TR-599: Technical Report Pathology Tables and Curves

Pathology Tables, Survival and Growth Curves from NTP
Short-Term, Long Term, and Genetic Toxicology Studies

https://doi.org/10.22427/NTP-DATA-TR-599

Gestational/Lactational and Litter tables were re-analyzed and updated tables posted on 5-November-2019

On 1/20/2020 duplicate E03 and E04 tables were removed from the Rat chronic study. Water consumption tables and graphs of biological sample analysis were also added for each study.

E08 tables were added on 17-April-2020

Genetox studies were added on 10-October-2020

The PA06 table and individual animal data was updated to reflect correct animal assignments on 02-Jul-2021

TR-599: Sodium Tungstate Dihydrate

Short-Term

Long Term

Chronic with Perinatal Study Tables - Rats

Analysis of PND 1 Litter Data (23KB)
Analysis of PND 4 Live Litter Size and Survival (24KB)
E01 - Animal Removal Summary By Treatment Group (13KB)
E02 - Animals Removed from Experiment (148KB)
E03 - Growth Curves (Litter based) (63KB)
E04 - Mean Body Weights and Survival (Litter based) (19KB)
E05 - Clinical Observations Summary (22KB)
E07 - Mean Water Consumption by Treatment Group (26KB)
E08 - Water and Compound Consumption Table (38KB)
E12 - Animal History (1MB)
I05 - Clinical Observations Summary (46KB)
Litter Data Analysis of Gestational Body Weight (20KB)
Litter Data Analysis of Gestational Water Consumption (18KB)
Litter Data Analysis of Gestational/Lactational Chemical Consumption (20KB)
Litter Data Analysis of Lactational Body Weight (21KB)
Litter Data Analysis of Lactational Water Consumption (19KB)
Litter Data Analysis of Pup Body Weights (22KB)
Litter Data Analysis of Pup Body Weights (cont'd) (14KB)
P02 - Incidence Rates of Neoplasms by Anatomic Site (54KB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (67KB)
P04 - Neoplasms by Individual Animal (663KB)
P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (51KB)
P08 - Litter Statistical Analysis of Primary Tumors (178KB)
P09 - Non-Neoplastic Lesions by Individual Animal (913KB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (535KB)
P11 - Statistical Analysis of Survival Data (21KB)
P14 - Individual Animal Pathology Data (1MB)
P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (594KB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (70KB)
P40 - Survival Curves (487KB)
PA06 - Organ Weights Summary (235KB)
PA48 - Summary of Tissue Concentration (177KB)
PA48C - Tissue Concentration Curve (4MB)
R02 - Reproductive Performance Summary (39KB)

Chronic with Perinatal Individual Animal Data - Rats

Female Individual Animal Body Weight Data (393KB)
Female Individual Animal Clinical Observations (206KB)
Female Individual Animal Neoplastic Pathology Data (110KB)
Female Individual Animal Non Neoplastic Pathology Data (565KB)
Female Individual Animal Survival Data (34KB)
Female Individual Animal Terminal Body Weight Data (57KB)
Female Pup Individual Animal Body Weight Data (41KB)
Male Individual Animal Body Weight Data (397KB)
Male Individual Animal Clinical Observations (183KB)
Male Individual Animal Neoplastic Pathology Data (107KB)
Male Individual Animal Non Neoplastic Pathology Data (797KB)
Male Individual Animal Survival Data (33KB)
Male Individual Animal Terminal Body Weight Data (57KB)
Male Pup Individual Animal Body Weight Data (235KB)
Individual Animal Clinical Observations Data (10KB)
Individual Animal DamID and PupID Data (30KB)
Individual Animal Organ Weight Data (28KB)
Individual Animal Reproductive Performance Data (11KB)
Individual Animal Tissue Concentration Data (19KB)
Individual Animal Urinalysis Data (21KB)
Individual Pup Census and Litter Weight by Sex Data (26KB)

Chronic Study Tables - Mice

E01 - Animal Removal Summary By Treatment Group (13KB)
E02 - Animals Removed from Experiment (110KB)
E03 - Growth Curves (470KB)
E04 - Mean Body Weights and Survival Table (24KB)
E05 - Clinical Observations Summary (20KB)
E07 - Mean Water Consumption by Treatment Group (25KB)
E08 - Water and Compound Consumption Table (36KB)
E12 - Animal History (1MB)
P02 - Incidence Rates of Neoplasms by Anatomic Site (57KB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (64KB)
P04 - Neoplasms by Individual Animal (734KB)
P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (51KB)
P08 - Statistical Analysis of Primary Tumors (224KB)
P09 - Non-Neoplastic Lesions by Individual Animal (885KB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (564KB)
P11 - Statistical Analysis of Survival Data (24KB)
P14 - Individual Animal Pathology Data (1MB)
P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (608KB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (66KB)
P40 - Survival Curves (453KB)
PA06_Organ_Weight_Summary (236KB)
PA48 - Summary_of_Tissue_Concentration (167KB)
PA48C - Tissue Concentration Curve (3MB)

Chronic Individual Animal Data - Mice

Female Individual Animal Body Weight Data (320KB)
Female Individual Animal Clinical Observations (30KB)
Female Individual Animal Neoplastic Pathology Data (148KB)
Female Individual Animal Non Neoplastic Pathology Data (520KB)
Female Individual Animal Survival Data (34KB)
Female Individual Animal Terminal Body Weight Data (57KB)
Male Individual Animal Body Weight Data (377KB)
Male Individual Animal Clinical Observations (74KB)
Male Individual Animal Neoplastic Pathology Data (148KB)
Male Individual Animal Non Neoplastic Pathology Data (627KB)
Male Individual Animal Survival Data (34KB)
Male Individual Animal Terminal Body Weight Data (57KB)
Individual Animal Organ Weight Data (25KB)
Individual Animal Tissue Concentration Data (19KB)
Individual Animal Urinalysis Data (20KB)

COVID-19 is an emerging, rapidly evolving situation.

TR-599: Technical Report Pathology Tables and Curves

Pathology Tables, Survival and Growth Curves from NTP
Short-Term, Long Term, and Genetic Toxicology Studies

TR-599: Sodium Tungstate Dihydrate

Short-Term

3-Month with Perinatal Study Tables - Rats

3-Month with Perinatal Individual Animal Data - Rats

3-Month Study Tables - Mice

3-Month Individual Animal Data - Mice

Long Term

Chronic with Perinatal Study Tables - Rats

Chronic with Perinatal Individual Animal Data - Rats

Chronic Study Tables - Mice

Chronic Individual Animal Data - Mice

Genetic Toxicology

Genetic Toxicity Evaluation of Sodium Tungstate Dihydrate (10213-10-2) in Micronucleus Study G03038B in B6C3F1 Mice

Genetic Toxicity Evaluation of Sodium Tungstate Dihydrate (10213-10-2) in Micronucleus Study G03038C in Harlan Sprague-Dawley Rats

Genetic Toxicity Evaluation of Sodium Tungstate Dihydrate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G03038D

Genetic Toxicity Evaluation of Sodium Tungstate Dihydrate (10213-10-2) in DNA Damage Study G03038E in B6C3F1 Mice

Genetic Toxicity Evaluation of Sodium Tungstate Dihydrate (10213-10-2) in DNA Damage Study G03038F in Harlan Sprague Dawley Rats

TR-599: Technical Report Pathology Tables and Curves

Pathology Tables, Survival and Growth Curves from NTP Short-Term, Long Term, and Genetic Toxicology Studies

TR-599: Sodium Tungstate Dihydrate

Short-Term

3-Month with Perinatal Study Tables - Rats

3-Month with Perinatal Individual Animal Data - Rats

3-Month Study Tables - Mice

3-Month Individual Animal Data - Mice

Long Term

Chronic with Perinatal Study Tables - Rats

Chronic with Perinatal Individual Animal Data - Rats

Chronic Study Tables - Mice

Chronic Individual Animal Data - Mice

Genetic Toxicology

Genetic Toxicity Evaluation of Sodium Tungstate Dihydrate (10213-10-2) in Micronucleus Study G03038B in B6C3F1 Mice

Genetic Toxicity Evaluation of Sodium Tungstate Dihydrate (10213-10-2) in Micronucleus Study G03038C in Harlan Sprague-Dawley Rats

Genetic Toxicity Evaluation of Sodium Tungstate Dihydrate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G03038D

Genetic Toxicity Evaluation of Sodium Tungstate Dihydrate (10213-10-2) in DNA Damage Study G03038E in B6C3F1 Mice

Genetic Toxicity Evaluation of Sodium Tungstate Dihydrate (10213-10-2) in DNA Damage Study G03038F in Harlan Sprague Dawley Rats

Pathology Tables, Survival and Growth Curves from NTP
Short-Term, Long Term, and Genetic Toxicology Studies