Project Title: | MECHANISTIC ROLE OF P4501 ENZYMES IN THE PREVENTION OF PAH CARCINOGENESIS BY OMEGA 3 FATTY ACIDS |
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PI: | Moorthy, Bhagavatula |
Institution: | Baylor College Of Medicine |
Grant Number: | R01ES029382 |
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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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Attenuation of Polycyclic Aromatic Hydrocarbon (PAH)-Induced Carcinogenesis and Tumorigenesis by Ome ... | Xia, Guobin; Zhou, Guodong; Jiang, Weiwu; Chu, Chun; Wang, Lihua; Moorthy, Bhagavatula | P42ES027725, R01ES029382 | Int J Mol Sci (2024 Mar 28) | 38612589 | 2024 |
Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) augments neonatal hyperoxic lung injury ... | Stading, Rachel; Swanson, Lauren; Xia, Guobin; Jiang, Weiwu; Wang, Lihua; Couroucli, Xanthi; L ... | P42ES027725, R01ES029382 | Free Radic Biol Med (2024 Feb 01) | 38081439 | 2024 |
Aryl hydrocarbon receptor maintains hepatic mitochondrial homeostasis in mice. | Heo, Mi Jeong; Suh, Ji Ho; Lee, Sung Ho; Poulsen, Kyle L; An, Yu A; Moorthy, Bhagavatula; Hart ... | P42ES027725, R01ES029382 | Mol Metab (2023 Jun) | 37004989 | 2023 |
Loss of cytochrome P450 (CYP)1B1 mitigates hyperoxia response in adult mouse lung by reprogramming m ... | Grimm, Sandra L; Stading, Rachel E; Robertson, Matthew J; Gandhi, Tanmay; Fu, Chenlian; Jiang, ... | P30ES030285, P42ES027725, R01ES029382 | Redox Biol (2023 Aug) | 37348155 | 2023 |
Attenuation of Polycyclic Aromatic Hydrocarbon (PAH)-Mediated Pulmonary DNA Adducts and Cytochrome P ... | Zhou, Guodong; Jiang, Weiwu; Xia, Guobin; Wang, Lihua; Richardson, Molly; Chu, Chun; Moorthy, ... | P30ES030285, P42ES027725, R01ES029382 | Antioxidants (Basel) (2022 Jan 05) | 35052622 | 2022 |
The Aryl Hydrocarbon Receptor (AHR): A Novel Therapeutic Target for Pulmonary Diseases? | Shivanna, Binoy; Chu, Chun; Moorthy, Bhagavatula | P42ES027725, R01ES029382 | Int J Mol Sci (2022 Jan 28) | 35163440 | 2022 |
Effect of sex chromosomes versus hormones in neonatal lung injury. | Grimm, Sandra L; Dong, Xiaoyu; Zhang, Yuhao; Carisey, Alexandre F; Arnold, Arthur P; Moorthy, ... | P30ES030285, P42ES027725, R01ES029382 | JCI Insight (2021 07 08) | 34061778 | 2021 |
Molecular mechanisms of pulmonary carcinogenesis by polycyclic aromatic hydrocarbons (PAHs): Implica ... | Stading, Rachel; Gastelum, Grady; Chu, Chun; Jiang, Weiwu; Moorthy, Bhagavatula | P30ES030285, P42ES027725, R01ES029382 | Semin Cancer Biol (2021 11) | 34242741 | 2021 |
Role of Human NADPH Quinone Oxidoreductase (NQO1) in Oxygen-Mediated Cellular Injury and Oxidative D ... | Burke, Rebecca; Chu, Chun; Zhou, Guo-Dong; Putluri, Vasanta; Putluri, Nagireddy; Stading, Rach ... | P30ES030285, P42ES027725, R01ES029382 | Oxid Med Cell Longev (2021) | 34691356 | 2021 |
The role of cytochrome P450 (CYP) enzymes in hyperoxic lung injury. | Stading, Rachel; Couroucli, Xanthi; Lingappan, Krithika; Moorthy, Bhagavatula | P30ES030285, P42ES027725, R01ES029382 | Expert Opin Drug Metab Toxicol (2021 Feb) | 33215946 | 2021 |
Epigenetic response to hyperoxia in the neonatal lung is sexually dimorphic. | Coarfa, Cristian; Grimm, Sandra L; Katz, Tiffany; Zhang, Yuhao; Jangid, Rahul K; Walker, Chery ... | P30ES030285, P42ES027725, R01ES029382 | Redox Biol (2020 10) | 32961439 | 2020 |
Molecular role of cytochrome P4501A enzymes inoxidative stress. | Stading, Rachel; Chu, Chun; Couroucli, Xanthi; Lingappan, Krithika; Moorthy, Bhagavatula | P42ES027725, R01ES029382 | Curr Opin Toxicol (2020) | 33283080 | 2020 |
Oxygen-mediated lung injury in mice lacking the gene for NRF2: Rescue with the cytochrome P4501A-ind ... | Callaway, Danielle A; Jiang, Weiwu; Wang, Lihua; Lingappan, Krithika; Moorthy, Bhagavatula | P42ES027725, R01ES029382 | Free Radic Biol Med (2020 11 20) | 32791187 | 2020 |
Polycyclic Aromatic Hydrocarbon-induced Pulmonary Carcinogenesis in Cytochrome P450 (CYP)1A1- and 1A ... | Gastelum, Grady; Jiang, Weiwu; Wang, Lihua; Zhou, Guodong; Borkar, Roshan; Putluri, Nagireddy; ... | P42ES027725, R01ES029382 | Toxicol Sci (2020 Oct 01) | 32726451 | 2020 |
Potential role of drug metabolizing enzymes in chemotherapy-induced gastrointestinal toxicity and he ... | Tao, Gabriel; Huang, Junqing; Moorthy, Bhagavatula; Wang, Cathryn; Hu, Ming; Gao, Song; Ghose, ... | P30ES030285, P42ES027725, R01ES029382 | Expert Opin Drug Metab Toxicol (2020 Nov) | 32841068 | 2020 |
Association between elevated placental polycyclic aromatic hydrocarbons (PAHs) and PAH-DNA adducts f ... | Suter, Melissa A; Aagaard, Kjersti M; Coarfa, Cristian; Robertson, Matthew; Zhou, Guodong; Jack ... | P30ES030285, P42ES027725, R01ES029382 | Biochem Biophys Res Commun (2019 Aug 20) | 31208719 | 2019 |
Lung genotoxicity of benzo(a)pyrene in vivo involves reactivation of LINE-1 retrotransposon and earl ... | Hassanin, A A I; Tavera-Garcia, M; Moorthy, B; Zhou, G D; Ramos, K S | P30ES030285, P42ES027725, R01ES029382 | Am J Physiol Lung Cell Mol Physiol (2019 12 01) | 31596105 | 2019 |
Pilot-Scale Pyrolytic Remediation of Crude-Oil-Contaminated Soil in a Continuously-Fed Reactor: Trea ... | Song, Wen; Vidonish, Julia E; Kamath, Roopa; Yu, Pingfeng; Chu, Chun; Moorthy, Bhagavatula; Ga ... | P30ES030285, P42ES027725, R01ES029382 | Environ Sci Technol (2019 02 19) | 30681845 | 2019 |
Transcriptomic profiling identifies novel mechanisms of transcriptional regulation of the cytochrome ... | Taneja, Guncha; Maity, Suman; Jiang, Weiwu; Moorthy, Bhagavatula; Coarfa, Cristian; Ghose, Rom ... | P30ES030285, P42ES027725, R01ES029382 | Sci Rep (2019 Apr 30) | 31040347 | 2019 |