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TOX-96: Toxicity Report Tables & Curves

Pathology Tables, Survival and Growth Curves from NTP
Short-Term Studies

On 05 April 2018 indirect bilirubin measurements were added to the clinical chemistry tables. No changes were made to existing data. Pathology Working Group Approval Date: January 16, 2018.
On January 17, 2019 "Summary of Tissue Concentration (PA48)" tables were corrected: adjusted dose values are in millimolar concentrations, not molar.
On January 17, 2019, PFHSKslt Hormone Summary (R07) and Hematology Summary (PA43) date of collection was corrected to Day 28 instead of Day 28-29.
DOI: http://doi.org/10.22427/NTP-OTHER-1

TOX-96: Perfluorinated Compounds: Sulfonates

Short-Term

28-Day PFBS (Perfluorobutane sulfonate) Study Tables

E01 - Animal Removal Summary By Treatment Group (13KB)
E02 - Animals Removed from Experiment (67KB)
E03 - Growth Curves (379KB)
E04 - Mean Body Weights and Survival Table (16KB)
E05 - Clinical Observations Summary (18KB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (37KB)
P04 - Neoplasms by Individual Animal (258KB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (34KB)
P09 - Non-Neoplastic Lesions by Individual Animal (279KB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (204KB)
P11 - Statistical Analysis of Survival Data (28KB)
P14 - Individual Animal Pathology Data (295KB)
P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (259KB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (36KB)
P40 - Survival Curves (421KB)
PA06 - Organ Weights Summary (112KB)
PA41 - Clinical Chemistry Summary (259KB)
PA43 - Hematology Summary (263KB)
PA45 - Liver Special Studies Summary (31KB)
PA48 - Summary of Tissue Concentration (71KB)
R06 - Andrology Summary (50KB)
R07 - Hormone Summary (61KB)
Results of Vaginal Cytology Study Using Transition Matrix Approach (42KB)
Summary of Estrous Stages and Cycle Data (59KB)
Vaginal Cytology Plot (17KB)

28-Day PFBS (Perfluorobutane sulfonate) Individual Animal Data

Female Individual Animal Body Weight Data (18KB)
Female Individual Animal Non Neoplastic Pathology Data (52KB)
Female Individual Animal Survival Data (11KB)
Female Individual Animal Terminal Body Weight Data (19KB)
Female Individual Clinical Observations (5KB)
Male Individual Animal Body Weight Data (18KB)
Male Individual Animal Non Neoplastic Pathology Data (69KB)
Male Individual Animal Survival Data (11KB)
Male Individual Animal Terminal Body Weight Data (19KB)
Male Individual Clinical Observations (3KB)
Individual Animal Andrology Data (7KB)
Individual Animal Clinical Chemistry Data (15KB)
Individual Animal Hematology Data (17KB)
Individual Animal Hormone Data (11KB)
Individual Animal Liver Special Studies Data (6KB)
Individual Animal Organ Weight Data (13KB)
Individual Animal Tissue Concentration Data (10KB)
Individual Vaginal Cytology Data (24KB)
Individual_Animal_PCR_Data (23KB)

28-Day PFHSKslt (Perfluorohexane sulfonate potassium salt) Study Tables

E01 - Animal Removal Summary By Treatment Group (12KB)
E02 - Animals Removed from Experiment (67KB)
E03 - Growth Curves (368KB)
E04 - Mean Body Weights and Survival Table (16KB)
E05 - Clinical Observations Summary (14KB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (29KB)
P04 - Neoplasms by Individual Animal (215KB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (34KB)
P09 - Non-Neoplastic Lesions by Individual Animal (217KB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (75KB)
P11 - Statistical Analysis of Survival Data (28KB)
P14 - Individual Animal Pathology Data (276KB)
P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (216KB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (30KB)
P40 - Survival Curves (427KB)
PA06 - Organ Weights Summary Females (71KB)
PA06 - Organ Weights Summary Males (71KB)
PA41 - Clinical Chemistry Summary Females (164KB)
PA41 - Clinical Chemistry Summary Males (164KB)
PA43 - Hematology Summary Females (149KB)
PA43 - Hematology Summary Males (148KB)
PA45 - Liver Special Studies Summary (36KB)
PA48 - Summary of Tissue Concentration Males (54KB)
PA48 - Summary of Tissue Concentration Females (42KB)
R06 - Andrology Summary (50KB)
R07 - Hormone Summary Females (45KB)
R07 - Hormone Summary Males (46KB)
Results of Vaginal Cytology Study Using Transition Matrix Approach (44KB)
Summary of Estrous Stages and Cycle Data (54KB)
Vaginal Cytology Plot (17KB)

28-Day PFHSKslt (Perfluorohexane sulfonate potassium salt) Individual Animal Data

Female Individual Animal Body Weight Data (18KB)
Female Individual Animal Non Neoplastic Pathology Data (20KB)
Female Individual Animal Survival Data (11KB)
Female Individual Animal Terminal Body Weight Data (19KB)
Male Individual Animal Body Weight Data (18KB)
Male Individual Animal Non Neoplastic Pathology Data (35KB)
Male Individual Animal Survival Data (11KB)
Male Individual Animal Terminal Body Weight Data (19KB)
Male Individual Clinical Observations (2KB)
Individual Animal Andrology Data (7KB)
Individual Animal Clinical Chemistry Data Females (10KB)
Individual Animal Clinical Chemistry Data Males (11KB)
Individual Animal Hematology Data Females (12KB)
Individual Animal Hematology Data Males (12KB)
Individual Animal Hormone Data Females (8KB)
Individual Animal Hormone Data Males (8KB)
Individual Animal Liver Special Studies Data (6KB)
Individual Animal Organ Weight Data Females (9KB)
Individual Animal Organ Weight Data Males (10KB)
Individual Animal Tissue Concentration Data Females (7KB)
Individual Animal Tissue Concentration Data Males (7KB)
Individual Vaginal Cytology Data (25KB)
Individual_Animal_PCR_Data (24KB)

28-Day PFOS (Perfluorooctane Sulfonate) Study Tables

E01 - Animal Removal Summary By Treatment Group (12KB)
E02 - Animals Removed from Experiment (66KB)
E03 - Growth Curves (363KB)
E04 - Mean Body Weights and Survival Table (16KB)
E05 - Clinical Observations Summary (14KB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (34KB)
P04 - Neoplasms by Individual Animal (215KB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (34KB)
P09 - Non-Neoplastic Lesions by Individual Animal (227KB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (141KB)
P11 - Statistical Analysis of Survival Data (27KB)
P14 - Individual Animal Pathology Data (279KB)
P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (217KB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (35KB)
P40 - Survival Curves (399KB)
PA06 - Organ Weights Summary (118KB)
PA41 - Clinical Chemistry Summary (307KB)
PA43 - Hematology Summary (276KB)
PA45 - Liver Special Studies Summary (36KB)
PA48 - Summary of Tissue Concentration (73KB)
R06 - Andrology Summary (50KB)
R07 - Hormone Summary (68KB)
Results of Vaginal Cytology Study Using Transition Matrix Approach (44KB)
Summary of Estrous Stages and Cycle Data (54KB)
Vaginal Cytology Plot (17KB)

28-Day PFOS (Perfluorooctane Sulfonate) Individual Animal Data

Female Individual Animal Body Weight Data (18KB)
Female Individual Animal Non Neoplastic Pathology Data (43KB)
Female Individual Animal Survival Data (11KB)
Female Individual Animal Terminal Body Weight Data (19KB)
Male Individual Animal Body Weight Data (18KB)
Male Individual Animal Non Neoplastic Pathology Data (52KB)
Male Individual Animal Survival Data (11KB)
Male Individual Animal Terminal Body Weight Data (19KB)
Male Individual Clinical Observations (4KB)
Individual Animal Andrology Data (7KB)
Individual Animal Clinical Chemistry Data (16KB)
Individual Animal Hematology Data (18KB)
Individual Animal Hormone Data (11KB)
Individual Animal Liver Special Studies Data (6KB)
Individual Animal Organ Weight Data (15KB)
Individual Animal Tissue Concentration Data (10KB)
Individual Vaginal Cytology Data (23KB)
Individual_Animal_PCR_Data (25KB)

28-Day Wyeth 14,643 (WY) Study Tables

E01 - Animal Removal Summary By Treatment Group (12KB)
E02 - Animals Removed from Experiment (47KB)
E03 - Growth Curves (346KB)
E04 - Mean Body Weights and Survival Table (15KB)
E05 - Clinical Observations Summary (12KB)
P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (34KB)
P04 - Neoplasms by Individual Animal (165KB)
P05 - Incidence Rates of Neoplasms by Anatomic Sites (Systemic Lesions Abridged) (33KB)
P09 - Non-Neoplastic Lesions by Individual Animal (171KB)
P10 - Statistical Analysis of Non-Neoplastic Lesions (134KB)
P11 - Statistical Analysis of Survival Data (23KB)
P14 - Individual Animal Pathology Data (196KB)
P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (166KB)
P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (33KB)
P40 - Survival Curves (387KB)
PA06 - Organ Weights Summary (95KB)
PA41 - Clinical Chemistry Summary (206KB)
PA43 - Hematology Summary (185KB)
PA45 - Liver Special Studies Summary (30KB)
R06 - Andrology Summary (50KB)
R07 - Hormone Summary (50KB)
Results of Vaginal Cytology Study Using Transition Matrix Approach (43KB)
Summary of Estrous Stages and Cycle Data (54KB)
Vaginal Cytology Plot (17KB)

28-Day Wyeth 14,643 (WY) Individual Animal Data

Female Individual Animal Body Weight Data (13KB)
Female Individual Animal Non Neoplastic Pathology Data (25KB)
Female Individual Animal Survival Data (8KB)
Female Individual Animal Terminal Body Weight Data (13KB)
Male Individual Animal Body Weight Data (13KB)
Male Individual Animal Non Neoplastic Pathology Data (33KB)
Male Individual Animal Survival Data (8KB)
Male Individual Animal Terminal Body Weight Data (13KB)
Male Individual Clinical Observations (2KB)
Individual Animal Andrology Data (7KB)
Individual Animal Clinical Chemistry Data (12KB)
Individual Animal Hematology Data (14KB)
Individual Animal Hormone Data (9KB)
Individual Animal Liver Special Studies Data (5KB)
Individual Animal Organ Weight Data (12KB)
Individual Vaginal Cytology Data (24KB)
Individual_Animal_PCR_Data (20KB)