Project Title: | MOLECULAR CLOCK DYSFUNCTION IN LUNG CELLULAR SENESCENCE BY ENVIRONMENTAL TOBACCO SMOKE |
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PI: | Rahman, Irfan |
Institution: | University Of Rochester |
Grant Number: | R01ES029177 |
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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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Environmental tobacco smoke exposure exaggerates bleomycin-induced collagen overexpression during pu ... | Wang, Qixin; Goracci, Chiara; Sundar, Isaac Kirubakaran; Rahman, Irfan | R01ES029177 | J Inflamm (Lond) (2024 Mar 20) | 38509574 | 2024 |
Circadian clock molecule REV-ERBα regulates lung fibrotic progression through collagen stabilization ... | Wang, Qixin; Sundar, Isaac Kirubakaran; Lucas, Joseph H; Park, Jun-Gyu; Nogales, Aitor; Martine ... | R01ES029177 | Nat Commun (2023 Mar 09) | 36894533 | 2023 |
Clearance of senescent cells reverts the cigarette smoke-induced lung senescence and airspace enlarg ... | Kaur, Gagandeep; Muthumalage, Thivanka; Rahman, Irfan | R01ES029177 | Aging Cell (2023 Jul) | 37078230 | 2023 |
Environmental tobacco smoke exposure exaggerates bleomycin- induced collagen overexpression during p ... | Wang, Qixin; Goracci, Chiara; Sundar, Isaac Kirubakaran; Rahman, Irfan | R01ES029177 | Res Sq (2023 Oct 10) | 37886473 | 2023 |
Impact of aging on immune function in the pathogenesis of pulmonary diseases: potential for therapeu ... | Shaikh, Sadiya Bi; Goracci, Chiara; Tjitropranoto, Ariel; Rahman, Irfan | R01ES029177 | Expert Rev Respir Med (2023 May) | 37078192 | 2023 |
Circadian clock-based therapeutics in chronic pulmonary diseases. | Giri, Allan; Rahman, Irfan; Sundar, Isaac Kirubakaran | R01ES029177 | Trends Pharmacol Sci (2022 Dec) | 36302705 | 2022 |
Circadian molecular clock disruption in chronic pulmonary diseases. | Giri, Allan; Wang, Qixin; Rahman, Irfan; Sundar, Isaac Kirubakaran | R01ES029177 | Trends Mol Med (2022 Jun) | 35508604 | 2022 |
Dysregulation of mitochondrial complexes and dynamics by chronic cigarette smoke exposure Utilizing ... | Wang, Qixin; Unwalla, Hoshang; Rahman, Irfan | R01ES029177, R21ES032159 | Mitochondrion (2022 Mar) | 35032706 | 2022 |
Molecular clock REV-ERBα regulates cigarette smoke-induced pulmonary inflammation and epithelial-mes ... | Wang, Qixin; Sundar, Isaac K; Lucas, Joseph H; Muthumalage, Thivanka; Rahman, Irfan | R01ES029177 | JCI Insight (2021 06 22) | 34014841 | 2021 |
Role of inner mitochondrial protein OPA1 in mitochondrial dysfunction by tobacco smoking and in the ... | Maremanda, Krishna Prahlad; Sundar, Isaac Kirubakaran; Rahman, Irfan | R01ES029177 | Redox Biol (2021 Sep) | 34214709 | 2021 |
Age-dependent assessment of genes involved in cellular senescence, telomere and mitochondrial pathwa ... | Maremanda, Krishna P; Sundar, Isaac K; Li, Dongmei; Rahman, Irfan | R01ES029177 | Res Sq (2020 Jun 15) | 32702724 | 2020 |
Inflammatory biomarkers and growth factors in saliva and gingival crevicular fluid of e-cigarette us ... | Ye, Dongxia; Gajendra, Sangeeta; Lawyer, Gina; Jadeja, Neelam; Pishey, Deepa; Pathagunti, Srin ... | R01ES029177 | J Periodontol (2020 10) | 32052441 | 2020 |
Pod-based menthol and tobacco flavored e-cigarettes cause mitochondrial dysfunction in lung epitheli ... | Lamb, Thomas; Muthumalage, Thivanka; Rahman, Irfan | R01ES029177, T32ES007026 | Toxicol Lett (2020 Oct 15) | 32783911 | 2020 |
SARS-CoV-2 COVID-19 susceptibility and lung inflammatory storm by smoking and vaping. | Kaur, Gagandeep; Lungarella, Giuseppe; Rahman, Irfan | R01ES029177 | J Inflamm (Lond) (2020) | 32528233 | 2020 |
Cannabidiol differentially regulates basal and LPS-induced inflammatory responses in macrophages, lu ... | Muthumalage, Thivanka; Rahman, Irfan | P30ES001247, R01ES029177, T32ES007026 | Toxicol Appl Pharmacol (2019 Nov 01) | 31437494 | 2019 |
Dysregulated repair and inflammatory responses by e-cigarette-derived inhaled nicotine and humectant ... | Wang, Qixin; Khan, Naushad Ahmad; Muthumalage, Thivanka; Lawyer, Gina R; McDonough, Samantha R; ... | R01ES029177 | FASEB Bioadv (2019 Oct) | 31825014 | 2019 |
Mitochondrial dysfunction is associated with Miro1 reduction in lung epithelial cells by cigarette s ... | Sundar, Isaac K; Maremanda, Krishna P; Rahman, Irfan | R01ES029177 | Toxicol Lett (2019 Dec 15) | 31593750 | 2019 |
Protective role of mesenchymal stem cells and mesenchymal stem cell-derived exosomes in cigarette sm ... | Maremanda, Krishna Prahlad; Sundar, Isaac Kirubakaran; Rahman, Irfan | R01ES029177 | Toxicol Appl Pharmacol (2019 12 15) | 31678243 | 2019 |
Mechanisms of toxicity and biomarkers of flavoring and flavor enhancing chemicals in emerging tobacc ... | Kaur, Gurjot; Muthumalage, Thivanka; Rahman, Irfan | P30ES001247, R01ES029177, T32ES007026 | Toxicol Lett (2018 May 15) | 29481849 | 2018 |