Project Title: | CHEMICAL BIOLOGY OF DNA AND RNA ALKYLATION |
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PI: | Wang, Yinsheng |
Institution: | University Of California Riverside |
Grant Number: | R35ES031707 |
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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations. | Lu, Jiuwei; Guo, Yiran; Yin, Jiekai; Chen, Jianbin; Wang, Yinsheng; Wang, Gang Greg; Song, Ji ... | R35ES031707 | Nat Commun (2024 Apr 10) | 38600075 | 2024 |
AUTS2 Controls Neuronal Lineage Choice Through a Novel PRC1-Independent Complex and BMP Inhibition. | Geng, Zhuangzhuang; Wang, Qiang; Miao, Weili; Wolf, Trevor; Chavez, Jessenia; Giddings, Emily; ... | R35ES031707 | Stem Cell Rev Rep (2023 Feb) | 36258139 | 2023 |
G-quadruplex DNA contributes to RNA polymerase II-mediated 3D chromatin architecture. | Yuan, Jun; He, Xiaomei; Wang, Yinsheng | R35ES031707 | Nucleic Acids Res (2023 Sep 08) | 37427784 | 2023 |
m1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration. | Sun, Yuxiang; Dai, Hui; Dai, Xiaoxia; Yin, Jiekai; Cui, Yuxiang; Liu, Xiaochuan; Gonzalez, Gw ... | R35ES031707 | Nature (2023 Nov) | 37938769 | 2023 |
Mass Spectrometry for Assessing Protein-Nucleic Acid Interactions. | He, Xiaomei; Chen, Xingyuan; Wang, Yinsheng | R35ES031707 | Anal Chem (2023 Jan 10) | 36625126 | 2023 |
Parallel-reaction monitoring revealed altered expression of a number of epitranscriptomic reader, wr ... | Qi, Tianyu F; Tang, Feng; Yin, Jiekai; Miao, Weili; Wang, Yinsheng | R35ES031707 | Proteomics (2023 Feb) | 35443089 | 2023 |
Phase Separation Modulates the Formation and Stabilities of DNA Guanine Quadruplex. | Gao, Zi; Yuan, Jun; He, Xiaomei; Wang, Handing; Wang, Yinsheng | R35ES031707 | JACS Au (2023 Jun 26) | 37388701 | 2023 |
Promoter R-Loops Recruit U2AF1 to Modulate Its Phase Separation and RNA Splicing. | He, Xiaomei; Yuan, Jun; Gao, Zi; Wang, Yinsheng | R35ES031707 | J Am Chem Soc (2023 Oct 04) | 37733759 | 2023 |
Proximity Proteomics Revealed Aberrant mRNA Splicing Elicited by ALS-Linked Profilin-1 Mutants. | Wei, Songbo; Yang, YenYu; Wang, Yinsheng | R35ES031707 | Anal Chem (2023 Oct 17) | 37787459 | 2023 |
Targeted Profiling of Epitranscriptomic Reader, Writer, and Eraser Proteins Regulated by H3K36me3. | Yin, Jiekai; Qi, Tianyu F; Li, Lin; Wang, Yinsheng | R35ES031707 | Anal Chem (2023 Jun 27) | 37296074 | 2023 |
Aha1 Is an Autonomous Chaperone for SULT1A1. | Liu, Xiaochuan; Wang, Yinsheng | R35ES031707 | Chem Res Toxicol (2022 Aug 15) | 35926086 | 2022 |
Amyotrophic Lateral Sclerosis-Associated Mutants of SOD1 Modulate miRNA Biogenesis through Aberrant ... | Chen, Xingyuan; He, Xiaomei; Yang, Yen-Yu; Wang, Yinsheng | R35ES031707 | ACS Chem Biol (2022 Dec 16) | 36475596 | 2022 |
Chemoproteomic Approach for the Quantitative Identification of Arsenic-Binding Proteins. | Dong, Xuejiao; Wang, Pengcheng; Wang, Yinsheng | R35ES031707 | Chem Res Toxicol (2022 Nov 21) | 36269594 | 2022 |
Facile preparation of model DNA interstrand cross-link repair intermediates using ribonucleotide-con ... | Tang, Jin; Tang, Feng; Zhao, Linlin | R35ES031707 | DNA Repair (Amst) (2022 Mar) | 35124371 | 2022 |
HSP90 and Aha1 modulate microRNA maturation through promoting the folding of Dicer1. | Liu, Xiaochuan; Yang, Yen-Yu; Wang, Yinsheng | R35ES031707 | Nucleic Acids Res (2022 Jul 08) | 35736213 | 2022 |
NT-seq: a chemical-based sequencing method for genomic methylome profiling. | Li, Xuwen; Guo, Shiyuan; Cui, Yan; Zhang, Zijian; Luo, Xinlong; Angelova, Margarita T; Landweb ... | R35ES031707 | Genome Biol (2022 May 30) | 35637459 | 2022 |
Polymerase η Recruits DHX9 Helicase to Promote Replication across Guanine Quadruplex Structures. | Tang, Feng; Wang, Yinan; Gao, Zi; Guo, Shiyuan; Wang, Yinsheng | R35ES031707 | J Am Chem Soc (2022 Aug 10) | 35905379 | 2022 |
Quantitative Assessment of Arsenite-Induced Perturbation of Ubiquitinated Proteome. | Jiang, Ji; Wang, Yinsheng | R35ES031707 | Chem Res Toxicol (2022 Sep 19) | 35994080 | 2022 |
Quantitative proteomics revealed new functions of ALKBH4. | Yu, Kailin; Qi, Tianyu F; Miao, Weili; Liu, Xiaochuan; Wang, Yinsheng | R35ES031707 | Proteomics (2022 Apr) | 34951099 | 2022 |
Structure of DNMT3B homo-oligomer reveals vulnerability to impairment by ICF mutations. | Gao, Linfeng; Guo, Yiran; Biswal, Mahamaya; Lu, Jiuwei; Yin, Jiekai; Fang, Jian; Chen, Xinyi; ... | R35ES031707 | Nat Commun (2022 Jul 22) | 35869095 | 2022 |
Targeted Profiling of Epitranscriptomic Reader, Writer, and Eraser Proteins Accompanied with Radiore ... | Qi, Tianyu F; Miao, Weili; Wang, Yinsheng | R35ES031707 | Anal Chem (2022 Jan 25) | 35021009 | 2022 |
Targeted Proteomic Analysis of Small GTPases in Radioresistant Breast Cancer Cells. | Gao, Zi; Yang, Yen-Yu; Huang, Ming; Qi, Tianyu F; Wang, Handing; Wang, Yinsheng | R35ES031707, T32ES018827 | Anal Chem (2022 Nov 01) | 36264766 | 2022 |
Targeted Quantitative Profiling of Epitranscriptomic Reader, Writer, and Eraser Proteins Using Stabl ... | Qi, Tianyu F; Liu, Xiaochuan; Tang, Feng; Yin, Jiekai; Yu, Kailin; Wang, Yinsheng | R35ES031707 | Anal Chem (2022 Sep 20) | 36084281 | 2022 |
Transcriptional Perturbations of 2,6-Diaminopurine and 2-Aminopurine. | Tan, Ying; You, Changjun; Park, Jiyeong; Kim, Hyun Suk; Guo, Su; Schärer, Orlando D; Wang, Yi ... | R35ES031707 | ACS Chem Biol (2022 Jul 15) | 35700389 | 2022 |
A Quantitative Proteomic Approach for the Identification of DNA Guanine Quadruplex-Binding Proteins. | Gao, Zi; Williams, Preston; Li, Lin; Wang, Yinsheng | R35ES031707 | J Proteome Res (2021 11 05) | 34570971 | 2021 |
Chemoproteomic Approach toward Probing the Interactomes of Perfluoroalkyl Substances. | Zhang, Quanqing; Dong, Xuejiao; Lu, Jiuwei; Song, Jikui; Wang, Yinsheng | R35ES031707 | Anal Chem (2021 Jul 13) | 34185510 | 2021 |
DNA Polymerase II Supports the Replicative Bypass of N2-Alkyl-2'-deoxyguanosine Lesions in Escherich ... | Wang, Yinan; Wu, Jun; Wu, Jiabin; Wang, Yinsheng | R35ES031707 | Chem Res Toxicol (2021 Mar 15) | 33417436 | 2021 |
DNA Polymerase η Promotes the Transcriptional Bypass of N2-Alkyl-2'-deoxyguanosine Adducts in Human ... | Tan, Ying; Guo, Su; Wu, Jun; Du, Hua; Li, Lin; You, Changjun; Wang, Yinsheng | R35ES031707 | J Am Chem Soc (2021 10 06) | 34555898 | 2021 |
DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation. | Ren, Wendan; Fan, Huitao; Grimm, Sara A; Kim, Jae Jin; Li, Linhui; Guo, Yiran; Petell, Christ ... | R35ES031707 | Nat Commun (2021 05 03) | 33941775 | 2021 |
G3BP1 binds to guanine quadruplexes in mRNAs to modulate their stabilities. | He, Xiaomei; Yuan, Jun; Wang, Yinsheng | R35ES031707 | Nucleic Acids Res (2021 11 08) | 34614161 | 2021 |
m6A-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells. | Huff, Sarah; Tiwari, Shashi Kant; Gonzalez, Gwendolyn M; Wang, Yinsheng; Rana, Tariq M | R35ES031707, T32ES018827 | ACS Chem Biol (2021 02 19) | 33412003 | 2021 |
Mitochondrial Transcription Factor A Binds to and Promotes Mutagenic Transcriptional Bypass of O4-Al ... | He, Xiaomei; Wang, Pengcheng; Wang, Yinsheng | R35ES031707 | Anal Chem (2021 Jan 19) | 33290046 | 2021 |
YY1 interacts with guanine quadruplexes to regulate DNA looping and gene expression. | Li, Lin; Williams, Preston; Ren, Wendan; Wang, Michelle Y; Gao, Zi; Miao, Weili; Huang, Ming; ... | R35ES031707, T32ES018827 | Nat Chem Biol (2021 Feb) | 33199912 | 2021 |
Arsenic Exposure and Compromised Protein Quality Control. | Tam, Lok Ming; Wang, Yinsheng | R35ES031707 | Chem Res Toxicol (2020 Jul 20) | 32410444 | 2020 |
Arsenite Binds to ZNF598 to Perturb Ribosome-Associated Protein Quality Control. | Tam, Lok Ming; Jiang, Ji; Wang, Pengcheng; Wang, Yinsheng | R35ES031707 | Chem Res Toxicol (2020 Jul 20) | 32324387 | 2020 |
Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo D ... | Gao, Linfeng; Emperle, Max; Guo, Yiran; Grimm, Sara A; Ren, Wendan; Adam, Sabrina; Uryu, Hide ... | R35ES031707 | Nat Commun (2020 07 03) | 32620778 | 2020 |
N6-methyladenine in DNA antagonizes SATB1 in early development. | Li, Zheng; Zhao, Shuai; Nelakanti, Raman V; Lin, Kaixuan; Wu, Tao P; Alderman 3rd, Myles H; Gu ... | R35ES031707 | Nature (2020 07) | 32669713 | 2020 |
Normalized retention time for scheduled liquid chromatography-multistage mass spectrometry analysis ... | Gonzalez, Gwendolyn; Cui, Yuxiang; Wang, Pengcheng; Wang, Yinsheng | R35ES031707, T32ES018827 | J Chromatogr A (2020 Jul 19) | 32505282 | 2020 |
Proteome-wide Interrogation of Small GTPases Regulated by N6-Methyladenosine Modulators. | Yang, Yen-Yu; Yu, Kailin; Li, Lin; Huang, Ming; Wang, Yinsheng | R35ES031707, T32ES018827 | Anal Chem (2020 07 21) | 32567849 | 2020 |
Structural basis for STAT2 suppression by flavivirus NS5. | Wang, Boxiao; Thurmond, Stephanie; Zhou, Kang; Sánchez-Aparicio, Maria T; Fang, Jian; Lu, Jiuw ... | R35ES031707 | Nat Struct Mol Biol (2020 10) | 32778820 | 2020 |
VEZF1-guanine quadruplex DNA interaction regulates alternative polyadenylation and detyrosinase acti ... | Li, Lin; Williams, Preston; Gao, Zi; Wang, Yinsheng | R35ES031707 | Nucleic Acids Res (2020 12 02) | 33231681 | 2020 |