Title: Heritable variation at the chromosome 21 gene ERG is associated with acute lymphoblastic leukemia risk in children with and without Down syndrome.

Authors: de Smith, Adam J; Walsh, Kyle M; Morimoto, Libby M; Francis, Stephen S; Hansen, Helen M; Jeon, Soyoung; Gonseth, Semira; Chen, Minhui; Sun, Hanxiao; Luna-Fineman, Sandra; Antillón, Federico; Girón, Verónica; Kang, Alice Y; Smirnov, Ivan; Shao, Xiaorong; Whitehead, Todd P; Barcellos, Lisa F; Jolly, Kent W; Healy, Jasmine; Laverdière, Caroline; Sinnett, Daniel; Taub, Jeffrey W; Birch, Jillian M; Thompson, Pamela D; Pombo-de-Oliveira, Maria S; Spector, Logan G; DeWan, Andrew T; Mueller, Beth A; Chiang, Charleston; Metayer, Catherine; Ma, Xiaomei; Wiemels, Joseph L

Published In Leukemia, (2019 Nov)

Abstract: Abstract not available from PubMed.

PubMed ID: 31296947

MeSH Terms: Adolescent; California/epidemiology; California/ethnology; Case-Control Studies; Child; Child, Preschool; Chromosomes, Human, Pair 21/genetics; Down Syndrome/complications; Down Syndrome/ethnology; Down Syndrome/genetics*; Female; Genetic Predisposition to Disease; Genome-Wide Association Study; Guatemala/epidemiology; Guatemala/ethnology; Haplotypes; Hispanic or Latino; Humans; Infant; Infant, Newborn; Male; Polymorphism, Single Nucleotide*; Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications; Precursor Cell Lymphoblastic Leukemia-Lymphoma/ethnology; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics*; Principal Component Analysis; Risk Factors; Transcriptional Regulator ERG/genetics