Ryan; Uppal, Karan; Walker, Douglas I; Utell, Mark J; Hopke, Philip K; Mallon, ... | P30ES019776, R01ES023485 | J Occup Environ Med (2019 12) |
31800447
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2019 |
| Integrative Network Analysis Linking Clinical Outcomes With Environmental Exposures and Molecular Va ... | Thakar, Juilee; Thatcher, Thomas H; Smith, Matthew Ryan; Woeller, Collynn F; Walker, Douglas I; ... | P30ES001247, P30ES019776, R01ES023485 | J Occup Environ Med (2019 12) |
31800452
|
2019 |
| Low-dose cadmium disrupts mitochondrial citric acid cycle and lipid metabolism in mouse lung. | Hu, Xin; Chandler, Joshua D; Park, Soojin; Liu, Ken; Fernandes, Jolyn; Orr, Michael; Smith, M ... | P30ES019776, R01ES023485, U2CES026560 | Free Radic Biol Med (2019 02 01) |
30529385
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2019 |
| Low-dose cadmium potentiates lung inflammatory response to 2009 pandemic H1N1 influenza virus in mic ... | Chandler, Joshua D; Hu, Xin; Ko, Eun-Ju; Park, Soojin; Fernandes, Jolyn; Lee, Young-Tae; Orr, ... | R01ES023485 | Environ Int (2019 06) |
30999129
|
2019 |
| Metabolic perturbations in classic galactosemia beyond the Leloir pathway: Insights from an untarget ... | Taylor Fischer, S; Frederick, Allison B; Tran, ViLinh; Li, Shuzhao; Jones, Dean P; Fridovich-Ke ... | P30ES019776, R01ES023485 | J Inherit Metab Dis (2019 03) |
30667068
|
2019 |
| Metabolome-Wide Association Study of Deployment to Balad, Iraq or Bagram, Afghanistan. | Go, Young-Mi; Smith, Matthew R; Walker, Douglas I; Uppal, Karan; Rohrbeck, Patricia; Krahl, Pa ... | P30ES019776, R01ES023485 | J Occup Environ Med (2019 12) |
31800448
|
2019 |
| Metabolomic assessment of exposure to near-highway ultrafine particles. | Walker, Douglas I; Lane, Kevin J; Liu, Ken; Uppal, Karan; Patton, Allison P; Durant, John L; J ... | P30ES019776, R01ES023485 | J Expo Sci Environ Epidemiol (2019 06) |
30518795
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2019 |
| Metabolomic Responses to Manganese Dose in SH-SY5Y Human Neuroblastoma Cells. | Fernandes, Jolyn; Chandler, Joshua D; Liu, Ken H; Uppal, Karan; Hao, Li; Hu, Xin; Go, Young-M ... | P30ES019776, R01ES023485 | Toxicol Sci (2019 05 01) |
30715528
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2019 |
| Mitochondria in precision medicine; linking bioenergetics and metabolomics in platelets. | Chacko, Balu K; Smith, Matthew R; Johnson, Michelle S; Benavides, Gloria; Culp, Matilda L; Pill ... | P30ES019776, R01ES023485, U2CES026560 | Redox Biol (2019 04) |
30877854
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2019 |
| Phytochelatin database: a resource for phytochelatin complexes of nutritional and environmental meta ... | Dennis, Kristine K; Uppal, Karan; Liu, Ken H; Ma, Chunyu; Liang, Bill; Go, Young-Mi; Jones, D ... | P30ES019776, R01ES023485, U2CES030163 | Database (Oxford) (2019 01 01) |
31267134
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2019 |
| Redox Systems Biology of Nutrition and Oxidative Stress. | Dennis, Kristine K; Go, Young-Mi; Jones, Dean P | P30ES019776, R01ES023485 | J Nutr (2019 04 01) |
30949678
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2019 |
| Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in ... | Fernandes, Jolyn; Chandler, Joshua D; Lili, Loukia N; Uppal, Karan; Hu, Xin; Hao, Li; Go, You ... | P30ES019776, R01ES023485 | Front Genet (2019) |
31396262
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2019 |
| Determination of thiocyanate in exhaled breath condensate. | Chandler, Joshua D; Horati, Hamed; Walker, Douglas I; Pagliano, Enea; Tirouvanziam, Rabindra; V ... | P30ES019776, R01ES023485, U2CES026560 | Free Radic Biol Med (2018 10) |
30144632
|
2018 |
| Mitochondrial network responses in oxidative physiology and disease. | Go, Young-Mi; Fernandes, Jolyn; Hu, Xin; Uppal, Karan; Jones, Dean P | P30ES019776, R01ES023485 | Free Radic Biol Med (2018 02 20) |
29317273
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2018 |
| Myeloperoxidase oxidation of methionine associates with early cystic fibrosis lung disease. | Chandler, Joshua D; Margaroli, Camilla; Horati, Hamed; Kilgore, Matthew B; Veltman, Mieke; Liu, ... | P30ES019776, R01ES023485 | Eur Respir J (2018 10) |
30190273
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2018 |
| Oxidative stress predicts cognitive decline with aging in healthy adults: an observational study. | Hajjar, Ihab; Hayek, Salim S; Goldstein, Felicia C; Martin, Greg; Jones, Dean P; Quyyumi, Arsh ... | P30ES019776, R01ES023485 | J Neuroinflammation (2018 Jan 16) |
29338747
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2018 |
| Putrescine as indicator of manganese neurotoxicity: Dose-response study in human SH-SY5Y cells. | Fernandes, Jolyn; Chandler, Joshua D; Liu, Ken H; Uppal, Karan; Go, Young-Mi; Jones, Dean P | P30ES019776, R01ES023485 | Food Chem Toxicol (2018 Jun) |
29684492
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2018 |
| Redox Equivalents and Mitochondrial Bioenergetics. | Roede, James R; Go, Young-Mi; Jones, Dean P | R01ES023485, T32ES012870 | Methods Mol Biol (2018) |
29851002
|
2018 |
| Selenium at the redox interface of the genome, metabolome and exposome. | Fernandes, Jolyn; Hu, Xin; Ryan Smith, M; Go, Young-Mi; Jones, Dean P | R01ES023485 | Free Radic Biol Med (2018 11 01) |
29883789
|
2018 |
| Selenium Supplementation Alters Hepatic Energy and Fatty Acid Metabolism in Mice. | Hu, Xin; Chandler, Joshua D; Orr, Michael L; Hao, Li; Liu, Ken; Uppal, Karan; Go, Young-Mi; J ... | P30ES019776, R01ES023485 | J Nutr (2018 05 01) |
29982657
|
2018 |
| Selenium supplementation prevents metabolic and transcriptomic responses to cadmium in mouse lung. | Hu, Xin; Chandler, Joshua D; Fernandes, Jolyn; Orr, Michael L; Hao, Li; Uppal, Karan; Neujahr, ... | P30ES019776, R01ES023485 | Biochim Biophys Acta Gen Subj (2018 Nov) |
29656123
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2018 |
| xMWAS: a data-driven integration and differential network analysis tool. | Uppal, Karan; Ma, Chunyu; Go, Young-Mi; Jones, Dean P; Wren, Jonathan | P30ES019776, R01ES023485 | Bioinformatics (2018 02 15) |
29069296
|
2018 |
| Cadmium stimulates myofibroblast differentiation and mouse lung fibrosis. | Hu, Xin; Fernandes, Jolyn; Jones, Dean P; Go, Young-Mi | R01ES023485 | Toxicology (2017 05 15) |
28341147
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2017 |
| From the Cover: Manganese Stimulates Mitochondrial H2O2 Production in SH-SY5Y Human Neuroblastoma Ce ... | Fernandes, Jolyn; Hao, Li; Bijli, Kaiser M; Chandler, Joshua D; Orr, Michael; Hu, Xin; Jones, ... | P30ES019776, R01ES023485 | Toxicol Sci (2017 01) |
27701121
|
2017 |
| Redox dynamics of manganese as a mitochondrial life-death switch. | Smith, Matthew Ryan; Fernandes, Jolyn; Go, Young-Mi; Jones, Dean P | R01ES023485 | Biochem Biophys Res Commun (2017 01 15) |
28212723
|
2017 |
| Redox theory of aging: implications for health and disease. | Go, Young-Mi; Jones, Dean P | P30ES019776, R01ES023485 | Clin Sci (Lond) (2017 Jul 15) |
28667066
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2017 |
| xMSannotator: An R Package for Network-Based Annotation of High-Resolution Metabolomics Data. | Uppal, Karan; Walker, Douglas I; Jones, Dean P | P30ES019776, R01ES023485 | Anal Chem (2017 01 17) |
27977166
|
2017 |
| Yale school of public health symposium on lifetime exposures and human health: the exposome; summary ... | Johnson, Caroline H; Athersuch, Toby J; Collman, Gwen W; Dhungana, Suraj; Grant, David F; Jones ... | P30ES019776, R01ES023485, U2CES026560 | Hum Genomics (2017 Dec 08) |
29221465
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2017 |
| Computational Metabolomics: A Framework for the Million Metabolome. | Uppal, Karan; Walker, Douglas I; Liu, Ken; Li, Shuzhao; Go, Young-Mi; Jones, Dean P | P30ES019776, R01ES023485, T32ES012870, U2CES026560 | Chem Res Toxicol (2016 12 19) |
27629808
|
2016 |
| Deployment-Associated Exposure Surveillance With High-Resolution Metabolomics. | Walker, Douglas I; Mallon, Col Timothy M; Hopke, Philip K; Uppal, Karan; Go, Young-Mi; Rohrbeck ... | P30ES019776, R01ES023485, T32ES012870 | J Occup Environ Med (2016 08) |
27501099
|
2016 |
| Exposure Memory and Lung Regeneration. | Go, Young-Mi; Jones, Dean P | R01ES023485 | Ann Am Thorac Soc (2016 12) |
28005420
|
2016 |
| Hydrogen peroxide and central redox theory for aerobic life: A tribute to Helmut Sies: Scout, trailb ... | Jones, Dean P | P30ES019776, R01ES023485, U2CES026560 | Arch Biochem Biophys (2016 Apr 01) |
27095208
|
2016 |
| Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat d ... | Rao, Anuradha; Kosters, Astrid; Mells, Jamie E; Zhang, Wujuan; Setchell, Kenneth D R; Amanso, ... | P30ES019776, R01ES023485 | Sci Transl Med (2016 09 21) |
27655848
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2016 |
| Low-dose oral cadmium increases airway reactivity and lung neuronal gene expression in mice. | Chandler, Joshua D; Wongtrakool, Cherry; Banton, Sophia A; Li, Shuzhao; Orr, Michael L; Barr, ... | R01ES023485, T32ES012870 | Physiol Rep (2016 Jul) |
27401458
|
2016 |
| Metabolic Pathways and Networks Associated With Tobacco Use in Military Personnel. | Jones, Dean P; Walker, Douglas I; Uppal, Karan; Rohrbeck, Patricia; Mallon, Col Timothy M; Go, ... | P30ES019776, R01ES023485, T32ES012870 | J Occup Environ Med (2016 08) |
27501098
|
2016 |
| Metabolic pathways of lung inflammation revealed by high-resolution metabolomics (HRM) of H1N1 influ ... | Chandler, Joshua D; Hu, Xin; Ko, Eun-Ju; Park, Soojin; Lee, Young-Tae; Orr, Michael; Fernandes ... | R01ES023485 | Am J Physiol Regul Integr Comp Physiol (2016 11 01) |
27558316
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2016 |
| Metabolomics and Mycobacterial Disease: Don't Forget the Bioinformatics. | Collins, Jeffrey M; Kempker, Russell R; Ziegler, Thomas R; Blumberg, Henry M; Jones, Dean P | P30ES019776, R01ES023485, T32ES012870 | Ann Am Thorac Soc (2016 Jan) |
26730872
|
2016 |
| Nuclear Thioredoxin-1 Overexpression Attenuates Alcohol-Mediated Nrf2 Signaling and Lung Fibrosis. | Sueblinvong, Viranuj; Mills, Stephen T; Neujahr, David C; Go, Young-Mi; Jones, Dean P; Guidot, ... | R01ES023485 | Alcohol Clin Exp Res (2016 09) |
27436123
|
2016 |
| Sequencing the exposome: A call to action. | Jones, Dean P | P30ES019776, R01ES023485, T32ES012870 | Toxicol Rep (2016) |
26722641
|
2016 |
| Anticancer therapeutic potential of Mn porphyrin/ascorbate system. | Tovmasyan, Artak; Sampaio, Romulo S; Boss, Mary-Keara; Bueno-Janice, Jacqueline C; Bader, Bader ... | R01ES023485 | Free Radic Biol Med (2015 Dec) |
26496207
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2015 |
| Disturbed flow induces systemic changes in metabolites in mouse plasma: a metabolomics study using A ... | Go, Young-Mi; Kim, Chan Woo; Walker, Douglas I; Kang, Dong Won; Kumar, Sandeep; Orr, Michael; ... | R01ES023485 | Am J Physiol Regul Integr Comp Physiol (2015 Jan 01) |
25377480
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2015 |
| Low-Dose Cadmium Causes Metabolic and Genetic Dysregulation Associated With Fatty Liver Disease in M ... | Go, Young-Mi; Sutliff, Roy L; Chandler, Joshua D; Khalidur, Rahman; Kang, Bum-Yong; Anania, Fr ... | P30ES019776, R01ES023485, T32ES012870 | Toxicol Sci (2015 Oct) |
26187450
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2015 |
| Metabolic Characterization of the Common Marmoset (Callithrix jacchus). | Go, Young-Mi; Liang, Yongliang; Uppal, Karan; Soltow, Quinlyn A; Promislow, Daniel E L; Wachtma ... | P30ES019776, R01ES023485, T32ES012870 | PLoS One (2015) |
26581102
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2015 |
| Metabolome-wide association study of phenylalanine in plasma of common marmosets. | Go, Young-Mi; Walker, Douglas I; Soltow, Quinlyn A; Uppal, Karan; Wachtman, Lynn M; Strobel, F ... | P30ES019776, R01ES023485, T32ES012870 | Amino Acids (2015 Mar) |
25526869
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2015 |
| Metabolome-Wide Association Study of Primary Open Angle Glaucoma. | Burgess, L Goodwin; Uppal, Karan; Walker, Douglas I; Roberson, Rachel M; Tran, ViLinh; Parks, ... | P30ES019776, R01ES023485, T32ES012870 | Invest Ophthalmol Vis Sci (2015 Jul) |
26230767
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2015 |
| Redox theory of aging. | Jones, Dean P | P30ES019776, R01ES023485, T32ES012870 | Redox Biol (2015 Aug) |
25863726
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2015 |
| Reference Standardization for Mass Spectrometry and High-resolution Metabolomics Applications to Exp ... | Go, Young-Mi; Walker, Douglas I; Liang, Yongliang; Uppal, Karan; Soltow, Quinlyn A; Tran, ViLi ... | P30ES019776, R01ES023485, T32ES012870 | Toxicol Sci (2015 Dec) |
26358001
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2015 |
| The cysteine proteome. | Go, Young-Mi; Chandler, Joshua D; Jones, Dean P | P30ES019776, R01ES023485, T32ES012870 | Free Radic Biol Med (2015 Jul) |
25843657
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2015 |
| The Redox Code. | Jones, Dean P; Sies, Helmut | P30ES019776, R01ES023485, T32ES012870 | Antioxid Redox Signal (2015 Sep 20) |
25891126
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2015 |
| Disturbed flow enhances inflammatory signaling and atherogenesis by increasing thioredoxin-1 level i ... | Go, Young-Mi; Son, Dong Ju; Park, Heonyong; Orr, Michael; Hao, Li; Takabe, Wakako; Kumar, San ... | R01ES023485 | PLoS One (2014) |
25265386
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2014 |
| Mitochondrial metabolomics using high-resolution Fourier-transform mass spectrometry. | Go, Young-Mi; Uppal, Karan; Walker, Douglas I; Tran, ViLinh; Dury, Lauriane; Strobel, Frederic ... | R01ES023485, T32ES012870 | Methods Mol Biol (2014) |
25270922
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2014 |
| Transcriptome-metabolome wide association study (TMWAS) of maneb and paraquat neurotoxicity reveals ... | Roede, James R; Uppal, Karan; Park, Youngja; Tran, ViLinh; Jones, Dean P | P30ES019776, R01ES023485 | Toxicol Rep (2014) |
27722094
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2014 |