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Publication Detail

Title: A longitudinal study of chest radiographic changes of workers in the refractory ceramic fiber industry.

Authors: Lockey, James E; LeMasters, Grace K; Levin, Linda; Rice, Carol; Yiin, James; Reutman, Susan; Papes, Diane

Published In Chest, (2002 Jun)

Abstract: This industry-wide longitudinal study examines chest radiographic changes of workers manufacturing refractory ceramic fibers (RCF).Chest radiographs were obtained every 3 years and were interpreted using the 1980 International Labour Organization classification for pneumoconiosis. Three exposure metrics were calculated: duration and latency in a production job, and cumulative exposure (fiber-months per cubic centimeter).The radiographic survey included 625 current workers at five manufacturing sites and 383 former workers at two of the five sites.Pleural changes were seen in 27 workers (2.7%). Of workers with > 20 years of latency from initial production job or 20 years of duration in a production job, 16 workers (8.0%) and 5 workers (8.1%) demonstrated pleural changes, respectively. Results from the cumulative exposure analysis (> 135 fiber-months per cubic centimeter) demonstrated a significant elevated odds ratio (OR) of 6.0 (95% confidence interval [CI], 1.4 to 31.0). The incidence of irregular opacities at profusion categories > or = 1/0 was similar to other nonspecified dust-exposed worker populations at 1.0%, and showed a nonsignificant elevated OR in regard to cumulative fiber exposure of 4.7 (95% CI, 0.97 to 23.5).RCF are significantly associated with pleural changes that were predominantly pleural plaques, but have not resulted in a statistically significant increase in interstitial changes.

PubMed ID: 12065376 Exiting the NIEHS site

MeSH Terms: Adult; Ceramics/adverse effects*; Female; Humans; Longitudinal Studies; Lung Diseases/diagnostic imaging*; Lung Diseases/etiology; Male; Middle Aged; Mineral Fibers/adverse effects*; Occupational Diseases/diagnostic imaging*; Occupational Diseases/etiology; Prospective Studies; Radiography

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