| Project Title: | WATCHING COOPERATIVE INTERACTIONS BETWEEN BASE AND NUCLEOTIDE EXCISION REPAIR PROTEINS |
|---|---|
| PI: | Van Houten, Bennett |
| Institution: | University Of Pittsburgh At Pittsburgh |
| Grant Number: | R35ES031638 |
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| BG4 antibody can recognize telomeric G-quadruplexes harboring destabilizing base modifications and l ... | Johnson, Samuel A; Paul, Tapas; Sanford, Samantha L; Schnable, Brittani L; Detwiler, Ariana C; ... | R35ES030396, R35ES031638 | Nucleic Acids Res (2024 Feb 28) |
38153143
|
2024 |
| Single-molecule analysis of purified proteins and nuclear extracts: Insights from 8-oxoguanine glyco ... | Schaich, Matthew A; Weaver, Tyler M; Roginskaya, Vera; Freudenthal, Bret D; Van Houten, Bennett | F32ES034982, R35ES031638 | DNA Repair (Amst) (2024 Feb) |
38237481
|
2024 |
| The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA. | Hengel, Sarah R; Oppenheimer, Katherine G; Smith, Chelsea M; Schaich, Matthew A; Rein, Hayley L ... | F32ES034982, R00ES033738, R01ES030335, R01ES031796, R35ES031638 | Nat Commun (2024 Aug 21) |
39169038
|
2024 |
| Thymine DNA glycosylase combines sliding, hopping, and nucleosome interactions to efficiently search ... | Schnable, Brittani L; Schaich, Matthew A; Roginskaya, Vera; Leary, Liam P; Weaver, Tyler M; Fre ... | R35ES031638 | bioRxiv (2024 Jul 27) |
37873231
|
2024 |
| Thymine DNA glycosylase combines sliding, hopping, and nucleosome interactions to efficiently search ... | Schnable, Brittani L; Schaich, Matthew A; Roginskaya, Vera; Leary, Liam P; Weaver, Tyler M; Fre ... | F32ES034982, R35ES031638 | Nat Commun (2024 Oct 25) |
39455577
|
2024 |
| DNA damage and somatic mutations in mammalian cells after irradiation with a nail polish dryer. | Zhivagui, Maria; Hoda, Areebah; Valenzuela, Noelia; Yeh, Yi-Yu; Dai, Jason; He, Yudou; Nandi, ... | R01ES030993, R01ES032547, R35ES031638 | Nat Commun (2023 Jan 17) |
36650165
|
2023 |
| Single-molecule analysis of DNA-binding proteins from nuclear extracts (SMADNE). | Schaich, Matthew A; Schnable, Brittani L; Kumar, Namrata; Roginskaya, Vera; Jakielski, Rachel C ... | R35ES031638 | Nucleic Acids Res (2023 Apr 24) |
36861323
|
2023 |
| Single-molecule analysis of purified proteins and nuclear extracts: insights from 8-oxoguanine glyco ... | Schaich, Matthew A; Weaver, Tyler M; Roginskaya, Vera; Freudenthal, Bret D; Van Houten, Bennett | R35ES031638 | bioRxiv (2023 Nov 02) |
37961208
|
2023 |
| Unlicensed origin DNA melting by MCV and SV40 polyomavirus LT proteins is independent of ATP-depende ... | Wan, Li; Toland, Sabrina; Robinson-McCarthy, Lindsey R; Lee, Nara; Schaich, Matthew A; Hengel, ... | R00ES033738, R01ES030335, R01ES031796, R35ES031638 | Proc Natl Acad Sci U S A (2023 Jul 25) |
37459531
|
2023 |
| UV irradiation remodels the specificity landscape of transcription factors. | Mielko, Zachery; Zhang, Yuning; Sahay, Harshit; Liu, Yiling; Schaich, Matthew A; Schnable, Bri ... | R35ES031638 | Proc Natl Acad Sci U S A (2023 Mar 14) |
36888663
|
2023 |
| UV-DDB as a General Sensor of DNA Damage in Chromatin: Multifaceted Approaches to Assess Its Direct ... | Raja, Sripriya J; Van Houten, Bennett | R35ES031638 | Int J Mol Sci (2023 Jun 15) |
37373320
|
2023 |
| UV-DDB stimulates the activity of SMUG1 during base excision repair of 5-hydroxymethyl-2'-deoxyuridi ... | Jang, Sunbok; Raja, Sripriya J; Roginskaya, Vera; Schaich, Matthew A; Watkins, Simon C; Van Hou ... | R35ES031638 | Nucleic Acids Res (2023 Jun 09) |
36971122
|
2023 |
| Cooperative interaction between AAG and UV-DDB in the removal of modified bases. | Jang, Sunbok; Kumar, Namrata; Schaich, Mathew A; Zhong, Zhou; van Loon, Barbara; Watkins, Simo ... | R35ES031638 | Nucleic Acids Res (2022 Dec 09) |
36511855
|
2022 |
| Global and transcription-coupled repair of 8-oxoG is initiated by nucleotide excision repair protein ... | Kumar, Namrata; Theil, Arjan F; Roginskaya, Vera; Ali, Yasmin; Calderon, Michael; Watkins, Sim ... | R35ES030396, R35ES031638 | Nat Commun (2022 Feb 21) |
35190564
|
2022 |
| Targeting Mitochondrial Function with Chemoptogenetics. | Romesberg, Amy; Van Houten, Bennett | R35ES031638 | Biomedicines (2022 Oct 01) |
36289721
|
2022 |
| Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening. | Barnes, Ryan P; de Rosa, Mariarosaria; Thosar, Sanjana A; Detwiler, Ariana C; Roginskaya, Vera; ... | R35ES030396, R35ES031638 | Nat Struct Mol Biol (2022 Jul) |
35773409
|
2022 |
| The role of UV-DDB in processing 8-oxoguanine during base excision repair. | Nagpal, Ashna; Raja, Sripriya; Van Houten, Bennett | R35ES031638 | Biochem Soc Trans (2022 Oct 31) |
36305644
|
2022 |
| Chaperones for dancing on chromatin: Role of post-translational modifications in dynamic damage dete ... | Van Houten, Bennett; Schnable, Brittani; Kumar, Namrata | R35ES031638 | Bioessays (2021 May) |
33620094
|
2021 |
| PARP1: Structural insights and pharmacological targets for inhibition. | Spiegel, Jacob O; Van Houten, Bennett; Durrant, Jacob D | R35ES031638 | DNA Repair (Amst) (2021 Jul) |
33940558
|
2021 |
| Searching for DNA Damage: Insights From Single Molecule Analysis. | Schaich, Matthew A; Van Houten, Bennett | R35ES031638 | Front Mol Biosci (2021) |
34805281
|
2021 |
| Single molecule analysis indicates stimulation of MUTYH by UV-DDB through enzyme turnover. | Jang, Sunbok; Schaich, Matthew A; Khuu, Cindy; Schnable, Brittani L; Majumdar, Chandrima; Watki ... | R35ES031638, T32ES007059 | Nucleic Acids Res (2021 Aug 20) |
34232996
|
2021 |
| The Multiple Cellular Roles of SMUG1 in Genome Maintenance and Cancer. | Raja, Sripriya; Van Houten, Bennett | R35ES031638 | Int J Mol Sci (2021 Feb 17) |
33671338
|
2021 |
| Dynamic action of DNA repair proteins as revealed by single molecule techniques: Seeing is believing ... | Kong, Muwen; Beckwitt, Emily C; Van Houten, Bennett | R35ES031638 | DNA Repair (Amst) (2020 09) |
33087275
|
2020 |
| Expanding molecular roles of UV-DDB: Shining light on genome stability and cancer. | Beecher, Maria; Kumar, Namrata; Jang, Sunbok; Rapić-Otrin, Vesna; Van Houten, Bennett | R35ES031638 | DNA Repair (Amst) (2020 10) |
32739133
|
2020 |
| The involvement of nucleotide excision repair proteins in the removal of oxidative DNA damage. | Kumar, Namrata; Raja, Sripriya; Van Houten, Bennett | R35ES031638 | Nucleic Acids Res (2020 Nov 18) |
33010169
|
2020 |