Project Title: | DEFINING THE MOLECULAR BASIS OF ONCOGENE-INDUCED REPLICATION STRESS |
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PI: | Huang, Tony Tung |
Institution: | New York University School Of Medicine |
Grant Number: | R01ES031658 |
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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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Dormant origin firing promotes head-on transcription-replication conflicts at transcription terminat ... | Goehring, Liana; Keegan, Sarah; Lahiri, Sudipta; Xia, Wenxin; Kong, Michael; Jimenez-Sainz, Ju ... | R01ES031658 | Nat Commun (2024 Jun 03) | 38830843 | 2024 |
Transcription-Replication Conflicts as a Source of Genome Instability. | Goehring, Liana; Huang, Tony T; Smith, Duncan J | R01ES031658 | Annu Rev Genet (2023 Nov 27) | 37552891 | 2023 |
USP1-trapping lesions as a source of DNA replication stress and genomic instability. | Coleman, Kate E; Yin, Yandong; Lui, Sarah Kit Leng; Keegan, Sarah; Fenyo, David; Smith, Duncan ... | R01ES031658 | Nat Commun (2022 Apr 01) | 35365626 | 2022 |
A basal-level activity of ATR links replication fork surveillance and stress response. | Yin, Yandong; Lee, Wei Ting Chelsea; Gupta, Dipika; Xue, Huijun; Tonzi, Peter; Borowiec, James ... | R01ES031658 | Mol Cell (2021 10 21) | 34473946 | 2021 |
Fused in sarcoma regulates DNA replication timing and kinetics. | Jia, Weiyan; Kim, Sang Hwa; Scalf, Mark A; Tonzi, Peter; Millikin, Robert J; Guns, William M; ... | R01ES031658 | J Biol Chem (2021 Sep) | 34375640 | 2021 |
Monitoring genome-wide replication fork directionality by Okazaki fragment sequencing in mammalian c ... | Kit Leng Lui, Sarah; Keegan, Sarah; Tonzi, Peter; Kahli, Malik; Chen, Yu-Hung; Chalhoub, Noor; ... | R01ES031658 | Nat Protoc (2021 02) | 33442052 | 2021 |
Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinder ... | Lee, Wei Ting C; Yin, Yandong; Morten, Michael J; Tonzi, Peter; Gwo, Pam Pam; Odermatt, Diana ... | R01ES031658 | Nat Commun (2021 05 05) | 33953191 | 2021 |
WEE1i-ATRi combination therapy: a promising low-dose treatment for CCNE1-amplified gynecologic cance ... | Goehring, Liana; Huang, Tony T | R01ES031658 | Cell Rep Med (2021 Sep 21) | 34622238 | 2021 |