Title: The Neurodevelopment of Autism from Infancy Through Toddlerhood.
Authors: Girault, Jessica B; Piven, Joseph
Published In Neuroimaging Clin N Am, (2020 Feb)
Abstract: Autism spectrum disorder (ASD) emerges during early childhood and is marked by a relatively narrow window in which infants transition from exhibiting normative behavioral profiles to displaying the defining features of the ASD phenotype in toddlerhood. Prospective brain imaging studies in infants at high familial risk for autism have revealed important insights into the neurobiology and developmental unfolding of ASD. In this article, we review neuroimaging studies of brain development in ASD from birth through toddlerhood, relate these findings to candidate neurobiological mechanisms, and discuss implications for future research and translation to clinical practice.
PubMed ID: 31759576
MeSH Terms: Autism Spectrum Disorder/diagnostic imaging; Autism Spectrum Disorder/pathology*; Brain/diagnostic imaging; Brain/growth & development*; Brain/pathology*; Child, Preschool; Humans; Infant; Infant, Newborn; Magnetic Resonance Imaging; Neuroimaging/methods*; Prognosis; Prospective Studies