Project Title: | RAD51 PARALOG FUNCTION IN CANCER PREDISPOSITION AND GENOME INTEGRITY |
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PI: | Bernstein, Kara A |
Institution: | University Of Pennsylvania |
Grant Number: | R01ES031796 |
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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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Variants in the first methionine of RAD51C are homologous recombination proficient due to an alterna ... | Rein, Hayley L; Bernstein, Kara A | R01ES030335, R01ES031796 | DNA Repair (Amst) (2024 Mar) | 38330859 | 2024 |
Finding significance: New perspectives in variant classification of the RAD51 regulators, BRCA2 and ... | Rein, Hayley L; Bernstein, Kara A | P30ES013508, R01ES031796 | DNA Repair (Amst) (2023 Oct) | 37651978 | 2023 |
Structural insights into BCDX2 complex function in homologous recombination. | Rawal, Yashpal; Jia, Lijia; Meir, Aviv; Zhou, Shuo; Kaur, Hardeep; Ruben, Eliza A; Kwon, Youn ... | P30ES013508, R01ES007061, R01ES030335, R01ES031796 | Nature (2023 Jul) | 37344589 | 2023 |
Unlicensed origin DNA melting by MCV and SV40 polyomavirus LT proteins is independent of ATP-depende ... | Wan, Li; Toland, Sabrina; Robinson-McCarthy, Lindsey R; Lee, Nara; Schaich, Matthew A; Hengel, ... | R01ES030335, R01ES031796, R35ES031638 | Proc Natl Acad Sci U S A (2023 Jul 25) | 37459531 | 2023 |
Homologous recombination-deficient mutation cluster in tumor suppressor RAD51C identified by compreh ... | Prakash, Rohit; Rawal, Yashpal; Sullivan, Meghan R; Grundy, McKenzie K; Bret, Hélène; Mihalevic ... | R01ES007061, R01ES031796 | Proc Natl Acad Sci U S A (2022 Sep 20) | 36099300 | 2022 |
Targeting Therapeutic Resistance and Multinucleate Giant Cells in CCNE1-Amplified HR-Proficient Ovar ... | Bai, Shoumei; Taylor, Sarah E; Jamalruddin, Mohd Azrin; McGonigal, Stacy; Grimley, Edward; Yang ... | R01ES031796 | Mol Cancer Ther (2022 Sep 06) | 35732503 | 2022 |
Aldehyde dehydrogenase inhibitors promote DNA damage in ovarian cancer and synergize with ATM/ATR in ... | Grimley, Edward; Cole, Alexander J; Luong, Thong T; McGonigal, Stacy C; Sinno, Sarah; Yang, Do ... | R01ES030335, R01ES031796 | Theranostics (2021) | 33664846 | 2021 |
Long-term survival of an ovarian cancer patient harboring a RAD51C missense mutation. | Sullivan, Meghan R; Prakash, Rohit; Rawal, Yashpal; Wang, Weibin; Sung, Patrick; Radke, Marc R ... | R01ES007061, R01ES030335, R01ES031796 | Cold Spring Harb Mol Case Stud (2021 Apr) | 33832919 | 2021 |
RAD51 paralog function in replicative DNA damage and tolerance. | Rein, Hayley L; Bernstein, Kara A; Baldock, Robert A | R01ES030335, R01ES031796 | Curr Opin Genet Dev (2021 Dec) | 34311385 | 2021 |