Project Title: | XENOBIOTIC RECEPTORS IN MEDIATING THE ENVIRONMENTAL EFFECTS ON HUMAN DISEASE AND MORBIDITY |
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PI: | Xie, Wen |
Institution: | University Of Pittsburgh At Pittsburgh |
Grant Number: | R35ES030429 |
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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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Estrogen sulfotransferase and sulfatase in steroid homeostasis, metabolic disease, and cancer. | Wang, Jingyuan; Feng, Ye; Liu, Brian; Xie, Wen | R35ES030429 | Steroids (2024 Jan) | 37951289 | 2024 |
Hepatocyte estrogen sulfotransferase inhibition protects female mice from concanavalin A-induced T c ... | Wang, Jingyuan; Zhang, Ziteng; Guan, Jibin; Tung, Hung-Chun; Xie, Jiaxuan; Huang, Haozhe; Chen ... | R35ES030429 | J Biol Chem (2023 Mar) | 36796516 | 2023 |
Inhibition of the SLC35B2-TPST2 Axis of Tyrosine Sulfation Attenuates the Growth and Metastasis of P ... | Cai, Xinran; Li, Sihan; Zeng, Xuemei; Xu, Meishu; Wang, Zehua; Singhi, Aatur D; Tang, Daolin; ... | R35ES030429 | Cell Mol Gastroenterol Hepatol (2023) | 37192689 | 2023 |
Sulfoconjugation of protein peptides and glycoproteins in physiology and diseases. | Xu, Pengfei; Cai, Xinran; Guan, Xiuchen; Xie, Wen | R35ES030429 | Pharmacol Ther (2023 Nov) | 37777160 | 2023 |
Xenobiotic Receptors, a Journey of Rewards. | Xie, Wen | R35ES030429 | Drug Metab Dispos (2023 Feb) | 36351836 | 2023 |
Atypical functions of xenobiotic receptors in lipid and glucose metabolism. | Wang, Jingyuan; Lu, Peipei; Xie, Wen | R35ES030429 | Med Rev (2021) (2022 Dec) | 36785576 | 2022 |
Inhibition of p53 Sulfoconjugation Prevents Oxidative Hepatotoxicity and Acute Liver Failure. | Xu, Pengfei; Xi, Yue; Wang, Pengcheng; Luka, Zigmund; Xu, Meishu; Tung, Hung-Chun; Wang, Jing ... | R35ES030429 | Gastroenterology (2022 Apr) | 34954226 | 2022 |
Intestinal Sulfation Is Essential to Protect Against Colitis and Colonic Carcinogenesis. | Xu, Pengfei; Xi, Yue; Zhu, Junjie; Zhang, Min; Luka, Zigmund; Stolz, Donna B; Cai, Xinran; Xi ... | R35ES030429 | Gastroenterology (2021 07) | 33819483 | 2021 |
The anti-fibrotic drug pirfenidone inhibits liver fibrosis by targeting the small oxidoreductase glu ... | Xi, Yue; Li, Yanping; Xu, Pengfei; Li, Sihan; Liu, Zhengsheng; Tung, Hung-Chun; Cai, Xinran; ... | R35ES030429 | Sci Adv (2021 Sep 03) | 34516906 | 2021 |
The xenobiotic receptors PXR and CAR in liver physiology, an update. | Cai, Xinran; Young, Gregory M; Xie, Wen | R35ES030429 | Biochim Biophys Acta Mol Basis Dis (2021 06 01) | 33600998 | 2021 |
ERINA Is an Estrogen-Responsive LncRNA That Drives Breast Cancer through the E2F1/RB1 Pathway. | Fang, Zihui; Wang, Yue; Wang, Zehua; Xu, Meishu; Ren, Songrong; Yang, Da; Hong, Mei; Xie, We ... | R35ES030429 | Cancer Res (2020 10 15) | 32826278 | 2020 |
Hepatic Estrogen Sulfotransferase Distantly Sensitizes Mice to Hemorrhagic Shock-Induced Acute Lung ... | Xie, Yang; Barbosa, Anne Caroline S; Xu, Meishu; Oberly, Patrick J; Ren, Songrong; Gibbs, Robe ... | R35ES030429 | Endocrinology (2020 01 01) | 31837219 | 2020 |
Long-noncoding RNAs (lncRNAs) in drug metabolism and disposition, implications in cancer chemo-resis ... | Wang, Yue; Fang, Zihui; Hong, Mei; Yang, Da; Xie, Wen | R35ES030429 | Acta Pharm Sin B (2020 Jan) | 31993309 | 2020 |
The Role of Sulfotransferases in Liver Diseases. | Xie, Yang; Xie, Wen | R35ES030429 | Drug Metab Dispos (2020 09) | 32587100 | 2020 |
Activation of Pregnane X Receptor Sensitizes Mice to Hemorrhagic Shock-Induced Liver Injury. | Xie, Yang; Xu, Meishu; Deng, Meihong; Li, Zhigang; Wang, Pengcheng; Ren, Songrong; Guo, Yan; ... | R35ES030429 | Hepatology (2019 09) | 31038762 | 2019 |
Aryl Hydrocarbon Receptor Signaling Prevents Activation of Hepatic Stellate Cells and Liver Fibrogen ... | Yan, Jiong; Tung, Hung-Chun; Li, Sihan; Niu, Yongdong; Garbacz, Wojciech G; Lu, Peipei; Bi, Y ... | R35ES030429 | Gastroenterology (2019 09) | 31170413 | 2019 |
Estrogen sulfotransferase in the metabolism of estrogenic drugs and in the pathogenesis of diseases. | Barbosa, Anne Caroline S; Feng, Ye; Yu, Chaohui; Huang, Min; Xie, Wen | R35ES030429 | Expert Opin Drug Metab Toxicol (2019 Apr) | 30822161 | 2019 |
Disease-Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of D ... | Evers, Raymond; Piquette-Miller, Micheline; Polli, Joseph W; Russel, Frans G M; Sprowl, Jason A ... | R35ES030429 | Clin Pharmacol Ther (2018 Nov) | 29756222 | 2018 |