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Project Title: MECHANISTIC ROLE OF P4501 ENZYMES IN THE PREVENTION OF PAH CARCINOGENESIS BY OMEGA 3 FATTY ACIDS
PI: Moorthy, Bhagavatula
Institution: Baylor College Of Medicine
Grant Number: R01ES029382

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Viewing 19 publications
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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
Attenuation of Polycyclic Aromatic Hydrocarbon (PAH)-Induced Carcinogenesis and Tumorigenesis by Ome ...   Xia, Guobin; Zhou, Guodong; Jiang, Weiwu; Chu, Chun; Wang, Lihua; Moorthy, Bhagavatula P42ES027725, R01ES029382 Int J Mol Sci (2024 Mar 28) 38612589 Exiting the NIEHS site 2024 
Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) augments neonatal hyperoxic lung injury ...   Stading, Rachel; Swanson, Lauren; Xia, Guobin; Jiang, Weiwu; Wang, Lihua; Couroucli, Xanthi; L ... P42ES027725, R01ES029382 Free Radic Biol Med (2024 Feb 01) 38081439 Exiting the NIEHS site 2024 
Aryl hydrocarbon receptor maintains hepatic mitochondrial homeostasis in mice.   Heo, Mi Jeong; Suh, Ji Ho; Lee, Sung Ho; Poulsen, Kyle L; An, Yu A; Moorthy, Bhagavatula; Hart ... P42ES027725, R01ES029382 Mol Metab (2023 Jun) 37004989 Exiting the NIEHS site 2023 
Loss of cytochrome P450 (CYP)1B1 mitigates hyperoxia response in adult mouse lung by reprogramming m ...   Grimm, Sandra L; Stading, Rachel E; Robertson, Matthew J; Gandhi, Tanmay; Fu, Chenlian; Jiang, ... P30ES030285, P42ES027725, R01ES029382 Redox Biol (2023 Aug) 37348155 Exiting the NIEHS site 2023 
Attenuation of Polycyclic Aromatic Hydrocarbon (PAH)-Mediated Pulmonary DNA Adducts and Cytochrome P ...   Zhou, Guodong; Jiang, Weiwu; Xia, Guobin; Wang, Lihua; Richardson, Molly; Chu, Chun; Moorthy, ... P30ES030285, P42ES027725, R01ES029382 Antioxidants (Basel) (2022 Jan 05) 35052622 Exiting the NIEHS site 2022 
The Aryl Hydrocarbon Receptor (AHR): A Novel Therapeutic Target for Pulmonary Diseases?   Shivanna, Binoy; Chu, Chun; Moorthy, Bhagavatula P42ES027725, R01ES029382 Int J Mol Sci (2022 Jan 28) 35163440 Exiting the NIEHS site 2022 
Effect of sex chromosomes versus hormones in neonatal lung injury.   Grimm, Sandra L; Dong, Xiaoyu; Zhang, Yuhao; Carisey, Alexandre F; Arnold, Arthur P; Moorthy, ... P30ES030285, P42ES027725, R01ES029382 JCI Insight (2021 07 08) 34061778 Exiting the NIEHS site 2021 
Molecular mechanisms of pulmonary carcinogenesis by polycyclic aromatic hydrocarbons (PAHs): Implica ...   Stading, Rachel; Gastelum, Grady; Chu, Chun; Jiang, Weiwu; Moorthy, Bhagavatula P30ES030285, P42ES027725, R01ES029382 Semin Cancer Biol (2021 11) 34242741 Exiting the NIEHS site 2021 
Role of Human NADPH Quinone Oxidoreductase (NQO1) in Oxygen-Mediated Cellular Injury and Oxidative D ...   Burke, Rebecca; Chu, Chun; Zhou, Guo-Dong; Putluri, Vasanta; Putluri, Nagireddy; Stading, Rach ... P30ES030285, P42ES027725, R01ES029382 Oxid Med Cell Longev (2021) 34691356 Exiting the NIEHS site 2021 
The role of cytochrome P450 (CYP) enzymes in hyperoxic lung injury.   Stading, Rachel; Couroucli, Xanthi; Lingappan, Krithika; Moorthy, Bhagavatula P30ES030285, P42ES027725, R01ES029382 Expert Opin Drug Metab Toxicol (2021 Feb) 33215946 Exiting the NIEHS site 2021 
Epigenetic response to hyperoxia in the neonatal lung is sexually dimorphic.   Coarfa, Cristian; Grimm, Sandra L; Katz, Tiffany; Zhang, Yuhao; Jangid, Rahul K; Walker, Chery ... P30ES030285, P42ES027725, R01ES029382 Redox Biol (2020 10) 32961439 Exiting the NIEHS site 2020 
Molecular role of cytochrome P4501A enzymes inoxidative stress.   Stading, Rachel; Chu, Chun; Couroucli, Xanthi; Lingappan, Krithika; Moorthy, Bhagavatula P42ES027725, R01ES029382 Curr Opin Toxicol (2020) 33283080 Exiting the NIEHS site 2020 
Oxygen-mediated lung injury in mice lacking the gene for NRF2: Rescue with the cytochrome P4501A-ind ...   Callaway, Danielle A; Jiang, Weiwu; Wang, Lihua; Lingappan, Krithika; Moorthy, Bhagavatula P42ES027725, R01ES029382 Free Radic Biol Med (2020 11 20) 32791187 Exiting the NIEHS site 2020 
Polycyclic Aromatic Hydrocarbon-induced Pulmonary Carcinogenesis in Cytochrome P450 (CYP)1A1- and 1A ...   Gastelum, Grady; Jiang, Weiwu; Wang, Lihua; Zhou, Guodong; Borkar, Roshan; Putluri, Nagireddy; ... P42ES027725, R01ES029382 Toxicol Sci (2020 Oct 01) 32726451 Exiting the NIEHS site 2020 
Potential role of drug metabolizing enzymes in chemotherapy-induced gastrointestinal toxicity and he ...   Tao, Gabriel; Huang, Junqing; Moorthy, Bhagavatula; Wang, Cathryn; Hu, Ming; Gao, Song; Ghose, ... P30ES030285, P42ES027725, R01ES029382 Expert Opin Drug Metab Toxicol (2020 Nov) 32841068 Exiting the NIEHS site 2020 
Association between elevated placental polycyclic aromatic hydrocarbons (PAHs) and PAH-DNA adducts f ...   Suter, Melissa A; Aagaard, Kjersti M; Coarfa, Cristian; Robertson, Matthew; Zhou, Guodong; Jack ... P30ES030285, P42ES027725, R01ES029382 Biochem Biophys Res Commun (2019 Aug 20) 31208719 Exiting the NIEHS site 2019 
Lung genotoxicity of benzo(a)pyrene in vivo involves reactivation of LINE-1 retrotransposon and earl ...   Hassanin, A A I; Tavera-Garcia, M; Moorthy, B; Zhou, G D; Ramos, K S P30ES030285, P42ES027725, R01ES029382 Am J Physiol Lung Cell Mol Physiol (2019 12 01) 31596105 Exiting the NIEHS site 2019 
Pilot-Scale Pyrolytic Remediation of Crude-Oil-Contaminated Soil in a Continuously-Fed Reactor: Trea ...   Song, Wen; Vidonish, Julia E; Kamath, Roopa; Yu, Pingfeng; Chu, Chun; Moorthy, Bhagavatula; Ga ... P30ES030285, P42ES027725, R01ES029382 Environ Sci Technol (2019 02 19) 30681845 Exiting the NIEHS site 2019 
Transcriptomic profiling identifies novel mechanisms of transcriptional regulation of the cytochrome ...   Taneja, Guncha; Maity, Suman; Jiang, Weiwu; Moorthy, Bhagavatula; Coarfa, Cristian; Ghose, Rom ... P30ES030285, P42ES027725, R01ES029382 Sci Rep (2019 Apr 30) 31040347 Exiting the NIEHS site 2019 
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Last Reviewed: December 05, 2024