Reproductive and Developmental Toxicity Assessment of Butyl Paraben in Hsd: Sprague Dawley SD rats following Feed Exposure
https://doi.org/10.22427/NTP-DATA-NTP-DATA-RACB-BP
Note: The study data are being disseminated prior to external peer review under applicable information quality guidelines and do not represent and should not be construed to represent any final NTP determination or policy.
Reproductive Assessment Through Continuous Breeding
Dose Range Finding Study Tables
- I01 - Animal Removal Summary (46KB)
- I03 - Growth Curve (1MB)
- I03C - Growth Curve (1MB)
- I04 - Mean Body Weight Summary (187KB)
- I04G - Mean Body Weight Gain (61KB)
- I05 - Clinical Observations Summary (94KB)
- I05P - Pup Clinical Observations Summary (89KB)
- I06 - Mean Feed Consumption (199KB)
- I08 - Mean Test Compound Consumption (145KB)
- R02 - Reproductive Performance Summary (49KB)
- R03 - Summary of Litter Data (47KB)
- R19 - Pup Mean Body Weight Summary (114KB)
- R19C - Pup Growth Curves (802KB)
- R19G - Pup Mean Body Weight Gain (90KB)
- R20 - Pup Necropsy Summary (172KB)
Dose Range Finding Individual Animal Data
- Individual Animal Body Weight Data (41KB)
- Individual Animal Clinical Observations Data (135KB)
- Individual Animal Consumption Data (63KB)
- Individual Animal Gross Pathology Data (5KB)
- Individual Animal Litter Data (14KB)
- Individual Animal Pup Body Weight Data (33KB)
- Individual Animal Pup Clinical Observations Data (67KB)
- Individual Animal Pup Necropsy Data (8KB)
- Individual Animal Removal Reasons Data (7KB)
- Individual Animal Reproductive Performance Data (7KB)
Main Study RACB Tables
- I01 - Animal Removal Summary (175KB)
- I03 - Growth Curve (5MB)
- I03C - Growth Curve (5MB)
- I04 - Mean Body Weight Summary (1MB)
- I04G - Mean Body Weight Gain (470KB)
- I05 - Clinical Observations Summary (2MB)
- I05P - Pup Clinical Observations Summary (853KB)
- I06 - Mean Feed Consumption (1MB)
- I08 - Mean Test Compound Intake (704KB)
- I23 - Average Dose by Phase (90KB)
- PA02R - Neoplastic Lesion Summary with Percent and Litter Incidence (721KB)
- PA03R - Non-Neoplastic Lesion Summary with Percent and Litter Incidence (988KB)
- PA05R - Incidence Rates of Neoplastic Lesions with Litter Incidence Systemic Lesions Abridged (722KB)
- PA06R - Organ Weights Summary (272KB)
- PA08R - Statistical Analysis of Neoplastic Lesions with Litter Incidence (611KB)
- PA10R - Statistical Analysis of Non-Neoplastic Lesions with Litter Incidence (995KB)
- PA14 - Individual Animal Pathology Data (10MB)
- PA18R - Non-Neoplastic Lesion Summary with Mean Severity Grade and Litter Incidence (988KB)
- PA46R Summary of Gross Pathology with Litter Summary (1MB)
- R02 Reproductive Performance Summary (142KB)
- R03 - Summary of Litter Data (212KB)
- R04 - Anogenital Distance Summary (126KB)
- R06 - Andrology Summary (111KB)
- R14 - Developmental Markers Summary (148KB)
- R16 - Pubertal Markers Summary (161KB)
- R19 - Pup Mean Body Weight Summary (548KB)
- R19C - Pup Growth Curve (5MB)
- R19G - Pup Mean Body Weight Gain (380KB)
- R20 - Pup Necropsy Summary (785KB)
- R21 - Cross Generational Summary of Reproductive Performance (64KB)
- R22 - Cross Generational Summary of Litters (73KB)
- Vaginal Cytology Summary (288KB)
- Vaginal Cytology Plots (596KB)
- Vaginal Cytology Transition Matrix (449KB)
Main Study RACB Individual Animal Data
- Individual Animal Andrology Data (32KB)
- Individual Animal Body Weight Data (1MB)
- Individual Animal Clinical Observations Data (5MB)
- Individual Animal Consumption Data (1MB)
- Individual Animal Developmental Markers Data (506KB)
- Individual Animal Gross Pathology Data (495KB)
- Individual Animal Histopathology Data (272KB)
- Individual Animal Litter Crossover Data (13KB)
- Individual Animal Litter Data (320KB)
- Individual Animal Organ Weight Data (89KB)
- Individual Animal Pup Body Weight Data (782KB)
- Individual Animal Pup Clinical Observations Data (3MB)
- Individual Animal Pup Necropsy Data (88KB)
- Individual Animal Removal Reasons Data (66KB)
- Individual Animal Reproductive Performance Crossover Data (6KB)
- Individual Animal Reproductive Performance Data (32KB)
- Individual Animal Vaginal Cytology Data (246KB)