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Who We Fund: Publication Detail

Project Title: CHEMICAL BIOLOGY OF DNA AND RNA ALKYLATION
PI: Wang, Yinsheng
Institution: University Of California Riverside
Grant Number: R35ES031707

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Viewing 41 publications
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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations.   Lu, Jiuwei; Guo, Yiran; Yin, Jiekai; Chen, Jianbin; Wang, Yinsheng; Wang, Gang Greg; Song, Ji ... R35ES031707 Nat Commun (2024 Apr 10) 38600075 Exiting the NIEHS site 2024 
AUTS2 Controls Neuronal Lineage Choice Through a Novel PRC1-Independent Complex and BMP Inhibition.   Geng, Zhuangzhuang; Wang, Qiang; Miao, Weili; Wolf, Trevor; Chavez, Jessenia; Giddings, Emily; ... R35ES031707 Stem Cell Rev Rep (2023 Feb) 36258139 Exiting the NIEHS site 2023 
G-quadruplex DNA contributes to RNA polymerase II-mediated 3D chromatin architecture.   Yuan, Jun; He, Xiaomei; Wang, Yinsheng R35ES031707 Nucleic Acids Res (2023 Sep 08) 37427784 Exiting the NIEHS site 2023 
m1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration.   Sun, Yuxiang; Dai, Hui; Dai, Xiaoxia; Yin, Jiekai; Cui, Yuxiang; Liu, Xiaochuan; Gonzalez, Gw ... R35ES031707 Nature (2023 Nov) 37938769 Exiting the NIEHS site 2023 
Mass Spectrometry for Assessing Protein-Nucleic Acid Interactions.   He, Xiaomei; Chen, Xingyuan; Wang, Yinsheng R35ES031707 Anal Chem (2023 Jan 10) 36625126 Exiting the NIEHS site 2023 
Parallel-reaction monitoring revealed altered expression of a number of epitranscriptomic reader, wr ...   Qi, Tianyu F; Tang, Feng; Yin, Jiekai; Miao, Weili; Wang, Yinsheng R35ES031707 Proteomics (2023 Feb) 35443089 Exiting the NIEHS site 2023 
Phase Separation Modulates the Formation and Stabilities of DNA Guanine Quadruplex.   Gao, Zi; Yuan, Jun; He, Xiaomei; Wang, Handing; Wang, Yinsheng R35ES031707 JACS Au (2023 Jun 26) 37388701 Exiting the NIEHS site 2023 
Promoter R-Loops Recruit U2AF1 to Modulate Its Phase Separation and RNA Splicing.   He, Xiaomei; Yuan, Jun; Gao, Zi; Wang, Yinsheng R35ES031707 J Am Chem Soc (2023 Oct 04) 37733759 Exiting the NIEHS site 2023 
Proximity Proteomics Revealed Aberrant mRNA Splicing Elicited by ALS-Linked Profilin-1 Mutants.   Wei, Songbo; Yang, YenYu; Wang, Yinsheng R35ES031707 Anal Chem (2023 Oct 17) 37787459 Exiting the NIEHS site 2023 
Targeted Profiling of Epitranscriptomic Reader, Writer, and Eraser Proteins Regulated by H3K36me3.   Yin, Jiekai; Qi, Tianyu F; Li, Lin; Wang, Yinsheng R35ES031707 Anal Chem (2023 Jun 27) 37296074 Exiting the NIEHS site 2023 
Aha1 Is an Autonomous Chaperone for SULT1A1.   Liu, Xiaochuan; Wang, Yinsheng R35ES031707 Chem Res Toxicol (2022 Aug 15) 35926086 Exiting the NIEHS site 2022 
Amyotrophic Lateral Sclerosis-Associated Mutants of SOD1 Modulate miRNA Biogenesis through Aberrant ...   Chen, Xingyuan; He, Xiaomei; Yang, Yen-Yu; Wang, Yinsheng R35ES031707 ACS Chem Biol (2022 Dec 16) 36475596 Exiting the NIEHS site 2022 
Chemoproteomic Approach for the Quantitative Identification of Arsenic-Binding Proteins.   Dong, Xuejiao; Wang, Pengcheng; Wang, Yinsheng R35ES031707 Chem Res Toxicol (2022 Nov 21) 36269594 Exiting the NIEHS site 2022 
Facile preparation of model DNA interstrand cross-link repair intermediates using ribonucleotide-con ...   Tang, Jin; Tang, Feng; Zhao, Linlin R35ES031707 DNA Repair (Amst) (2022 Mar) 35124371 Exiting the NIEHS site 2022 
HSP90 and Aha1 modulate microRNA maturation through promoting the folding of Dicer1.   Liu, Xiaochuan; Yang, Yen-Yu; Wang, Yinsheng R35ES031707 Nucleic Acids Res (2022 Jul 08) 35736213 Exiting the NIEHS site 2022 
NT-seq: a chemical-based sequencing method for genomic methylome profiling.   Li, Xuwen; Guo, Shiyuan; Cui, Yan; Zhang, Zijian; Luo, Xinlong; Angelova, Margarita T; Landweb ... R35ES031707 Genome Biol (2022 May 30) 35637459 Exiting the NIEHS site 2022 
Polymerase η Recruits DHX9 Helicase to Promote Replication across Guanine Quadruplex Structures.   Tang, Feng; Wang, Yinan; Gao, Zi; Guo, Shiyuan; Wang, Yinsheng R35ES031707 J Am Chem Soc (2022 Aug 10) 35905379 Exiting the NIEHS site 2022 
Quantitative Assessment of Arsenite-Induced Perturbation of Ubiquitinated Proteome.   Jiang, Ji; Wang, Yinsheng R35ES031707 Chem Res Toxicol (2022 Sep 19) 35994080 Exiting the NIEHS site 2022 
Quantitative proteomics revealed new functions of ALKBH4.   Yu, Kailin; Qi, Tianyu F; Miao, Weili; Liu, Xiaochuan; Wang, Yinsheng R35ES031707 Proteomics (2022 Apr) 34951099 Exiting the NIEHS site 2022 
Structure of DNMT3B homo-oligomer reveals vulnerability to impairment by ICF mutations.   Gao, Linfeng; Guo, Yiran; Biswal, Mahamaya; Lu, Jiuwei; Yin, Jiekai; Fang, Jian; Chen, Xinyi; ... R35ES031707 Nat Commun (2022 Jul 22) 35869095 Exiting the NIEHS site 2022 
Targeted Profiling of Epitranscriptomic Reader, Writer, and Eraser Proteins Accompanied with Radiore ...   Qi, Tianyu F; Miao, Weili; Wang, Yinsheng R35ES031707 Anal Chem (2022 Jan 25) 35021009 Exiting the NIEHS site 2022 
Targeted Proteomic Analysis of Small GTPases in Radioresistant Breast Cancer Cells.   Gao, Zi; Yang, Yen-Yu; Huang, Ming; Qi, Tianyu F; Wang, Handing; Wang, Yinsheng R35ES031707, T32ES018827 Anal Chem (2022 Nov 01) 36264766 Exiting the NIEHS site 2022 
Targeted Quantitative Profiling of Epitranscriptomic Reader, Writer, and Eraser Proteins Using Stabl ...   Qi, Tianyu F; Liu, Xiaochuan; Tang, Feng; Yin, Jiekai; Yu, Kailin; Wang, Yinsheng R35ES031707 Anal Chem (2022 Sep 20) 36084281 Exiting the NIEHS site 2022 
Transcriptional Perturbations of 2,6-Diaminopurine and 2-Aminopurine.   Tan, Ying; You, Changjun; Park, Jiyeong; Kim, Hyun Suk; Guo, Su; Schärer, Orlando D; Wang, Yi ... R35ES031707 ACS Chem Biol (2022 Jul 15) 35700389 Exiting the NIEHS site 2022 
A Quantitative Proteomic Approach for the Identification of DNA Guanine Quadruplex-Binding Proteins.   Gao, Zi; Williams, Preston; Li, Lin; Wang, Yinsheng R35ES031707 J Proteome Res (2021 11 05) 34570971 Exiting the NIEHS site 2021 
Chemoproteomic Approach toward Probing the Interactomes of Perfluoroalkyl Substances.   Zhang, Quanqing; Dong, Xuejiao; Lu, Jiuwei; Song, Jikui; Wang, Yinsheng R35ES031707 Anal Chem (2021 Jul 13) 34185510 Exiting the NIEHS site 2021 
DNA Polymerase II Supports the Replicative Bypass of N2-Alkyl-2'-deoxyguanosine Lesions in Escherich ...   Wang, Yinan; Wu, Jun; Wu, Jiabin; Wang, Yinsheng R35ES031707 Chem Res Toxicol (2021 Mar 15) 33417436 Exiting the NIEHS site 2021 
DNA Polymerase η Promotes the Transcriptional Bypass of N2-Alkyl-2'-deoxyguanosine Adducts in Human ...   Tan, Ying; Guo, Su; Wu, Jun; Du, Hua; Li, Lin; You, Changjun; Wang, Yinsheng R35ES031707 J Am Chem Soc (2021 10 06) 34555898 Exiting the NIEHS site 2021 
DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.   Ren, Wendan; Fan, Huitao; Grimm, Sara A; Kim, Jae Jin; Li, Linhui; Guo, Yiran; Petell, Christ ... R35ES031707 Nat Commun (2021 05 03) 33941775 Exiting the NIEHS site 2021 
G3BP1 binds to guanine quadruplexes in mRNAs to modulate their stabilities.   He, Xiaomei; Yuan, Jun; Wang, Yinsheng R35ES031707 Nucleic Acids Res (2021 11 08) 34614161 Exiting the NIEHS site 2021 
m6A-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells.   Huff, Sarah; Tiwari, Shashi Kant; Gonzalez, Gwendolyn M; Wang, Yinsheng; Rana, Tariq M R35ES031707, T32ES018827 ACS Chem Biol (2021 02 19) 33412003 Exiting the NIEHS site 2021 
Mitochondrial Transcription Factor A Binds to and Promotes Mutagenic Transcriptional Bypass of O4-Al ...   He, Xiaomei; Wang, Pengcheng; Wang, Yinsheng R35ES031707 Anal Chem (2021 Jan 19) 33290046 Exiting the NIEHS site 2021 
YY1 interacts with guanine quadruplexes to regulate DNA looping and gene expression.   Li, Lin; Williams, Preston; Ren, Wendan; Wang, Michelle Y; Gao, Zi; Miao, Weili; Huang, Ming; ... R35ES031707, T32ES018827 Nat Chem Biol (2021 Feb) 33199912 Exiting the NIEHS site 2021 
Arsenic Exposure and Compromised Protein Quality Control.   Tam, Lok Ming; Wang, Yinsheng R35ES031707 Chem Res Toxicol (2020 Jul 20) 32410444 Exiting the NIEHS site 2020 
Arsenite Binds to ZNF598 to Perturb Ribosome-Associated Protein Quality Control.   Tam, Lok Ming; Jiang, Ji; Wang, Pengcheng; Wang, Yinsheng R35ES031707 Chem Res Toxicol (2020 Jul 20) 32324387 Exiting the NIEHS site 2020 
Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo D ...   Gao, Linfeng; Emperle, Max; Guo, Yiran; Grimm, Sara A; Ren, Wendan; Adam, Sabrina; Uryu, Hide ... R35ES031707 Nat Commun (2020 Jul 03) 32620778 Exiting the NIEHS site 2020 
N6-methyladenine in DNA antagonizes SATB1 in early development.   Li, Zheng; Zhao, Shuai; Nelakanti, Raman V; Lin, Kaixuan; Wu, Tao P; Alderman 3rd, Myles H; Gu ... R35ES031707 Nature (2020 07) 32669713 Exiting the NIEHS site 2020 
Normalized retention time for scheduled liquid chromatography-multistage mass spectrometry analysis ...   Gonzalez, Gwendolyn; Cui, Yuxiang; Wang, Pengcheng; Wang, Yinsheng R35ES031707, T32ES018827 J Chromatogr A (2020 Jul 19) 32505282 Exiting the NIEHS site 2020 
Proteome-wide Interrogation of Small GTPases Regulated by N6-Methyladenosine Modulators.   Yang, Yen-Yu; Yu, Kailin; Li, Lin; Huang, Ming; Wang, Yinsheng R35ES031707, T32ES018827 Anal Chem (2020 07 21) 32567849 Exiting the NIEHS site 2020 
Structural basis for STAT2 suppression by flavivirus NS5.   Wang, Boxiao; Thurmond, Stephanie; Zhou, Kang; Sánchez-Aparicio, Maria T; Fang, Jian; Lu, Jiuw ... R35ES031707 Nat Struct Mol Biol (2020 10) 32778820 Exiting the NIEHS site 2020 
VEZF1-guanine quadruplex DNA interaction regulates alternative polyadenylation and detyrosinase acti ...   Li, Lin; Williams, Preston; Gao, Zi; Wang, Yinsheng R35ES031707 Nucleic Acids Res (2020 12 02) 33231681 Exiting the NIEHS site 2020 
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