| Project Title: | MOLECULAR AND CELLULAR BASIS OF PCB DEVELOPMENTAL NEUROTOXICITY |
|---|---|
| PI: | Lein, Pamela J |
| Institution: | University Of California At Davis |
| Grant Number: | R01ES014901 |
These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| Assessing CaMPARI as new approach methodology for evaluating neurotoxicity. | Biechele-Speziale, Dana; Camarillo, Manuel; Martin, Nathan R; Biechele-Speziale, John; Lein, Pa ... | P30ES023513, R01ES014901, R01ES030109 | Neurotoxicology (2023 Jul) |
37244562
|
2023 |
| Detection of Transgene Location in the CYP2A13/2B6/2F1-transgenic Mouse Model using Optical Genome M ... | Ding, Xinxin; Han, John; Van Winkle, Laura S; Zhang, Qing-Yu | P30ES006694, P42ES004940, R01ES014901, R01ES020867 | Drug Metab Dispos (2023 Jan) |
36273825
|
2023 |
| Developmental Neurotoxicity Screen of Psychedelics and Other Drugs of Abuse in Larval Zebrafish (Dan ... | Tombari, Robert J; Mundy, Paige C; Morales, Kelly M; Dunlap, Lee E; Olson, David E; Lein, Pame ... | P30ES023513, R01ES014901 | ACS Chem Neurosci (2023 Mar 01) |
36753397
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2023 |
| Disposition and metabolomic effects of 2,2',5,5'-tetrachlorobiphenyl in female rats following intrap ... | Bullert, Amanda; Li, Xueshu; Chunyun, Zhang; Lee, Kendra; Pulliam, Casey F; Cagle, Brianna S; ... | P30ES005605, P42ES013661, R01ES014901, R01ES031098 | Environ Toxicol Pharmacol (2023 Sep) |
37572994
|
2023 |
| Disposition and Metabolomic Effects of 2,2',5,5'-Tetrachlorobiphenyl in Female Rats Following Intrap ... | Bullert, Amanda; Li, Xueshu; Zhang, Chunyun; Lee, Kendra; Pulliam, Casey F; Cagle, Brianna S; ... | P30ES005605, P42ES013661, R01ES014901, R01ES031098 | bioRxiv (2023 Aug 09) |
37609242
|
2023 |
| Enantiomeric Fractions Reveal Differences in the Atropselective Disposition of 2,2',3,5',6-Pentachlo ... | Li, Xueshu; Bullert, Amanda J; Han, Weiguo; Yang, Weizhu; Zhang, Qing-Yu; Ding, Xinxin; Lehmle ... | P30ES005605, P30ES006694, P42ES013661, R01ES014901, R01ES020867, R01ES031098 | Chem Res Toxicol (2023 Aug 21) |
37467352
|
2023 |
| Gene×environment interactions in autism spectrum disorders. | Keil-Stietz, Kimberly; Lein, Pamela J | P30ES023513, R00ES029537, R01ES014901 | Curr Top Dev Biol (2023) |
36707213
|
2023 |
| Rebuttal to Correspondence on "Machine Learning-Assisted Identification and Quantification of Hydrox ... | Zhang, Chun-Yun; Li, Xueshu; Keil Stietz, Kimberly P; Sethi, Sunjay; Yang, Weizhu; Marek, Rach ... | P30ES005605, P30ES023513, P42ES013661, R01ES014901, R01ES031098 | Environ Sci Technol (2023 Apr 18) |
37017328
|
2023 |
| Assessing cytochrome P450 function using genetically engineered mouse models. | Hannon, Sarrah L; Ding, Xinxin | F31ES034268, P30ES006694, P42ES004940, R01ES014901, R01ES020867, R01ES031529, T32ES007091 | Adv Pharmacol (2022) |
35953157
|
2022 |
| Machine Learning-Assisted Identification and Quantification of Hydroxylated Metabolites of Polychlor ... | Zhang, Chun-Yun; Li, Xueshu; Keil Stietz, Kimberly P; Sethi, Sunjay; Yang, Weizhu; Marek, Rach ... | P30ES005605, P30ES023513, P42ES013661, R01ES014901, R01ES031098 | Environ Sci Technol (2022 Sep 20) |
36047920
|
2022 |
| Metabolism of 3-Chlorobiphenyl (PCB 2) in a Human-Relevant Cell Line: Evidence of Dechlorinated Meta ... | Zhang, Chun-Yun; Li, Xueshu; Flor, Susanne; Ruiz, Patricia; Kruve, Anneli; Ludewig, Gabriele; ... | P30ES005605, P42ES013661, R01ES014901, R01ES031098 | Environ Sci Technol (2022 Sep 06) |
35994059
|
2022 |
| Probing the Role of CYP2 Enzymes in the Atropselective Metabolism of Polychlorinated Biphenyls Using ... | Lehmler, Hans-Joachim; Uwimana, Eric; Dean, Laura E; Kovalchuk, Nataliia; Zhang, Qing-Yu; Ding, ... | P30ES005605, P42ES013661, R01ES014901, R01ES020867 | Chem Res Toxicol (2022 Dec 19) |
36473170
|
2022 |
| The disposition of polychlorinated biphenyls (PCBs) differs between germ-free and conventional mice. | Li, Xueshu; Lim, Joe Jongpyo; Wang, Kai; Prasad, Bhagwat; Bhatt, Deepak K; Cui, Julia Yue; Leh ... | P30ES005605, P30ES007033, P42ES013661, R01ES014901, R01ES031098, T32ES007032 | Environ Toxicol Pharmacol (2022 May) |
35331926
|
2022 |
| Triiodothyronine or Antioxidants Block the Inhibitory Effects of BDE-47 and BDE-49 on Axonal Growth ... | Chen, Hao; Carty, Rhianna K; Bautista, Adrienne C; Hayakawa, Keri A; Lein, Pamela J | P30ES023513, P42ES004699, R01ES014901, T32ES007059 | Toxics (2022 Feb 18) |
35202279
|
2022 |
| Characterization of the Metabolic Pathways of 4-Chlorobiphenyl (PCB3) in HepG2 Cells Using the Metab ... | Zhang, Chun-Yun; Flor, Susanne; Ruiz, Patricia; Ludewig, Gabriele; Lehmler, Hans-Joachim | P30ES005605, P42ES013661, R01ES014901, R01ES031098 | Environ Sci Technol (2021 07 06) |
34125531
|
2021 |
| Developmental Exposure to a Human-Relevant Polychlorinated Biphenyl Mixture Causes Behavioral Phenot ... | Sethi, Sunjay; Keil Stietz, Kimberly P; Valenzuela, Anthony E; Klocke, Carolyn R; Silverman, Ji ... | P30ES023513, P42ES013661, R00ES029537, R01ES014901, T32ES007059 | Front Neurosci (2021) |
34938155
|
2021 |
| Disposition of PCB 11 in Mice Following Acute Oral Exposure. | Zhang, Chun-Yun; Klocke, Carolyn R; Lein, Pamela J; Lehmler, Hans-Joachim | P30ES005605, P42ES013661, R01ES014901, R01ES029213, R01ES029213, R01ES031098 | Chem Res Toxicol (2021 04 19) |
33734669
|
2021 |
| In utero and lactational PCB exposure drives anatomic changes in the juvenile mouse bladder. | Keil Stietz, Kimberly P; Kennedy, Conner L; Sethi, Sunjay; Valenzuela, Anthony; Nunez, Alexandr ... | P30ES005605, P30ES023513, P42ES013661, R00ES029537, R01ES014901, R01ES029213, R01ES029213, T32ES007015, T32ES007059 | Curr Res Toxicol (2021) |
34337439
|
2021 |
| Nontarget analysis reveals gut microbiome-dependent differences in the fecal PCB metabolite profiles ... | Li, Xueshu; Liu, Yanna; Martin, Jonathan W; Cui, Julia Yue; Lehmler, Hans-Joachim | P30ES005605, P30ES007033, P42ES013661, R01ES014901, R01ES030197, R01ES031098 | Environ Pollut (2021 Jan 01) |
33032095
|
2021 |
| Sex and Genotype Modulate the Dendritic Effects of Developmental Exposure to a Human-Relevant Polych ... | Keil Stietz, Kimberly P; Sethi, Sunjay; Klocke, Carolyn R; de Ruyter, Tryssa E; Wilson, Machell ... | P30ES023513, P42ES013661, R00ES029537, R01ES014901, R01ES029213, R01ES029213, T32ES007059 | Front Neurosci (2021) |
34924936
|
2021 |
| The Bladder Is a Novel Target of Developmental Polychlorinated Biphenyl Exposure Linked to Increased ... | Kennedy, Conner L; Spiegelhoff, Audrey; Wang, Kathy; Lavery, Thomas; Nunez, Alexandra; Manuel, ... | P30ES005605, P42ES013661, R00ES029537, R01ES014901, T32ES007015 | Toxics (2021 Sep 08) |
34564365
|
2021 |
| The Effects of Polychlorinated Biphenyl Exposure During Adolescence on the Nervous System: A Compreh ... | Bullert, Amanda J; Doorn, Jonathan A; Stevens, Hanna E; Lehmler, Hans-Joachim | P30ES005605, P42ES013661, R01ES014901 | Chem Res Toxicol (2021 Sep 20) |
34491731
|
2021 |
| 3,3'-Dichlorobiphenyl Is Metabolized to a Complex Mixture of Oxidative Metabolites, Including Novel ... | Zhang, Chun-Yun; Flor, Susanne; Ruiz, Patricia; Dhakal, Ram; Hu, Xin; Teesch, Lynn M; Ludewig, ... | P30ES005605, P30ES019776, P42ES013661, R01ES014901 | Environ Sci Technol (2020 Oct 06) |
32910851
|
2020 |
| Automated high content image analysis of dendritic arborization in primary mouse hippocampal and rat ... | Schmuck, Martin R; Keil, Kimberly P; Sethi, Sunjay; Morgan, Rhianna K; Lein, Pamela J | P30ES005605, P30ES023513, R00ES029537, R01ES014901, T32ES007059 | J Neurosci Methods (2020 Jul 15) |
32461071
|
2020 |
| Evidence Implicating Non-Dioxin-Like Congeners as the Key Mediators of Polychlorinated Biphenyl (PCB ... | Klocke, Carolyn; Lein, Pamela J | P30ES023513, R01ES014901 | Int J Mol Sci (2020 Feb 04) |
32033061
|
2020 |
| Fatty liver and impaired hepatic metabolism alter the congener-specific distribution of polychlorina ... | Li, Xueshu; Zhang, Chunyun; Wang, Kai; Lehmler, Hans-Joachim | P30ES005605, P42ES013661, R01ES014901, R01ES031098 | Environ Pollut (2020 Nov) |
32712482
|
2020 |
| Human Cerebral Cortex Proteome of Fragile X-Associated Tremor/Ataxia Syndrome. | Holm, Katharine Nichole; Herren, Anthony W; Taylor, Sandra L; Randol, Jamie L; Kim, Kyoungmi; E ... | R01ES014901 | Front Mol Biosci (2020) |
33585555
|
2020 |
| Polychlorinated Biphenyls (PCBs): Risk Factors for Autism Spectrum Disorder? | Panesar, Harmanpreet Kaur; Kennedy, Conner L; Keil Stietz, Kimberly P; Lein, Pamela J | P30ES005605, P30ES023513, R00ES029537, R01ES014901, T32ES007015, T32ES007059 | Toxics (2020 Sep 17) |
32957475
|
2020 |
| Ryanodine Receptor Type 2: A Molecular Target for Dichlorodiphenyltrichloroethane- and Dichlorodiphe ... | Truong, Kim M; Feng, Wei; Pessah, Isaac N | P30ES005605, P42ES004699, R01ES014901 | Toxicol Sci (2020 Nov 01) |
32894766
|
2020 |
| The developmental neurotoxicity of legacy vs. contemporary polychlorinated biphenyls (PCBs): similar ... | Klocke, Carolyn; Sethi, Sunjay; Lein, Pamela J | P30ES005605, P30ES023513, R01ES014901, T32ES007059 | Environ Sci Pollut Res Int (2020 Mar) |
31713823
|
2020 |
| The influence of sex, genotype, and dose on serum and hippocampal cytokine levels in juvenile mice d ... | Matelski, Lauren; Keil Stietz, Kimberly P; Sethi, Sunjay; Taylor, Sandra L; Van de Water, Judy; ... | P30ES005605, P30ES023513, P42ES013661, R00ES029537, R01ES014901, T32ES007059 | Curr Res Toxicol (2020 Jun 10) |
34296199
|
2020 |
| Translational Toxicology in Zebrafish. | Tal, Tamara; Yaghoobi, Bianca; Lein, Pamela J | P30ES005605, P30ES023513, R01ES014901 | Curr Opin Toxicol (2020) |
32656393
|
2020 |
| Commentary: Fc Gamma Receptors are Expressed in the Developing Rat Brain and Activate Downstream Sig ... | Stamou, Marianna; Lein, Pamela J | P30ES005605, P30ES023513, R01ES014901 | J Neurol Neuromedicine (2019) |
31131371
|
2019 |
| Comparative Analyses of the 12 Most Abundant PCB Congeners Detected in Human Maternal Serum for Acti ... | Sethi, Sunjay; Morgan, Rhianna K; Feng, Wei; Lin, Yanping; Li, Xueshu; Luna, Corey; Koch, Mad ... | P30ES005605, P30ES023513, P42ES013661, R01ES014901, T32ES007059 | Environ Sci Technol (2019 04 02) |
30821444
|
2019 |
| Developmental exposure to environmentally relevant concentrations of bifenthrin alters transcription ... | Frank, Daniel F; Brander, Susanne M; Hasenbein, Simone; Harvey, Danielle J; Lein, Pamela J; Gei ... | P30ES005605, P30ES023513, R01ES014901 | Aquat Toxicol (2019 Jan) |
30414561
|
2019 |
| Developmental exposure to polychlorinated biphenyls (PCBs) in the maternal diet causes host-microbe ... | Rude, Kavi M; Pusceddu, Matteo M; Keogh, Ciara E; Sladek, Jessica A; Rabasa, Gonzalo; Miller, ... | P30ES005605, P30ES023513, R00ES029537, R01ES014901, T32ES007059 | Environ Pollut (2019 Oct) |
31336350
|
2019 |
| Genetic mutations in Ca2+ signaling alter dendrite morphology and social approach in juvenile mice. | Keil, Kimberly P; Sethi, Sunjay; Wilson, Machelle D; Silverman, Jill L; Pessah, Isaac N; Lein, ... | P30ES005605, P30ES023513, R01ES014901, T32ES007059 | Genes Brain Behav (2019 Jan) |
30311737
|
2019 |
| Influence of Nanomolar Deltamethrin on the Hallmarks of Primary Cultured Cortical Neuronal Network a ... | Zheng, Jing; Yu, Yiyi; Feng, Wei; Li, Jing; Liu, Ju; Zhang, Chunlei; Dong, Yao; Pessah, Isaa ... | P42ES004699, R01ES014901 | Environ Health Perspect (2019 06) |
31166131
|
2019 |
| Interactions of Dichlorodiphenyltrichloroethane (DDT) and Dichlorodiphenyldichloroethylene (DDE) Wit ... | Truong, Kim M; Cherednichenko, Gennady; Pessah, Isaac N | P42ES004699, R01ES014901 | Toxicol Sci (2019 08 01) |
31127943
|
2019 |
| MicroRNAs are Necessary for BMP-7-induced Dendritic Growth in Cultured Rat Sympathetic Neurons. | Pravoverov, Kristina; Whiting, Katherine; Thapa, Slesha; Bushong, Trevor; Trang, Karen; Lein, ... | P30ES005605, R01ES014901 | Cell Mol Neurobiol (2019 Oct) |
31104181
|
2019 |
| Neurotoxicity of polychlorinated biphenyls and related organohalogens. | Pessah, Isaac N; Lein, Pamela J; Seegal, Richard F; Sagiv, Sharon K | P30ES005605, P42ES004699, R01ES014901 | Acta Neuropathol (2019 Sep) |
30976975
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2019 |
| Polychlorinated biphenyls influence on autism spectrum disorder risk in the MARBLES cohort. | Granillo, Lauren; Sethi, Sunjay; Keil, Kimberly P; Lin, Yanping; Ozonoff, Sally; Iosif, Ana-Ma ... | P30ES005605, P30ES023513, R01ES014901, R01ES029213, R01ES029213, T32ES007059 | Environ Res (2019 Apr) |
30665119
|
2019 |
| Saikosaponin d causes apoptotic death of cultured neocortical neurons by increasing membrane permeab ... | Zheng, Jing; Chen, Juan; Zou, Xiaohan; Zhao, Fang; Guo, Mengqi; Wang, Hongbo; Zhang, Tian; Zh ... | P30ES005605, P42ES004699, R01ES014901 | Neurotoxicology (2019 Jan) |
30458186
|
2019 |
| Sex-Dependent Effects of 2,2',3,5',6-Pentachlorobiphenyl on Dendritic Arborization of Primary Mouse ... | Keil, Kimberly P; Sethi, Sunjay; Lein, Pamela J | P30ES005605, P30ES023513, R01ES014901, T32ES007059 | Toxicol Sci (2019 Mar 01) |
30395321
|
2019 |
| 3,3'-Dichlorobiphenyl (PCB 11) promotes dendritic arborization in primary rat cortical neurons via a ... | Sethi, Sunjay; Keil, Kimberly P; Lein, Pamela J | P30ES005605, P30ES023513, P42ES013661, R01ES014901, T32ES007059 | Arch Toxicol (2018 Nov) |
30225637
|
2018 |
| A Prospective Study of Environmental Exposures and Early Biomarkers in Autism Spectrum Disorder: Des ... | Hertz-Picciotto, Irva; Schmidt, Rebecca J; Walker, Cheryl K; Bennett, Deborah H; Oliver, McKenz ... | P30ES005605, P30ES023513, R01ES014901, R01ES029213, R01ES029213 | Environ Health Perspect (2018 Nov) |
30465702
|
2018 |
| Authentication of synthetic environmental contaminants and their (bio)transformation products in tox ... | Li, Xueshu; Holland, Erika B; Feng, Wei; Zheng, Jing; Dong, Yao; Pessah, Isaac N; Duffel, Mic ... | P30ES005605, P42ES004699, P42ES013661, R01ES014901 | Environ Sci Pollut Res Int (2018 Jun) |
29322390
|
2018 |
| Bifenthrin causes transcriptomic alterations in mTOR and ryanodine receptor-dependent signaling and ... | Frank, Daniel F; Miller, Galen W; Harvey, Danielle J; Brander, Susanne M; Geist, Juergen; Conno ... | P30ES005605, R01ES014901 | Aquat Toxicol (2018 Jul) |
29727771
|
2018 |
| Opportunities and challenges for using the zebrafish to study neuronal connectivity as an endpoint o ... | Miller, Galen W; Chandrasekaran, Vidya; Yaghoobi, Bianca; Lein, Pamela J | P30ES005605, P30ES023513, R01ES014901 | Neurotoxicology (2018 Jul) |
29704525
|
2018 |
| Organohalogens Naturally Biosynthesized in Marine Environments and Produced as Disinfection Byproduc ... | Zheng, Jing; McKinnie, Shaun M K; El Gamal, Abrahim; Feng, Wei; Dong, Yao; Agarwal, Vinayak; F ... | P30ES005605, P42ES004699, R01ES014901 | Environ Sci Technol (2018 May 01) |
29617551
|
2018 |
| PCB 95 promotes dendritic growth in primary rat hippocampal neurons via mTOR-dependent mechanisms. | Keil, Kimberly P; Miller, Galen W; Chen, Hao; Sethi, Sunjay; Schmuck, Martin R; Dhakal, Kiran; ... | P30ES005605, P30ES023513, R01ES014901, T32ES007059 | Arch Toxicol (2018 Oct) |
30132043
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2018 |
| Simultaneous quantification of T4, T3, rT3, 3,5-T2 and 3,3'-T2 in larval zebrafish (Danio rerio) as ... | Chen, Xiaopeng; Walter, Kyla M; Miller, Galen W; Lein, Pamela J; Puschner, Birgit | P30ES005605, R01ES014901, T32ES007059 | Biomed Chromatogr (2018 Jun) |
29314156
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2018 |
| An Extended Structure-Activity Relationship of Nondioxin-Like PCBs Evaluates and Supports Modeling P ... | Holland, Erika B; Feng, Wei; Zheng, Jing; Dong, Yao; Li, Xueshu; Lehmler, Hans-Joachim; Pessah ... | P30ES005605, P42ES004699, P42ES013661, R01ES014901 | Toxicol Sci (2017 Jan) |
27655348
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2017 |
| Calcium dysregulation and Cdk5-ATM pathway involved in a mouse model of fragile X-associated tremor/ ... | Robin, Gaëlle; López, José R; Espinal, Glenda M; Hulsizer, Susan; Hagerman, Paul J; Pessah, Is ... | R01ES014901 | Hum Mol Genet (2017 07 15) |
28444183
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2017 |
| Comparison of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) in the ser ... | Lau, Grace; Walter, Kyla; Kass, Philip; Puschner, Birgit | R01ES014901, T32ES007059 | PeerJ (2017) |
28924500
|
2017 |
| Detection of 3,3'-Dichlorobiphenyl in Human Maternal Plasma and Its Effects on Axonal and Dendritic ... | Sethi, Sunjay; Keil, Kimberly P; Chen, Hao; Hayakawa, Keri; Li, Xueshu; Lin, Yanping; Lehmler, ... | P30ES005605, P30ES023513, P42ES013661, R01ES014901, T32ES007059 | Toxicol Sci (2017 Aug 01) |
28510766
|
2017 |
| Developing and applying the adverse outcome pathway concept for understanding and predicting neuroto ... | Bal-Price, Anna; Lein, Pamela J; Keil, Kimberly P; Sethi, Sunjay; Shafer, Timothy; Barenys, Ma ... | R01ES014901, T32ES007059 | Neurotoxicology (2017 Mar) |
27212452
|
2017 |
| Divergent Mechanisms Leading to Signaling Dysfunction in Embryonic Muscle by Bisphenol A and Tetrabr ... | Zhang, Rui; Pessah, Isaac N | R01ES014901, T32ES007059 | Mol Pharmacol (2017 04) |
28143888
|
2017 |
| Editor's Highlight: Congener-Specific Disposition of Chiral Polychlorinated Biphenyls in Lactating M ... | Kania-Korwel, Izabela; Lukasiewicz, Tracy; Barnhart, Christopher D; Stamou, Marianna; Chung, Ha ... | P30ES005605, P42ES013661, R01ES014901, T32ES007059 | Toxicol Sci (2017 Jul 01) |
28431184
|
2017 |
| Enantioselectivity of 2,2',3,5',6-Pentachlorobiphenyl (PCB 95) Atropisomers toward Ryanodine Recepto ... | Feng, Wei; Zheng, Jing; Robin, Gaëlle; Dong, Yao; Ichikawa, Makoto; Inoue, Yoshihisa; Mori, T ... | P42ES004699, R01ES014901 | Environ Sci Technol (2017 Dec 19) |
29131945
|
2017 |
| From the Cover: BDE-47 and BDE-49 Inhibit Axonal Growth in Primary Rat Hippocampal Neuron-Glia Co-Cu ... | Chen, Hao; Streifel, Karin M; Singh, Vikrant; Yang, Dongren; Mangini, Linley; Wulff, Heike; Le ... | P30ES023513, R01ES014901, T32ES007059 | Toxicol Sci (2017 Apr 01) |
28003438
|
2017 |
| Identification of lipidomic markers of chronic 3,3',4,4',5-pentachlorobiphenyl (PCB 126) exposure in ... | Kania-Korwel, Izabela; Wu, Xianai; Wang, Kai; Lehmler, Hans-Joachim | P30ES005605, P42ES013661, R01ES014901 | Toxicology (2017 09 01) |
28890136
|
2017 |
| In vivo and in vitro sex differences in the dendritic morphology of developing murine hippocampal an ... | Keil, Kimberly P; Sethi, Sunjay; Wilson, Machelle D; Chen, Hao; Lein, Pamela J | R01ES014901, T32ES007059 | Sci Rep (2017 Aug 16) |
28814778
|
2017 |
| Polychlorinated biphenyl and polybrominated diphenyl ether profiles in serum from cattle, sheep, and ... | Sethi, S; Chen, X; Kass, P H; Puschner, B | P42ES004699, R01ES014901, T32ES007059 | Chemosphere (2017 Aug) |
28426942
|
2017 |
| Quantification of Polychlorinated Biphenyls and Polybrominated Diphenyl Ethers in Commercial Cows' M ... | Chen, Xiaopeng; Lin, Yanping; Dang, Katherine; Puschner, Birgit | P30ES023513, P42ES004699, R01ES014901 | PLoS One (2017) |
28085917
|
2017 |
| Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) poten ... | Aschner, Michael; Ceccatelli, Sandra; Daneshian, Mardas; Fritsche, Ellen; Hasiwa, Nina; Hartung ... | R01ES007331, R01ES010563, R01ES014901 | ALTEX (2017) |
27452664
|
2017 |
| Ryanodine receptor and FK506 binding protein 1 in the Atlantic killifish (Fundulus heteroclitus): A ... | Holland, Erika B; Goldstone, Jared V; Pessah, Isaac N; Whitehead, Andrew; Reid, Noah M; Karchne ... | P42ES004699, R01ES014901 | Aquat Toxicol (2017 Nov) |
28942070
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2017 |
| Species and Sex Differences in the Morphogenic Response of Primary Rodent Neurons to 3,3'-Dichlorobi ... | Sethi, Sunjay; Keil, Kimberly P; Lein, Pamela J | P30ES023513, P42ES013661, R01ES014901, T32ES007059 | Toxics (2017 Dec 23) |
29295518
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2017 |
| Transcriptomic profiling of mTOR and ryanodine receptor signaling molecules in developing zebrafish ... | Frank, Daniel F; Miller, Galen W; Connon, Richard E; Geist, Juergen; Lein, Pamela J | R01ES014901 | PeerJ (2017) |
29201571
|
2017 |
| Valid statistical approaches for analyzing sholl data: Mixed effects versus simple linear models. | Wilson, Machelle D; Sethi, Sunjay; Lein, Pamela J; Keil, Kimberly P | P30ES023513, R01ES014901, T32ES007059 | J Neurosci Methods (2017 Mar 01) |
28104486
|
2017 |
| BMP7-induced dendritic growth in sympathetic neurons requires p75(NTR) signaling. | Courter, Lauren A; Shaffo, Frances C; Ghogha, Atefeh; Parrish, Diana J; Lorentz, Christina U; H ... | R01ES014901 | Dev Neurobiol (2016 09) |
26663679
|
2016 |
| Chiral polychlorinated biphenyls: absorption, metabolism and excretion--a review. | Kania-Korwel, Izabela; Lehmler, Hans-Joachim | P30ES005605, P42ES007380, P42ES013661, R01ES014901 | Environ Sci Pollut Res Int (2016 Feb) |
25651810
|
2016 |
| Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, ... | Dunaway, Keith W; Islam, M Saharul; Coulson, Rochelle L; Lopez, S Jesse; Vogel Ciernia, Annie; ... | R01ES014901, T32ES007059 | Cell Rep (2016 Dec 13) |
27974215
|
2016 |
| DNA methylation: a mechanism linking environmental chemical exposures to risk of autism spectrum dis ... | Keil, Kimberly P; Lein, Pamela J | R01ES014901 | Environ Epigenet (2016 Mar) |
27158529
|
2016 |
| Effects of thiol antioxidants on the atropselective oxidation of 2,2',3,3',6,6'-hexachlorobiphenyl ( ... | Wu, Xianai; Lehmler, Hans-Joachim | P30ES005605, P30ES006694, P42ES013661, R01ES014901 | Environ Sci Pollut Res Int (2016 Feb) |
26155892
|
2016 |
| Phenobarbital use and neurological problems in FMR1 premutation carriers. | Saldarriaga, Wilmar; Lein, Pamela; González Teshima, Laura Yuriko; Isaza, Carolina; Rosa, Lina; ... | R01ES014901 | Neurotoxicology (2016 Mar) |
26802682
|
2016 |
| Toxicokinetics of chiral polychlorinated biphenyls across different species--a review. | Kania-Korwel, Izabela; Lehmler, Hans-Joachim | P30ES005605, P42ES013661, R01ES014901 | Environ Sci Pollut Res Int (2016 Feb) |
25824003
|
2016 |
| Effect of pregnancy on the disposition of 2,2',3,5',6-pentachlorobiphenyl (PCB 95) atropisomers and ... | Kania-Korwel, Izabela; Barnhart, Christopher D; Lein, Pamela J; Lehmler, Hans-Joachim | P30ES005605, P42ES004699, P42ES013661, R01ES014901, T32ES007059 | Chem Res Toxicol (2015 Sep 21) |
26271003
|
2015 |
| Expression and function of ryanodine receptor related pathways in PCB tolerant Atlantic killifish (F ... | Fritsch, Erika B; Stegeman, John J; Goldstone, Jared V; Nacci, Diane E; Champlin, Denise; Jayar ... | P42ES004699, R01ES014901 | Aquat Toxicol (2015 Feb) |
25546006
|
2015 |
| Hepatic metabolism affects the atropselective disposition of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB ... | Wu, Xianai; Barnhart, Christopher; Lein, Pamela J; Lehmler, Hans-Joachim | P30ES005605, P30ES006694, P42ES004699, P42ES013661, R01ES014901, T32ES007059 | Environ Sci Technol (2015 Jan 06) |
25420130
|
2015 |
| Ontogeny of biochemical, morphological and functional parameters of synaptogenesis in primary cultur ... | Harrill, Joshua A; Chen, Hao; Streifel, Karin M; Yang, Dongren; Mundy, William R; Lein, Pamela ... | R01ES014901, T32ES007059 | Mol Brain (2015 Feb 15) |
25757474
|
2015 |
| Putative adverse outcome pathways relevant to neurotoxicity. | Bal-Price, Anna; Crofton, Kevin M; Sachana, Magdalini; Shafer, Timothy J; Behl, Mamta; Forsby, ... | R01ES014901 | Crit Rev Toxicol (2015 Jan) |
25605028
|
2015 |
| Reactive oxygen species are involved in BMP-induced dendritic growth in cultured rat sympathetic neu ... | Chandrasekaran, Vidya; Lea, Charlotte; Sosa, Jose Carlo; Higgins, Dennis; Lein, Pamela J | R01ES014901 | Mol Cell Neurosci (2015 Jul) |
26079955
|
2015 |
| Subacute nicotine co-exposure has no effect on 2,2',3,5',6- pentachlorobiphenyl disposition but alte ... | Stamou, Marianna; Uwimana, Eric; Flannery, Brenna M; Kania-Korwel, Izabela; Lehmler, Hans-Joach ... | P30ES005605, P42ES004699, R01ES014901 | Toxicology (2015 Dec 02) |
26463278
|
2015 |
| Using the Morris water maze to assess spatial learning and memory in weanling mice. | Barnhart, Christopher D; Yang, Dongren; Lein, Pamela J | P42ES004699, R01ES014901, T32ES007059 | PLoS One (2015) |
25886563
|
2015 |
| Cytochrome p450 mRNA expression in the rodent brain: species-, sex-, and region-dependent difference ... | Stamou, Marianna; Wu, Xianai; Kania-Korwel, Izabela; Lehmler, Hans-Joachim; Lein, Pamela J | P30ES005605, P42ES004699, R01ES014901 | Drug Metab Dispos (2014 Feb) |
24255117
|
2014 |
| Microsomal oxidation of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) results in species-dependent chi ... | Wu, Xianai; Kammerer, Austin; Lehmler, Hans-Joachim | P30ES005605, P30ES006694, P42ES013661, R01ES014901 | Environ Sci Technol (2014 Feb 18) |
24467194
|
2014 |
| Nanomolar bifenthrin alters synchronous Ca2+ oscillations and cortical neuron development independen ... | Cao, Zhengyu; Cui, Yanjun; Nguyen, Hai M; Jenkins, David Paul; Wulff, Heike; Pessah, Isaac N | P42ES004699, R01ES014901 | Mol Pharmacol (2014 Apr) |
24482397
|
2014 |
| PCB 136 atropselectively alters morphometric and functional parameters of neuronal connectivity in c ... | Yang, Dongren; Kania-Korwel, Izabela; Ghogha, Atefeh; Chen, Hao; Stamou, Marianna; Bose, Dipti ... | P30ES005605, P42ES004699, P42ES013661, R01ES014901, T32ES007059 | Toxicol Sci (2014 Apr) |
24385416
|
2014 |
| The environmental neurotoxicant PCB 95 promotes synaptogenesis via ryanodine receptor-dependent miR1 ... | Lesiak, Adam; Zhu, Mingyan; Chen, Hao; Appleyard, Suzanne M; Impey, Soren; Lein, Pamela J; Way ... | P42ES004699, R01ES014901, T32ES007059 | J Neurosci (2014 Jan 15) |
24431430
|
2014 |
| Metabolism of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) atropisomers in tissue slices from phenoba ... | Wu, Xianai; Kania-Korwel, Izabela; Chen, Hao; Stamou, Marianna; Dammanahalli, Karigowda J; Duff ... | P30ES005605, P30ES006694, P42ES004699, P42ES013661, R01ES014901, T32ES007059 | Xenobiotica (2013 Nov) |
23581876
|
2013 |
| Neuronal connectivity as a convergent target of gene ýý environment interactions that confer risk fo ... | Stamou, Marianna; Streifel, Karin M; Goines, Paula E; Lein, Pamela J | P42ES004699, R01ES014901 | Neurotoxicol Teratol (2013 Mar-Apr) |
23269408
|
2013 |
| Simultaneous determination of polybrominated diphenyl ethers and polychlorinated biphenyls by gas ch ... | Lin, Yan-ping; Pessah, Isaac N; Puschner, Birgit | P42ES004699, R01ES014901 | Talanta (2013 Sep 15) |
23708622
|
2013 |
| Structure-activity relationship of non-coplanar polychlorinated biphenyls toward skeletal muscle rya ... | Fritsch, Erika B; Pessah, Isaac N | P42ES004699, R01ES014901 | Aquat Toxicol (2013 Sep 15) |
23827775
|
2013 |
| Structure-activity relationship of selected meta- and para-hydroxylated non-dioxin like polychlorina ... | Niknam, Yassaman; Feng, Wei; Cherednichenko, Gennady; Dong, Yao; Joshi, Sudhir N; Vyas, Sandhy ... | P30ES005605, P42ES004699, P42ES013661, R01ES014901 | Toxicol Sci (2013 Dec) |
24014653
|
2013 |
| Triclosan impairs swimming behavior and alters expression of excitation-contraction coupling protein ... | Fritsch, Erika B; Connon, Richard E; Werner, Inge; Davies, Rebecca E; Beggel, Sebastian; Feng, ... | P42ES004699, R01ES014901 | Environ Sci Technol (2013 Feb 19) |
23305567
|
2013 |
| 2,2',3,5',6-Pentachlorobiphenyl (PCB 95) and its hydroxylated metabolites are enantiomerically enric ... | Kania-Korwel, Izabela; Barnhart, Christopher D; Stamou, Marianna; Truong, Kim M; El-Komy, Moham ... | P30ES005605, P42ES004699, P42ES013661, R01ES014901, T32ES007059 | Environ Sci Technol (2012 Oct 16) |
22974126
|
2012 |
| Gene dose influences cellular and calcium channel dysregulation in heterozygous and homozygous T4826 ... | Barrientos, Genaro C; Feng, Wei; Truong, Kim; Matthaei, Klaus I; Yang, Tianzhong; Allen, Paul ... | R01ES014901 | J Biol Chem (2012 Jan 20) |
22139840
|
2012 |
| Inducing dendritic growth in cultured sympathetic neurons. | Ghogha, Atefeh; Bruun, Donald A; Lein, Pamela J | R01ES014901 | J Vis Exp (2012) |
22473299
|
2012 |
| Levels of select PCB and PBDE congeners in human postmortem brain reveal possible environmental invo ... | Mitchell, Michelle M; Woods, Rima; Chi, Lai-Har; Schmidt, Rebecca J; Pessah, Isaac N; Kostyniak ... | R01ES014901 | Environ Mol Mutagen (2012 Oct) |
22930557
|
2012 |
| Maternal transfer of BDE-47 to offspring and neurobehavioral development in C57BL/6J mice. | Koenig, Claire M; Lango, Jozsef; Pessah, Isaac N; Berman, Robert F | P42ES004699, R01ES014901, T32ES007059 | Neurotoxicol Teratol (2012 Nov-Dec) |
23022914
|
2012 |
| Mice expressing T4826I-RYR1 are viable but exhibit sex- and genotype-dependent susceptibility to mal ... | Yuen, Benjamin; Boncompagni, Simona; Feng, Wei; Yang, Tianzhong; Lopez, Jose R; Matthaei, Klau ... | R01ES014901 | FASEB J (2012 Mar) |
22131268
|
2012 |
| PCB-95 modulates the calcium-dependent signaling pathway responsible for activity-dependent dendriti ... | Wayman, Gary A; Bose, Diptiman D; Yang, Dongren; Lesiak, Adam; Bruun, Donald; Impey, Soren; Le ... | P42ES004699, R01ES014901, T32ES007060 | Environ Health Perspect (2012 Jul) |
22534176
|
2012 |
| PCB-95 promotes dendritic growth via ryanodine receptor-dependent mechanisms. | Wayman, Gary A; Yang, Dongren; Bose, Diptiman D; Lesiak, Adam; Ledoux, Veronica; Bruun, Donald ... | P42ES004699, R01ES014901, T32ES007060 | Environ Health Perspect (2012 Jul) |
22534141
|
2012 |
| Translating neurobehavioural endpoints of developmental neurotoxicity tests into in vitro assays and ... | van Thriel, Christoph; Westerink, Remco H S; Beste, Christian; Bale, Ambuja S; Lein, Pamela J; ... | R01ES014901 | Neurotoxicology (2012 Aug) |
22008243
|
2012 |
| 2,2',3,3',6,6'-Hexachlorobiphenyl (PCB 136) is enantioselectively oxidized to hydroxylated metabolit ... | Wu, Xianai; Pramanik, Ananya; Duffel, Michael W; Hrycay, Eugene G; Bandiera, Stelvio M; Lehmler ... | P30ES005605, P30ES006694, P42ES013661, R01ES014901 | Chem Res Toxicol (2011 Dec 19) |
22026639
|
2011 |
| Acute hippocampal slice preparation and hippocampal slice cultures. | Lein, Pamela J; Barnhart, Christopher D; Pessah, Isaac N | R01ES014901, T32ES007059 | Methods Mol Biol (2011) |
21815062
|
2011 |
| Bioaccumulation and behavioral effects of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) in perinatally ... | Ta, Tram Anh; Koenig, Claire M; Golub, Mari S; Pessah, Isaac N; Qi, Lihong; Aronov, Pavel A; B ... | P42ES004699, R01ES014901, T32ES007059 | Neurotoxicol Teratol (2011 May-Jun) |
21334437
|
2011 |
| Channelopathies: summary of the hot topic keynotes session. | Magby, Jason P; Neal, April P; Atchison, William D; Pessah, Isaac P; Shafer, Timothy J | P30ES005022, P42ES004699, R01ES014901 | Neurotoxicology (2011 Oct) |
21756936
|
2011 |
| Epoxyeicosatrienoic acids enhance axonal growth in primary sensory and cortical neuronal cell cultur ... | Abdu, Emun; Bruun, Donald A; Yang, Dongren; Yang, Jun; Inceoglu, Bora; Hammock, Bruce D; Alkay ... | P42ES004699, R01ES014901 | J Neurochem (2011 May) |
21155804
|
2011 |
| Functional and biochemical properties of ryanodine receptor type 1 channels from heterozygous R163C ... | Feng, Wei; Barrientos, Genaro C; Cherednichenko, Gennady; Yang, Tianzhong; Padilla, Isela T; Tr ... | P42ES004699, R01ES014901 | Mol Pharmacol (2011 Mar) |
21156754
|
2011 |
| Para- and ortho-substitutions are key determinants of polybrominated diphenyl ether activity toward ... | Kim, Kyung Ho; Bose, Diptiman D; Ghogha, Atefeh; Riehl, Joyce; Zhang, Rui; Barnhart, Christoph ... | P42ES004699, R01ES014901, T32ES007059 | Environ Health Perspect (2011 Apr) |
21106467
|
2011 |
| Perinatal exposure to environmental polychlorinated biphenyls sensitizes hippocampus to excitotoxici ... | Kim, Kyung Ho; Pessah, Isaac N | P42ES004699, R01ES014901 | Neurotoxicology (2011 Dec) |
21571002
|
2011 |
| Transcriptional responses of cultured rat sympathetic neurons during BMP-7-induced dendritic growth. | Garred, Michelle M; Wang, Michael M; Guo, Xin; Harrington, Christina A; Lein, Pamela J | R01ES014901 | PLoS One (2011) |
21765909
|
2011 |
| Method for Shipping Live Cultures of Dissociated Rat Hippocampal Neurons. | Yang, Dongren; Bruun, Donald; Andres, Douglas A; Lein, Pamela J | R01ES014901 | Curr Neurobiol (2010 Oct) |
24052689
|
2010 |
| Minding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicity. | Pessah, Isaac N; Cherednichenko, Gennady; Lein, Pamela J | P42ES004699, R01ES014901 | Pharmacol Ther (2010 Feb) |
19931307
|
2010 |
| Polychlorinated biphenyls increase apoptosis in the developing rat brain. | Yang, Dongren; Lein, Pamela J | R01ES014901 | Curr Neurobiol (2010 Mar) |
24052688
|
2010 |
| Animal models of autism spectrum disorders: information for neurotoxicologists. | Halladay, Alycia K; Amaral, David; Aschner, Michael; Bolivar, Valerie J; Bowman, Aaron; DiCicco ... | P42ES004699, R01ES014901 | Neurotoxicology (2009 Sep) |
19596370
|
2009 |
| Coordinated movement of cytoplasmic and transmembrane domains of RyR1 upon gating. | Samsó, Montserrat; Feng, Wei; Pessah, Isaac N; Allen, P D | R01ES014901 | PLoS Biol (2009 Apr 14) |
19402748
|
2009 |
| Developmental exposure to polychlorinated biphenyls interferes with experience-dependent dendritic p ... | Yang, Dongren; Kim, Kyung Ho; Phimister, Andrew; Bachstetter, Adam D; Ward, Thomas R; Stackman, ... | R01ES014901 | Environ Health Perspect (2009 Mar) |
19337518
|
2009 |
| Enantiomeric specificity of (-)-2,2',3,3',6,6'-hexachlorobiphenyl toward ryanodine receptor types 1 ... | Pessah, Isaac N; Lehmler, Hans-Joachim; Robertson, Larry W; Perez, Claudio F; Cabrales, Elaine; ... | P42ES004699, P42ES013661, R01ES014901 | Chem Res Toxicol (2009 Jan) |
18954145
|
2009 |
| Excitatory and inhibitory synaptic transmission is differentially influenced by two ortho-substitute ... | Kim, Kyung Ho; Inan, Salim Yalcin; Berman, Robert F; Pessah, Isaac N | P42ES004699, R01ES014901 | Toxicol Appl Pharmacol (2009 Jun 01) |
19289137
|
2009 |
| Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key en ... | Morisseau, Christophe; Merzlikin, Oleg; Lin, Amy; He, Guochun; Feng, Wei; Padilla, Isela; Deni ... | P42ES004699, R01ES014901 | Environ Health Perspect (2009 Dec) |
20049205
|
2009 |
| Developmental exposure to polychlorinated biphenyls influences stroke outcome in adult rats. | Dziennis, Suzan; Yang, Dongren; Cheng, Jian; Anderson, Kim A; Alkayed, Nabil J; Hurn, Patricia ... | R01ES014901 | Environ Health Perspect (2008 Apr) |
18414629
|
2008 |
| Immunologic and neurodevelopmental susceptibilities of autism. | Pessah, Isaac N; Seegal, Richard F; Lein, Pamela J; LaSalle, Janine; Yee, Benjamin K; Van De Wa ... | R01ES014901 | Neurotoxicology (2008 May) |
18394707
|
2008 |