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Your Environment. Your Health.

Who We Fund: Publication Detail

Project Title: ACTIVATED MACROPHAGES AND OZONE TOXICITY
PI: Laskin, Debra L
Institution: Rutgers, The State Univ Of N.J.
Grant Number: R01ES004738

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 171 publications
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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Assessment of mustard vesicant lung injury and anti-TNF-α efficacy in rodents using live-animal imag ...   Murray, Alexa; Gow, Andrew J; Venosa, Alessandro; Andres, Jaclynn; Malaviya, Rama; Adler, Dere ... P30ES005022, R01ES004738, R21ES029254, T32ES007148 Ann N Y Acad Sci (2020 11) 33165947 Exiting the NIEHS site 2020 
Disease-modifying treatment of chemical threat agent-induced acute lung injury.   Radbel, Jared; Laskin, Debra L; Laskin, Jeffrey D; Kipen, Howard M P30ES005022, R01ES004738 Ann N Y Acad Sci (2020 11) 32726497 Exiting the NIEHS site 2020 
DNA damage signaling in the cellular responses to mustard vesicants.   Jan, Yi-Hua; Heck, Diane E; Laskin, Debra L; Laskin, Jeffrey D P30ES005022, R01ES004738 Toxicol Lett (2020 Jun 15) 32173488 Exiting the NIEHS site 2020 
Lung injury, oxidative stress and fibrosis in mice following exposure to nitrogen mustard.   Sunil, Vasanthi R; Vayas, Kinal N; Abramova, Elena V; Rancourt, Raymond; Cervelli, Jessica A; M ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2020 01 15) 31678244 Exiting the NIEHS site 2020 
Nutraceuticals as potential therapeutics for vesicant-induced pulmonary fibrosis.   Businaro, Rita; Maggi, Elisa; Armeli, Federica; Murray, Alexa; Laskin, Debra L P30ES005022, R01ES004738, T32ES007148 Ann N Y Acad Sci (2020 11) 32725637 Exiting the NIEHS site 2020 
Role of extracellular vesicles in cell-cell communication and inflammation following exposure to pul ...   Andres, Jaclynn; Smith, Ley Cody; Murray, Alexa; Jin, Yang; Businaro, Rita; Laskin, Jeffrey D; ... P30ES005022, R01ES004738, T32ES007148 Cytokine Growth Factor Rev (2020 02) 31901309 Exiting the NIEHS site 2020 
The amplex red/horseradish peroxidase assay requires superoxide dismutase to measure hydrogen peroxi ...   Mishin, Vladimir; Heck, Diane E; Laskin, Debra L; Laskin, Jeffrey D P30ES005022, R01ES004738 Free Radic Res (2020 Sep) 32912004 Exiting the NIEHS site 2020 
Transcriptional profiling of lung macrophages during pulmonary injury induced by nitrogen mustard.   Smith, L Cody; Venosa, Alessandro; Gow, Andrew J; Laskin, Jeffrey D; Laskin, Debra L P30ES005022, R01ES004738, R21ES029254, T32ES007148 Ann N Y Acad Sci (2020 11) 32767459 Exiting the NIEHS site 2020 
Regulation of Macrophage Foam Cell Formation During Nitrogen Mustard (NM)-Induced Pulmonary Fibrosis ...   Venosa, Alessandro; Smith, Ley Cody; Murray, Alexa; Banota, Tanvi; Gow, Andrew J; Laskin, Jeff ... P30ES005022, R01ES004738, T32ES007148 Toxicol Sci (2019 12 01) 31428777 Exiting the NIEHS site 2019 
Role of Macrophages in Acute Lung Injury and Chronic Fibrosis Induced by Pulmonary Toxicants.   Laskin, Debra L; Malaviya, Rama; Laskin, Jeffrey D P30ES005022, R01ES004738 Toxicol Sci (2019 04 01) 30590802 Exiting the NIEHS site 2019 
Sulfur Mustard Analog Mechlorethamine (Bis(2-chloroethyl)methylamine) Modulates Cell Cycle Progressi ...   Jan, Yi-Hua; Heck, Diane E; Laskin, Debra L; Laskin, Jeffrey D P30ES005022, R01ES004738 Chem Res Toxicol (2019 06 17) 30964658 Exiting the NIEHS site 2019 
Functional Evidence of Pulmonary Extracellular Vesicles in Infectious and Noninfectious Lung Inflamm ...   Lee, Heedoo; Zhang, Duo; Laskin, Debra L; Jin, Yang P30ES005022, R01ES004738 J Immunol (2018 09 01) 29997122 Exiting the NIEHS site 2018 
Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase.   Szilagyi, John T; Fussell, Karma C; Wang, Yun; Jan, Yi-Hua; Mishin, Vladimir; Richardson, Jaso ... P30ES005022, R01ES004738, T32ES007148 Toxicol Appl Pharmacol (2018 11 15) 30222979 Exiting the NIEHS site 2018 
Anti-TNFα therapy in inflammatory lung diseases.   Malaviya, Rama; Laskin, Jeffrey D; Laskin, Debra L P30ES005022, R01ES004738 Pharmacol Ther (2017 Dec) 28642115 Exiting the NIEHS site 2017 
Diacetyl/l-Xylulose Reductase Mediates Chemical Redox Cycling in Lung Epithelial Cells.   Yang, Shaojun; Jan, Yi-Hua; Mishin, Vladimir; Heck, Diane E; Laskin, Debra L; Laskin, Jeffrey ... P30ES005022, R01ES004738 Chem Res Toxicol (2017 07 17) 28595002 Exiting the NIEHS site 2017 
Editor's Highlight: CCR2 Regulates Inflammatory Cell Accumulation in the Lung and Tissue Injury foll ...   Francis, Mary; Groves, Angela M; Sun, Richard; Cervelli, Jessica A; Choi, Hyejeong; Laskin, Je ... P30ES005022, R01ES004738, T32ES007148 Toxicol Sci (2017 02) 27837169 Exiting the NIEHS site 2017 
Editor's Highlight: Role of Spleen-Derived Macrophages in Ozone-Induced Lung Inflammation and Injury ...   Francis, Mary; Sun, Richard; Cervelli, Jessica A; Choi, Hyejeong; Mandal, Mili; Abramova, Elen ... P30ES005022, R01ES004738, T32ES007148 Toxicol Sci (2017 01) 27708193 Exiting the NIEHS site 2017 
Histologic and biochemical alterations predict pulmonary mechanical dysfunction in aging mice with c ...   Massa, Christopher B; Groves, Angela M; Jaggernauth, Smita U; Laskin, Debra L; Gow, Andrew J P30ES005022, R01ES004738, T32ES007148 PLoS Comput Biol (2017 Aug) 28837561 Exiting the NIEHS site 2017 
Regulation of Nitrogen Mustard-Induced Lung Macrophage Activation by Valproic Acid, a Histone Deacet ...   Venosa, Alessandro; Gow, James G; Hall, LeRoy; Malaviya, Rama; Gow, Andrew J; Laskin, Jeffrey ... P30ES005022, R01ES004738 Toxicol Sci (2017 05 01) 28184907 Exiting the NIEHS site 2017 
World Trade Center (WTC) dust exposure in mice is associated with inflammation, oxidative stress and ...   Sunil, Vasanthi R; Vayas, Kinal N; Fang, Mingzhu; Zarbl, Helmut; Massa, Christopher; Gow, Andr ... P30ES005022, R01ES004738, T32ES007148 Exp Mol Pathol (2017 02) 27986442 Exiting the NIEHS site 2017 
Characterization of Distinct Macrophage Subpopulations during Nitrogen Mustard-Induced Lung Injury a ...   Venosa, Alessandro; Malaviya, Rama; Choi, Hyejeong; Gow, Andrew J; Laskin, Jeffrey D; Laskin, ... P30ES005022, R01ES004738 Am J Respir Cell Mol Biol (2016 Mar) 26273949 Exiting the NIEHS site 2016 
Inflammatory mechanisms of pulmonary injury induced by mustards.   Malaviya, Rama; Sunil, Vasanthi R; Venosa, Alessandro; Vayas, Kinal N; Heck, Diane E; Laskin, ... P30ES005022, R01ES004738 Toxicol Lett (2016 Feb 26) 26478570 Exiting the NIEHS site 2016 
Macrophages and inflammatory mediators in pulmonary injury induced by mustard vesicants.   Malaviya, Rama; Sunil, Vasanthi R; Venosa, Alessandro; Vayas, Kinal N; Businaro, Rita; Heck, D ... P30ES005022, R01ES004738 Ann N Y Acad Sci (2016 06) 27351588 Exiting the NIEHS site 2016 
Mitigation of nitrogen mustard mediated skin injury by a novel indomethacin bifunctional prodrug.   Composto, Gabriella M; Laskin, Jeffrey D; Laskin, Debra L; Gerecke, Donald R; Casillas, Robert ... P30ES005022, R01ES004738, T32ES007148 Exp Mol Pathol (2016 Jun) 27189522 Exiting the NIEHS site 2016 
Mustard vesicant-induced lung injury: Advances in therapy.   Weinberger, Barry; Malaviya, Rama; Sunil, Vasanthi R; Venosa, Alessandro; Heck, Diane E; Laskin ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2016 08 15) 27212445 Exiting the NIEHS site 2016 
Mustard vesicants alter expression of the endocannabinoid system in mouse skin.   Wohlman, Irene M; Composto, Gabriella M; Heck, Diane E; Heindel, Ned D; Lacey, C Jeffrey; Guill ... P30ES005022, R01ES004738, T32ES007148 Toxicol Appl Pharmacol (2016 07 15) 27125198 Exiting the NIEHS site 2016 
Nrf2 Regulates the Sensitivity of Mouse Keratinocytes to Nitrogen Mustard via Multidrug Resistance-A ...   Udasin, Ronald G; Wen, Xia; Bircsak, Kristin M; Aleksunes, Lauren M; Shakarjian, Michael P; Kon ... P30ES005022, R01ES004738, T32ES007148 Toxicol Sci (2016 Jan) 26454883 Exiting the NIEHS site 2016 
Selective Targeting of Heme Protein in Cytochrome P450 and Nitric Oxide Synthase by Diphenyleneiodon ...   Szilagyi, John T; Mishin, Vladimir; Heck, Diane E; Jan, Yi-Hua; Aleksunes, Lauren M; Richardson ... P30ES005022, R01ES004738, T32ES007148 Toxicol Sci (2016 05) 26880746 Exiting the NIEHS site 2016 
The spleen as an extramedullary source of inflammatory cells responding to acetaminophen-induced liv ...   Mandal, Mili; Gardner, Carol R; Sun, Richard; Choi, Hyejeong; Lad, Sonali; Mishin, Vladimir; L ... P30ES005022, R01ES004738, T32ES007148 Toxicol Appl Pharmacol (2016 08 01) 27163765 Exiting the NIEHS site 2016 
Attenuation of Nitrogen Mustard-Induced Pulmonary Injury and Fibrosis by Anti-Tumor Necrosis Factor- ...   Malaviya, Rama; Sunil, Vasanthi R; Venosa, Alessandro; Verissimo, Vivianne L; Cervelli, Jessica ... P30ES005022, R01ES004738 Toxicol Sci (2015 Nov) 26243812 Exiting the NIEHS site 2015 
Protective role of spleen-derived macrophages in lung inflammation, injury, and fibrosis induced by ...   Venosa, Alessandro; Malaviya, Rama; Gow, Andrew J; Hall, Leroy; Laskin, Jeffrey D; Laskin, Deb ... P30ES005022, R01ES004738 Am J Physiol Lung Cell Mol Physiol (2015 Dec 15) 26475734 Exiting the NIEHS site 2015 
Radiation-induced lung injury and inflammation in mice: role of inducible nitric oxide synthase and ...   Malaviya, Rama; Gow, Andrew J; Francis, Mary; Abramova, Elena V; Laskin, Jeffrey D; Laskin, De ... P30ES005022, R01ES004738, T32ES007148 Toxicol Sci (2015 Mar) 25552309 Exiting the NIEHS site 2015 
Regulation of ozone-induced lung inflammation and injury by the β-galactoside-binding lectin galecti ...   Sunil, Vasanthi R; Francis, Mary; Vayas, Kinal N; Cervelli, Jessica A; Choi, Hyejeong; Laskin, ... P30ES005022, R01ES004738, T32ES007148 Toxicol Appl Pharmacol (2015 Apr 15) 25724551 Exiting the NIEHS site 2015 
Sulfa drugs inhibit sepiapterin reduction and chemical redox cycling by sepiapterin reductase.   Yang, Shaojun; Jan, Yi-Hua; Mishin, Vladimir; Richardson, Jason R; Hossain, Muhammad M; Heindel ... P30ES005022, R01ES004738 J Pharmacol Exp Ther (2015 Mar) 25550200 Exiting the NIEHS site 2015 
Thioredoxin Cross-Linking by Nitrogen Mustard in Lung Epithelial Cells: Formation of Multimeric Thio ...   Jan, Yi-Hua; Heck, Diane E; Casillas, Robert P; Laskin, Debra L; Laskin, Jeffrey D P30ES005022, R01ES004738 Chem Res Toxicol (2015 Nov 16) 26451472 Exiting the NIEHS site 2015 
Vitamin K3 (menadione) redox cycling inhibits cytochrome P450-mediated metabolism and inhibits parat ...   Jan, Yi-Hua; Richardson, Jason R; Baker, Angela A; Mishin, Vladimir; Heck, Diane E; Laskin, De ... P30ES005022, R01ES004738, T32ES007148 Toxicol Appl Pharmacol (2015 Oct 01) 26212258 Exiting the NIEHS site 2015 
Acetaminophen reactive intermediates target hepatic thioredoxin reductase.   Jan, Yi-Hua; Heck, Diane E; Dragomir, Ana-Cristina; Gardner, Carol R; Laskin, Debra L; Laskin, ... P30ES005022, R01ES004738 Chem Res Toxicol (2014 May 19) 24661219 Exiting the NIEHS site 2014 
Acute chlorine gas exposure produces transient inflammation and a progressive alteration in surfacta ...   Massa, Christopher B; Scott, Pamela; Abramova, Elena; Gardner, Carol; Laskin, Debra L; Gow, An ... P30ES005022, R01ES004738, T32ES007148 Toxicol Appl Pharmacol (2014 Jul 1) 24582687 Exiting the NIEHS site 2014 
Critical role of the endogenous interferon ligand-receptors in type I and type II interferons respon ...   Lasfar, Ahmed; Cook, Jeffry R; Cohen Solal, Karine A; Reuhl, Kenneth; Kotenko, Sergei V; Langer ... P30ES005022, R01ES004738 Immunology (2014 Jul) 24597649 Exiting the NIEHS site 2014 
Cross-linking of thioredoxin reductase by the sulfur mustard analogue mechlorethamine (methylbis(2-c ...   Jan, Yi-Hua; Heck, Diane E; Malaviya, Rama; Casillas, Robert P; Laskin, Debra L; Laskin, Jeffr ... P30ES005022, R01ES004738 Chem Res Toxicol (2014 Jan 21) 24274902 Exiting the NIEHS site 2014 
Differential metabolism of 4-hydroxynonenal in liver, lung and brain of mice and rats.   Zheng, Ruijin; Dragomir, Ana-Cristina; Mishin, Vladimir; Richardson, Jason R; Heck, Diane E; La ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2014 Aug 15) 24832492 Exiting the NIEHS site 2014 
Human recombinant cytochrome P450 enzymes display distinct hydrogen peroxide generating activities d ...   Mishin, Vladimir; Heck, Diane E; Laskin, Debra L; Laskin, Jeffrey D P30ES005022, R01ES004738 Toxicol Sci (2014 Oct) 25061110 Exiting the NIEHS site 2014 
Modulation of keratinocyte expression of antioxidants by 4-hydroxynonenal, a lipid peroxidation end ...   Zheng, Ruijin; Heck, Diane E; Mishin, Vladimir; Black, Adrienne T; Shakarjian, Michael P; Kong, ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2014 Mar 1) 24423726 Exiting the NIEHS site 2014 
Oxidative stress-induced autophagy: role in pulmonary toxicity.   Malaviya, Rama; Laskin, Jeffrey D; Laskin, Debra L P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2014 Mar 1) 24398106 Exiting the NIEHS site 2014 
Pentoxifylline attenuates nitrogen mustard-induced acute lung injury, oxidative stress and inflammat ...   Sunil, Vasanthi R; Vayas, Kinal N; Cervelli, Jessica A; Malaviya, Rama; Hall, LeRoy; Massa, Ch ... P30ES005022, R01ES004738, T32ES007148 Exp Mol Pathol (2014 Aug) 24886962 Exiting the NIEHS site 2014 
Regulation of keratinocyte expression of stress proteins and antioxidants by the electrophilic nitro ...   Zheng, Ruijin; Heck, Diane E; Black, Adrienne T; Gow, Andrew; Laskin, Debra L; Laskin, Jeffrey ... P30ES005022, R01ES004738 Free Radic Biol Med (2014 Feb) 24140437 Exiting the NIEHS site 2014 
Structural changes in hair follicles and sebaceous glands of hairless mice following exposure to sul ...   Joseph, Laurie B; Heck, Diane E; Cervelli, Jessica A; Composto, Gabriella M; Babin, Michael C; ... P30ES005022, R01ES004738, T32ES007148 Exp Mol Pathol (2014 Jun) 24662110 Exiting the NIEHS site 2014 
Therapeutic potential of a non-steroidal bifunctional anti-inflammatory and anti-cholinergic agent a ...   Chang, Yoke-Chen; Wang, James D; Hahn, Rita A; Gordon, Marion K; Joseph, Laurie B; Heck, Diane ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2014 Oct 15) 25127551 Exiting the NIEHS site 2014 
Age-related increases in ozone-induced injury and altered pulmonary mechanics in mice with progressi ...   Groves, Angela M; Gow, Andrew J; Massa, Christopher B; Hall, LeRoy; Laskin, Jeffrey D; Laskin, ... P30ES005022, R01ES004738, T32ES007148 Am J Physiol Lung Cell Mol Physiol (2013 Oct 15) 23997172 Exiting the NIEHS site 2013 
Classical and alternative activation of rat hepatic sinusoidal endothelial cells by inflammatory sti ...   Liu, Yinglin; Gardner, Carol R; Laskin, Jeffrey D; Laskin, Debra L P30ES005022, R01ES004738 Exp Mol Pathol (2013 Feb) 23103612 Exiting the NIEHS site 2013 
Distinct responses of lung and liver macrophages to acute endotoxemia: role of toll-like receptor 4.   Connor, Agnieszka J; Chen, Li C; Joseph, Laurie B; Laskin, Jeffrey D; Laskin, Debra L P30ES005022, R01ES004738, T32ES007148 Exp Mol Pathol (2013 Feb) 23000425 Exiting the NIEHS site 2013 
Optimization of cell receptor-specific targeting through multivalent surface decoration of polymeric ...   D'Addio, Suzanne M; Baldassano, Steven; Shi, Lei; Cheung, Lila; Adamson, Douglas H; Bruzek, Ma ... P30ES005022, R01ES004738 J Control Release (2013 May 28) 23419950 Exiting the NIEHS site 2013 
Ozone-induced injury and oxidative stress in bronchiolar epithelium are associated with altered pulm ...   Sunil, Vasanthi R; Vayas, Kinal N; Massa, Christopher B; Gow, Andrew J; Laskin, Jeffrey D; Lask ... P30ES005022, R01ES004738, T32ES007148 Toxicol Sci (2013 Jun) 23492811 Exiting the NIEHS site 2013 
Sepiapterin reductase mediates chemical redox cycling in lung epithelial cells.   Yang, Shaojun; Jan, Yi-Hua; Gray, Joshua P; Mishin, Vladimir; Heck, Diane E; Laskin, Debra L; ... P30ES005022, R01ES004738 J Biol Chem (2013 Jun 28) 23640889 Exiting the NIEHS site 2013 
The generation of 4-hydroxynonenal, an electrophilic lipid peroxidation end product, in rabbit corne ...   Zheng, Ruijin; Po, Iris; Mishin, Vladimir; Black, Adrienne T; Heck, Diane E; Laskin, Debra L; ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2013 Oct 15) 23845594 Exiting the NIEHS site 2013 
Toxicodynamics of rigid polystyrene microparticles on pulmonary gas exchange in mice: implications f ...   Kutscher, H L; Gao, D; Li, S; Massa, C B; Cervelli, J; Deshmukh, M; Joseph, L B; Laskin, D L ... P30ES005022, R01ES004738, T32ES007148 Toxicol Appl Pharmacol (2013 Jan 15) 23142466 Exiting the NIEHS site 2013 
Attenuation of acute nitrogen mustard-induced lung injury, inflammation and fibrogenesis by a nitric ...   Malaviya, Rama; Venosa, Alessandro; Hall, Leroy; Gow, Andrew J; Sinko, Patrick J; Laskin, Jeff ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2012 Dec 15) 22981630 Exiting the NIEHS site 2012 
Biodistribution and renal clearance of biocompatible lung targeted poly(ethylene glycol) (PEG) nanog ...   Deshmukh, Manjeet; Kutscher, Hilliard L; Gao, Dayuan; Sunil, Vasanthi R; Malaviya, Rama; Vayas, ... P30ES005022, R01ES004738 J Control Release (2012 Nov 28) 23041417 Exiting the NIEHS site 2012 
Classical and alternative macrophage activation in the lung following ozone-induced oxidative stress ...   Sunil, Vasanthi R; Patel-Vayas, Kinal; Shen, Jianliang; Laskin, Jeffrey D; Laskin, Debra L P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2012 Sep 01) 22727909 Exiting the NIEHS site 2012 
Exacerbation of acetaminophen hepatotoxicity by the anthelmentic drug fenbendazole.   Gardner, Carol R; Mishin, Vladimir; Laskin, Jeffrey D; Laskin, Debra L P30ES005022, R01ES004738 Toxicol Sci (2012 Feb) 22048645 Exiting the NIEHS site 2012 
Ozone-induced lung injury and sterile inflammation. Role of toll-like receptor 4.   Connor, Agnieszka J; Laskin, Jeffrey D; Laskin, Debra L P30ES005022, R01ES004738, T32ES007148 Exp Mol Pathol (2012 Apr) 22300504 Exiting the NIEHS site 2012 
Prolonged injury and altered lung function after ozone inhalation in mice with chronic lung inflamma ...   Groves, Angela M; Gow, Andrew J; Massa, Christopher B; Laskin, Jeffrey D; Laskin, Debra L P30ES005022, R01ES004738, T32ES007148 Am J Respir Cell Mol Biol (2012 Dec) 22878412 Exiting the NIEHS site 2012 
Regulation of alternative macrophage activation in the liver following acetaminophen intoxication by ...   Gardner, Carol R; Hankey, Pamela; Mishin, Vladimir; Francis, Mary; Yu, Shan; Laskin, Jeffrey D ... P30ES005022, R01ES004738, T32ES007148 Toxicol Appl Pharmacol (2012 Jul 15) 22575169 Exiting the NIEHS site 2012 
Role of galectin-3 in acetaminophen-induced hepatotoxicity and inflammatory mediator production.   Dragomir, Ana-Cristina; Sun, Richard; Mishin, Vladimir; Hall, LeRoy B; Laskin, Jeffrey D; Laski ... P30ES005022, R01ES004738 Toxicol Sci (2012 Jun) 22461450 Exiting the NIEHS site 2012 
Role of galectin-3 in classical and alternative macrophage activation in the liver following acetami ...   Dragomir, Ana-Cristina Docan; Sun, Richard; Choi, Hyejeong; Laskin, Jeffrey D; Laskin, Debra L P30ES005022, R01ES004738 J Immunol (2012 Dec 15) 23175698 Exiting the NIEHS site 2012 
Role of reactive nitrogen species generated via inducible nitric oxide synthase in vesicant-induced ...   Sunil, Vasanthi R; Shen, Jianliang; Patel-Vayas, Kinal; Gow, Andrew J; Laskin, Jeffrey D; Laski ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2012 May 15) 22446026 Exiting the NIEHS site 2012 
Acute decreases in proteasome pathway activity after inhalation of fresh diesel exhaust or secondary ...   Kipen, Howard M; Gandhi, Sampada; Rich, David Q; Ohman-Strickland, Pamela; Laumbach, Robert; Fa ... P30ES005022, R01ES004738 Environ Health Perspect (2011 May) 21163722 Exiting the NIEHS site 2011 
Functional and inflammatory alterations in the lung following exposure of rats to nitrogen mustard.   Sunil, Vasanthi R; Patel, Kinal J; Shen, Jianliang; Reimer, David; Gow, Andrew J; Laskin, Jeff ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2011 Jan 01) 20883710 Exiting the NIEHS site 2011 
Macrophage activation by factors released from acetaminophen-injured hepatocytes: potential role of ...   Dragomir, Ana-Cristina; Laskin, Jeffrey D; Laskin, Debra L P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2011 Jun 15) 21513726 Exiting the NIEHS site 2011 
Macrophages and tissue injury: agents of defense or destruction?   Laskin, Debra L; Sunil, Vasanthi R; Gardner, Carol R; Laskin, Jeffrey D P30ES005022, R01ES004738 Annu Rev Pharmacol Toxicol (2011) 20887196 Exiting the NIEHS site 2011 
Redox cycling and increased oxygen utilization contribute to diquat-induced oxidative stress and cyt ...   Fussell, Karma C; Udasin, Ronald G; Gray, Joshua P; Mishin, Vladimir; Smith, Peter J S; Heck, ... P30ES005022, R01ES004738, T32ES007148 Free Radic Biol Med (2011 Apr 01) 21215309 Exiting the NIEHS site 2011 
Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae follow ...   Black, Adrienne T; Hayden, Patrick J; Casillas, Robert P; Heck, Diane E; Gerecke, Donald R; Sin ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2011 Jun 1) 21457723 Exiting the NIEHS site 2011 
Role of protein transamidation in serotonin-induced proliferation and migration of pulmonary artery ...   Liu, Yinglin; Wei, Lin; Laskin, Debra L; Fanburg, Barry L P30ES005022, R01ES004738 Am J Respir Cell Mol Biol (2011 Apr) 20558776 Exiting the NIEHS site 2011 
Role of TNFR1 in lung injury and altered lung function induced by the model sulfur mustard vesicant, ...   Sunil, Vasanthi R; Patel-Vayas, Kinal; Shen, Jianliang; Gow, Andrew J; Laskin, Jeffrey D; Laski ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2011 Feb 1) 21070800 Exiting the NIEHS site 2011 
Structural changes in the skin of hairless mice following exposure to sulfur mustard correlate with ...   Joseph, Laurie B; Gerecke, Donald R; Heck, Diane E; Black, Adrienne T; Sinko, Patrick J; Cervel ... P30ES005022, R01ES004738 Exp Mol Pathol (2011 Oct) 21672537 Exiting the NIEHS site 2011 
Sulfur mustard-induced pulmonary injury: therapeutic approaches to mitigating toxicity.   Weinberger, Barry; Laskin, Jeffrey D; Sunil, Vasanthi R; Sinko, Patrick J; Heck, Diane E; Laski ... P30ES005022, R01ES004738 Pulm Pharmacol Ther (2011 Feb) 20851203 Exiting the NIEHS site 2011 
UVB light regulates expression of antioxidants and inflammatory mediators in human corneal epithelia ...   Black, Adrienne T; Gordon, Marion K; Heck, Diane E; Gallo, Michael A; Laskin, Debra L; Laskin, ... P30ES005022, R01ES004738 Biochem Pharmacol (2011 Apr 01) 21300015 Exiting the NIEHS site 2011 
Application of the Amplex red/horseradish peroxidase assay to measure hydrogen peroxide generation b ...   Mishin, Vladimir; Gray, Joshua P; Heck, Diane E; Laskin, Debra L; Laskin, Jeffrey D P30ES005022, R01ES004738 Free Radic Biol Med (2010 Jun 01) 20188819 Exiting the NIEHS site 2010 
Distinct roles of cytochrome P450 reductase in mitomycin C redox cycling and cytotoxicity.   Wang, Yun; Gray, Joshua P; Mishin, Vladimir; Heck, Diane E; Laskin, Debra L; Laskin, Jeffrey D P30ES005022, R01ES004738 Mol Cancer Ther (2010 Jun) 20501808 Exiting the NIEHS site 2010 
Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent follo ...   Black, Adrienne T; Hayden, Patrick J; Casillas, Robert P; Heck, Diane E; Gerecke, Donald R; Sin ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2010 Dec 01) 20840853 Exiting the NIEHS site 2010 
Inflammatory effects of inhaled sulfur mustard in rat lung.   Malaviya, Rama; Sunil, Vasanthi R; Cervelli, Jessica; Anderson, Dana R; Holmes, Wesley W; Conti ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2010 Oct 15) 20659490 Exiting the NIEHS site 2010 
Inflammatory effects of phthalates in neonatal neutrophils.   Vetrano, Anna M; Laskin, Debra L; Archer, Faith; Syed, Kirin; Gray, Joshua P; Laskin, Jeffrey ... P30ES005022, R01ES004738 Pediatr Res (2010 Aug) 20453712 Exiting the NIEHS site 2010 
Inhibition of NADPH cytochrome P450 reductase by the model sulfur mustard vesicant 2-chloroethyl eth ...   Gray, Joshua P; Mishin, Vladimir; Heck, Diane E; Laskin, Debra L; Laskin, Jeffrey D P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2010 Sep 01) 20561902 Exiting the NIEHS site 2010 
Janus kinase-3 dependent inflammatory responses in allergic asthma.   Malaviya, Rama; Laskin, Debra L; Malaviya, Ravi P30ES005022, R01ES004738 Int Immunopharmacol (2010 Aug) 20430118 Exiting the NIEHS site 2010 
Macrophages, reactive nitrogen species, and lung injury.   Laskin, Debra L; Sunil, Vasanthi R; Fakhrzadeh, Ladan; Groves, Angela; Gow, Andrew J; Laskin, ... P30ES005022, R01ES004738, T32ES007148 Ann N Y Acad Sci (2010 Aug) 20716284 Exiting the NIEHS site 2010 
Mechanisms mediating the vesicant actions of sulfur mustard after cutaneous exposure.   Shakarjian, Michael P; Heck, Diane E; Gray, Joshua P; Sinko, Patrick J; Gordon, Marion K; Casil ... P30ES005022, R01ES004738 Toxicol Sci (2010 Mar) 19833738 Exiting the NIEHS site 2010 
Oxidants and antioxidants in sulfur mustard-induced injury.   Laskin, Jeffrey D; Black, Adrienne T; Jan, Yi-Hua; Sinko, Patrick J; Heindel, Ned D; Sunil, Va ... P30ES005022, R01ES004738, T32ES007148 Ann N Y Acad Sci (2010 Aug) 20716289 Exiting the NIEHS site 2010 
Potential role of caveolin-1 in acetaminophen-induced hepatotoxicity.   Gardner, Carol R; Gray, Joshua P; Joseph, Laurie B; Cervelli, Jessica; Bremer, Nicole; Kim, Yu ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2010 May 15) 20100502 Exiting the NIEHS site 2010 
Pulmonary effects of inhaled diesel exhaust in young and old mice: a pilot project.   Laskin, Debra L; Mainelis, Gediminas; Turpin, Barbara J; Patel, Kinal J; Sunil, Vasanthi R; HEI ... P30ES005022, R01ES004738 Res Rep Health Eff Inst (2010 Sep) 21381634 Exiting the NIEHS site 2010 
Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse ker ...   Black, Adrienne T; Joseph, Laurie B; Casillas, Robert P; Heck, Diane E; Gerecke, Donald R; Sink ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2010 Jun 15) 20382172 Exiting the NIEHS site 2010 
Role of STK in mouse liver macrophage and endothelial cell responsiveness during acute endotoxemia.   Laskin, Debra L; Chen, Li; Hankey, Pamela A; Laskin, Jeffrey D P30ES005022, R01ES004738 J Leukoc Biol (2010 Aug) 20453108 Exiting the NIEHS site 2010 
Selective targeting of selenocysteine in thioredoxin reductase by the half mustard 2-chloroethyl eth ...   Jan, Yi-Hua; Heck, Diane E; Gray, Joshua P; Zheng, Haiyan; Casillas, Robert P; Laskin, Debra L ... P30ES005022, R01ES004738, T32ES007148 Chem Res Toxicol (2010 Jun 21) 20345183 Exiting the NIEHS site 2010 
Differential gene expression profiling of mouse skin after sulfur mustard exposure: Extended time re ...   Gerecke, Donald R; Chen, Minjun; Isukapalli, Sastry S; Gordon, Marion K; Chang, Yoke-Chen; Tong ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2009 Jan 15) 18955075 Exiting the NIEHS site 2009 
Macrophages and inflammatory mediators in chemical toxicity: a battle of forces.   Laskin, Debra L P30ES005022, R01ES004738 Chem Res Toxicol (2009 Aug) 19645497 Exiting the NIEHS site 2009 
Nitrative and oxidative stress in toxicology and disease.   Roberts, Ruth A; Laskin, Debra L; Smith, Charles V; Robertson, Fredika M; Allen, Erin M G; Door ... P30ES005022, R01ES004738 Toxicol Sci (2009 Nov) 19656995 Exiting the NIEHS site 2009 
Pulmonary effects of inhaled diesel exhaust in aged mice.   Sunil, Vasanthi R; Patel, Kinal J; Mainelis, Gediminas; Turpin, Barbara J; Ridgely, Sherritta; ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2009 Dec 15) 19729031 Exiting the NIEHS site 2009 
Upregulation of gamma-2 laminin-332 in the mouse ear vesicant wound model.   Chang, Yoke-Chen; Sabourin, Carol L K; Lu, Shou-En; Sasaki, Takako; Svoboda, Kathy K H; Gordon, ... P30ES005022, R01ES004738 J Biochem Mol Toxicol (2009 May-Jun) 19526566 Exiting the NIEHS site 2009 
Distinct effects of ultraviolet B light on antioxidant expression in undifferentiated and differenti ...   Black, Adrienne T; Gray, Joshua P; Shakarjian, Michael P; Laskin, Debra L; Heck, Diane E; Laski ... P30ES005022, R01ES004738 Carcinogenesis (2008 Jan) 17984112 Exiting the NIEHS site 2008 
Increased oxidative stress and antioxidant expression in mouse keratinocytes following exposure to p ...   Black, Adrienne T; Gray, Joshua P; Shakarjian, Michael P; Laskin, Debra L; Heck, Diane E; Laski ... P30ES005022, R01ES004738, T32ES007148 Toxicol Appl Pharmacol (2008 Sep 15) 18620719 Exiting the NIEHS site 2008 
Mechanisms mediating reduced responsiveness of neonatal neutrophils to lipoxin A4.   Weinberger, Barry; Quizon, Cecile; Vetrano, Anna M; Archer, Faith; Laskin, Jeffrey D; Laskin, ... P30ES005022, R01ES004738 Pediatr Res (2008 Oct) 18535486 Exiting the NIEHS site 2008 
Regulation of caveolin-1 expression, nitric oxide production and tissue injury by tumor necrosis fac ...   Fakhrzadeh, Ladan; Laskin, Jeffrey D; Laskin, Debra L P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2008 Mar 15) 18207479 Exiting the NIEHS site 2008 
Regulation of TREM expression in hepatic macrophages and endothelial cells during acute endotoxemia.   Chen, Li C; Laskin, Jeffrey D; Gordon, Marion K; Laskin, Debra L P30ES005022, R01ES004738 Exp Mol Pathol (2008 Apr) 18222421 Exiting the NIEHS site 2008 
Role of cytochrome P450 reductase in nitrofurantoin-induced redox cycling and cytotoxicity.   Wang, Yun; Gray, Joshua P; Mishin, Vladimir; Heck, Diane E; Laskin, Debra L; Laskin, Jeffrey D P30ES005022, R01ES004738 Free Radic Biol Med (2008 Mar 15) 18206659 Exiting the NIEHS site 2008 
UVB light upregulates prostaglandin synthases and prostaglandin receptors in mouse keratinocytes.   Black, Adrienne T; Gray, Joshua P; Shakarjian, Michael P; Mishin, Vladimir; Laskin, Debra L; He ... P30ES005022, R01ES004738, T32ES007148 Toxicol Appl Pharmacol (2008 Oct 01) 18597804 Exiting the NIEHS site 2008 
Acute endotoxemia is associated with upregulation of lipocalin 24p3/Lcn2 in lung and liver.   Sunil, Vasanthi R; Patel, Kinal J; Nilsen-Hamilton, Marit; Heck, Diane E; Laskin, Jeffrey D; La ... P30ES005022, R01ES004738 Exp Mol Pathol (2007 Oct) 17490638 Exiting the NIEHS site 2007 
Influence of labor on neonatal neutrophil apoptosis, and inflammatory activity.   Weinberger, Barry; Vetrano, Anna M; Syed, Kirin; Murthy, Sowmya; Hanna, Nazeeh; Laskin, Jeffre ... P30ES005022, R01ES004738 Pediatr Res (2007 May) 17413861 Exiting the NIEHS site 2007 
Paraquat increases cyanide-insensitive respiration in murine lung epithelial cells by activating an ...   Gray, Joshua P; Heck, Diane E; Mishin, Vladimir; Smith, Peter J S; Hong, Jun-Yan; Thiruchelvam, ... P30ES005022, R01ES004738 J Biol Chem (2007 Mar 16) 17229725 Exiting the NIEHS site 2007 
Pulmonary effects of inhaled limonene ozone reaction products in elderly rats.   Sunil, Vasanthi R; Laumbach, Robert J; Patel, Kinal J; Turpin, Barbara J; Lim, Ho-Jin; Kipen, ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2007 Jul 15) 17610924 Exiting the NIEHS site 2007 
Role of TLR-4 in liver macrophage and endothelial cell responsiveness during acute endotoxemia.   Chen, Li C; Gordon, Ronald E; Laskin, Jeffrey D; Laskin, Debra L P30ES005022, R01ES004738 Exp Mol Pathol (2007 Dec) 17996232 Exiting the NIEHS site 2007 
Distinct roles of NF-kappaB p50 in the regulation of acetaminophen-induced inflammatory mediator pro ...   Dambach, Donna M; Durham, Stephen K; Laskin, Jeffrey D; Laskin, Debra L P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2006 Mar 1) 16081117 Exiting the NIEHS site 2006 
Characterization of the oxidase activity in mammalian catalase.   Vetrano, Anna M; Heck, Diane E; Mariano, Thomas M; Mishin, Vladimir; Laskin, Debra L; Laskin, ... P30ES005022, R01ES004738 J Biol Chem (2005 Oct 21) 16079130 Exiting the NIEHS site 2005 
Inhibition of interferon-gamma signaling by a mercurio-substituted dihydropsoralen in murine keratin ...   Martey, Christine A; Vetrano, Anna M; Whittemore, Marilyn S; Mariano, Thomas M; Heck, Diane E; ... P30ES005022, R01ES004738 Biochem Pharmacol (2005 Dec 5) 16259964 Exiting the NIEHS site 2005 
Mechanisms mediating the biologic activity of synthetic proline, glycine, and hydroxyproline polypep ...   Weinberger, Barry; Hanna, Nazeeh; Laskin, Jeffrey D; Heck, Diane E; Gardner, Carol R; Gerecke, ... P30ES005022, R01ES004738 Mediators Inflamm (2005 Feb 24) 15770064 Exiting the NIEHS site 2005 
Mechanisms underlying reduced apoptosis in neonatal neutrophils.   Hanna, Nazeeh; Vasquez, Pedro; Pham, Petra; Heck, Diane E; Laskin, Jeffrey D; Laskin, Debra L; ... P30ES005022, R01ES004738 Pediatr Res (2005 Jan) 15557111 Exiting the NIEHS site 2005 
Ozone-induced production of nitric oxide and TNF-alpha and tissue injury are dependent on NF-kappaB ...   Fakhrzadeh, Ladan; Laskin, Jeffrey D; Laskin, Debra L P30ES005022, R01ES004738 Am J Physiol Lung Cell Mol Physiol (2004 Aug) 15064226 Exiting the NIEHS site 2004 
Solar ultraviolet radiation as a trigger of cell signal transduction.   Heck, Diane E; Gerecke, Donald R; Vetrano, Anna M; Laskin, Jeffrey D P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2004 Mar 15) 15020191 Exiting the NIEHS site 2004 
Superoxide dismutase-overexpressing mice are resistant to ozone-induced tissue injury and increases ...   Fakhrzadeh, Ladan; Laskin, Jeffrey D; Gardner, Carol R; Laskin, Debra L P30ES005022, R01ES004738 Am J Respir Cell Mol Biol (2004 Mar) 12855403 Exiting the NIEHS site 2004 
Exaggerated hepatotoxicity of acetaminophen in mice lacking tumor necrosis factor receptor-1. Potent ...   Gardner, Carol R; Laskin, Jeffrey D; Dambach, Donna M; Chiu, Hawjyh; Durham, Stephen K; Zhou, ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2003 Oct 15) 14550746 Exiting the NIEHS site 2003 
Role of p55 tumor necrosis factor receptor 1 in acetaminophen-induced antioxidant defense.   Chiu, Hawjyh; Gardner, Carol R; Dambach, Donna M; Brittingham, Jennie A; Durham, Stephen K; Las ... P30ES005022, R01ES004738 Am J Physiol Gastrointest Liver Physiol (2003 Nov) 12842828 Exiting the NIEHS site 2003 
Role of tumor necrosis factor receptor 1 (p55) in hepatocyte proliferation during acetaminophen-indu ...   Chiu, Hawjyh; Gardner, Carol R; Dambach, Donna M; Durham, Stephen K; Brittingham, Jennie A; Las ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2003 Dec 01) 14644624 Exiting the NIEHS site 2003 
Activation of adherent vascular neutrophils in the lung during acute endotoxemia.   Sunil, Vasanthi R; Connor, Agnieszka J; Zhou, Peihong; Gordon, Marion K; Laskin, Jeffrey D; Las ... P30ES005022, R01ES004738, T32ES007148 Respir Res (2002) 12204102 Exiting the NIEHS site 2002 
Activation of type II alveolar epithelial cells during acute endotoxemia.   Sunil, Vasanthi R; Connor, Agnieszka J; Guo, Yan; Laskin, Jeffrey D; Laskin, Debra L P30ES005022, R01ES004738, T32ES007148 Am J Physiol Lung Cell Mol Physiol (2002 Apr) 11880315 Exiting the NIEHS site 2002 
Acute endotoxemia prolongs the survival of rat lung neutrophils in response to 12-O-tetradecanoyl-ph ...   Sunil, Vasanthi R; Connor, Agnieszka J; Lavnikova, Natasha; Gardner, Carol R; Laskin, Jeffrey D ... P30ES005022, R01ES004738, T32ES007148 J Cell Physiol (2002 Mar) 11857454 Exiting the NIEHS site 2002 
Deficiency in inducible nitric oxide synthase protects mice from ozone-induced lung inflammation and ...   Fakhrzadeh, Ladan; Laskin, Jeffrey D; Laskin, Debra L P30ES005022, R01ES004738 Am J Respir Cell Mol Biol (2002 Apr) 11919077 Exiting the NIEHS site 2002 
Differential induction of heme oxygenase-1 in macrophages and hepatocytes during acetaminophen-induc ...   Chiu, Hawjyh; Brittingham, Jennie A; Laskin, Debra L P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2002 Jun 1) 12051994 Exiting the NIEHS site 2002 
Induction of cyclooxygenase-2 by heat shock protein 60 in macrophages and endothelial cells.   Billack, Blase; Heck, Diane E; Mariano, Thomas M; Gardner, Carol R; Sur, Runa; Laskin, Debra L ... P30ES005022, R01ES004738 Am J Physiol Cell Physiol (2002 Oct) 12225989 Exiting the NIEHS site 2002 
Reduced hepatotoxicity of acetaminophen in mice lacking inducible nitric oxide synthase: potential r ...   Gardner, Carol R; Laskin, Jeffrey D; Dambach, Donna M; Sacco, Michael; Durham, Stephen K; Bruno ... P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2002 Oct 1) 12392966 Exiting the NIEHS site 2002 
Regulation of cyclooxygenase-2 by nitric oxide in activated hepatic macrophages during acute endotox ...   Ahmad, Nosheen; Chen, Li C; Gordon, Marion A; Laskin, Jeffrey D; Laskin, Debra L P30ES005022, R01ES004738 J Leukoc Biol (2002 Jun) 12050186 Exiting the NIEHS site 2002 
Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in t ...   Dambach, Donna M; Watson, Linda M; Gray, Kevin R; Durham, Stephen K; Laskin, Debra L P30ES005022, R01ES004738 Hepatology (2002 May) 11981759 Exiting the NIEHS site 2002 
Upregulation of phosphoinositide 3-kinase and protein kinase B in alveolar macrophages following ozo ...   Laskin, Debra L; Fakhrzadeh, Ladan; Heck, Diane E; Gerecke, Donald; Laskin, Jeffrey D P30ES005022, R01ES004738 Mol Cell Biochem (2002 May-Jun) 12162464 Exiting the NIEHS site 2002 
Functional heterogeneity in liver and lung macrophages.   Laskin, D L; Weinberger, B; Laskin, J D R01ES004738 J Leukoc Biol (2001 Aug) 11493607 Exiting the NIEHS site 2001 
Mechanisms underlying reduced responsiveness of neonatal neutrophils to distinct chemoattractants.   Weinberger, B; Laskin, D L; Mariano, T M; Sunil, V R; DeCoste, C J; Heck, D E; Gardner, C R; ... P30ES005022, R01ES004738 J Leukoc Biol (2001 Dec) 11739560 Exiting the NIEHS site 2001 
Nitric oxide and peroxynitrite in ozone-induced lung injury.   Laskin, D L; Fakhrzadeh, L; Laskin, J D R01ES004738 Adv Exp Med Biol (2001) 11764933 Exiting the NIEHS site 2001 
Prooxidant and antioxidant functions of nitric oxide in liver toxicity.   Laskin, J D; Heck, D E; Gardner, C R; Laskin, D L P30ES005022, R01ES004738 Antioxid Redox Signal (2001 Apr) 11396480 Exiting the NIEHS site 2001 
Role of macrophages and inflammatory mediators in chemically induced toxicity.   Laskin, D L; Laskin, J D P30ES005022, R01ES004738 Toxicology (2001 Mar 07) 11246131 Exiting the NIEHS site 2001 
The toxicology of inhaled nitric oxide.   Weinberger, B; Laskin, D L; Heck, D E; Laskin, J D R01ES004738 Toxicol Sci (2001 Jan) 11134540 Exiting the NIEHS site 2001 
Tissue injury following inhalation of fine particulate matter and hydrogen peroxide is associated wi ...   Morio, L A; Hooper, K A; Brittingham, J; Li, T H; Gordon, R E; Turpin, B J; Laskin, D L P30ES005022, R01ES004738 Toxicol Appl Pharmacol (2001 Dec 15) 11749118 Exiting the NIEHS site 2001 
Functional heterogeneity of rat hepatic and alveolar macrophages: effects of chronic ethanol adminis ...   Morio, L A; Chiu, H; Sprowles, K A; Laskin, D L R01ES004738 J Leukoc Biol (2000 Nov) 11073098 Exiting the NIEHS site 2000 
Distinct inflammatory responses of adherent vascular lung neutrophils to pulmonary irritants.   Lavnikova, N; Prokhorova, S; Lakhotia, A V; Gordon, R; Laskin, D L P30ES005022, R01ES004738 J Inflamm (1998) 9656142 Exiting the NIEHS site 1998 
Increased nitric oxide synthase in the lung after ozone inhalation is associated with activation of ...   Laskin, D L; Sunil, V; Guo, Y; Heck, D E; Laskin, J D P30ES005022, R01ES004738 Environ Health Perspect (1998 Oct) 9788894 Exiting the NIEHS site 1998 
Inhaled nitric oxide primes lung macrophages to produce reactive oxygen and nitrogen intermediates.   Weinberger, B; Fakhrzadeh, L; Heck, D E; Laskin, J D; Gardner, C R; Laskin, D L P30ES005022, R01ES004738 Am J Respir Crit Care Med (1998 Sep) 9731028 Exiting the NIEHS site 1998 
Role of inflammatory cytokines and nitric oxide in hepatic and pulmonary toxicity.   Laskin, D L; Heck, D E; Laskin, J D R01ES004738 Toxicol Lett (1998 Dec 28) 10022268 Exiting the NIEHS site 1998 
Macrophage and interleukin-1 induced nitric oxide production and cytostasis in hamster tumor cells v ...   Lavnikova, N; Burdelya, L; Lakhotia, A; Patel, N; Prokhorova, S; Laskin, D L P30ES005022, R01ES004738 J Leukoc Biol (1997 Apr) 9103232 Exiting the NIEHS site 1997 
Cytostasis is required for IL-1 induced nitric oxide production in transformed hamster fibroblasts.   Lavnikova, N; Lakhotia, A; Patel, N; Prokhorova, S; Laskin, D L P30ES005022, R01ES004738 J Cell Physiol (1996 Dec) 8952702 Exiting the NIEHS site 1996 
Inhibition of ozone-induced nitric oxide synthase expression in the lung by endotoxin.   Pendino, K J; Gardner, C R; Shuler, R L; Laskin, J D; Durham, S K; Barton, D S; Ohnishi, S T; ... P30ES005022, R01ES004738 Am J Respir Cell Mol Biol (1996 Jun) 8652180 Exiting the NIEHS site 1996 
Mechanisms regulating macrophage-induced nitric oxide production by spontaneously transformed hamste ...   Lavnikova, N; Prokhorova, S; Burdelia, L; Lakhotia, A; Laskin, D L P30ES005022, R01ES004738 J Leukoc Biol (1996 Oct) 8864131 Exiting the NIEHS site 1996 
Role of nitric oxide in hematosuppression and benzene-induced toxicity.   Laskin, D L; Heck, D E; Punjabi, C J; Laskin, J D R01ES004738 Environ Health Perspect (1996 Dec) 9118907 Exiting the NIEHS site 1996 
Stimulation of nitric oxide production in rat lung lavage cells by anti-Mac-1beta antibody: effects ...   Pendino, K J; Gardner, C R; Quinones, S; Laskin, D L P30ES005022, R01ES004738 Am J Respir Cell Mol Biol (1996 Apr) 8600936 Exiting the NIEHS site 1996 
Hepatic nitric oxide production following acute endotoxemia in rats is mediated by increased inducib ...   Laskin, D L; Rodriguez del Valle, M; Heck, D E; Hwang, S M; Ohnishi, S T; Durham, S K; Goller, ... P30ES005022, R01ES004738 Hepatology (1995 Jul) 7541386 Exiting the NIEHS site 1995 
Inhibition of macrophages with gadolinium chloride abrogates ozone-induced pulmonary injury and infl ...   Pendino, K J; Meidhof, T M; Heck, D E; Laskin, J D; Laskin, D L P30ES005022, R01ES004738 Am J Respir Cell Mol Biol (1995 Aug) 7542894 Exiting the NIEHS site 1995 
Macrophages and inflammatory mediators in tissue injury.   Laskin, D L; Pendino, K J P30ES005022, R01ES004738 Annu Rev Pharmacol Toxicol (1995) 7598511 Exiting the NIEHS site 1995 
Taurine protects rat bronchioles from acute ozone-induced lung inflammation and hyperplasia.   Schuller-Levis, G B; Gordon, R E; Park, E; Pendino, K J; Laskin, D L R01ES004738 Exp Lung Res (1995 Nov-Dec) 8591791 Exiting the NIEHS site 1995 
Unique patterns of regulation of nitric oxide production in fibroblasts.   Lavnikova, N; Laskin, D L P30ES005022, R01ES004738 J Leukoc Biol (1995 Oct) 7561522 Exiting the NIEHS site 1995 
Activation of alveolar macrophages by native and synthetic collagen-like polypeptides.   Laskin, D L; Soltys, R A; Berg, R A; Riley, D J R01ES004738 Am J Respir Cell Mol Biol (1994 Jan) 8292381 Exiting the NIEHS site 1994 
Alterations in expression of p56lck during myeloid differentiation of LSTRA cells.   Garcia-Welsh, A; Laskin, D L; Molloy, C J; Laskin, J D P30ES005022, R01ES004738 Cell Growth Differ (1994 Nov) 7531490 Exiting the NIEHS site 1994 
Cellular depletion of p56lck during thymocyte apoptosis.   Garcia-Welsh, A; Laskin, D L; Shuler, R L; Laskin, J D P30ES005022, R01ES004738 J Leukoc Biol (1994 Oct) 7930951 Exiting the NIEHS site 1994 
Enhanced phagocytosis, chemotaxis, and production of reactive oxygen intermediates by interstitial l ...   Wizemann, T M; Laskin, D L P30ES005022, R01ES004738 Am J Respir Cell Mol Biol (1994 Sep) 8086172 Exiting the NIEHS site 1994 
Enhanced production of interleukin-1, tumor necrosis factor-alpha, and fibronectin by rat lung phago ...   Pendino, K J; Shuler, R L; Laskin, J D; Laskin, D L P30ES005022, R01ES004738 Am J Respir Cell Mol Biol (1994 Sep) 8086166 Exiting the NIEHS site 1994 
Enhanced production of nitric oxide by bone marrow cells and increased sensitivity to macrophage col ...   Punjabi, C J; Laskin, J D; Hwang, S M; MacEachern, L; Laskin, D L R01ES004738 Blood (1994 Jun 01) 8193360 Exiting the NIEHS site 1994 
Functional characterization of interstitial macrophages and subpopulations of alveolar macrophages f ...   Prokhorova, S; Lavnikova, N; Laskin, D L P30ES005022, R01ES004738 J Leukoc Biol (1994 Feb) 8301209 Exiting the NIEHS site 1994 
Osteopontin inhibits induction of nitric oxide synthase gene expression by inflammatory mediators in ...   Hwang, S M; Lopez, C A; Heck, D E; Gardner, C R; Laskin, D L; Laskin, J D; Denhardt, D T R01ES004738 J Biol Chem (1994 Jan 07) 7506262 Exiting the NIEHS site 1994 
Production of nitric oxide and peroxynitrite in the lung during acute endotoxemia.   Wizemann, T M; Gardner, C R; Laskin, J D; Quinones, S; Durham, S K; Goller, N L; Ohnishi, S T ... P30ES005022, R01ES004738 J Leukoc Biol (1994 Dec) 7527832 Exiting the NIEHS site 1994 
Production of nitric oxide by differentiated LSTRA cells is associated with expression of macrophage ...   Garcia-Welsh, A; Laskin, D L; Hwang, S M; Denhardt, D T; Laskin, J D P30ES005022, R01ES004738 J Leukoc Biol (1994 Oct) 7523558 Exiting the NIEHS site 1994 
Pulmonary and hepatic effects of inhaled ozone in rats.   Laskin, D L; Pendino, K J; Punjabi, C J; Rodriguez del Valle, M; Laskin, J D P30ES005022, R01ES004738 Environ Health Perspect (1994 Dec) 7705308 Exiting the NIEHS site 1994 
A single exogenous stimulus activates resident rat macrophages for nitric oxide production and tumor ...   Lavnikova, N; Drapier, J C; Laskin, D L R01ES004738 J Leukoc Biol (1993 Oct) 8409754 Exiting the NIEHS site 1993 
Enhanced production of nitric oxide by rat alveolar macrophages after inhalation of a pulmonary irri ...   Pendino, K J; Laskin, J D; Shuler, R L; Punjabi, C J; Laskin, D L P30ES005022, R01ES004738, T32ES007148 J Immunol (1993 Dec 15) 7505023 Exiting the NIEHS site 1993 
Induction of functionally active platelet-activating factor receptors in rat alveolar macrophages.   Pendino, K J; Gardner, C R; Laskin, J D; Laskin, D L P30ES005022, R01ES004738, T32ES007148 J Biol Chem (1993 Sep 15) 8396125 Exiting the NIEHS site 1993 
Isolation and partial characterization of subpopulations of alveolar macrophages, granulocytes, and ...   Lavnikova, N; Prokhorova, S; Helyar, L; Laskin, D L P30ES005022, R01ES004738 Am J Respir Cell Mol Biol (1993 Apr) 8476632 Exiting the NIEHS site 1993 
Platelet-activating factor-induced calcium mobilization and oxidative metabolism in hepatic macropha ...   Gardner, C R; Laskin, J D; Laskin, D L R01ES004738 J Leukoc Biol (1993 Feb) 8383168 Exiting the NIEHS site 1993 
Production of nitric oxide by murine bone marrow cells. Inverse correlation with cellular proliferat ...   Punjabi, C J; Laskin, D L; Heck, D E; Laskin, J D P30ES005022, R01ES004738 J Immunol (1992 Sep 15) 1517578 Exiting the NIEHS site 1992 
Activation of neutrophils by factors released from alveolar macrophages stimulated with collagen-lik ...   Laskin, D L; Soltys, R A; Berg, R A; Riley, D J R01ES004738 Am J Respir Cell Mol Biol (1990 May) 2160256 Exiting the NIEHS site 1990 
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