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Your Environment. Your Health.

Who We Fund: Publication Detail

Project Title: CYTOPLASMIC-NUCLEAR REDOX SIGNALING: DISRUPTION BY DIETARY CADMIUM LEVELS
PI: Jones, Dean Paul
Institution: Emory University
Grant Number: R01ES023485

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 66 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/grantpubdetail/grant_number/R01ES023485/format/excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Environmental chemicals and metabolic disruption in primary and secondary human parathyroid tumors.   Hu, Xin; Saunders, Neil; Safley, Susan; Smith, Matthew Ryan; Liang, Yongliang; Tran, ViLinh; S ... P30ES019776, R01ES023485, U2CES030163 Surgery (2021 Jan) 32771296 Exiting the NIEHS site 2021 
Metabolome-wide association study of flavorant vanillin exposure in bronchial epithelial cells revea ...   Smith, Matthew Ryan; Jarrell, Zachery R; Orr, Michael; Liu, Ken H; Go, Young-Mi; Jones, Dean P P30ES019776, R01ES023485, R21ES031824, T32ES012870, U2CES030163 Environ Int (2021 Feb) 33360165 Exiting the NIEHS site 2021 
A precision medicine approach to defining the impact of doxorubicin on the bioenergetic-metabolite i ...   Smith, Matthew Ryan; Chacko, Balu K; Johnson, Michelle S; Benavides, Gloria A; Uppal, Karan; Go ... P30ES019776, R01ES023485, U2CES026560 Redox Biol (2020 01) 31546171 Exiting the NIEHS site 2020 
A vision for exposome epidemiology: The pregnancy exposome in relation to breast cancer in the Child ...   Jones, Dean P; Cohn, Barbara A P30ES019776, R01ES023485, U2CES026560, U2CES030163 Reprod Toxicol (2020 03) 32197999 Exiting the NIEHS site 2020 
Macronutrient, Energy, and Bile Acid Metabolism Pathways Altered Following a Physiological Meal Chal ...   Yu, Elaine A; Yu, Tianwei; Jones, Dean P; Martorell, Reynaldo; Ramirez-Zea, Manuel; Stein, Ary ... P30ES019776, R01ES023485, U2CES030163 J Nutr (2020 08 01) 32597983 Exiting the NIEHS site 2020 
Metabolomic Profiling After a Meal Shows Greater Changes and Lower Metabolic Flexibility in Cardiome ...   Yu, Elaine A; Yu, Tianwei; Jones, Dean P; Ramirez-Zea, Manuel; Stein, Aryeh D P30ES019776, R01ES023485, U2CES030163 J Endocr Soc (2020 Nov 01) 33134764 Exiting the NIEHS site 2020 
MTOR-initiated metabolic switch and degeneration in the retinal pigment epithelium.   Go, Young-Mi; Zhang, Jing; Fernandes, Jolyn; Litwin, Christopher; Chen, Rui; Wensel, Theodore ... R01ES023485 FASEB J (2020 Sep) 32721041 Exiting the NIEHS site 2020 
Omics Integration for Mitochondria Systems Biology.   Hu, Xin; Go, Young-Mi; Jones, Dean P P30ES019776, R01ES023485, U2CES030163 Antioxid Redox Signal (2020 04 20) 31891667 Exiting the NIEHS site 2020 
Plasma acylcarnitine levels increase with healthy aging.   Jarrell, Zachery R; Smith, M Ryan; Hu, Xin; Orr, Michael; Liu, Ken H; Quyyumi, Arshed A; Jones ... R01ES023485 Aging (Albany NY) (2020 06 16) 32554854 Exiting the NIEHS site 2020 
Reference Standardization for Quantification and Harmonization of Large-Scale Metabolomics.   Liu, Ken H; Nellis, Mary; Uppal, Karan; Ma, Chunyu; Tran, ViLinh; Liang, Yongliang; Walker, D ... P30ES019776, R01ES023485, U2CES030163 Anal Chem (2020 07 07) 32490663 Exiting the NIEHS site 2020 
Sampling interstitial fluid from human skin using a microneedle patch.   Samant, Pradnya P; Niedzwiecki, Megan M; Raviele, Nicholas; Tran, Vilinh; Mena-Lapaix, Juan; Wa ... P30ES019776, R01ES023485, U2CES026560 Sci Transl Med (2020 11 25) 33239384 Exiting the NIEHS site 2020 
Associations of Benzo(ghi)perylene and Heptachlorodibenzo-p-dioxin in Serum of Service Personnel Dep ...   Smith, Matthew Ryan; Woeller, Collynn F; Uppal, Karan; Thatcher, Thomas H; Walker, Douglas I; H ... P30ES019776, R01ES023485, U2CES030163 J Occup Environ Med (2019 12) 31800449 Exiting the NIEHS site 2019 
Benzo[a]pyrene Perturbs Mitochondrial and Amino Acid Metabolism in Lung Epithelial Cells and Has Sim ...   Smith, Matthew Ryan; Walker, Douglas I; Uppal, Karan; Utell, Mark J; Hopke, Philip K; Mallon, ... P30ES019776, R01ES023485 J Occup Environ Med (2019 12) 31800453 Exiting the NIEHS site 2019 
Environmental Cadmium Enhances Lung Injury by Respiratory Syncytial Virus Infection.   Hu, Xin; Kim, Ki-Hye; Lee, Youri; Fernandes, Jolyn; Smith, M Ryan; Jung, Yu-Jin; Orr, Michael ... P30ES019776, R01ES023485 Am J Pathol (2019 08) 31108100 Exiting the NIEHS site 2019 
Environmental Chemicals Altered in Association With Deployment for High Risk Areas.   Smith, Matthew Ryan; Uppal, Karan; Walker, Douglas I; Utell, Mark J; Hopke, Philip K; Mallon, ... P30ES019776, R01ES023485 J Occup Environ Med (2019 12) 31800447 Exiting the NIEHS site 2019 
Integrative Network Analysis Linking Clinical Outcomes With Environmental Exposures and Molecular Va ...   Thakar, Juilee; Thatcher, Thomas H; Smith, Matthew Ryan; Woeller, Collynn F; Walker, Douglas I; ... P30ES001247, P30ES019776, R01ES023485 J Occup Environ Med (2019 12) 31800452 Exiting the NIEHS site 2019 
Low-dose cadmium disrupts mitochondrial citric acid cycle and lipid metabolism in mouse lung.   Hu, Xin; Chandler, Joshua D; Park, Soojin; Liu, Ken; Fernandes, Jolyn; Orr, Michael; Smith, M ... P30ES019776, R01ES023485, U2CES026560 Free Radic Biol Med (2019 02 01) 30529385 Exiting the NIEHS site 2019 
Low-dose cadmium potentiates lung inflammatory response to 2009 pandemic H1N1 influenza virus in mic ...   Chandler, Joshua D; Hu, Xin; Ko, Eun-Ju; Park, Soojin; Fernandes, Jolyn; Lee, Young-Tae; Orr, ... R01ES023485 Environ Int (2019 06) 30999129 Exiting the NIEHS site 2019 
Metabolic perturbations in classic galactosemia beyond the Leloir pathway: Insights from an untarget ...   Taylor Fischer, S; Frederick, Allison B; Tran, ViLinh; Li, Shuzhao; Jones, Dean P; Fridovich-Ke ... P30ES019776, R01ES023485 J Inherit Metab Dis (2019 03) 30667068 Exiting the NIEHS site 2019 
Metabolome-Wide Association Study of Deployment to Balad, Iraq or Bagram, Afghanistan.   Go, Young-Mi; Smith, Matthew R; Walker, Douglas I; Uppal, Karan; Rohrbeck, Patricia; Krahl, Pa ... P30ES019776, R01ES023485 J Occup Environ Med (2019 12) 31800448 Exiting the NIEHS site 2019 
Metabolomic assessment of exposure to near-highway ultrafine particles.   Walker, Douglas I; Lane, Kevin J; Liu, Ken; Uppal, Karan; Patton, Allison P; Durant, John L; J ... P30ES019776, R01ES023485 J Expo Sci Environ Epidemiol (2019 06) 30518795 Exiting the NIEHS site 2019 
Metabolomic Responses to Manganese Dose in SH-SY5Y Human Neuroblastoma Cells.   Fernandes, Jolyn; Chandler, Joshua D; Liu, Ken H; Uppal, Karan; Hao, Li; Hu, Xin; Go, Young-M ... P30ES019776, R01ES023485 Toxicol Sci (2019 05 01) 30715528 Exiting the NIEHS site 2019 
Mitochondria in precision medicine; linking bioenergetics and metabolomics in platelets.   Chacko, Balu K; Smith, Matthew R; Johnson, Michelle S; Benavides, Gloria; Culp, Matilda L; Pill ... P30ES019776, R01ES023485, U2CES026560 Redox Biol (2019 04) 30877854 Exiting the NIEHS site 2019 
Phytochelatin database: a resource for phytochelatin complexes of nutritional and environmental meta ...   Dennis, Kristine K; Uppal, Karan; Liu, Ken H; Ma, Chunyu; Liang, Bill; Go, Young-Mi; Jones, D ... P30ES019776, R01ES023485, U2CES030163 Database (Oxford) (2019 01 01) 31267134 Exiting the NIEHS site 2019 
Redox Systems Biology of Nutrition and Oxidative Stress.   Dennis, Kristine K; Go, Young-Mi; Jones, Dean P P30ES019776, R01ES023485 J Nutr (2019 04 01) 30949678 Exiting the NIEHS site 2019 
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in ...   Fernandes, Jolyn; Chandler, Joshua D; Lili, Loukia N; Uppal, Karan; Hu, Xin; Hao, Li; Go, You ... P30ES019776, R01ES023485 Front Genet (2019) 31396262 Exiting the NIEHS site 2019 
Determination of thiocyanate in exhaled breath condensate.   Chandler, Joshua D; Horati, Hamed; Walker, Douglas I; Pagliano, Enea; Tirouvanziam, Rabindra; V ... P30ES019776, R01ES023485, U2CES026560 Free Radic Biol Med (2018 10) 30144632 Exiting the NIEHS site 2018 
Mitochondrial network responses in oxidative physiology and disease.   Go, Young-Mi; Fernandes, Jolyn; Hu, Xin; Uppal, Karan; Jones, Dean P P30ES019776, R01ES023485 Free Radic Biol Med (2018 02 20) 29317273 Exiting the NIEHS site 2018 
Myeloperoxidase oxidation of methionine associates with early cystic fibrosis lung disease.   Chandler, Joshua D; Margaroli, Camilla; Horati, Hamed; Kilgore, Matthew B; Veltman, Mieke; Liu, ... P30ES019776, R01ES023485 Eur Respir J (2018 10) 30190273 Exiting the NIEHS site 2018 
Oxidative stress predicts cognitive decline with aging in healthy adults: an observational study.   Hajjar, Ihab; Hayek, Salim S; Goldstein, Felicia C; Martin, Greg; Jones, Dean P; Quyyumi, Arsh ... P30ES019776, R01ES023485 J Neuroinflammation (2018 Jan 16) 29338747 Exiting the NIEHS site 2018 
Putrescine as indicator of manganese neurotoxicity: Dose-response study in human SH-SY5Y cells.   Fernandes, Jolyn; Chandler, Joshua D; Liu, Ken H; Uppal, Karan; Go, Young-Mi; Jones, Dean P P30ES019776, R01ES023485 Food Chem Toxicol (2018 Jun) 29684492 Exiting the NIEHS site 2018 
Redox Equivalents and Mitochondrial Bioenergetics.   Roede, James R; Go, Young-Mi; Jones, Dean P R01ES023485, T32ES012870 Methods Mol Biol (2018) 29851002 Exiting the NIEHS site 2018 
Selenium at the redox interface of the genome, metabolome and exposome.   Fernandes, Jolyn; Hu, Xin; Ryan Smith, M; Go, Young-Mi; Jones, Dean P R01ES023485 Free Radic Biol Med (2018 11 01) 29883789 Exiting the NIEHS site 2018 
Selenium Supplementation Alters Hepatic Energy and Fatty Acid Metabolism in Mice.   Hu, Xin; Chandler, Joshua D; Orr, Michael L; Hao, Li; Liu, Ken; Uppal, Karan; Go, Young-Mi; J ... P30ES019776, R01ES023485 J Nutr (2018 05 01) 29982657 Exiting the NIEHS site 2018 
Selenium supplementation prevents metabolic and transcriptomic responses to cadmium in mouse lung.   Hu, Xin; Chandler, Joshua D; Fernandes, Jolyn; Orr, Michael L; Hao, Li; Uppal, Karan; Neujahr, ... P30ES019776, R01ES023485 Biochim Biophys Acta Gen Subj (2018 Nov) 29656123 Exiting the NIEHS site 2018 
xMWAS: a data-driven integration and differential network analysis tool.   Uppal, Karan; Ma, Chunyu; Go, Young-Mi; Jones, Dean P; Wren, Jonathan P30ES019776, R01ES023485 Bioinformatics (2018 02 15) 29069296 Exiting the NIEHS site 2018 
Cadmium stimulates myofibroblast differentiation and mouse lung fibrosis.   Hu, Xin; Fernandes, Jolyn; Jones, Dean P; Go, Young-Mi R01ES023485 Toxicology (2017 05 15) 28341147 Exiting the NIEHS site 2017 
From the Cover: Manganese Stimulates Mitochondrial H2O2 Production in SH-SY5Y Human Neuroblastoma Ce ...   Fernandes, Jolyn; Hao, Li; Bijli, Kaiser M; Chandler, Joshua D; Orr, Michael; Hu, Xin; Jones, ... P30ES019776, R01ES023485 Toxicol Sci (2017 01) 27701121 Exiting the NIEHS site 2017 
Redox dynamics of manganese as a mitochondrial life-death switch.   Smith, Matthew Ryan; Fernandes, Jolyn; Go, Young-Mi; Jones, Dean P R01ES023485 Biochem Biophys Res Commun (2017 01 15) 28212723 Exiting the NIEHS site 2017 
Redox theory of aging: implications for health and disease.   Go, Young-Mi; Jones, Dean P P30ES019776, R01ES023485 Clin Sci (Lond) (2017 Jul 15) 28667066 Exiting the NIEHS site 2017 
xMSannotator: An R Package for Network-Based Annotation of High-Resolution Metabolomics Data.   Uppal, Karan; Walker, Douglas I; Jones, Dean P P30ES019776, R01ES023485 Anal Chem (2017 01 17) 27977166 Exiting the NIEHS site 2017 
Yale school of public health symposium on lifetime exposures and human health: the exposome; summary ...   Johnson, Caroline H; Athersuch, Toby J; Collman, Gwen W; Dhungana, Suraj; Grant, David F; Jones ... P30ES019776, R01ES023485, U2CES026560 Hum Genomics (2017 Dec 08) 29221465 Exiting the NIEHS site 2017 
Computational Metabolomics: A Framework for the Million Metabolome.   Uppal, Karan; Walker, Douglas I; Liu, Ken; Li, Shuzhao; Go, Young-Mi; Jones, Dean P P30ES019776, R01ES023485, T32ES012870, U2CES026560 Chem Res Toxicol (2016 12 19) 27629808 Exiting the NIEHS site 2016 
Deployment-Associated Exposure Surveillance With High-Resolution Metabolomics.   Walker, Douglas I; Mallon, Col Timothy M; Hopke, Philip K; Uppal, Karan; Go, Young-Mi; Rohrbeck ... P30ES019776, R01ES023485, T32ES012870 J Occup Environ Med (2016 08) 27501099 Exiting the NIEHS site 2016 
Exposure Memory and Lung Regeneration.   Go, Young-Mi; Jones, Dean P R01ES023485 Ann Am Thorac Soc (2016 12) 28005420 Exiting the NIEHS site 2016 
Hydrogen peroxide and central redox theory for aerobic life: A tribute to Helmut Sies: Scout, trailb ...   Jones, Dean P P30ES019776, R01ES023485, U2CES026560 Arch Biochem Biophys (2016 Apr 01) 27095208 Exiting the NIEHS site 2016 
Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat d ...   Rao, Anuradha; Kosters, Astrid; Mells, Jamie E; Zhang, Wujuan; Setchell, Kenneth D R; Amanso, ... P30ES019776, R01ES023485 Sci Transl Med (2016 09 21) 27655848 Exiting the NIEHS site 2016 
Low-dose oral cadmium increases airway reactivity and lung neuronal gene expression in mice.   Chandler, Joshua D; Wongtrakool, Cherry; Banton, Sophia A; Li, Shuzhao; Orr, Michael L; Barr, ... R01ES023485, T32ES012870 Physiol Rep (2016 Jul) 27401458 Exiting the NIEHS site 2016 
Metabolic Pathways and Networks Associated With Tobacco Use in Military Personnel.   Jones, Dean P; Walker, Douglas I; Uppal, Karan; Rohrbeck, Patricia; Mallon, Col Timothy M; Go, ... P30ES019776, R01ES023485, T32ES012870 J Occup Environ Med (2016 08) 27501098 Exiting the NIEHS site 2016 
Metabolic pathways of lung inflammation revealed by high-resolution metabolomics (HRM) of H1N1 influ ...   Chandler, Joshua D; Hu, Xin; Ko, Eun-Ju; Park, Soojin; Lee, Young-Tae; Orr, Michael; Fernandes ... R01ES023485 Am J Physiol Regul Integr Comp Physiol (2016 11 01) 27558316 Exiting the NIEHS site 2016 
Metabolomics and Mycobacterial Disease: Don't Forget the Bioinformatics.   Collins, Jeffrey M; Kempker, Russell R; Ziegler, Thomas R; Blumberg, Henry M; Jones, Dean P P30ES019776, R01ES023485, T32ES012870 Ann Am Thorac Soc (2016 Jan) 26730872 Exiting the NIEHS site 2016 
Nuclear Thioredoxin-1 Overexpression Attenuates Alcohol-Mediated Nrf2 Signaling and Lung Fibrosis.   Sueblinvong, Viranuj; Mills, Stephen T; Neujahr, David C; Go, Young-Mi; Jones, Dean P; Guidot, ... R01ES023485 Alcohol Clin Exp Res (2016 09) 27436123 Exiting the NIEHS site 2016 
Sequencing the exposome: A call to action.   Jones, Dean P P30ES019776, R01ES023485, T32ES012870 Toxicol Rep (2016) 26722641 Exiting the NIEHS site 2016 
Anticancer therapeutic potential of Mn porphyrin/ascorbate system.   Tovmasyan, Artak; Sampaio, Romulo S; Boss, Mary-Keara; Bueno-Janice, Jacqueline C; Bader, Bader ... R01ES023485 Free Radic Biol Med (2015 Dec) 26496207 Exiting the NIEHS site 2015 
Disturbed flow induces systemic changes in metabolites in mouse plasma: a metabolomics study using A ...   Go, Young-Mi; Kim, Chan Woo; Walker, Douglas I; Kang, Dong Won; Kumar, Sandeep; Orr, Michael; ... R01ES023485 Am J Physiol Regul Integr Comp Physiol (2015 Jan 01) 25377480 Exiting the NIEHS site 2015 
Low-Dose Cadmium Causes Metabolic and Genetic Dysregulation Associated With Fatty Liver Disease in M ...   Go, Young-Mi; Sutliff, Roy L; Chandler, Joshua D; Khalidur, Rahman; Kang, Bum-Yong; Anania, Fr ... P30ES019776, R01ES023485, T32ES012870 Toxicol Sci (2015 Oct) 26187450 Exiting the NIEHS site 2015 
Metabolic Characterization of the Common Marmoset (Callithrix jacchus).   Go, Young-Mi; Liang, Yongliang; Uppal, Karan; Soltow, Quinlyn A; Promislow, Daniel E L; Wachtma ... P30ES019776, R01ES023485, T32ES012870 PLoS One (2015) 26581102 Exiting the NIEHS site 2015 
Metabolome-wide association study of phenylalanine in plasma of common marmosets.   Go, Young-Mi; Walker, Douglas I; Soltow, Quinlyn A; Uppal, Karan; Wachtman, Lynn M; Strobel, F ... P30ES019776, R01ES023485, T32ES012870 Amino Acids (2015 Mar) 25526869 Exiting the NIEHS site 2015 
Metabolome-Wide Association Study of Primary Open Angle Glaucoma.   Burgess, L Goodwin; Uppal, Karan; Walker, Douglas I; Roberson, Rachel M; Tran, ViLinh; Parks, ... P30ES019776, R01ES023485, T32ES012870 Invest Ophthalmol Vis Sci (2015 Jul) 26230767 Exiting the NIEHS site 2015 
Redox theory of aging.   Jones, Dean P P30ES019776, R01ES023485, T32ES012870 Redox Biol (2015 Aug) 25863726 Exiting the NIEHS site 2015 
Reference Standardization for Mass Spectrometry and High-resolution Metabolomics Applications to Exp ...   Go, Young-Mi; Walker, Douglas I; Liang, Yongliang; Uppal, Karan; Soltow, Quinlyn A; Tran, ViLi ... P30ES019776, R01ES023485, T32ES012870 Toxicol Sci (2015 Dec) 26358001 Exiting the NIEHS site 2015 
The cysteine proteome.   Go, Young-Mi; Chandler, Joshua D; Jones, Dean P P30ES019776, R01ES023485, T32ES012870 Free Radic Biol Med (2015 Jul) 25843657 Exiting the NIEHS site 2015 
The Redox Code.   Jones, Dean P; Sies, Helmut P30ES019776, R01ES023485, T32ES012870 Antioxid Redox Signal (2015 Sep 20) 25891126 Exiting the NIEHS site 2015 
Disturbed flow enhances inflammatory signaling and atherogenesis by increasing thioredoxin-1 level i ...   Go, Young-Mi; Son, Dong Ju; Park, Heonyong; Orr, Michael; Hao, Li; Takabe, Wakako; Kumar, San ... R01ES023485 PLoS One (2014) 25265386 Exiting the NIEHS site 2014 
Mitochondrial metabolomics using high-resolution Fourier-transform mass spectrometry.   Go, Young-Mi; Uppal, Karan; Walker, Douglas I; Tran, ViLinh; Dury, Lauriane; Strobel, Frederic ... R01ES023485, T32ES012870 Methods Mol Biol (2014) 25270922 Exiting the NIEHS site 2014 
Transcriptome-metabolome wide association study (TMWAS) of maneb and paraquat neurotoxicity reveals ...   Roede, James R; Uppal, Karan; Park, Youngja; Tran, ViLinh; Jones, Dean P P30ES019776, R01ES023485 Toxicol Rep (2014) 27722094 Exiting the NIEHS site 2014 
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