Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Internet Explorer is no longer a supported browser.

This website may not display properly with Internet Explorer. For the best experience, please use a more recent browser such as the latest versions of Google Chrome, Microsoft Edge, and/or Mozilla Firefox. Thank you.

Your Environment. Your Health.

Who We Fund: Publication Detail

PI: Chapkin, Robert Stephen
Institution: Texas A&M Agrilife Research
Grant Number: R01ES025713

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 18 publications
Export to Excel (
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Loss of Aryl Hydrocarbon Receptor Promotes Colon Tumorigenesis in ApcS580/+; KrasG12D/+ Mice.   Han, Huajun; Davidson, Laurie A; Hensel, Martha; Yoon, Grace; Landrock, Kerstin; Allred, Clint ... P30ES029067, R01ES025713 Mol Cancer Res (2021 Jan 25) 33495399 Exiting the NIEHS site 2021 
Ah receptor ligands and their impacts on gut resilience: structure-activity effects.   Safe, Stephen; Jayaraman, Arul; Chapkin, Robert S R01ES025713 Crit Rev Toxicol (2020 07) 32597352 Exiting the NIEHS site 2020 
Aryl Hydrocarbon Receptor (AHR) Ligands as Selective AHR Modulators (SAhRMs).   Safe, Stephen; Jin, Un-Ho; Park, Hyejin; Chapkin, Robert S; Jayaraman, Arul R01ES025713 Int J Mol Sci (2020 Sep 11) 32932962 Exiting the NIEHS site 2020 
Effect of diet and intestinal AhR expression on fecal microbiome and metabolomic profiles.   Yang, Fang; DeLuca, Jennifer A A; Menon, Rani; Garcia-Vilarato, Erika; Callaway, Evelyn; Landro ... R01ES025713 Microb Cell Fact (2020 Nov 30) 33256731 Exiting the NIEHS site 2020 
Effects of high-fat diet and intestinal aryl hydrocarbon receptor deletion on colon carcinogenesis.   Garcia-Villatoro, Erika L; DeLuca, Jennifer A A; Callaway, Evelyn S; Allred, Kimberly F; Davidso ... P30ES029067, R01ES025713 Am J Physiol Gastrointest Liver Physiol (2020 03 01) 31905023 Exiting the NIEHS site 2020 
Loss of aryl hydrocarbon receptor potentiates FoxM1 signaling to enhance self-renewal of colonic ste ...   Han, Huajun; Davidson, Laurie A; Fan, Yang-Yi; Goldsby, Jennifer S; Yoon, Grace; Jin, Un-Ho; W ... R01ES025713 EMBO J (2020 Oct 01) 32915464 Exiting the NIEHS site 2020 
Nuclear receptor 4A2 (NR4A2) is a druggable target for glioblastomas.   Karki, Keshav; Li, Xi; Jin, Un-Ho; Mohankumar, Kumaravel; Zarei, Mahsa; Michelhaugh, Sharon K; ... P30ES029067, R01ES021656, R01ES025713, T32ES026568 J Neurooncol (2020 Jan) 31754919 Exiting the NIEHS site 2020 
Establishment of a multicomponent dietary bioactive human equivalent dose to delete damaged Lgr5+ st ...   Kim, Eunjoo; Wright, Gus A; Zoh, Roger S; Patil, Bhimanagouda S; Jayaprakasha, Guddadarangavvan ... R01ES025713 Eur J Cancer Prev (2019 09) 30234553 Exiting the NIEHS site 2019 
Isoflavones as Ah Receptor Agonists in Colon-Derived Cell Lines: Structure-Activity Relationships.   Park, Hyejin; Jin, Un-Ho; Orr, Asuka A; Echegaray, Stephanie P; Davidson, Laurie A; Allred, Cl ... P30ES029067, R01ES025713, R21ES029607 Chem Res Toxicol (2019 11 18) 31621310 Exiting the NIEHS site 2019 
The aryl hydrocarbon receptor is a tumor suppressor-like gene in glioblastoma.   Jin, Un-Ho; Karki, Keshav; Cheng, Yating; Michelhaugh, Sharon K; Mittal, Sandeep; Safe, Stephe ... R01ES025713, T32ES026568 J Biol Chem (2019 07 19) 31171720 Exiting the NIEHS site 2019 
Aryl Hydrocarbon Receptor (AhR) Ligands as Selective AhR Modulators: Genomic Studies.   Safe, Stephen; Han, Huajun; Goldsby, Jennifer; Mohankumar, Kumaravel; Chapkin, Robert S R01ES025713 Curr Opin Toxicol (2018 Oct-Dec) 31453421 Exiting the NIEHS site 2018 
Compensatory Expression of Nur77 and Nurr1 Regulates NF-κB-Dependent Inflammatory Signaling in Astro ...   Popichak, Katriana A; Hammond, Sean L; Moreno, Julie A; Afzali, Maryam F; Backos, Donald S; Sla ... R01ES021656, R01ES025713 Mol Pharmacol (2018 10) 30111648 Exiting the NIEHS site 2018 
Structure-Dependent Modulation of Aryl Hydrocarbon Receptor-Mediated Activities by Flavonoids.   Jin, Un-Ho; Park, Hyejin; Li, Xi; Davidson, Laurie A; Allred, Clinton; Patil, Bhimanagouda; Ja ... R01ES025713 Toxicol Sci (2018 07 01) 29584932 Exiting the NIEHS site 2018 
The Nurr1 Ligand,1,1-bis(3'-Indolyl)-1-(p-Chlorophenyl)Methane, Modulates Glial Reactivity and Is Ne ...   Hammond, Sean L; Popichak, Katriana A; Li, Xi; Hunt, Lindsay G; Richman, Evan H; Damale, Prana ... R01ES021656, R01ES025713 J Pharmacol Exp Ther (2018 06) 29626009 Exiting the NIEHS site 2018 
Editor's Highlight: Microbial-Derived 1,4-Dihydroxy-2-naphthoic Acid and Related Compounds as Aryl H ...   Cheng, Yating; Jin, Un-Ho; Davidson, Laurie A; Chapkin, Robert S; Jayaraman, Arul; Tamamis, Ph ... R01ES007685, R01ES025713 Toxicol Sci (2017 02) 27837168 Exiting the NIEHS site 2017 
Shaping functional gut microbiota using dietary bioactives to reduce colon cancer risk.   Seidel, Derek V; Azcárate-Peril, M Andrea; Chapkin, Robert S; Turner, Nancy D R01ES025713 Semin Cancer Biol (2017 Oct) 28676459 Exiting the NIEHS site 2017 
Short Chain Fatty Acids Enhance Aryl Hydrocarbon (Ah) Responsiveness in Mouse Colonocytes and Caco-2 ...   Jin, Un-Ho; Cheng, Yating; Park, Hyejin; Davidson, Laurie A; Callaway, Evelyn S; Chapkin, Robe ... R01ES025713 Sci Rep (2017 08 31) 28860561 Exiting the NIEHS site 2017 
The Aryl Hydrocarbon Receptor (AhR) as a Drug Target for Cancer Chemotherapy.   Safe, Stephen; Cheng, Yating; Jin, Un-Ho R01ES025713 Curr Opin Toxicol (2017 Feb) 28459113 Exiting the NIEHS site 2017 
to Top