These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.
Viewing 226 publications
Export to Excel
(http://www.niehs.nih.gov//portfolio/index.cfm?do=portfolio.sciencecodepubs&&sc=07&topic=7&format=excel)
| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| Incorporating new approach methods (NAMs) data in dose-response assessments: The future is now! | Lu, En-Hsuan; Rusyn, Ivan; Chiu, Weihsueh A | P30ES029067, P42ES027704, R01ES029911 | J Toxicol Environ Health B Crit Rev (2025 Jan 02) |
39390665
|
2025 |
| A comprehensive analysis of clinical and polygenic germline influences on somatic mutational burden. | Taraszka, Kodi; Groha, Stefan; King, David; Tell, Robert; White, Kevin; Ziv, Elad; Zaitlen, N ... | R01ES029929 | Am J Hum Genet (2024 Feb 01) |
38211585
|
2024 |
| A powerful approach to identify replicable variants in genome-wide association studies. | Li, Yan; Lei, Haochen; Wen, Xiaoquan; Cao, Hongyuan | R01ES033634 | Am J Hum Genet (2024 May 02) |
38701746
|
2024 |
| A preclinical model of severe NASH-like liver injury by chronic administration of a high-fat and hig ... | Willett, Rose A; Tryndyak, Volodymyr P; Hughes Hanks, Jennifer M; Elkins, Lana; Nagumalli, Sure ... | R01ES029911 | Toxicol Appl Pharmacol (2024 Oct) |
39084266
|
2024 |
| An integrative multi-context Mendelian randomization method for identifying risk genes across human ... | Lu, Yihao; Xu, Ke; Maydanchik, Nathaniel; Kang, Bowei; Pierce, Brandon L; Yang, Fan; Chen, Li ... | R35ES028379 | Am J Hum Genet (2024 Aug 08) |
39053459
|
2024 |
| BMI Interacts with the Genome to Regulate Gene Expression Globally, with Emphasis in the Brain and G ... | Signer, Rebecca; Seah, Carina; Young, Hannah; Retallick-Townsley, Kayla; De Pins, Agathe; Cote, ... | R01ES033630 | medRxiv (2024 Nov 28) |
39649609
|
2024 |
| Characterization of caffeine response regulatory variants in vascular endothelial cells. | Boye, Carly; Kalita, Cynthia A; Findley, Anthony S; Alazizi, Adnan; Wei, Julong; Wen, Xiaoquan ... | R01ES033634 | Elife (2024 Feb 09) |
38334359
|
2024 |
| Chronic Overlapping Pain Conditions and Nociplastic Pain. | Johnston, Keira J A; Signer, Rebecca; Huckins, Laura M | R01ES033630 | medRxiv (2024 May 08) |
38766033
|
2024 |
| Circulating Exosomal miRNA Profiles in Non-Small Cell Lung Cancers. | Hassanin, Abeer A I; Ramos, Kenneth S | R01ES034542 | Cells (2024 Sep 17) |
39329746
|
2024 |
| Crosstalk of MAP3K1 and EGFR signaling mediates gene-environment interactions that block development ... | Wang, Jingjing; Xiao, Bo; Kimura, Eiki; Mongan, Maureen; Hsu, Wei-Wen; Medvedovic, Mario; Puga ... | P30ES006096, R21ES033342 | J Biol Chem (2024 Jul) |
38897570
|
2024 |
| Decoding the transcriptomic signatures of psychological trauma in human cortex and amygdala. | Hicks, Emily M; Seah, Carina; Deans, Michael; Lee, Seoyeon; Johnston, Keira J A; Cote, Alanna; ... | R01ES033630 | bioRxiv (2024 Oct 23) |
39484441
|
2024 |
| Deep autoencoder-based behavioral pattern recognition outperforms standard statistical methods in hi ... | Green, Adrian J; Truong, Lisa; Thunga, Preethi; Leong, Connor; Hancock, Melody; Tanguay, Robyn ... | P30ES025128, P30ES030287, R01ES033243 | PLoS Comput Biol (2024 Sep) |
39255309
|
2024 |
| DNA methylation correlates of chronological age in diverse human tissue types. | Jain, Niyati; Li, James L; Tong, Lin; Jasmine, Farzana; Kibriya, Muhammad G; Demanelis, Kathry ... | R35ES028379 | Epigenetics Chromatin (2024 Aug 08) |
39118140
|
2024 |
| Dynamic convergence of autism disorder risk genes across neurodevelopment. | Garcia, Meilin Fernandez; Retallick-Townsley, Kayla; Pruitt, April; Davidson, Elizabeth; Dai, Y ... | R01ES033630 | bioRxiv (2024 Aug 24) |
39229156
|
2024 |
| Dynamic stress- and inflammatory-based regulation of psychiatric risk loci in human neurons. | Retallick-Townsley, Kayla G; Lee, Seoyeon; Cartwright, Sam; Cohen, Sophie; Sen, Annabel; Jia, ... | R01ES033630 | bioRxiv (2024 Jul 09) |
39026810
|
2024 |
| Eating disorders: are gut microbiota to blame? | Xu, Jiayi; Carroll, Ian M; Huckins, Laura M | R01ES033630 | Trends Mol Med (2024 Apr) |
38040602
|
2024 |
| Embryonic origin of two ASD subtypes of social symptom severity: the larger the brain cortical organ ... | Courchesne, Eric; Taluja, Vani; Nazari, Sanaz; Aamodt, Caitlin M; Pierce, Karen; Duan, Kuaikua ... | R01ES033636 | Mol Autism (2024 May 25) |
38790065
|
2024 |
| Environmental radiation exposure at Chornobyl has not systematically affected the genomes or chemica ... | Tintori, Sophia C; Çağlar, Derin; Ortiz, Patrick; Chyzhevskyi, Ihor; Mousseau, Timothy A; Rockm ... | R01ES029930 | Proc Natl Acad Sci U S A (2024 Mar 12) |
38442158
|
2024 |
| FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in ... | Kodavati, Manohar; Wang, Haibo; Guo, Wenting; Mitra, Joy; Hegde, Pavana M; Provasek, Vincent; ... | R01ES012512 | Nat Commun (2024 Mar 09) |
38461154
|
2024 |
| Generation of 'semi-guided' cortical organoids with complex neural oscillations. | Fitzgerald, Michael Q; Chu, Tiffany; Puppo, Francesca; Blanch, Rebeca; Chillón, Miguel; Subrama ... | R01ES033636 | Nat Protoc (2024 Sep) |
38702386
|
2024 |
| Genetically Regulated Gene Expression in the Brain Associated With Chronic Pain: Relationships With ... | Johnston, Keira J A; Cote, Alanna C; Hicks, Emily; Johnson, Jessica; Huckins, Laura M | R01ES033630 | Biol Psychiatry (2024 Apr 15) |
37678542
|
2024 |
| Genomic insights into the comorbidity between type 2 diabetes and schizophrenia. | Arruda, Ana Luiza; Khandaker, Golam M; Morris, Andrew P; Smith, George Davey; Huckins, Laura M; ... | R01ES033630 | Schizophrenia (Heidelb) (2024 Feb 21) |
38383672
|
2024 |
| Genotype × environment interactions in gene regulation and complex traits. | Boye, Carly; Nirmalan, Shreya; Ranjbaran, Ali; Luca, Francesca | R01ES033634 | Nat Genet (2024 Jun) |
38858456
|
2024 |
| Global screening of base excision repair in nucleosome core particles. | Sutton, Treshaun B; Sawyer, Danielle L; Naila, Tasmin; Sweasy, Joann B; Tomkinson, Alan E; Dela ... | R01ES012512 | DNA Repair (Amst) (2024 Dec) |
39476546
|
2024 |
| Hypothalamic sex-specific metabolic shift by canagliflozin during aging. | Jayarathne, Hashan S M; Sullivan, Ryan; Stilgenbauer, Lukas; Debarba, Lucas K; Kuchumov, Artur; ... | P42ES030991, R01ES033171, R01ES033171, R01ES034410, R56ES034765 | Geroscience (2024 Oct) |
38801647
|
2024 |
| Independently evolved pollution resistance in four killifish populations is largely explained by few ... | Miller, Jeffrey T; Clark, Bryan W; Reid, Noah M; Karchner, Sibel I; Roach, Jennifer L; Hahn, M ... | R01ES032323, R01ES033888, R01ES033888, T32ES007059 | Evol Appl (2024 Jan) |
38293268
|
2024 |
| Long Interspersed Nuclear Element-1 Analytes in Extracellular Vesicles as Tools for Molecular Diagno ... | Bowers, Emma C; Cavalcante, Alexandre M; Nguyen, Kimberly; Li, Can; Wang, Yingshan; El-Zein, R ... | R01ES034542 | Int J Mol Sci (2024 Jan 18) |
38256242
|
2024 |
| Loss of GTF2I promotes neuronal apoptosis and synaptic reduction in human cellular models of neurode ... | Adams, Jason W; Vinokur, Annabelle; de Souza, Janaína S; Austria, Charles; Guerra, Bruno S; Her ... | R01ES033636 | Cell Rep (2024 Mar 26) |
38416640
|
2024 |
| Mammalian DNA ligases; roles in maintaining genome integrity. | Sallmyr, Annahita; Bhandari, Seema Khattri; Naila, Tasmin; Tomkinson, Alan E | R01ES012512 | J Mol Biol (2024 Jan 01) |
37714297
|
2024 |
| MAP3K1 regulates female reproductive tract development. | Kimura, Eiki; Mongan, Maureen; Xiao, Bo; Christianto, Antonius; Wang, Jingjing; Carreira, Vini ... | P30ES006096, R21ES033342 | Dis Model Mech (2024 Mar 01) |
38501211
|
2024 |
| Metabolomic Effects of Folic Acid Supplementation in Adults: Evidence from the FACT Trial. | Martinez-Morata, Irene; Wu, Haotian; Galvez-Fernandez, Marta; Ilievski, Vesna; Bottiglieri, Teo ... | R01ES030945, R01ES030945, R35ES028379 | J Nutr (2024 Feb) |
38092151
|
2024 |
| Modulation of the Oncogenic LINE-1 Regulatory Network in Non-Small Cell Lung Cancer by Exosomal miRN ... | Hassanin, Abeer A I; Ramos, Kenneth S | R01ES034542 | Int J Mol Sci (2024 Oct 03) |
39409003
|
2024 |
| Open Science Practices in Psychiatric Genetics: A Primer. | Kępińska, Adrianna P; Johnson, Jessica S; Huckins, Laura M | R01ES033630 | Biol Psychiatry Glob Open Sci (2024 Jan) |
38298792
|
2024 |
| Oral Contraceptives and the Risk of Psychiatric Side Effects: A Review. | Ciarcia, Julia; Huckins, Laura M | R01ES033630 | Complex Psychiatry (2024) |
39148498
|
2024 |
| Reassessing the modularity of gene co-expression networks using the Stochastic Block Model. | Melo, Diogo; Pallares, Luisa F; Ayroles, Julien F | R01ES029929 | PLoS Comput Biol (2024 Jul) |
39074140
|
2024 |
| Reassessing the modularity of gene co-expression networks using the Stochastic Block Model. | Melo, Diogo; Pallares, Luisa F; Ayroles, Julien F | R01ES029929 | bioRxiv (2024 Apr 10) |
37398186
|
2024 |
| Redundant but essential functions of PARP1 and PARP2 in DNA ligase I-independent DNA replication. | Bhandari, Seema Khattri; Wiest, Nathaniel; Sallmyr, Annahita; Du, Ruofei; Tomkinson, Alan E | R01ES012512 | Nucleic Acids Res (2024 Sep 23) |
39106163
|
2024 |
| Returning personal genetic information on susceptibility to arsenic toxicity to research participant ... | Tamayo, Lizeth I; Haque, Syed Emdadul; Islam, Tariqul; Ahmed, Alauddin; Rahman, Moziber; Horayr ... | P30ES027792, R35ES028379 | Environ Res (2024 Jan 01) |
37879393
|
2024 |
| Single-nucleus RNA sequencing of human periventricular white matter in vascular dementia. | Díaz-Pérez, Sebastián; DeLong, Jonathan H; Rivier, Cyprien A; Lee, Chia-Yi; Askenase, Michael H ... | R01ES033630 | bioRxiv (2024 Dec 10) |
39713290
|
2024 |
| Structure-specific variation in per- and polyfluoroalkyl substances toxicity among genetically diver ... | Leuthner, Tess C; Zhang, Sharon; Kohrn, Brendan F; Stapleton, Heather M; Baugh, L Ryan | F32ES034954, P42ES010356, R01ES029930 | bioRxiv (2024 Jun 02) |
38854041
|
2024 |
| Targeting Fatty Acid Desaturase I Inhibits Renal Cancer Growth Via ATF3-mediated ER Stress Response. | Heravi, Gioia; Liu, Zhenjie; Herroon, Mackenzie; Wilson, Alexis; Fan, Yang-Yi; Jiang, Yang; Va ... | R01ES034410 | bioRxiv (2024 Mar 27) |
38586033
|
2024 |
| The association of cigarette smoking with DNA methylation and gene expression in human tissue sample ... | Li, James L; Jain, Niyati; Tamayo, Lizeth I; Tong, Lin; Jasmine, Farzana; Kibriya, Muhammad G; ... | R35ES028379 | Am J Hum Genet (2024 Apr 04) |
38490207
|
2024 |
| The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology. | Linnerbauer, Mathias; Lößlein, Lena; Vandrey, Oliver; Peter, Anne; Han, Yanan; Tsaktanis, Than ... | R01ES025530, R01ES032323 | Nat Immunol (2024 Mar) |
38409259
|
2024 |
| The impact of chronic pain on brain gene expression. | Collier, Lily; Seah, Carina; Hicks, Emily M; Traumatic Stress Brain Research Group; Holtzheimer, ... | R01ES033630 | medRxiv (2024 May 21) |
38826319
|
2024 |
| The Impact of Inherited Genetic Variation on DNA Methylation in Prostate Cancer and Benign Tissues o ... | Delgado, Dayana; Gillard, Marc; Tong, Lin; Demanelis, Kathryn; Oliva, Meritxell; Gleason, Kevi ... | R35ES028379 | Cancer Epidemiol Biomarkers Prev (2024 Apr 03) |
38294689
|
2024 |
| Time-course characterization of whole-transcriptome dynamics of HepG2/C3A spheroids and its toxicolo ... | Kim, Chanhee; Zhu, Zhaohan; Barbazuk, W Brad; Bacher, Rhonda L; Vulpe, Christopher D | R01ES033625 | Toxicol Lett (2024 Nov) |
39368564
|
2024 |
| Unraveling the genetics of arsenic toxicity with cellular morphology QTL. | O'Connor, Callan; Keele, Gregory R; Martin, Whitney; Stodola, Timothy; Gatti, Daniel; Hoffman, ... | R01ES029916 | PLoS Genet (2024 Apr) |
38662777
|
2024 |
| WHAMM functions in kidney reabsorption and polymerizes actin to promote autophagosomal membrane clos ... | Coulter, Alyssa M; Cortés, Valerie; Theodore, Corey J; Cianciolo, Rachel E; Korstanje, Ron; Cam ... | R01ES029916 | Mol Biol Cell (2024 Jun 01) |
38598293
|
2024 |
| WHAMM functions in kidney reabsorption and polymerizes actin to promote autophagosomal membrane clos ... | Coulter, Alyssa M; Cortés, Valerie; Theodore, Corey J; Cianciolo, Rachel E; Korstanje, Ron; Cam ... | R01ES029916 | bioRxiv (2024 Jan 23) |
38328079
|
2024 |
| A nonparametric alternative to the Cochran-Armitage trend test in genetic case-control association s ... | Manning, Sydney E; Ku, Hung-Chih; Dluzen, Douglas F; Xing, Chao; Zhou, Zhengyang | R03ES034138 | PLoS One (2023) |
36730335
|
2023 |
| A Varying Coefficient Model to Jointly Test Genetic and Gene-Environment Interaction Effects. | Zhou, Zhengyang; Ku, Hung-Chih; Manning, Sydney E; Zhang, Ming; Xing, Chao | R03ES034138 | Behav Genet (2023 Jul) |
36622576
|
2023 |
| Adaptations to water stress and pastoralism in the Turkana of northwest Kenya. | Lea, A J; Caldas, I V; Garske, K M; Echwa, J; Gurven, M; Handley, C; Kahumbu, J; Kamau; Kinyu ... | F32ES034668 | bioRxiv (2023 Jan 19) |
36711473
|
2023 |
| Applying an evolutionary mismatch framework to understand disease susceptibility. | Lea, Amanda J; Clark, Andrew G; Dahl, Andrew W; Devinsky, Orrin; Garcia, Angela R; Golden, Chr ... | R01ES029929 | PLoS Biol (2023 Sep) |
37695771
|
2023 |
| Better together: Non-additive interactions between schizophrenia risk genes. | Deans, P J Michael; Brennand, Kristen J | R01ES033630 | Cell Genom (2023 Sep 13) |
37719145
|
2023 |
| Capturing continuous, long timescale behavioral changes in Drosophila melanogaster postural data. | McKenzie-Smith, Grace C; Wolf, Scott W; Ayroles, Julien F; Shaevitz, Joshua W | R01ES029929 | ArXiv (2023 Sep 07) |
37731659
|
2023 |
| Cell morphology QTL reveal gene by environment interactions in a genetically diverse cell population ... | O'Connor, Callan; Keele, Gregory R; Martin, Whitney; Stodola, Timothy; Gatti, Daniel; Hoffman, ... | R01ES029916 | bioRxiv (2023 Nov 18) |
38014303
|
2023 |
| Characterizing the landscape of gene expression variance in humans. | Wolf, Scott; Melo, Diogo; Garske, Kristina M; Pallares, Luisa F; Lea, Amanda J; Ayroles, Julie ... | F32ES034668, R01ES029929 | PLoS Genet (2023 Jul) |
37410774
|
2023 |
| Common genetic variation impacts stress response in the brain. | Seah, Carina; Signer, Rebecca; Deans, Michael; Bader, Heather; Rusielewicz, Tom; Hicks, Emily ... | R01ES033630 | bioRxiv (2023 Dec 28) |
38234801
|
2023 |
| Comorbidity Profiles of Posttraumatic Stress Disorder Across the Medical Phenome. | Hicks, Emily M; Niarchou, Maria; Goleva, Slavina; Kabir, Dia; Ciarcia, Julia; PTSD & Trauma EHR ... | R01ES033630 | medRxiv (2023 Aug 28) |
37693435
|
2023 |
| Dietary stress remodels the genetic architecture of lifespan variation in outbred Drosophila. | Pallares, Luisa F; Lea, Amanda J; Han, Clair; Filippova, Elena V; Andolfatto, Peter; Ayroles, ... | R01ES029929 | Nat Genet (2023 Jan) |
36550361
|
2023 |
| Disease risk and healthcare utilization among ancestrally diverse groups in the Los Angeles region. | Caggiano, Christa; Boudaie, Arya; Shemirani, Ruhollah; Mefford, Joel; Petter, Ella; Chiu, Alec ... | R01ES029929 | Nat Med (2023 Jul) |
37464048
|
2023 |
| DNA methylation QTL mapping across diverse human tissues provides molecular links between genetic va ... | Oliva, Meritxell; Demanelis, Kathryn; Lu, Yihao; Chernoff, Meytal; Jasmine, Farzana; Ahsan, Ha ... | R35ES028379 | Nat Genet (2023 Jan) |
36510025
|
2023 |
| Environmental radiation exposure at Chornobyl has not systematically affected the genomes or mutagen ... | Tintori, Sophia C; Çağlar, Derin; Ortiz, Patrick; Chyzhevskyi, Ihor; Mousseau, Timothy A; Rockm ... | R01ES029930 | bioRxiv (2023 May 30) |
37398032
|
2023 |
| Evaluation of imputation performance of multiple reference panels in a Pakistani population. | Xu, Jiayi; Liu, Dongjing; Hassan, Arsalan; Genovese, Giulio; Cote, Alanna C; Fennessy, Brian; ... | R01ES033630 | medRxiv (2023 Dec 26) |
38234809
|
2023 |
| FUS Unveiled in Mitochondrial DNA Repair and Targeted Ligase-1 Expression Rescues Repair-Defects in ... | Kodavati, Manohar; Wang, Haibo; Guo, Wenting; Mitra, Joy; Hegde, Pavana M; Provasek, Vincent; ... | R01ES012512 | Res Sq (2023 Jul 12) |
37502965
|
2023 |
| Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at sin ... | Resztak, Justyna A; Wei, Julong; Zilioli, Samuele; Sendler, Edward; Alazizi, Adnan; Mair-Meijer ... | R01ES033634 | Genome Res (2023 Jun) |
37442575
|
2023 |
| Genomic insights into the comorbidity between type 2 diabetes and schizophrenia. | Arruda, Ana Luiza; Khandaker, Golam M; Morris, Andrew P; Smith, George Davey; Huckins, Laura M; ... | R01ES033630 | medRxiv (2023 Oct 16) |
37905000
|
2023 |
| GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms a ... | Dand, Nick; Stuart, Philip E; Bowes, John; Ellinghaus, David; Nititham, Joanne; Saklatvala, Ja ... | R01ES033634 | medRxiv (2023 Oct 05) |
37873414
|
2023 |
| Health equity innovation in precision medicine: Current challenges and future directions. | Ory, Marcia G; Adepoju, Omolola E; Ramos, Kenneth S; Silva, Patrick S; Vollmer Dahlke, Deborah | R01ES034542 | Front Public Health (2023) |
36875406
|
2023 |
| Identification of astrocyte regulators by nucleic acid cytometry. | Clark, Iain C; Wheeler, Michael A; Lee, Hong-Gyun; Li, Zhaorong; Sanmarco, Liliana M; Thaploo, ... | R01ES025530, R01ES032323 | Nature (2023 Feb) |
36599367
|
2023 |
| Increased body mass index is linked to systemic inflammation through altered chromatin co-accessibil ... | Garske, Kristina M; Kar, Asha; Comenho, Caroline; Balliu, Brunilda; Pan, David Z; Bhagat, Yash ... | F32ES034668 | Nat Commun (2023 Jul 14) |
37452040
|
2023 |
| Independently evolved pollution resistance in four killifish populations is largely explained by few ... | Miller, Jeffrey T; Clark, Bryan W; Reid, Noah M; Karchner, Sibel I; Roach, Jennifer L; Hahn, M ... | R01ES032323, R01ES033888, R01ES033888, T32ES007059 | bioRxiv (2023 Apr 08) |
37066319
|
2023 |
| Integrating genetics and transcriptomics to study major depressive disorder: a conceptual framework, ... | Hicks, Emily M; Seah, Carina; Cote, Alanna; Marchese, Shelby; Brennand, Kristen J; Nestler, Er ... | R01ES033630 | Transl Psychiatry (2023 Apr 19) |
37076454
|
2023 |
| Leveraging base-pair mammalian constraint to understand genetic variation and human disease. | Sullivan, Patrick F; Meadows, Jennifer R S; Gazal, Steven; Phan, BaDoi N; Li, Xue; Genereux, D ... | R01ES033630 | Science (2023 Apr 28) |
37104612
|
2023 |
| Mapping genomic regulation of kidney disease and traits through high-resolution and interpretable eQ ... | Han, Seong Kyu; McNulty, Michelle T; Benway, Christopher J; Wen, Pei; Greenberg, Anya; Onuchic- ... | R01ES033634 | Nat Commun (2023 Apr 19) |
37076491
|
2023 |
| Metabolome-wide Mendelian randomization characterizes heterogeneous and shared causal effects of met ... | Yin, Xianyong; Li, Jack; Bose, Debraj; Okamoto, Jeffrey; Kwon, Annie; Jackson, Anne U; Silva, ... | R01ES033634 | medRxiv (2023 Jun 29) |
37425837
|
2023 |
| Network and Microcircuitry Development in Human Brain Organoids. | Puppo, Francesca; Muotri, Alysson Renato | R01ES033636 | Biol Psychiatry (2023 Apr 01) |
35981907
|
2023 |
| Non-additive effects of schizophrenia risk genes reflect convergent downstream function. | Deans, Pj Michael; Seah, Carina; Johnson, Jessica; Gonzalez, Judit Garcia; Townsley, Kayla; Cao ... | R01ES033630 | medRxiv (2023 Mar 21) |
36993466
|
2023 |
| Novel and improved Caenorhabditis briggsae gene models generated by community curation. | Moya, Nicolas D; Stevens, Lewis; Miller, Isabella R; Sokol, Chloe E; Galindo, Joseph L; Bardas, ... | R01ES029930 | bioRxiv (2023 May 18) |
37292880
|
2023 |
| PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of a ... | Linnerbauer, Mathias; Beyer, Tobias; Nirschl, Lucy; Farrenkopf, Daniel; Lößlein, Lena; Vandrey, ... | R01ES025530, R01ES032323 | Nat Commun (2023 Sep 09) |
37689786
|
2023 |
| Probabilistic integration of transcriptome-wide association studies and colocalization analysis iden ... | Okamoto, Jeffrey; Wang, Lijia; Yin, Xianyong; Luca, Francesca; Pique-Regi, Roger; Helms, Adam; ... | R01ES033634 | Am J Hum Genet (2023 Jan 05) |
36608684
|
2023 |
| Refining risk estimates for lead in drinking water based on the impact of genetics and diet on blood ... | Cuomo, Danila; Nitcher, Megan; Barba, Estefania; Feinberg, Andrew P; Rusyn, Ivan; Chiu, Weihsu ... | P30ES029067, P42ES027704, R01ES029911 | Toxicol Sci (2023 Jul 28) |
37243727
|
2023 |
| Sequencing-based fine-mapping and in silico functional characterization of the 10q24.32 arsenic meta ... | Chernoff, Meytal Batya; Delgado, Dayana; Tong, Lin; Chen, Lin; Oliva, Meritxell; Tamayo, Lizet ... | P30ES009089, P30ES027792, P42ES033719, R01ES032638, R35ES028379 | PLoS Genet (2023 Jan) |
36668670
|
2023 |
| Simultaneous modeling of multivariate heterogeneous responses and heteroskedasticity via a two-stage ... | Ting, Bryan W; Wright, Fred A; Zhou, Yi-Hui | R01ES029911, R01ES033243, T32ES007329 | Biom J (2023 Aug) |
37212427
|
2023 |
| Somatic loss of the Y chromosome is associated with arsenic exposure among Bangladeshi men. | Demanelis, Kathryn; Delgado, Dayana A; Tong, Lin; Jasmine, Farzana; Ahmed, Alauddin; Islam, Ta ... | P30ES027792, R35ES028379 | Int J Epidemiol (2023 Aug 02) |
36130227
|
2023 |
| Stem Cell Models for Context-Specific Modeling in Psychiatric Disorders. | Seah, Carina; Huckins, Laura M; Brennand, Kristen J | R01ES033630 | Biol Psychiatry (2023 Apr 01) |
36658083
|
2023 |
| The Role of MAP3K1 in the Development of the Female Reproductive Tract. | Kimura, Eiki; Mongan, Maureen; Xiao, Bo; Wang, Jingjing; Carreira, Vinicius S; Bolon, Brad; Zh ... | P30ES006096, R21ES033342 | bioRxiv (2023 Apr 21) |
37131749
|
2023 |
| Thoughtful Phenotype Definitions Empower Participants and Power Studies. | Huckins, Laura M | R01ES033630 | Complex Psychiatry (2023) |
37032718
|
2023 |
| Trauma Matters: Integrating Genetic and Environmental Components of PTSD. | Marchese, Shelby; Huckins, Laura M | R01ES033630 | Adv Genet (Hoboken) (2023 Sep) |
37766803
|
2023 |
| A Population-Based Human In Vitro Approach to Quantify Inter-Individual Variability in Responses to ... | Ford, Lucie C; Jang, Suji; Chen, Zunwei; Zhou, Yi-Hui; Gallins, Paul J; Wright, Fred A; Chiu, ... | P30ES029067, P42ES027704, R01ES029911, T32ES026568 | Toxics (2022 Aug 01) |
36006120
|
2022 |
| A resource for integrated genomic analysis of the human liver. | Zhou, Yi-Hui; Gallins, Paul J; Etheridge, Amy S; Jima, Dereje; Scholl, Elizabeth; Wright, Fred ... | P30ES010126, P42ES027704, R01ES029911 | Sci Rep (2022 Sep 07) |
36071064
|
2022 |
| C. elegans toxicant responses vary among genetically diverse individuals. | Widmayer, Samuel J; Crombie, Timothy A; Nyaanga, Joy N; Evans, Kathryn S; Andersen, Erik C | R01ES029930 | Toxicology (2022 Sep) |
35995124
|
2022 |
| Characterization of population variability of 1,3-butadiene derived protein adducts in humans and mi ... | Boysen, Gunnar; Rusyn, Ivan; Chiu, Weihsueh A; Wright, Fred A | P30ES029067, P42ES027704, R01ES029911 | Regul Toxicol Pharmacol (2022 Jul) |
35469930
|
2022 |
| Chromosome-Level Genome Assembly of the Bioluminescent Cardinalfish Siphamia tubifer: An Emerging Mo ... | Gould, A L; Henderson, J B; Lam, A W | R01ES029930 | Genome Biol Evol (2022 Apr 10) |
35349687
|
2022 |
| Chromosome-Level Reference Genomes for Two Strains of Caenorhabditis briggsae: An Improved Platform ... | Stevens, Lewis; Moya, Nicolas D; Tanny, Robyn E; Gibson, Sophia B; Tracey, Alan; Na, Huimin; C ... | R01ES029930 | Genome Biol Evol (2022 Apr 10) |
35348662
|
2022 |
| Cross-trait assortative mating is widespread and inflates genetic correlation estimates. | Border, Richard; Athanasiadis, Georgios; Buil, Alfonso; Schork, Andrew J; Cai, Na; Young, Alex ... | R01ES029929 | Science (2022 Nov 18) |
36395242
|
2022 |
| Cumulative Risk Meets Inter-Individual Variability: Probabilistic Concentration Addition of Complex ... | Jang, Suji; Ford, Lucie C; Rusyn, Ivan; Chiu, Weihsueh A | P30ES029067, P42ES027704, R01ES029911, T32ES026568 | Toxics (2022 Sep 20) |
36287830
|
2022 |
| Diverse environmental perturbations reveal the evolution and context-dependency of genetic effects o ... | Lea, Amanda J; Peng, Julie; Ayroles, Julien F | R01ES029929 | Genome Res (2022 Oct) |
36229124
|
2022 |
| Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogen ... | Goodman, Samantha; Chappell, Grace; Guyton, Kathryn Z; Pogribny, Igor P; Rusyn, Ivan | R01ES029911, T32ES026568 | Mutat Res Rev Mutat Res (2022) |
35690411
|
2022 |
| Evaluating the power and limitations of genome-wide association studies in Caenorhabditis elegans. | Widmayer, Samuel J; Evans, Kathryn S; Zdraljevic, Stefan; Andersen, Erik C | R01ES029930 | G3 (Bethesda) (2022 Jul 06) |
35536194
|
2022 |
| Exploring the clinical and genetic associations of adult weight trajectories using electronic health ... | Xu, Jiayi; Johnson, Jessica S; Signer, Rebecca; Eating Disorders Working Group of the Psychiatric ... | R01ES033630 | Lancet Digit Health (2022 Aug) |
35780037
|
2022 |
| Identification of environmental factors that promote intestinal inflammation. | Sanmarco, Liliana M; Chao, Chun-Cheih; Wang, Yu-Chao; Kenison, Jessica E; Li, Zhaorong; Rone, ... | R01ES025530, R01ES032323 | Nature (2022 Nov) |
36266581
|
2022 |
| Inherited genetic effects on arsenic metabolism: A comparison of effects on arsenic species measured ... | Tamayo, Lizeth I; Kumarasinghe, Yohhan; Tong, Lin; Balac, Olgica; Ahsan, Habibul; Gamble, Mary ... | R35ES028379 | Environ Epidemiol (2022 Dec) |
36530933
|
2022 |
| Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite ... | Yin, Xianyong; Bose, Debraj; Kwon, Annie; Hanks, Sarah C; Jackson, Anne U; Stringham, Heather ... | R01ES033634 | Am J Hum Genet (2022 Oct 06) |
36055244
|
2022 |
| Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fa ... | Nagumalli, Suresh K; Willett, Rose A; de Conti, Aline; Tryndyak, Volodymyr P; Avigan, Mark I; d ... | R01ES029911 | J Nutr Biochem (2022 Nov) |
35858665
|
2022 |
| Massively parallel analysis of human 3' UTRs reveals that AU-rich element length and registration pr ... | Siegel, David A; Le Tonqueze, Olivier; Biton, Anne; Zaitlen, Noah; Erle, David J | R01ES029929 | G3 (Bethesda) (2022 Jan 04) |
34849835
|
2022 |
| Mendelian randomization accounting for complex correlated horizontal pleiotropy while elucidating sh ... | Cheng, Qing; Zhang, Xiao; Chen, Lin S; Liu, Jin | R35ES028379 | Nat Commun (2022 Oct 30) |
36310177
|
2022 |
| Methylation risk scores are associated with a collection of phenotypes within electronic health reco ... | Thompson, Mike; Hill, Brian L; Rakocz, Nadav; Chiang, Jeffrey N; Geschwind, Daniel; Sankararama ... | R01ES029929 | NPJ Genom Med (2022 Aug 25) |
36008412
|
2022 |
| Model systems and organisms for addressing inter- and intra-species variability in risk assessment. | Rusyn, Ivan; Chiu, Weihsueh A; Wright, Fred A | P30ES029067, P42ES027704, R01ES029911 | Regul Toxicol Pharmacol (2022 Jul) |
35636685
|
2022 |
| Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific gluc ... | Seah, Carina; Breen, Michael S; Rusielewicz, Tom; Bader, Heather N; Xu, Changxin; Hunter, Chri ... | R01ES033630 | Nat Neurosci (2022 Nov) |
36266471
|
2022 |
| Multi-context genetic modeling of transcriptional regulation resolves novel disease loci. | Thompson, Mike; Gordon, Mary Grace; Lu, Andrew; Tandon, Anchit; Halperin, Eran; Gusev, Alexand ... | R01ES029929 | Nat Commun (2022 Sep 28) |
36171194
|
2022 |
| Natural genetic variation as a tool for discovery in Caenorhabditis nematodes. | Andersen, Erik C; Rockman, Matthew V | R01ES029930 | Genetics (2022 Jan 04) |
35134197
|
2022 |
| Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the ... | Tryndyak, Volodymyr P; Willett, Rose A; Avigan, Mark I; Sanyal, Arun J; Beland, Frederick A; Ru ... | R01ES029911 | Epigenetics (2022 Nov) |
35324388
|
2022 |
| Purification and Characterization of Human DNA Ligase IIIα Complexes After Expression in Insect Cell ... | Rashid, Ishtiaque; Tsai, Miaw-Sheue; Sverzhinsky, Aleksandr; Hlaing, Aye Su; Shih, Brian; Thwin ... | R01ES012512 | Methods Mol Biol (2022) |
35290642
|
2022 |
| Relative Telomere Length Change in Colorectal Carcinoma and Its Association with Tumor Characteristi ... | Kibriya, Muhammad G; Raza, Maruf; Kamal, Mohammed; Haq, Zahidul; Paul, Rupash; Mareczko, Andre ... | P30ES027792, R35ES028379 | Cancers (Basel) (2022 Apr 30) |
35565379
|
2022 |
| Sequencing and assembling bear genomes: the bare necessities. | Willey, Courtney; Korstanje, Ron | R01ES029916 | Front Zool (2022 Nov 30) |
36451195
|
2022 |
| Serum concentrations of legacy and emerging per- and polyfluoroalkyl substances in the Anniston Comm ... | Petriello, Michael C; Mottaleb, M Abdul; Serio, Tara C; Balyan, Bharat; Cave, Matthew C; Pavuk, ... | P30ES026529, P30ES030283, P42ES007380, P42ES023716, R35ES028379 | Environ Int (2022 Jan) |
34763231
|
2022 |
| Study Protocol: Interactive Dynamics of Coral Reef Fisheries and the Nutrition Transition in Kiribat ... | Golden, Christopher D; Ayroles, Julien; Eurich, Jacob G; Gephart, Jessica A; Seto, Katherine L; ... | R01ES029929 | Front Public Health (2022) |
35719655
|
2022 |
| The aryl hydrocarbon receptor: A predominant mediator for the toxicity of emerging dioxin-like compo ... | Zhang, Wanglong; Xie, Heidi Qunhui; Li, Yunping; Zhou, Mingxi; Zhou, Zhiguang; Wang, Renjun; H ... | R01ES032323 | J Hazard Mater (2022 Mar 15) |
34952507
|
2022 |
| The impact of genetic background on mouse models of kidney disease. | Bufi, Rei; Korstanje, Ron | R01ES029916 | Kidney Int (2022 Jul) |
35429495
|
2022 |
| Using population selection and sequencing to characterize natural variation of starvation resistance ... | Webster, Amy K; Chitrakar, Rojin; Powell, Maya; Chen, Jingxian; Fisher, Kinsey; Tanny, Robyn E ... | R01ES029930 | Elife (2022 Jun 21) |
35727141
|
2022 |
| Utilizing a Population-Genetic Framework to Test for Gene-Environment Interactions between Zebrafish ... | Thunga, Preethi; Truong, Lisa; Rericha, Yvonne; Du, Jane La; Morshead, Mackenzie; Tanguay, Rob ... | P30ES010126, P30ES030287, P42ES016465, R01ES033243, T32ES007060 | Toxics (2022 Dec 09) |
36548602
|
2022 |
| What next for eating disorder genetics? Replacing myths with facts to sharpen our understanding. | Huckins, Laura M; Signer, Rebecca; Johnson, Jessica; Wu, Ya-Ke; Mitchell, Karen S; Bulik, Cynt ... | R01ES033630 | Mol Psychiatry (2022 Oct) |
35595976
|
2022 |
| A model and test for coordinated polygenic epistasis in complex traits. | Sheppard, Brooke; Rappoport, Nadav; Loh, Po-Ru; Sanders, Stephan J; Zaitlen, Noah; Dahl, Andy | R01ES029929 | Proc Natl Acad Sci U S A (2021 Apr 13) |
33833052
|
2021 |
| A polygenic-score-based approach for identification of gene-drug interactions stratifying breast can ... | Marderstein, Andrew R; Kulm, Scott; Peng, Cheng; Tamimi, Rulla; Clark, Andrew G; Elemento, Oli ... | R01ES029929 | Am J Hum Genet (2021 Sep 02) |
34363748
|
2021 |
| An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα wit ... | Hammel, Michal; Rashid, Ishtiaque; Sverzhinsky, Aleksandr; Pourfarjam, Yasin; Tsai, Miaw-Sheue; ... | R01ES012512 | Nucleic Acids Res (2021 01 11) |
33330937
|
2021 |
| Balancing selection maintains hyper-divergent haplotypes in Caenorhabditis elegans. | Lee, Daehan; Zdraljevic, Stefan; Stevens, Lewis; Wang, Ye; Tanny, Robyn E; Crombie, Timothy A; ... | R01ES029930 | Nat Ecol Evol (2021 Jun) |
33820969
|
2021 |
| CCmed: cross-condition mediation analysis for identifying replicable trans-associations mediated by ... | Yang, Fan; Gleason, Kevin J; Wang, Jiebiao; Duan, Jubao; He, Xin; Pierce, Brandon L; Chen, Li ... | R35ES028379 | Bioinformatics (2021 Sep 09) |
33647928
|
2021 |
| Comprehensive cell type decomposition of circulating cell-free DNA with CelFiE. | Caggiano, Christa; Celona, Barbara; Garton, Fleur; Mefford, Joel; Black, Brian L; Henderson, R ... | R01ES029929 | Nat Commun (2021 05 11) |
33976150
|
2021 |
| Constructing germline research cohorts from the discarded reads of clinical tumor sequences. | Gusev, Alexander; Groha, Stefan; Taraszka, Kodi; Semenov, Yevgeniy R; Zaitlen, Noah | R01ES029929 | Genome Med (2021 11 08) |
34749793
|
2021 |
| Design and analysis of CRISPR-based underdominance toxin-antidote gene drives. | Champer, Jackson; Champer, Samuel E; Kim, Isabel K; Clark, Andrew G; Messer, Philipp W | R01ES029929 | Evol Appl (2021 Apr) |
33897820
|
2021 |
| Direct interaction of DNA repair protein tyrosyl DNA phosphodiesterase 1 and the DNA ligase III cata ... | Rashid, Ishtiaque; Hammel, Michal; Sverzhinsky, Aleksandr; Tsai, Miaw-Sheue; Pascal, John M; Ta ... | R01ES012512 | J Biol Chem (2021 Aug) |
34181949
|
2021 |
| Disentangling selection on genetically correlated polygenic traits via whole-genome genealogies. | Stern, Aaron J; Speidel, Leo; Zaitlen, Noah A; Nielsen, Rasmus | R01ES029929 | Am J Hum Genet (2021 Feb 04) |
33440170
|
2021 |
| easyXpress: An R package to analyze and visualize high-throughput C. elegans microscopy data generat ... | Nyaanga, Joy; Crombie, Timothy A; Widmayer, Samuel J; Andersen, Erik C | R01ES029930 | PLoS One (2021) |
34383778
|
2021 |
| Effects of GSTT1 Genotype on the Detoxification of 1,3-Butadiene Derived Diepoxide and Formation of ... | Boysen, Gunnar; Arora, Rashi; Degner, Amanda; Vevang, Karin R; Chao, Christopher; Rodriguez, F ... | R01ES029911 | Chem Res Toxicol (2021 01 18) |
33381973
|
2021 |
| Erratum: "Rare, protein-altering variants in AS3MT and arsenic metabolism efficiency: a multi-popula ... | Delgado, Dayana A; Chernoff, Meytal; Huang, Lei; Tong, Lin; Chen, Lin; Jasmine, Farzana; Shink ... | R35ES028379 | Environ Health Perspect (2021 May) |
34038222
|
2021 |
| From QTL to gene: C. elegans facilitates discoveries of the genetic mechanisms underlying natural va ... | Evans, Kathryn S; van Wijk, Marijke H; McGrath, Patrick T; Andersen, Erik C; Sterken, Mark G | R01ES029930 | Trends Genet (2021 10) |
34229867
|
2021 |
| Genetically Increased Telomere Length and Aging-Related Traits in the U.K. Biobank. | Demanelis, Kathryn; Tong, Lin; Pierce, Brandon L | R35ES028379 | J Gerontol A Biol Sci Med Sci (2021 01 01) |
31603979
|
2021 |
| Intra- and Inter-Species Variability in Urinary N7-(1-Hydroxy-3-buten-2-yl)guanine Adducts Following ... | Erber, Luke; Goodman, Samantha; Wright, Fred A; Chiu, Weihsueh A; Tretyakova, Natalia Y; Rusyn, ... | R01ES029911, T32ES026568 | Chem Res Toxicol (2021 Nov 15) |
34726909
|
2021 |
| Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores tha ... | Võsa, Urmo; Claringbould, Annique; Westra, Harm-Jan; Bonder, Marc Jan; Deelen, Patrick; Zeng, ... | R35ES028379 | Nat Genet (2021 Sep) |
34475573
|
2021 |
| Ligase 1 is a predictor of platinum resistance and its blockade is synthetically lethal in XRCC1 def ... | Ali, Reem; Alabdullah, Muslim; Algethami, Mashael; Alblihy, Adel; Miligy, Islam; Shoqafi, Ahme ... | R01ES012512 | Theranostics (2021) |
34373746
|
2021 |
| Meta-analysis suggests the microbiome responds to Evolve and Resequence experiments in Drosophila me ... | Henry, Lucas P; Ayroles, Julien F | R01ES029929 | BMC Microbiol (2021 Apr 09) |
33836662
|
2021 |
| Mouse Genetic Reference Populations: Cellular Platforms for Integrative Systems Genetics. | Swanzey, Emily; O'Connor, Callan; Reinholdt, Laura G | R01ES029916 | Trends Genet (2021 Mar) |
33010949
|
2021 |
| Proteome-Wide Profiling of Cellular Targets Modified by Dopamine Metabolites Using a Bio-Orthogonall ... | Hurben, Alexander K; Erber, Luke N; Tretyakova, Natalia Y; Doran, Todd M | R01ES023350, R01ES029911 | ACS Chem Biol (2021 Nov 19) |
34726906
|
2021 |
| Quantitative NanoLC/NSI+-HRMS Method for 1,3-Butadiene Induced bis-N7-guanine DNA-DNA Cross-Links in ... | Erber, Luke; Goodman, Samantha; Jokipii Krueger, Caitlin C; Rusyn, Ivan; Tretyakova, Natalia | R01ES029911, T32ES026568 | Toxics (2021 Oct 02) |
34678943
|
2021 |
| Rare, Protein-Altering Variants in AS3MT and Arsenic Metabolism Efficiency: A Multi-Population Assoc ... | Delgado, Dayana A; Chernoff, Meytal; Huang, Lei; Tong, Lin; Chen, Lin; Jasmine, Farzana; Shink ... | P30ES009089, P30ES027792, R35ES028379 | Environ Health Perspect (2021 Apr) |
33826413
|
2021 |
| Selfing is the safest sex for Caenorhabditis tropicalis. | Noble, Luke M; Yuen, John; Stevens, Lewis; Moya, Nicolas; Persaud, Riaad; Moscatelli, Marc; Ja ... | R01ES029930 | Elife (2021 Jan 11) |
33427200
|
2021 |
| Suppression gene drive in continuous space can result in unstable persistence of both drive and wild ... | Champer, Jackson; Kim, Isabel K; Champer, Samuel E; Clark, Andrew G; Messer, Philipp W | R01ES029929 | Mol Ecol (2021 02) |
33404162
|
2021 |
| Xenobiotic metabolism and transport in Caenorhabditis elegans. | Hartman, Jessica H; Widmayer, Samuel J; Bergemann, Christina M; King, Dillon E; Morton, Katheri ... | P42ES010356, R01ES029930, T32ES021432 | J Toxicol Environ Health B Crit Rev (2021 Feb 17) |
33616007
|
2021 |
| A CRISPR homing gene drive targeting a haplolethal gene removes resistance alleles and successfully ... | Champer, Jackson; Yang, Emily; Lee, Esther; Liu, Jingxian; Clark, Andrew G; Messer, Philipp W | R01ES029929 | Proc Natl Acad Sci U S A (2020 Sep 29) |
32929034
|
2020 |
| A Robust Method Uncovers Significant Context-Specific Heritability in Diverse Complex Traits. | Dahl, Andy; Nguyen, Khiem; Cai, Na; Gandal, Michael J; Flint, Jonathan; Zaitlen, Noah | R01ES029929 | Am J Hum Genet (2020 Jan 02) |
31901249
|
2020 |
| Assessing the impact of arsenic metabolism efficiency on DNA methylation using Mendelian randomizati ... | DiGiovanni, Anthony; Demanelis, Kathryn; Tong, Lin; Argos, Maria; Shinkle, Justin; Jasmine, Fa ... | P30ES009089, P30ES027792, R35ES028379 | Environ Epidemiol (2020 Apr) |
32337471
|
2020 |
| Computational and experimental performance of CRISPR homing gene drive strategies with multiplexed g ... | Champer, Samuel E; Oh, Suh Yeon; Liu, Chen; Wen, Zhaoxin; Clark, Andrew G; Messer, Philipp W; ... | R01ES029929 | Sci Adv (2020 Mar) |
32181354
|
2020 |
| Determinants of telomere length across human tissues. | Demanelis, Kathryn; Jasmine, Farzana; Chen, Lin S; Chernoff, Meytal; Tong, Lin; Delgado, Dayan ... | P30ES027792, R35ES028379 | Science (2020 Sep 11) |
32913074
|
2020 |
| Efficient Estimation and Applications of Cross-Validated Genetic Predictions to Polygenic Risk Score ... | Mefford, Joel; Park, Danny; Zheng, Zhili; Ko, Arthur; Ala-Korpela, Mika; Laakso, Markku; Pajuk ... | R01ES029929 | J Comput Biol (2020 04) |
32077750
|
2020 |
| Genetic Determinants of Reduced Arsenic Metabolism Efficiency in the 10q24.32 Region Are Associated ... | Chernoff, Meytal; Tong, Lin; Demanelis, Kathryn; Vander Griend, Donald; Ahsan, Habib; Pierce, ... | P30ES027792, R35ES028379 | Toxicol Sci (2020 08 01) |
32433756
|
2020 |
| Human DNA ligases in replication and repair. | Sallmyr, Annahita; Rashid, Ishtiaque; Bhandari, Seema Khattri; Naila, Tasmin; Tomkinson, Alan E | R01ES012512 | DNA Repair (Amst) (2020 09) |
33087274
|
2020 |
| Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patt ... | Keele, Gregory R; Quach, Bryan C; Israel, Jennifer W; Chappell, Grace A; Lewis, Lauren; Safi, ... | P30ES010126, P30ES025128, R01ES029911 | PLoS Genet (2020 Jan) |
31961859
|
2020 |
| Interindividual Differences in DNA Adduct Formation and Detoxification of 1,3-Butadiene-Derived Epox ... | Degner, Amanda; Arora, Rashi; Erber, Luke; Chao, Christopher; Peterson, Lisa A; Tretyakova, Na ... | R01ES029911 | Chem Res Toxicol (2020 07 20) |
32237725
|
2020 |
| Massively parallel techniques for cataloguing the regulome of the human brain. | Townsley, Kayla G; Brennand, Kristen J; Huckins, Laura M | R01ES033630 | Nat Neurosci (2020 Dec) |
33199899
|
2020 |
| Modeling epistasis in mice and yeast using the proportion of two or more distinct genetic background ... | Rau, Christoph D; Gonzales, Natalia M; Bloom, Joshua S; Park, Danny; Ayroles, Julien; Palmer, ... | R01ES029929 | PLoS Genet (2020 10) |
33104702
|
2020 |
| Natural variation in the sequestosome-related gene, sqst-5, underlies zinc homeostasis in Caenorhabd ... | Evans, Kathryn S; Zdraljevic, Stefan; Stevens, Lewis; Collins, Kimberly; Tanny, Robyn E; Anders ... | R01ES029930 | PLoS Genet (2020 11) |
33175833
|
2020 |
| Primo: integration of multiple GWAS and omics QTL summary statistics for elucidation of molecular me ... | Gleason, Kevin J; Yang, Fan; Pierce, Brandon L; He, Xin; Chen, Lin S | R35ES028379 | Genome Biol (2020 Sep 11) |
32912334
|
2020 |
| Research Participants' Attitudes towards Receiving Information on Genetic Susceptibility to Arsenic ... | Tamayo, Lizeth I; Lin, Hannah; Ahmed, Alauddin; Shahriar, Hasan; Hasan, Rabiul; Sarwar, Golam; ... | P30ES027792, R35ES028379 | Public Health Genomics (2020) |
32069464
|
2020 |
| The cadmium-responsive gene, cdr-6, does not influence Caenorhabditis elegans responses to exogenous ... | Evans, Kathryn S; Andersen, Erik C | R01ES029930 | MicroPubl Biol (2020 Sep 14) |
33005884
|
2020 |
| The Evolution of Variance Control. | Bruijning, Marjolein; Metcalf, C Jessica E; Jongejans, Eelke; Ayroles, Julien F | R01ES029929 | Trends Ecol Evol (2020 Jan) |
31519463
|
2020 |
| The Gene scb-1 Underlies Variation in Caenorhabditis elegans Chemotherapeutic Responses. | Evans, Kathryn S; Andersen, Erik C | R01ES029930 | G3 (Bethesda) (2020 07 07) |
32385045
|
2020 |
| TM3'seq: A Tagmentation-Mediated 3' Sequencing Approach for Improving Scalability of RNAseq Experime ... | Pallares, Luisa F; Picard, Serge; Ayroles, Julien F | R01ES029929 | G3 (Bethesda) (2020 01 07) |
31676507
|
2020 |
| Using Genetic and Species Diversity to Tackle Kidney Disease. | Garrett, Michael R; Korstanje, Ron | R01ES029916 | Trends Genet (2020 07) |
32362446
|
2020 |
| 1HN, 13C, and 15N backbone resonance assignments of the human DNA ligase 3 DNA-binding domain (resid ... | Roth, Braden M; Varney, Kristen M; Yang, Hui; Weber, David J; Tomkinson, Alan E | R01ES012512 | Biomol NMR Assign (2019 10) |
31093909
|
2019 |
| 1HN, 13C, and 15N resonance assignments of human calmodulin bound to a peptide derived from the STRA ... | Varney, Kristen M; Wilder, Paul T; Godoy-Ruiz, Raquel; Mancia, Filippo; Weber, David J | R01ES012512 | Biomol NMR Assign (2019 10) |
30875027
|
2019 |
| A missense variant in FTCD is associated with arsenic metabolism and toxicity phenotypes in Banglade ... | Pierce, Brandon L; Tong, Lin; Dean, Samantha; Argos, Maria; Jasmine, Farzana; Rakibuz-Zaman, M ... | P30ES009089, P30ES027792, R35ES028379 | PLoS Genet (2019 Mar) |
30893314
|
2019 |
| A Novel Gene Underlies Bleomycin-Response Variation in Caenorhabditis elegans. | Brady, Shannon C; Zdraljevic, Stefan; Bisaga, Karol W; Tanny, Robyn E; Cook, Daniel E; Lee, Da ... | R01ES029930 | Genetics (2019 Aug) |
31171655
|
2019 |
| Association of Arsenic Exposure with Whole Blood DNA Methylation: An Epigenome-Wide Study of Banglad ... | Demanelis, Kathryn; Argos, Maria; Tong, Lin; Shinkle, Justin; Sabarinathan, Mekala; Rakibuz-Zam ... | P30ES009089, P30ES027792, R35ES028379 | Environ Health Perspect (2019 May) |
31135185
|
2019 |
| Genetic and environmental perturbations lead to regulatory decoherence. | Lea, Amanda; Subramaniam, Meena; Ko, Arthur; Lehtimäki, Terho; Raitoharju, Emma; Kähönen, Mika ... | R01ES029929 | Elife (2019 Mar 05) |
30834892
|
2019 |
| Natural variation in C. elegans arsenic toxicity is explained by differences in branched chain amino ... | Zdraljevic, Stefan; Fox, Bennett William; Strand, Christine; Panda, Oishika; Tenjo, Francisco J ... | R01ES029930 | Elife (2019 04 08) |
30958264
|
2019 |
| Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the Mouse. | Lewis, Lauren; Borowa-Mazgaj, Barbara; de Conti, Aline; Chappell, Grace A; Luo, Yu-Syuan; Bodna ... | R01ES029911 | Chem Res Toxicol (2019 05 20) |
30990016
|
2019 |
| Sex-specific differences in genotoxic and epigenetic effects of 1,3-butadiene among mouse tissues. | Lewis, Lauren; Chappell, Grace A; Kobets, Tetyana; O'Brian, Bridget E; Sangaraju, Dewakar; Kosy ... | P30ES025128, P30ES029067, R01ES029911 | Arch Toxicol (2019 Mar) |
30552462
|
2019 |
| SUMOning the base excision repair machinery for differentiation. | Wiest, Nathaniel E; Tomkinson, Alan E | R01ES012512 | EMBO J (2019 Jan 03) |
30545824
|
2019 |
| The contribution of parent-to-offspring transmission of telomeres to the heritability of telomere le ... | Delgado, Dayana A; Zhang, Chenan; Gleason, Kevin; Demanelis, Kathryn; Chen, Lin S; Gao, Jianju ... | R35ES028379 | Hum Genet (2019 Jan) |
30536049
|
2019 |
| The effect of age on DNA methylation in whole blood among Bangladeshi men and women. | Jansen, Rick J; Tong, Lin; Argos, Maria; Jasmine, Farzana; Rakibuz-Zaman, Muhammad; Sarwar, Go ... | R35ES028379 | BMC Genomics (2019 Sep 10) |
31506065
|
2019 |
| Tightly linked antagonistic-effect loci underlie polygenic phenotypic variation in C. elegans. | Bernstein, Max R; Zdraljevic, Stefan; Andersen, Erik C; Rockman, Matthew V | R01ES029930 | Evol Lett (2019 Oct) |
31636939
|
2019 |
| Using Collaborative Cross Mouse Population to Fill Data Gaps in Risk Assessment: A Case Study of Pop ... | Luo, Yu-Syuan; Cichocki, Joseph A; Hsieh, Nan-Hung; Lewis, Lauren; Wright, Fred A; Threadgill, ... | P30ES029067, P42ES027704, R01ES029911 | Environ Health Perspect (2019 06) |
31246107
|
2019 |
| A novel pooled-sample multiplex luminex assay for high-throughput measurement of relative telomere l ... | Jasmine, Farzana; Shinkle, Justin; Sabarinathan, Mekala; Ahsan, Habibul; Pierce, Brandon L; Kib ... | R35ES028379 | Am J Hum Biol (2018 Jul) |
29527774
|
2018 |
| A study of telomere length, arsenic exposure, and arsenic toxicity in a Bangladeshi cohort. | Zhang, Chenan; Kibriya, Muhammad G; Jasmine, Farzana; Roy, Shantanu; Gao, Jianjun; Sabarinathan ... | R35ES028379 | Environ Res (2018 07) |
29567420
|
2018 |
| Co-occurring expression and methylation QTLs allow detection of common causal variants and shared bi ... | Pierce, Brandon L; Tong, Lin; Argos, Maria; Demanelis, Kathryn; Jasmine, Farzana; Rakibuz-Zaman ... | R35ES028379 | Nat Commun (2018 Feb 23) |
29476079
|
2018 |
| Genome-wide association study of telomere length among South Asians identifies a second RTEL1 associ ... | Delgado, Dayana A; Zhang, Chenan; Chen, Lin S; Gao, Jianjun; Roy, Shantanu; Shinkle, Justin; S ... | R35ES028379 | J Med Genet (2018 01) |
29151059
|
2018 |
| Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Scl ... | Wang, Haibo; Guo, Wenting; Mitra, Joy; Hegde, Pavana M; Vandoorne, Tijs; Eckelmann, Bradley J; ... | R01ES012512 | Nat Commun (2018 Sep 11) |
30206235
|
2018 |
| Repair of DNA double-strand breaks by mammalian alternative end-joining pathways. | Sallmyr, Annahita; Tomkinson, Alan E | R01ES012512 | J Biol Chem (2018 07 06) |
29530982
|
2018 |
| Screening for gene-environment (G×E) interaction using omics data from exposed individuals: an appli ... | Argos, Maria; Tong, Lin; Roy, Shantanu; Sabarinathan, Mekala; Ahmed, Alauddin; Islam, Md Tariq ... | P30ES009089, R35ES028379 | Mamm Genome (2018 Feb) |
29453499
|
2018 |
| Incorporation of Biological Knowledge Into the Study of Gene-Environment Interactions. | Ritchie, Marylyn D; Davis, Joe R; Aschard, Hugues; Battle, Alexis; Conti, David; Du, Mengmeng; ... | P30ES007048, P30ES013508, R35ES028379 | Am J Epidemiol (2017 Oct 01) |
28978191
|
2017 |
| Lessons Learned From Past Gene-Environment Interaction Successes. | Ritz, Beate R; Chatterjee, Nilanjan; Garcia-Closas, Montserrat; Gauderman, W James; Pierce, Bra ... | P30ES007048, R35ES028379 | Am J Epidemiol (2017 Oct 01) |
28978190
|
2017 |
| Optimization of Native and Formaldehyde iPOND Techniques for Use in Suspension Cells. | Wiest, Nathaniel E; Tomkinson, Alan E | R01ES012512 | Methods Enzymol (2017) |
28645366
|
2017 |
| Structure-activity relationships among DNA ligase inhibitors: Characterization of a selective uncomp ... | Howes, Timothy R L; Sallmyr, Annahita; Brooks, Rhys; Greco, George E; Jones, Darin E; Matsumoto ... | R01ES012512 | DNA Repair (Amst) (2017 Dec) |
29078112
|
2017 |
| The association between telomere length and mortality in Bangladesh. | Dean, Samantha G; Zhang, Chenan; Gao, Jianjun; Roy, Shantanu; Shinkle, Justin; Sabarinathan, M ... | R35ES028379 | Aging (Albany NY) (2017 Jun 15) |
28630379
|
2017 |
| The Human Ligase IIIα-XRCC1 Protein Complex Performs DNA Nick Repair after Transient Unwrapping of N ... | Cannan, Wendy J; Rashid, Ishtiaque; Tomkinson, Alan E; Wallace, Susan S; Pederson, David S | R01ES012512 | J Biol Chem (2017 Mar 31) |
28184006
|
2017 |
| Inhibiting Mitochondrial DNA Ligase IIIα Activates Caspase 1-Dependent Apoptosis in Cancer Cells. | Sallmyr, Annahita; Matsumoto, Yoshihiro; Roginskaya, Vera; Van Houten, Bennett; Tomkinson, Alan ... | R01ES012512 | Cancer Res (2016 Sep 15) |
27503931
|
2016 |
| SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV. | Greco, George E; Matsumoto, Yoshihiro; Brooks, Rhys C; Lu, Zhengfei; Lieber, Michael R; Tomkins ... | R01ES012512 | DNA Repair (Amst) (2016 07) |
27235626
|
2016 |
| Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining. | Kukshal, Vandna; Kim, In-Kwon; Hura, Gregory L; Tomkinson, Alan E; Tainer, John A; Ellenberger, ... | R01ES012512 | Nucleic Acids Res (2015 Aug 18) |
26130724
|
2015 |
| Chromosomal translocations in human cells are generated by canonical nonhomologous end-joining. | Ghezraoui, Hind; Piganeau, Marion; Renouf, Benjamin; Renaud, Jean-Baptiste; Sallmyr, Annahita; ... | R01ES012512 | Mol Cell (2014 Sep 18) |
25201414
|
2014 |
| DNA ligases as therapeutic targets. | Tomkinson, Alan E; Howes, Timothy R L; Wiest, Nathaniel E | R01ES012512 | Transl Cancer Res (2013 Jun) |
24224145
|
2013 |
| Structure and function of the DNA ligases encoded by the mammalian LIG3 gene. | Tomkinson, Alan E; Sallmyr, Annahita | R01ES012512 | Gene (2013 Dec 01) |
24013086
|
2013 |
| Targeting abnormal DNA double-strand break repair in tyrosine kinase inhibitor-resistant chronic mye ... | Tobin, L A; Robert, C; Rapoport, A P; Gojo, I; Baer, M R; Tomkinson, A E; Rassool, F V | R01ES012512 | Oncogene (2013 Apr 04) |
22641215
|
2013 |
| Increased risk of lung cancer associated with a functionally impaired polymorphic variant of the hum ... | Dey, Sanjib; Maiti, Amit K; Hegde, Muralidhar L; Hegde, Pavana M; Boldogh, Istvan; Sarkar, Par ... | R01ES012512 | DNA Repair (Amst) (2012 Jun 01) |
22497777
|
2012 |
| Targeting abnormal DNA repair in therapy-resistant breast cancers. | Tobin, Lisa A; Robert, Carine; Nagaria, Pratik; Chumsri, Saranya; Twaddell, William; Ioffe, Ol ... | R01ES012512 | Mol Cancer Res (2012 Jan) |
22112941
|
2012 |
| The interaction between polynucleotide kinase phosphatase and the DNA repair protein XRCC1 is critic ... | Della-Maria, Julie; Hegde, Muralidhar L; McNeill, Daniel R; Matsumoto, Yoshihiro; Tsai, Miaw-Sh ... | R01ES012512 | J Biol Chem (2012 Nov 09) |
22992732
|
2012 |
| The nucleotide sequence, DNA damage location, and protein stoichiometry influence the base excision ... | Goula, Agathi-Vasiliki; Pearson, Christopher E; Della Maria, Julie; Trottier, Yvon; Tomkinson, ... | R01ES012512 | Biochemistry (2012 May 8) |
22497302
|
2012 |
| Human Mre11/human Rad50/Nbs1 and DNA ligase IIIalpha/XRCC1 protein complexes act together in an alte ... | Della-Maria, Julie; Zhou, Yi; Tsai, Miaw-Sheue; Kuhnlein, Jeff; Carney, James P; Paull, Tanya ... | R01ES012512 | J Biol Chem (2011 Sep 30) |
21816818
|
2011 |
| Nucleosome disruption by DNA ligase III-XRCC1 promotes efficient base excision repair. | Odell, Ian D; Barbour, Joy-El; Murphy, Drew L; Della-Maria, Julie A; Sweasy, Joann B; Tomkinson ... | R01ES012512 | Mol Cell Biol (2011 Nov) |
21930793
|
2011 |
| Replication protein A safeguards genome integrity by controlling NER incision events. | Overmeer, René M; Moser, Jill; Volker, Marcel; Kool, Hanneke; Tomkinson, Alan E; van Zeeland, ... | R01ES012512 | J Cell Biol (2011 Feb 07) |
21282463
|
2011 |
| Functional capacity of XRCC1 protein variants identified in DNA repair-deficient Chinese hamster ova ... | Berquist, Brian R; Singh, Dharmendra Kumar; Fan, Jinshui; Kim, Daemyung; Gillenwater, Elizabeth ... | R01ES012512 | Nucleic Acids Res (2010 Aug) |
20385586
|
2010 |
| Human DNA ligase III recognizes DNA ends by dynamic switching between two DNA-bound states. | Cotner-Gohara, Elizabeth; Kim, In-Kwon; Hammel, Michal; Tainer, John A; Tomkinson, Alan E; Elle ... | R01ES012512 | Biochemistry (2010 Jul 27) |
20518483
|
2010 |
| Targeting abnormal DNA double strand break repair in cancer. | Rassool, Feyruz V; Tomkinson, Alan E | R01ES012512 | Cell Mol Life Sci (2010 Nov) |
20697770
|
2010 |
| Distinct kinetics of human DNA ligases I, IIIalpha, IIIbeta, and IV reveal direct DNA sensing abilit ... | Chen, Xi; Ballin, Jeff D; Della-Maria, Julie; Tsai, Miaw-Sheue; White, Elizabeth J; Tomkinson, ... | R01ES012512 | DNA Repair (Amst) (2009 Aug 6) |
19589734
|
2009 |
| Eukaryotic DNA ligases: structural and functional insights. | Ellenberger, Tom; Tomkinson, Alan E | R01ES012512 | Annu Rev Biochem (2008) |
18518823
|
2008 |
| Identification and validation of human DNA ligase inhibitors using computer-aided drug design. | Zhong, Shijun; Chen, Xi; Zhu, Xiao; Dziegielewska, Barbara; Bachman, Kurtis E; Ellenberger, To ... | R01ES012512 | J Med Chem (2008 Aug 14) |
18630893
|
2008 |
| Rational design of human DNA ligase inhibitors that target cellular DNA replication and repair. | Chen, Xi; Zhong, Shijun; Zhu, Xiao; Dziegielewska, Barbara; Ellenberger, Tom; Wilson, Gerald M ... | R01ES012512 | Cancer Res (2008 May 1) |
18451142
|
2008 |
| Two DNA-binding and nick recognition modules in human DNA ligase III. | Cotner-Gohara, Elizabeth; Kim, In-Kwon; Tomkinson, Alan E; Ellenberger, Tom | R01ES012512 | J Biol Chem (2008 Apr 18) |
18238776
|
2008 |
| Up-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repai ... | Sallmyr, Annahita; Tomkinson, Alan E; Rassool, Feyruz V | R01ES012512 | Blood (2008 Aug 15) |
18524993
|
2008 |
| ATM mediates oxidative stress-induced dephosphorylation of DNA ligase IIIalpha. | Dong, Zhiwan; Tomkinson, Alan E | R01ES012512 | Nucleic Acids Res (2006) |
17040896
|
2006 |
| DNA ligases: structure, reaction mechanism, and function. | Tomkinson, Alan E; Vijayakumar, Sangeetha; Pascal, John M; Ellenberger, Tom | R01ES012512 | Chem Rev (2006 Feb) |
16464020
|
2006 |
| Human DNA ligases I, III, and IV-purification and new specific assays for these enzymes. | Chen, Xi; Pascal, John; Vijayakumar, Sangeetha; Wilson, Gerald M; Ellenberger, Tom; Tomkinson, ... | R01ES012512 | Methods Enzymol (2006) |
16793394
|
2006 |
| NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in h ... | Das, Aditi; Wiederhold, Lee; Leppard, John B; Kedar, Padmini; Prasad, Rajendra; Wang, Huxian; ... | R01ES012512 | DNA Repair (Amst) (2006 Dec 09) |
16982218
|
2006 |
| Translocation of XRCC1 and DNA ligase IIIalpha from centrosomes to chromosomes in response to DNA da ... | Okano, Satoshi; Lan, Li; Tomkinson, Alan E; Yasui, Akira | R01ES012512 | Nucleic Acids Res (2005) |
15653642
|
2005 |