| Project Title: | CYP2B6 INHIBITORS PERTURB PROPER DISTRIBUTION OF LIPIDS LEADING TO OBESITY AND FATTY LIVER DISEASE |
|---|---|
| PI: | Baldwin, William S |
| Institution: | Clemson University |
| Grant Number: | R15ES017321 |
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Viewing 36 publications
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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| Age- and Diet-Dependent Changes in Hepatic Lipidomic Profiles of Phospholipids in Male Mice: Age Acc ... | Heintz, Melissa M; Kumar, Ramiya; Maner-Smith, Kristal M; Ortlund, Eric A; Baldwin, William S | R15ES017321 | J Lipids (2022) |
35391786
|
2022 |
| Dataset of endo- and xenobiotic inhibition of CYP2B6: Comparison to CYP3A4. | Olack, Emily M; Heintz, Melissa M; Baldwin, William S | R15ES017321 | Data Brief (2022 Apr) |
35282180
|
2022 |
| The reproductive effects of the cancer chemotherapy agent, Carmofur, on Daphnia magna are mediated b ... | Gessner, Emily E; Shah, Manav H; Ghent, Bricen N; Westbrook, Nathaniel E; van den Hurk, Peter; ... | R15ES017321 | Ecotoxicology (2022 Jul) |
35579761
|
2022 |
| Increased toxicity and retention of perflourooctane sulfonate (PFOS) in humanized CYP2B6-Transgenic ... | Hamilton, Matthew C; Heintz, Melissa M; Pfohl, Marisa; Marques, Emily; Ford, Lucie; Slitt, Ang ... | P42ES027706, R15ES017321 | Food Chem Toxicol (2021 Jun) |
33838175
|
2021 |
| 20th Pollutant Responses in Marine Organisms (PRIMO 20): Global issues and fundamental mechanisms ca ... | Baldwin, William S; Bain, Lisa J; Di Giulio, Richard; Kullman, Seth; Rice, Charles D; Ringwood, ... | R15ES017321 | Aquat Toxicol (2020 Oct) |
32932042
|
2020 |
| Gender differences in diet-induced steatotic disease in Cyp2b-null mice. | Heintz, Melissa M; McRee, Rebecca; Kumar, Ramiya; Baldwin, William S | R15ES017321 | PLoS One (2020) |
32155178
|
2020 |
| Chemical Activation of the Constitutive Androstane Receptor Leads to Activation of Oxidant-Induced N ... | Rooney, John P; Oshida, Keiyu; Kumar, Ramiya; Baldwin, William S; Corton, J Christopher | R15ES017321 | Toxicol Sci (2019 01 01) |
30203046
|
2019 |
| Cyp2b-null male mice are susceptible to diet-induced obesity and perturbations in lipid homeostasis. | Heintz, Melissa M; Kumar, Ramiya; Rutledge, Meredith M; Baldwin, William S | R15ES017321 | J Nutr Biochem (2019 08) |
31202118
|
2019 |
| Phase 0 of the Xenobiotic Response: Nuclear Receptors and Other Transcription Factors as a First Ste ... | Baldwin, William S | R15ES017321 | Nucl Receptor Res (2019) |
31815118
|
2019 |
| Cyp2b-Knockdown Mice Poorly Metabolize Corn Oil and Are Age-Dependent Obese. | Damiri, Basma; Baldwin, William S | R15ES017321 | Lipids (2018 09) |
30421529
|
2018 |
| High fat diet induced obesity is mitigated in Cyp3a-null female mice. | Kumar, Ramiya; Litoff, Elizabeth J; Boswell, W Tyler; Baldwin, William S | R15ES017321 | Chem Biol Interact (2018 Jun 01) |
29738703
|
2018 |
| Non-Mammalian Nuclear Receptors: From Evolution to Human Disease. | Gissendanner, Chris R; Baldwin, William S; Schaaf, Marcel J M | R15ES017321 | Nucl Receptor Res (2018) |
30221173
|
2018 |
| Annotation of the Nuclear Receptors in an Estuarine Fish species, Fundulus heteroclitus. | Baldwin, William S; Boswell, W Tyler; Ginjupalli, Gautam; Litoff, Elizabeth J | R15ES017321 | Nucl Receptor Res (2017) |
28804711
|
2017 |
| Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-n ... | Kumar, Ramiya; Mota, Linda C; Litoff, Elizabeth J; Rooney, John P; Boswell, W Tyler; Courter, ... | R15ES017321 | PLoS One (2017) |
28350814
|
2017 |
| Exchange of polar lipids from adults to neonates in Daphnia magna: Perturbations in sphingomyelin al ... | Sengupta, Namrata; Reardon, Delaney C; Gerard, Patrick D; Baldwin, William S | R15ES017321 | PLoS One (2017) |
28542405
|
2017 |
| RNA sequencing indicates that atrazine induces multiple detoxification genes in Daphnia magna and th ... | Schmidt, Allison M; Sengupta, Namrata; Saski, Christopher A; Noorai, Rooksana E; Baldwin, Willi ... | R15ES017321 | Chemosphere (2017 Dec) |
28968576
|
2017 |
| Perturbations in polar lipids, starvation survival and reproduction following exposure to unsaturate ... | Sengupta, Namrata; Gerard, Patrick D; Baldwin, William S | R15ES017321 | Chemosphere (2016 Feb) |
26606184
|
2016 |
| Arachidonic acid enhances reproduction in Daphnia magna and mitigates changes in sex ratios induced ... | Ginjupalli, Gautam K; Gerard, Patrick D; Baldwin, William S | R15ES017321 | Environ Toxicol Chem (2015 Mar) |
25393616
|
2015 |
| Repression of multiple CYP2D genes in mouse primary hepatocytes with a single siRNA construct. | Elraghy, Omaima; Baldwin, William S | R15ES017321 | In Vitro Cell Dev Biol Anim (2015 Jan) |
25124873
|
2015 |
| The HR96 activator, atrazine, reduces sensitivity of D. magna to triclosan and DHA. | Sengupta, Namrata; Litoff, Elizabeth J; Baldwin, William S | R15ES017321 | Chemosphere (2015 Jun) |
25747156
|
2015 |
| Annotation of the Daphnia magna nuclear receptors: comparison to Daphnia pulex. | Litoff, Elizabeth J; Garriott, Travis E; Ginjupalli, Gautam K; Butler, LaToya; Gay, Claudy; Sco ... | R15ES017321 | Gene (2014 Nov 15) |
25239664
|
2014 |
| The HR97 (NR1L) group of nuclear receptors: a new group of nuclear receptors discovered in Daphnia s ... | Li, Yangchun; Ginjupalli, Gautam K; Baldwin, William S | R15ES017321 | Gen Comp Endocrinol (2014 Sep 15) |
25092536
|
2014 |
| The time- and age-dependent effects of the juvenile hormone analog pesticide, pyriproxyfen on Daphni ... | Ginjupalli, Gautam K; Baldwin, William S | R15ES017321 | Chemosphere (2013 Aug) |
23714148
|
2013 |
| Daphnia HR96 is a promiscuous xenobiotic and endobiotic nuclear receptor. | Karimullina, Elina; Li, Yangchun; Ginjupalli, Gautam K; Baldwin, William S | R15ES017321 | Aquat Toxicol (2012 Jul 15) |
22466357
|
2012 |
| Lentiviral-mediated RNAi knockdown yields a novel mouse model for studying Cyp2b function. | Damiri, Basma; Holle, Eric; Yu, Xianzhong; Baldwin, William S | R15ES017321 | Toxicol Sci (2012 Feb) |
22083726
|
2012 |
| Nonylphenol-mediated CYP induction is PXR-dependent: The use of humanized mice and human hepatocytes ... | Mota, Linda C; Barfield, Christina; Hernandez, Juan P; Baldwin, William S | R15ES017321 | Toxicol Appl Pharmacol (2011 May 1) |
21376070
|
2011 |
| Selective imaging and killing of cancer cells with protein-activated near-infrared fluorescing nanop ... | Rungta, Parul; Bandera, Yuriy P; Roeder, Ryan D; Li, Yangchun; Baldwin, William S; Sharma, Dee ... | R15ES017321 | Macromol Biosci (2011 Jul 07) |
21480531
|
2011 |
| Constitutive androstane receptor -null mice are sensitive to the toxic effects of parathion: associa ... | Mota, Linda C; Hernandez, Juan P; Baldwin, William S | R15ES017321 | Drug Metab Dispos (2010 Sep) |
20573718
|
2010 |
| Dose-responsive gene expression changes in juvenile and adult mummichogs (Fundulus heteroclitus) aft ... | Gonzalez, Horacio O; Hu, Jianjun; Gaworecki, Kristen M; Roling, Jonathan A; Baldwin, William S; ... | R15ES017321 | Mar Environ Res (2010 Aug) |
20451245
|
2010 |
| Integrating omic technologies into aquatic ecological risk assessment and environmental monitoring: ... | Van Aggelen, Graham; Ankley, Gerald T; Baldwin, William S; Bearden, Daniel W; Benson, William H ... | R15ES017321 | Environ Health Perspect (2010 Jan) |
20056575
|
2010 |
| Interactions of the crustacean nuclear receptors HR3 and E75 in the regulation of gene transcription ... | Hannas, Bethany R; Wang, Ying H; Baldwin, William S; Li, Yangchun; Wallace, Andrew D; LeBlanc, ... | R15ES017321, T32ES007046 | Gen Comp Endocrinol (2010 Jun 1) |
20346363
|
2010 |
| A concentration addition model for the activation of the constitutive androstane receptor by xenobio ... | Baldwin, William S; Roling, Jonathan A | R15ES017321 | Toxicol Sci (2009 Jan) |
18832183
|
2009 |
| Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolis ... | Hernandez, J P; Mota, L C; Baldwin, W S | R15ES017321 | Curr Pharmacogenomics Person Med (2009 Jun 01) |
20871735
|
2009 |
| Annotation, phylogenetics, and expression of the nuclear receptors in Daphnia pulex. | Thomson, Susanne A; Baldwin, William S; Wang, Ying H; Kwon, Gwijun; Leblanc, Gerald A | R15ES017321 | BMC Genomics (2009 Oct 28) |
19863811
|
2009 |
| Sexually dimorphic regulation and induction of P450s by the constitutive androstane receptor (CAR). | Hernandez, J P; Mota, L C; Huang, W; Moore, D D; Baldwin, W S | R15ES017321 | Toxicology (2009 Feb 4) |
19041682
|
2009 |
| The cytochrome P450 (CYP) gene superfamily in Daphnia pulex. | Baldwin, William S; Marko, Peter B; Nelson, David R | R15ES017321 | BMC Genomics (2009 Apr 21) |
19383150
|
2009 |