Superfund Research Program
Zebrafish as a Detector and Discriminator of Organophosphate Exposure
Project Leaders: Elwood A. Linney (Duke University Medical Center), Richard T. Di Giulio
Grant Number: P42ES010356
Funding Period: 2000-2011
Project-Specific Links
Publications
2011
- Levin ED, Petro A, Donerly S, Linney EA, Sledge D, Roach S. 2011. Persistent behavioral impairment caused by embryonic methylphenidate exposure in zebrafish. Neurotoxicol Teratol 33:668-673. doi:10.1016/j.ntt.2011.06.004 PMID:21741476 PMCID:PMC3225500
- Sledge D, Yen J, Morton T, Dishaw L, Petro A, Donerly S, Linney EA, Levin ED. 2011. Critical duration of exposure for developmental chlorpyrifos-induced neurobehavioral toxicity. Neurotoxicol Teratol 33:742-751. doi:10.1016/j.ntt.2011.06.005 PMID:21745564 PMCID:PMC3225562
- Yen J, Donerly S, Levin ED, Linney EA. 2011. Differential acetylcholinesterase inhibition of chlorpyrifos, diazinon and parathion in larval zebrafish. Neurotoxicol Teratol 33:735-741. doi:10.1016/j.ntt.2011.10.004 PMID:22036888 PMCID:PMC3225599
2010
- Alexeyenko A, Wassenberg DM, Lobenhofer EK, Yen J, Linney EA, Sonnhammer E, Meyer JN. 2010. Dynamic zebrafish interactome reveals transcriptional mechanisms of dioxin toxicity. PLoS One 5(5):e10465. doi:10.1371/journal.pone.0010465 PMID:20463971 PMCID:PMC2864754
2007
- Lassiter CS, Linney EA. 2007. Embryonic expression and steroid regulation of brain aromatase cyp19a1b in zebrafish (Danio rerio). Zebrafish 4(1):49-57. doi:10.1089/zeb.2006.9995 PMID:18041942
2006
- Cook J, Denslow ND, Iguchi T, Linney EA, Miracle A, Shaw JR, Viant MR, Zacharewski TR. 2006. "Omics" approaches in the context of environment toxicology. (In: Emerging Molecular and Computational Approaches for Cross-Species Extrapolations). Chapter 1in: Society of Environmental Toxicology and Chemistry (SETAC) Annual Meeting 2006. Washington, DC. pp.1-29.
2004
- Levin ED, Swain HA, Donerly S, Linney EA. 2004. Developmental chlorpyrifos effects on hatchling zebrafish swimming behavior. Neurotoxicol Teratol 26(6):719-723. PMID:15451035
- Linney EA, Udvadia AJ. 2004. Construction and detection of fluorescent germline transgenic zebrafish. Chapter Vol. 254 in: Methods in Molecular Biology, 2004. Humana Press, Inc, Louisville, KY. pp.271-288.
- Linney EA, Upchurch L, Donerly S. 2004. Zebrafish as a neurotoxicological model. Neurotoxicol Teratol 26(6):709-718. PMID:15451034
2003
- Levin ED, Chrysanthis E, Yacsin K, Linney EA. 2003. Chlorpyrifos exposure of developing zebrafish: effects on survival and long-term effects on response latency and spatial discrimination. Neurotoxicol Teratol 25(1):51-57. PMID:12633736
- Linney EA, Udvadia AJ. 2003. Construction and detection of fluorescent germ-line transgenic zebrafish. In: Methods Mol Med. (). Humana Press,
- Udvadia AJ, Linney EA. 2003. Windows into development: historic, current, and future perspectives on transgenic zebrafish. Dev Biol 256(1):1-17. PMID:12654288
2002
- Lassiter CS, Linney EA, Kelley B. 2002. Genomic structure and embryonic expression of estrogen receptor beta a (ERBa) in zebrafish (Danio rerio). Gene 292(1-2):141-151. doi:10.1016/S0378-1119(02)01050-8 PMID:12459262