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Publication Detail

Title: lifetime exposure to traffic-related air pollution and symptoms of depression and anxiety at age 12 years.

Authors: Yolton, Kimberly; Khoury, Jane C; Burkle, Jeffrey; LeMasters, Grace; Cecil, Kim; Ryan, Patrick

Published In Environ Res, (2019 06)

Abstract: While air pollution has been associated with depression and anxiety in adults, its impact on childhood mental health is understudied.We examined lifetime exposure to traffic-related air pollution (TRAP) and symptoms of depression and anxiety at age 12 years in the Cincinnati Childhood Allergy and Air Pollution Study cohort.We estimated exposure to elemental carbon attributable to traffic (ECAT), a surrogate of diesel exhaust, at birth, age 12 years, and average exposure throughout childhood, using a validated land use regression model. We assessed depression and anxiety at age 12 years by parent report with the Behavior Assessment System for Children-2, and by child report with the Child Depression Inventory-2 (CDI-2) and the Spence Children's Anxiety Scale (SCAS). Associations between TRAP at birth, age 12 years, and childhood average and mental health outcomes were estimated using linear regression models adjusting for covariates including parent depression, secondhand smoke exposure, race, household income, and others.Exposure to ECAT was not significantly associated with parent-reported depression or anxiety. However, exposure to ECAT at birth was associated with increased child-reported depression and anxiety. Each 0.25 µg/m3 increase in ECAT was associated with a 3.5 point increase (95% CI 1.6-5.5) in CDI-2 scores and 2.3 point increase (95% CI 0.8-3.9) in SCAS total anxiety scores. We observed similar associations between average childhood ECAT exposures but not for concurrent exposures at age 12.TRAP exposure during early life and across childhood was significantly associated with self-reported depression and anxiety symptoms in children. The negative impact of air pollution on mental health previously reported among adults may also be present during childhood.

PubMed ID: 30925441 Exiting the NIEHS site

MeSH Terms: Adult; Air Pollutants*; Air Pollution/statistics & numerical data*; Anxiety/epidemiology*; Child; Depression/epidemiology*; Environmental Exposure/statistics & numerical data*; Humans; Vehicle Emissions/analysis*

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