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Who We Fund: Application Of Technology To Disease - Predictive Toxicology / Assay Development

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Title Principal Investigator Institution Grant Number RFA PA Number Program Officer Pubs Primary Science Code Secondary Science Code
A NONANIMAL TEST METHOD TO DETERMINE THE OCULAR SAFETY OF CONSUMER PRODUCTS AND CHEMICALS: COMMERCIALIZATION lebrun, stewart Lebrun Labs, Llc SB1ES025501 PAR20-128 Ravichandran, Lingamanaidu 2 72 - Predictive Toxicology/Assay Development -
A SEARCH FOR SAFER PLASTICS: SYNTHESIS AND REPRODUCTIVE TOXICITY EVALUATION OF NOVEL BISPHENOLS kuzmanov, aleksandra Lawrence Technological University R15ES034520 PAR21-155 Ravichandran, Lingamanaidu 0 72 - Predictive Toxicology/Assay Development 03 - Carcinogenesis/Cell Transformation
BARCODED HUMAN CELLS ENGINEERED WITH HETEROZYGOUS GENETIC DIVERSITY TO UNCOVER TOXICODYNAMIC VARIABILITY george, jay Amelia Technologies, Llc R44ES032522 ES20-008 Shaughnessy, Daniel 11 72 - Predictive Toxicology/Assay Development 03 - Carcinogenesis/Cell Transformation
COMMERCIALIZATION OF NOVEL SILICON MICROSLIT FILTERS FOR MICROPLASTIC CONTAMINATION TESTING roussie, james andrew Simpore, Inc. R44ES031036 PA20-260 Ravichandran, Lingamanaidu 1 72 - Predictive Toxicology/Assay Development 03 - Carcinogenesis/Cell Transformation
DEVELOPING AN IN VITRO TO IN VIVO PIPELINE OF MAMMARY GLAND EXPOSURE-RESPONSE RELATIONSHIPS TO PER- AND POLY-FLUOROALKYL SUBSTANCES (PFAS) oldenburg, amy l Univ Of North Carolina Chapel Hill R01ES032730 PA19-056 Ravichandran, Lingamanaidu 0 72 - Predictive Toxicology/Assay Development 03 - Carcinogenesis/Cell Transformation
DEVELOPMENT OF A RAPID SCREENING TEST FOR THE DETECTION OF DIHYDROANATOXIN-A ford, lance p Attogene R43ES034301 PA21-259 Shaughnessy, Daniel 0 72 - Predictive Toxicology/Assay Development 03 - Carcinogenesis/Cell Transformation
DEVELOPMENT OF CELL CULTURE INSERTS AND 3D IN VITRO TISSUE MODELS UTILIZING NOVEL ELECTROSPUN SCAFFOLDS hayden, patrick j Biosurfaces R44ES034681 PA22-176 Shaughnessy, Daniel 0 72 - Predictive Toxicology/Assay Development 03 - Carcinogenesis/Cell Transformation
DIVISION OF CHEMICAL TOXICOLOGY SYMPOSIA AT THE 266TH NATIONAL ACS MEETING trakselis, michael a Baylor University R13ES035636 PA21-151 Ravichandran, Lingamanaidu 2 72 - Predictive Toxicology/Assay Development 03 - Carcinogenesis/Cell Transformation
ELUCIDATING AHR SIGNALING INTERPLAY IN OROFACIAL CLEFTING AND ENDOCRINE DISRUPTION USING MICROPLATE MICROFLUIDICS johnson, brian p. Michigan State University R00ES028744 PA16-193 Shaughnessy, Daniel 2 72 - Predictive Toxicology/Assay Development -
GENE-EDITED LIVER ORGANOIDS FOR PREDICTIVE HEPATOTOXICITY joshi, pranav Bioprinting Laboratories, Inc. R43ES035653 PA22-176 Ravichandran, Lingamanaidu 3 72 - Predictive Toxicology/Assay Development 03 - Carcinogenesis/Cell Transformation
HIGH THROUGHPUT SCREEN AND HIGH INFORMATION FOLLOW-UP TESTS FOR GENOTOXICANTS dertinger, stephen d Litron Laboratories, Ltd. R44ES033138 PA20-260 Shaughnessy, Daniel 1 72 - Predictive Toxicology/Assay Development 03 - Carcinogenesis/Cell Transformation
IN VITRO TOXICITY TESTING AT MASSIVE SCALE IN DIVERSE PRIMARY HUMAN CELLS borch jensen, martin Gordian Biotechnology, Inc. R44ES032515 ES20-008 Shaughnessy, Daniel 2 72 - Predictive Toxicology/Assay Development 03 - Carcinogenesis/Cell Transformation
INVESTIGATING ENVIRONMENTAL CONTAMINANT INTERACTIONS ON THE GPCROME: AN UNEXPLORED LANDSCAPE OF ACTIVITY roman, david l. University Of Iowa R21ES036329 PA20-195 Ravichandran, Lingamanaidu 0 72 - Predictive Toxicology/Assay Development 03 - Carcinogenesis/Cell Transformation
MODELING THE RESPONSIVENESS OF SENSITIVE POPULATIONS TO GENOTOXIC AGENTS USING DNA REPAIR INHIBITORS dertinger, stephen d Litron Laboratories, Ltd. R43ES035550 ES22-006 Shaughnessy, Daniel 0 72 - Predictive Toxicology/Assay Development 03 - Carcinogenesis/Cell Transformation
MULTIFACTORIAL ENVIRONMENTAL INHIBITION OF SONIC HEDGEHOG SIGNALING: IMPACT OF CHEMICAL INTERACTIONS ON PATHWAY ACTIVITY AND CRANIOFACIAL DEVELOPMENT beames, tyler george University Of Wisconsin-Madison F31ES034632 PA21-051 Ravichandran, Lingamanaidu 0 72 - Predictive Toxicology/Assay Development 03 - Carcinogenesis/Cell Transformation
PROTECTING CHILDREN'S HEALTH BY APPLYING NOVEL APPROACHES TO ASSESS URBAN AND RURAL DRINKING WATER garcia-jaramillo, manuel Oregon State University K01ES035397 PAR21-172 Ravichandran, Lingamanaidu 0 72 - Predictive Toxicology/Assay Development 03 - Carcinogenesis/Cell Transformation
THE TOXIFIN PLATFORM: ADVANCING HIGH-THROUGHPUT SCREENING AND MECHANISTIC INSIGHTS FOR DEVELOPMENTAL NEUROTOXICANTS USING THE ZEBRAFISH MODEL preston, mary a. Nemametrix, Inc. R43ES036386 ES23-008 Ravichandran, Lingamanaidu 0 72 - Predictive Toxicology/Assay Development 03 - Carcinogenesis/Cell Transformation
TOXICOLOGICAL SCREENING IN A SINGLE ANIMAL FORMAT he, guochun Theramix, Llc R43ES034324 PA21-259 Ravichandran, Lingamanaidu 0 72 - Predictive Toxicology/Assay Development 03 - Carcinogenesis/Cell Transformation
TRIAGE OF DEVELOPMENTAL AND REPRODUCTIVE TOXICANTS USING AN IN VITRO TO IN VIVO EXTRAPOLATION (IVIVE)-TOXICOKINETIC COMPUTATIONAL MODELING APPLICATION moreau, marjory Scitovation, Llc R43ES035657 PA22-176 Ravichandran, Lingamanaidu 1 72 - Predictive Toxicology/Assay Development 03 - Carcinogenesis/Cell Transformation
VALIDATION OF THE UPAS+: A FILTER-BASED AIR SAMPLER COUPLED WITH A SUITE OF REAL-TIME SENSORS miller-lionberg, daniel d Access Sensor Technologies, Llc R44ES024041 ES20-016 Shaughnessy, Daniel 3 72 - Predictive Toxicology/Assay Development -
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