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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| Characterization of caffeine response regulatory variants in vascular endothelial cells. | Boye, Carly; Kalita, Cynthia A; Findley, Anthony S; Alazizi, Adnan; Wei, Julong; Wen, Xiaoquan ... | R01ES033634 | Elife (2024 Feb 09) |
38334359
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2024 |
| Eating disorders: are gut microbiota to blame? | Xu, Jiayi; Carroll, Ian M; Huckins, Laura M | R01ES033630 | Trends Mol Med (2024 Apr) |
38040602
|
2024 |
| Environmental radiation exposure at Chornobyl has not systematically affected the genomes or chemica ... | Tintori, Sophia C; Çağlar, Derin; Ortiz, Patrick; Chyzhevskyi, Ihor; Mousseau, Timothy A; Rockm ... | R01ES029930 | Proc Natl Acad Sci U S A (2024 Mar 12) |
38442158
|
2024 |
| FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in ... | Kodavati, Manohar; Wang, Haibo; Guo, Wenting; Mitra, Joy; Hegde, Pavana M; Provasek, Vincent; ... | R01ES012512 | Nat Commun (2024 Mar 09) |
38461154
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2024 |
| Genetically Regulated Gene Expression in the Brain Associated With Chronic Pain: Relationships With ... | Johnston, Keira J A; Cote, Alanna C; Hicks, Emily; Johnson, Jessica; Huckins, Laura M | R01ES033630 | Biol Psychiatry (2024 Apr 15) |
37678542
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2024 |
| Genomic insights into the comorbidity between type 2 diabetes and schizophrenia. | Arruda, Ana Luiza; Khandaker, Golam M; Morris, Andrew P; Smith, George Davey; Huckins, Laura M; ... | R01ES033630 | Schizophrenia (Heidelb) (2024 Feb 21) |
38383672
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2024 |
| Independently evolved pollution resistance in four killifish populations is largely explained by few ... | Miller, Jeffrey T; Clark, Bryan W; Reid, Noah M; Karchner, Sibel I; Roach, Jennifer L; Hahn, M ... | R01ES032323, R01ES033888, R01ES033888, T32ES007059 | Evol Appl (2024 Jan) |
38293268
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2024 |
| Long Interspersed Nuclear Element-1 Analytes in Extracellular Vesicles as Tools for Molecular Diagno ... | Bowers, Emma C; Cavalcante, Alexandre M; Nguyen, Kimberly; Li, Can; Wang, Yingshan; El-Zein, R ... | R01ES034542 | Int J Mol Sci (2024 Jan 18) |
38256242
|
2024 |
| Loss of GTF2I promotes neuronal apoptosis and synaptic reduction in human cellular models of neurode ... | Adams, Jason W; Vinokur, Annabelle; de Souza, Janaína S; Austria, Charles; Guerra, Bruno S; Her ... | R01ES033636 | Cell Rep (2024 Mar 26) |
38416640
|
2024 |
| Mammalian DNA ligases; roles in maintaining genome integrity. | Sallmyr, Annahita; Bhandari, Seema Khattri; Naila, Tasmin; Tomkinson, Alan E | R01ES012512 | J Mol Biol (2024 Jan 01) |
37714297
|
2024 |
| MAP3K1 regulates female reproductive tract development. | Kimura, Eiki; Mongan, Maureen; Xiao, Bo; Christianto, Antonius; Wang, Jingjing; Carreira, Vini ... | R21ES033342 | Dis Model Mech (2024 Mar 01) |
38501211
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2024 |
| Open Science Practices in Psychiatric Genetics: A Primer. | Kępińska, Adrianna P; Johnson, Jessica S; Huckins, Laura M | R01ES033630 | Biol Psychiatry Glob Open Sci (2024 Jan) |
38298792
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2024 |
| Reassessing the modularity of gene co-expression networks using the Stochastic Block Model. | Melo, Diogo; Pallares, Luisa F; Ayroles, Julien F | R01ES029929 | bioRxiv (2024 Apr 10) |
37398186
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2024 |
| Returning personal genetic information on susceptibility to arsenic toxicity to research participant ... | Tamayo, Lizeth I; Haque, Syed Emdadul; Islam, Tariqul; Ahmed, Alauddin; Rahman, Moziber; Horayr ... | R35ES028379 | Environ Res (2024 Jan 01) |
37879393
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2024 |
| The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology. | Linnerbauer, Mathias; Lößlein, Lena; Vandrey, Oliver; Peter, Anne; Han, Yanan; Tsaktanis, Than ... | R01ES025530, R01ES032323 | Nat Immunol (2024 Mar) |
38409259
|
2024 |
| The Impact of Inherited Genetic Variation on DNA Methylation in Prostate Cancer and Benign Tissues o ... | Delgado, Dayana; Gillard, Marc; Tong, Lin; Demanelis, Kathryn; Oliva, Meritxell; Gleason, Kevi ... | R35ES028379 | Cancer Epidemiol Biomarkers Prev (2024 Apr 03) |
38294689
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2024 |
| WHAMM functions in kidney reabsorption and polymerizes actin to promote autophagosomal membrane clos ... | Coulter, Alyssa M; Cortés, Valerie; Theodore, Corey J; Cianciolo, Rachel E; Korstanje, Ron; Cam ... | R01ES029916 | bioRxiv (2024 Jan 23) |
38328079
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2024 |
| A nonparametric alternative to the Cochran-Armitage trend test in genetic case-control association s ... | Manning, Sydney E; Ku, Hung-Chih; Dluzen, Douglas F; Xing, Chao; Zhou, Zhengyang | R03ES034138 | PLoS One (2023) |
36730335
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2023 |
| A Varying Coefficient Model to Jointly Test Genetic and Gene-Environment Interaction Effects. | Zhou, Zhengyang; Ku, Hung-Chih; Manning, Sydney E; Zhang, Ming; Xing, Chao | R03ES034138 | Behav Genet (2023 Jul) |
36622576
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2023 |
| Adaptations to water stress and pastoralism in the Turkana of northwest Kenya. | Lea, A J; Caldas, I V; Garske, K M; Echwa, J; Gurven, M; Handley, C; Kahumbu, J; Kamau; Kinyu ... | F32ES034668 | bioRxiv (2023 Jan 19) |
36711473
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2023 |
| Applying an evolutionary mismatch framework to understand disease susceptibility. | Lea, Amanda J; Clark, Andrew G; Dahl, Andrew W; Devinsky, Orrin; Garcia, Angela R; Golden, Chr ... | R01ES029929 | PLoS Biol (2023 Sep) |
37695771
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2023 |
| BAP1 is a novel regulator of HIF-1α. | Bononi, Angela; Wang, Qian; Zolondick, Alicia A; Bai, Fang; Steele-Tanji, Mika; Suarez, Joelle ... | R01ES030948 | Proc Natl Acad Sci U S A (2023 Jan 24) |
36656861
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2023 |
| Better together: Non-additive interactions between schizophrenia risk genes. | Deans, P J Michael; Brennand, Kristen J | R01ES033630 | Cell Genom (2023 Sep 13) |
37719145
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2023 |
| Capturing continuous, long timescale behavioral changes in Drosophila melanogaster postural data. | McKenzie-Smith, Grace C; Wolf, Scott W; Ayroles, Julien F; Shaevitz, Joshua W | R01ES029929 | ArXiv (2023 Sep 07) |
37731659
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2023 |
| Cell morphology QTL reveal gene by environment interactions in a genetically diverse cell population ... | O'Connor, Callan; Keele, Gregory R; Martin, Whitney; Stodola, Timothy; Gatti, Daniel; Hoffman, ... | R01ES029916 | bioRxiv (2023 Nov 18) |
38014303
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2023 |
| Characterizing the landscape of gene expression variance in humans. | Wolf, Scott; Melo, Diogo; Garske, Kristina M; Pallares, Luisa F; Lea, Amanda J; Ayroles, Julie ... | F32ES034668, R01ES029929 | PLoS Genet (2023 Jul) |
37410774
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2023 |
| Common genetic variation impacts stress response in the brain. | Seah, Carina; Signer, Rebecca; Deans, Michael; Bader, Heather; Rusielewicz, Tom; Hicks, Emily ... | R01ES033630 | bioRxiv (2023 Dec 28) |
38234801
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2023 |
| Comorbidity Profiles of Posttraumatic Stress Disorder Across the Medical Phenome. | Hicks, Emily M; Niarchou, Maria; Goleva, Slavina; Kabir, Dia; Ciarcia, Julia; PTSD & Trauma EHR ... | R01ES033630 | medRxiv (2023 Aug 28) |
37693435
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2023 |
| Did the Ban on Asbestos Reduce the Incidence of Mesothelioma? | Carbone, Michele; Yang, Haining; Pass, Harvey I; Taioli, Emanuela | R01ES030948 | J Thorac Oncol (2023 Jun) |
37210180
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2023 |
| Dietary stress remodels the genetic architecture of lifespan variation in outbred Drosophila. | Pallares, Luisa F; Lea, Amanda J; Han, Clair; Filippova, Elena V; Andolfatto, Peter; Ayroles, ... | R01ES029929 | Nat Genet (2023 Jan) |
36550361
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2023 |
| Disease risk and healthcare utilization among ancestrally diverse groups in the Los Angeles region. | Caggiano, Christa; Boudaie, Arya; Shemirani, Ruhollah; Mefford, Joel; Petter, Ella; Chiu, Alec ... | R01ES029929 | Nat Med (2023 Jul) |
37464048
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2023 |
| DNA methylation QTL mapping across diverse human tissues provides molecular links between genetic va ... | Oliva, Meritxell; Demanelis, Kathryn; Lu, Yihao; Chernoff, Meytal; Jasmine, Farzana; Ahsan, Ha ... | R35ES028379 | Nat Genet (2023 Jan) |
36510025
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2023 |
| Environmental radiation exposure at Chornobyl has not systematically affected the genomes or mutagen ... | Tintori, Sophia C; Çağlar, Derin; Ortiz, Patrick; Chyzhevskyi, Ihor; Mousseau, Timothy A; Rockm ... | R01ES029930 | bioRxiv (2023 May 30) |
37398032
|
2023 |
| Evaluation of imputation performance of multiple reference panels in a Pakistani population. | Xu, Jiayi; Liu, Dongjing; Hassan, Arsalan; Genovese, Giulio; Cote, Alanna C; Fennessy, Brian; ... | R01ES033630 | medRxiv (2023 Dec 26) |
38234809
|
2023 |
| External control arms: COVID-19 reveals the merits of using real world evidence in real-time for cli ... | Silva, Patrick; Janjan, Nora; Ramos, Kenneth S; Udeani, George; Zhong, Lixian; Ory, Marcia G; ... | R01ES034542 | Front Med (Lausanne) (2023) |
37484840
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2023 |
| FUS Unveiled in Mitochondrial DNA Repair and Targeted Ligase-1 Expression Rescues Repair-Defects in ... | Kodavati, Manohar; Wang, Haibo; Guo, Wenting; Mitra, Joy; Hegde, Pavana M; Provasek, Vincent; ... | R01ES012512 | Res Sq (2023 Jul 12) |
37502965
|
2023 |
| Genomic insights into the comorbidity between type 2 diabetes and schizophrenia. | Arruda, Ana Luiza; Khandaker, Golam M; Morris, Andrew P; Smith, George Davey; Huckins, Laura M; ... | R01ES033630 | medRxiv (2023 Oct 16) |
37905000
|
2023 |
| GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms a ... | Dand, Nick; Stuart, Philip E; Bowes, John; Ellinghaus, David; Nititham, Joanne; Saklatvala, Ja ... | R01ES033634 | medRxiv (2023 Oct 05) |
37873414
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2023 |
| Health equity innovation in precision medicine: Current challenges and future directions. | Ory, Marcia G; Adepoju, Omolola E; Ramos, Kenneth S; Silva, Patrick S; Vollmer Dahlke, Deborah | R01ES034542 | Front Public Health (2023) |
36875406
|
2023 |
| HMGB1 released by mesothelial cells drives the development of asbestos-induced mesothelioma. | Suarez, Joelle S; Novelli, Flavia; Goto, Keisuke; Ehara, Michiko; Steele, Mika; Kim, Jin-Hee; ... | R01ES030948 | Proc Natl Acad Sci U S A (2023 Sep 26) |
37729199
|
2023 |
| Identification of astrocyte regulators by nucleic acid cytometry. | Clark, Iain C; Wheeler, Michael A; Lee, Hong-Gyun; Li, Zhaorong; Sanmarco, Liliana M; Thaploo, ... | R01ES025530, R01ES032323 | Nature (2023 Feb) |
36599367
|
2023 |
| Increased body mass index is linked to systemic inflammation through altered chromatin co-accessibil ... | Garske, Kristina M; Kar, Asha; Comenho, Caroline; Balliu, Brunilda; Pan, David Z; Bhagat, Yash ... | F32ES034668 | Nat Commun (2023 Jul 14) |
37452040
|
2023 |
| Independently evolved pollution resistance in four killifish populations is largely explained by few ... | Miller, Jeffrey T; Clark, Bryan W; Reid, Noah M; Karchner, Sibel I; Roach, Jennifer L; Hahn, M ... | R01ES032323, R01ES033888, R01ES033888, T32ES007059 | bioRxiv (2023 Apr 08) |
37066319
|
2023 |
| Integrating genetics and transcriptomics to study major depressive disorder: a conceptual framework, ... | Hicks, Emily M; Seah, Carina; Cote, Alanna; Marchese, Shelby; Brennand, Kristen J; Nestler, Er ... | R01ES033630 | Transl Psychiatry (2023 Apr 19) |
37076454
|
2023 |
| Mapping genomic regulation of kidney disease and traits through high-resolution and interpretable eQ ... | Han, Seong Kyu; McNulty, Michelle T; Benway, Christopher J; Wen, Pei; Greenberg, Anya; Onuchic- ... | R01ES033634 | Nat Commun (2023 Apr 19) |
37076491
|
2023 |
| Network and Microcircuitry Development in Human Brain Organoids. | Puppo, Francesca; Muotri, Alysson Renato | R01ES033636 | Biol Psychiatry (2023 Apr 01) |
35981907
|
2023 |
| Non-additive effects of schizophrenia risk genes reflect convergent downstream function. | Deans, Pj Michael; Seah, Carina; Johnson, Jessica; Gonzalez, Judit Garcia; Townsley, Kayla; Cao ... | R01ES033630 | medRxiv (2023 Mar 21) |
36993466
|
2023 |
| Novel and improved Caenorhabditis briggsae gene models generated by community curation. | Moya, Nicolas D; Stevens, Lewis; Miller, Isabella R; Sokol, Chloe E; Galindo, Joseph L; Bardas, ... | R01ES029930 | bioRxiv (2023 May 18) |
37292880
|
2023 |
| PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of a ... | Linnerbauer, Mathias; Beyer, Tobias; Nirschl, Lucy; Farrenkopf, Daniel; Lößlein, Lena; Vandrey, ... | R01ES025530, R01ES032323 | Nat Commun (2023 Sep 09) |
37689786
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2023 |
| Preventive and therapeutic opportunities: targeting BAP1 and/or HMGB1 pathways to diminish the burde ... | Carbone, Michele; Minaai, Michael; Takinishi, Yasutaka; Pagano, Ian; Yang, Haining | R01ES030948 | J Transl Med (2023 Oct 25) |
37880686
|
2023 |
| Probabilistic integration of transcriptome-wide association studies and colocalization analysis iden ... | Okamoto, Jeffrey; Wang, Lijia; Yin, Xianyong; Luca, Francesca; Pique-Regi, Roger; Helms, Adam; ... | R01ES033634 | Am J Hum Genet (2023 Jan 05) |
36608684
|
2023 |
| Refining risk estimates for lead in drinking water based on the impact of genetics and diet on blood ... | Cuomo, Danila; Nitcher, Megan; Barba, Estefania; Feinberg, Andrew P; Rusyn, Ivan; Chiu, Weihsu ... | P30ES029067, P42ES027704, P42ES027704, R01ES029911 | Toxicol Sci (2023 Jul 28) |
37243727
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2023 |
| Sequencing-based fine-mapping and in silico functional characterization of the 10q24.32 arsenic meta ... | Chernoff, Meytal Batya; Delgado, Dayana; Tong, Lin; Chen, Lin; Oliva, Meritxell; Tamayo, Lizet ... | P30ES009089, P42ES033719, R01ES032638, R35ES028379 | PLoS Genet (2023 Jan) |
36668670
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2023 |
| Simultaneous modeling of multivariate heterogeneous responses and heteroskedasticity via a two-stage ... | Ting, Bryan W; Wright, Fred A; Zhou, Yi-Hui | R01ES029911, T32ES007329 | Biom J (2023 Aug) |
37212427
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2023 |
| Somatic loss of the Y chromosome is associated with arsenic exposure among Bangladeshi men. | Demanelis, Kathryn; Delgado, Dayana A; Tong, Lin; Jasmine, Farzana; Ahmed, Alauddin; Islam, Ta ... | R35ES028379 | Int J Epidemiol (2023 Aug 02) |
36130227
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2023 |
| Stem Cell Models for Context-Specific Modeling in Psychiatric Disorders. | Seah, Carina; Huckins, Laura M; Brennand, Kristen J | R01ES033630 | Biol Psychiatry (2023 Apr 01) |
36658083
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2023 |
| The Role of MAP3K1 in the Development of the Female Reproductive Tract. | Kimura, Eiki; Mongan, Maureen; Xiao, Bo; Wang, Jingjing; Carreira, Vinicius S; Bolon, Brad; Zh ... | R21ES033342 | bioRxiv (2023 Apr 21) |
37131749
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2023 |
| Trauma Matters: Integrating Genetic and Environmental Components of PTSD. | Marchese, Shelby; Huckins, Laura M | R01ES033630 | Adv Genet (Hoboken) (2023 Sep) |
37766803
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2023 |
| A Population-Based Human In Vitro Approach to Quantify Inter-Individual Variability in Responses to ... | Ford, Lucie C; Jang, Suji; Chen, Zunwei; Zhou, Yi-Hui; Gallins, Paul J; Wright, Fred A; Chiu, ... | P30ES029067, P42ES027704, P42ES027704, R01ES029911, T32ES026568 | Toxics (2022 Aug 01) |
36006120
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2022 |
| A resource for integrated genomic analysis of the human liver. | Zhou, Yi-Hui; Gallins, Paul J; Etheridge, Amy S; Jima, Dereje; Scholl, Elizabeth; Wright, Fred ... | P42ES027704, P42ES027704, R01ES029911 | Sci Rep (2022 Sep 07) |
36071064
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2022 |
| C. elegans toxicant responses vary among genetically diverse individuals. | Widmayer, Samuel J; Crombie, Timothy A; Nyaanga, Joy N; Evans, Kathryn S; Andersen, Erik C | R01ES029930 | Toxicology (2022 Sep) |
35995124
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2022 |
| Characterization of population variability of 1,3-butadiene derived protein adducts in humans and mi ... | Boysen, Gunnar; Rusyn, Ivan; Chiu, Weihsueh A; Wright, Fred A | P30ES029067, P42ES027704, P42ES027704, R01ES029911 | Regul Toxicol Pharmacol (2022 Jul) |
35469930
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2022 |
| Chromosome-Level Genome Assembly of the Bioluminescent Cardinalfish Siphamia tubifer: An Emerging Mo ... | Gould, A L; Henderson, J B; Lam, A W | R01ES029930 | Genome Biol Evol (2022 Apr 10) |
35349687
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2022 |
| Chromosome-Level Reference Genomes for Two Strains of Caenorhabditis briggsae: An Improved Platform ... | Stevens, Lewis; Moya, Nicolas D; Tanny, Robyn E; Gibson, Sophia B; Tracey, Alan; Na, Huimin; C ... | R01ES029930 | Genome Biol Evol (2022 Apr 10) |
35348662
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2022 |
| Cross-trait assortative mating is widespread and inflates genetic correlation estimates. | Border, Richard; Athanasiadis, Georgios; Buil, Alfonso; Schork, Andrew J; Cai, Na; Young, Alex ... | R01ES029929 | Science (2022 Nov 18) |
36395242
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2022 |
| Cumulative Risk Meets Inter-Individual Variability: Probabilistic Concentration Addition of Complex ... | Jang, Suji; Ford, Lucie C; Rusyn, Ivan; Chiu, Weihsueh A | P30ES029067, P42ES027704, P42ES027704, R01ES029911, T32ES026568 | Toxics (2022 Sep 20) |
36287830
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2022 |
| Diverse environmental perturbations reveal the evolution and context-dependency of genetic effects o ... | Lea, Amanda J; Peng, Julie; Ayroles, Julien F | R01ES029929 | Genome Res (2022 Oct) |
36229124
|
2022 |
| Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogen ... | Goodman, Samantha; Chappell, Grace; Guyton, Kathryn Z; Pogribny, Igor P; Rusyn, Ivan | R01ES029911, T32ES026568 | Mutat Res Rev Mutat Res (2022) |
35690411
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2022 |
| Evaluating the power and limitations of genome-wide association studies in Caenorhabditis elegans. | Widmayer, Samuel J; Evans, Kathryn S; Zdraljevic, Stefan; Andersen, Erik C | R01ES029930 | G3 (Bethesda) (2022 Jul 06) |
35536194
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2022 |
| Exploring the clinical and genetic associations of adult weight trajectories using electronic health ... | Xu, Jiayi; Johnson, Jessica S; Signer, Rebecca; Eating Disorders Working Group of the Psychiatric ... | R01ES033630 | Lancet Digit Health (2022 Aug) |
35780037
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2022 |
| Identification of environmental factors that promote intestinal inflammation. | Sanmarco, Liliana M; Chao, Chun-Cheih; Wang, Yu-Chao; Kenison, Jessica E; Li, Zhaorong; Rone, ... | R01ES025530, R01ES032323 | Nature (2022 Nov) |
36266581
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2022 |
| Inherited genetic effects on arsenic metabolism: A comparison of effects on arsenic species measured ... | Tamayo, Lizeth I; Kumarasinghe, Yohhan; Tong, Lin; Balac, Olgica; Ahsan, Habibul; Gamble, Mary ... | R35ES028379 | Environ Epidemiol (2022 Dec) |
36530933
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2022 |
| Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite ... | Yin, Xianyong; Bose, Debraj; Kwon, Annie; Hanks, Sarah C; Jackson, Anne U; Stringham, Heather ... | R01ES033634 | Am J Hum Genet (2022 Oct 06) |
36055244
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2022 |
| Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fa ... | Nagumalli, Suresh K; Willett, Rose A; de Conti, Aline; Tryndyak, Volodymyr P; Avigan, Mark I; d ... | R01ES029911 | J Nutr Biochem (2022 Nov) |
35858665
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2022 |
| Massively parallel analysis of human 3' UTRs reveals that AU-rich element length and registration pr ... | Siegel, David A; Le Tonqueze, Olivier; Biton, Anne; Zaitlen, Noah; Erle, David J | R01ES029929 | G3 (Bethesda) (2022 Jan 04) |
34849835
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2022 |
| Medical and Surgical Care of Patients With Mesothelioma and Their Relatives Carrying Germline BAP1 M ... | Carbone, Michele; Pass, Harvey I; Ak, Guntulu; Alexander Jr, H Richard; Baas, Paul; Baumann, F ... | R01ES030948 | J Thorac Oncol (2022 Jul) |
35462085
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2022 |
| Mendelian randomization accounting for complex correlated horizontal pleiotropy while elucidating sh ... | Cheng, Qing; Zhang, Xiao; Chen, Lin S; Liu, Jin | R35ES028379 | Nat Commun (2022 Oct 30) |
36310177
|
2022 |
| Methylation risk scores are associated with a collection of phenotypes within electronic health reco ... | Thompson, Mike; Hill, Brian L; Rakocz, Nadav; Chiang, Jeffrey N; Geschwind, Daniel; Sankararama ... | R01ES029929 | NPJ Genom Med (2022 Aug 25) |
36008412
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2022 |
| Model systems and organisms for addressing inter- and intra-species variability in risk assessment. | Rusyn, Ivan; Chiu, Weihsueh A; Wright, Fred A | P30ES029067, P42ES027704, P42ES027704, R01ES029911 | Regul Toxicol Pharmacol (2022 Jul) |
35636685
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2022 |
| Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific gluc ... | Seah, Carina; Breen, Michael S; Rusielewicz, Tom; Bader, Heather N; Xu, Changxin; Hunter, Chri ... | R01ES033630 | Nat Neurosci (2022 Nov) |
36266471
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2022 |
| Multi-context genetic modeling of transcriptional regulation resolves novel disease loci. | Thompson, Mike; Gordon, Mary Grace; Lu, Andrew; Tandon, Anchit; Halperin, Eran; Gusev, Alexand ... | R01ES029929 | Nat Commun (2022 Sep 28) |
36171194
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2022 |
| Natural genetic variation as a tool for discovery in Caenorhabditis nematodes. | Andersen, Erik C; Rockman, Matthew V | R01ES029930 | Genetics (2022 Jan 04) |
35134197
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2022 |
| Naturally occurring metals in unregulated domestic wells in Nevada, USA. | Arienzo, Monica M; Saftner, Daniel; Bacon, Steven N; Robtoy, Erika; Neveux, Iva; Schlauch, Kar ... | R01ES030948 | Sci Total Environ (2022 Dec 10) |
36029812
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2022 |
| Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the ... | Tryndyak, Volodymyr P; Willett, Rose A; Avigan, Mark I; Sanyal, Arun J; Beland, Frederick A; Ru ... | R01ES029911 | Epigenetics (2022 Nov) |
35324388
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2022 |
| Purification and Characterization of Human DNA Ligase IIIα Complexes After Expression in Insect Cell ... | Rashid, Ishtiaque; Tsai, Miaw-Sheue; Sverzhinsky, Aleksandr; Hlaing, Aye Su; Shih, Brian; Thwin ... | R01ES012512 | Methods Mol Biol (2022) |
35290642
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2022 |
| Relative Telomere Length Change in Colorectal Carcinoma and Its Association with Tumor Characteristi ... | Kibriya, Muhammad G; Raza, Maruf; Kamal, Mohammed; Haq, Zahidul; Paul, Rupash; Mareczko, Andre ... | R35ES028379 | Cancers (Basel) (2022 Apr 30) |
35565379
|
2022 |
| Sequencing and assembling bear genomes: the bare necessities. | Willey, Courtney; Korstanje, Ron | R01ES029916 | Front Zool (2022 Nov 30) |
36451195
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2022 |
| Serum concentrations of legacy and emerging per- and polyfluoroalkyl substances in the Anniston Comm ... | Petriello, Michael C; Mottaleb, M Abdul; Serio, Tara C; Balyan, Bharat; Cave, Matthew C; Pavuk, ... | P30ES020957, P30ES026529, P30ES030283, P42ES007380, P42ES023716, R35ES028379 | Environ Int (2022 Jan) |
34763231
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2022 |
| Study Protocol: Interactive Dynamics of Coral Reef Fisheries and the Nutrition Transition in Kiribat ... | Golden, Christopher D; Ayroles, Julien; Eurich, Jacob G; Gephart, Jessica A; Seto, Katherine L; ... | R01ES029929 | Front Public Health (2022) |
35719655
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2022 |
| The aryl hydrocarbon receptor: A predominant mediator for the toxicity of emerging dioxin-like compo ... | Zhang, Wanglong; Xie, Heidi Qunhui; Li, Yunping; Zhou, Mingxi; Zhou, Zhiguang; Wang, Renjun; H ... | R01ES032323 | J Hazard Mater (2022 Mar 15) |
34952507
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2022 |
| The impact of genetic background on mouse models of kidney disease. | Bufi, Rei; Korstanje, Ron | R01ES029916 | Kidney Int (2022 Jul) |
35429495
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2022 |
| Using population selection and sequencing to characterize natural variation of starvation resistance ... | Webster, Amy K; Chitrakar, Rojin; Powell, Maya; Chen, Jingxian; Fisher, Kinsey; Tanny, Robyn E ... | R01ES029930 | Elife (2022 Jun 21) |
35727141
|
2022 |
| Utilizing a Population-Genetic Framework to Test for Gene-Environment Interactions between Zebrafish ... | Thunga, Preethi; Truong, Lisa; Rericha, Yvonne; Du, Jane La; Morshead, Mackenzie; Tanguay, Rob ... | P30ES030287, P42ES016465, R01ES033243, T32ES007060 | Toxics (2022 Dec 09) |
36548602
|
2022 |
| What next for eating disorder genetics? Replacing myths with facts to sharpen our understanding. | Huckins, Laura M; Signer, Rebecca; Johnson, Jessica; Wu, Ya-Ke; Mitchell, Karen S; Bulik, Cynt ... | R01ES033630 | Mol Psychiatry (2022 Oct) |
35595976
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2022 |
| A model and test for coordinated polygenic epistasis in complex traits. | Sheppard, Brooke; Rappoport, Nadav; Loh, Po-Ru; Sanders, Stephan J; Zaitlen, Noah; Dahl, Andy | R01ES029929 | Proc Natl Acad Sci U S A (2021 Apr 13) |
33833052
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2021 |
| A polygenic-score-based approach for identification of gene-drug interactions stratifying breast can ... | Marderstein, Andrew R; Kulm, Scott; Peng, Cheng; Tamimi, Rulla; Clark, Andrew G; Elemento, Oli ... | R01ES029929 | Am J Hum Genet (2021 Sep 02) |
34363748
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2021 |
| An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα wit ... | Hammel, Michal; Rashid, Ishtiaque; Sverzhinsky, Aleksandr; Pourfarjam, Yasin; Tsai, Miaw-Sheue; ... | R01ES012512 | Nucleic Acids Res (2021 01 11) |
33330937
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2021 |
| Asbestos-induced chronic inflammation in malignant pleural mesothelioma and related therapeutic appr ... | Zolondick, Alicia A; Gaudino, Giovanni; Xue, Jiaming; Pass, Harvey I; Carbone, Michele; Yang, ... | R01ES030948 | Precis Cancer Med (2021 Sep) |
35098108
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2021 |
| Balancing selection maintains hyper-divergent haplotypes in Caenorhabditis elegans. | Lee, Daehan; Zdraljevic, Stefan; Stevens, Lewis; Wang, Ye; Tanny, Robyn E; Crombie, Timothy A; ... | R01ES029930 | Nat Ecol Evol (2021 Jun) |
33820969
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2021 |
| BAP1 forms a trimer with HMGB1 and HDAC1 that modulates gene × environment interaction with asbestos ... | Novelli, Flavia; Bononi, Angela; Wang, Qian; Bai, Fang; Patergnani, Simone; Kricek, Franz; Hag ... | R01ES030948 | Proc Natl Acad Sci U S A (2021 Nov 30) |
34815344
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2021 |
| CCmed: cross-condition mediation analysis for identifying replicable trans-associations mediated by ... | Yang, Fan; Gleason, Kevin J; Wang, Jiebiao; Duan, Jubao; He, Xin; Pierce, Brandon L; Chen, Li ... | R35ES028379 | Bioinformatics (2021 Sep 09) |
33647928
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2021 |
| Comprehensive cell type decomposition of circulating cell-free DNA with CelFiE. | Caggiano, Christa; Celona, Barbara; Garton, Fleur; Mefford, Joel; Black, Brian L; Henderson, R ... | R01ES029929 | Nat Commun (2021 05 11) |
33976150
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2021 |
| Constructing germline research cohorts from the discarded reads of clinical tumor sequences. | Gusev, Alexander; Groha, Stefan; Taraszka, Kodi; Semenov, Yevgeniy R; Zaitlen, Noah | R01ES029929 | Genome Med (2021 11 08) |
34749793
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2021 |
| Coronavirus 2019 Infectious Disease Epidemic: Where We Are, What Can Be Done and Hope For. | Carbone, Michele; Lednicky, John; Xiao, Shu-Yuan; Venditti, Mario; Bucci, Enrico | R01ES030948 | J Thorac Oncol (2021 Apr) |
33422679
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2021 |
| Design and analysis of CRISPR-based underdominance toxin-antidote gene drives. | Champer, Jackson; Champer, Samuel E; Kim, Isabel K; Clark, Andrew G; Messer, Philipp W | R01ES029929 | Evol Appl (2021 Apr) |
33897820
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2021 |
| Direct interaction of DNA repair protein tyrosyl DNA phosphodiesterase 1 and the DNA ligase III cata ... | Rashid, Ishtiaque; Hammel, Michal; Sverzhinsky, Aleksandr; Tsai, Miaw-Sheue; Pascal, John M; Ta ... | R01ES012512 | J Biol Chem (2021 08) |
34181949
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2021 |
| Disentangling selection on genetically correlated polygenic traits via whole-genome genealogies. | Stern, Aaron J; Speidel, Leo; Zaitlen, Noah A; Nielsen, Rasmus | R01ES029929 | Am J Hum Genet (2021 Feb 04) |
33440170
|
2021 |
| easyXpress: An R package to analyze and visualize high-throughput C. elegans microscopy data generat ... | Nyaanga, Joy; Crombie, Timothy A; Widmayer, Samuel J; Andersen, Erik C | R01ES029930 | PLoS One (2021) |
34383778
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2021 |
| Effects of GSTT1 Genotype on the Detoxification of 1,3-Butadiene Derived Diepoxide and Formation of ... | Boysen, Gunnar; Arora, Rashi; Degner, Amanda; Vevang, Karin R; Chao, Christopher; Rodriguez, F ... | R01ES029911 | Chem Res Toxicol (2021 01 18) |
33381973
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2021 |
| Erratum: "Rare, protein-altering variants in AS3MT and arsenic metabolism efficiency: a multi-popula ... | Delgado, Dayana A; Chernoff, Meytal; Huang, Lei; Tong, Lin; Chen, Lin; Jasmine, Farzana; Shink ... | R35ES028379 | Environ Health Perspect (2021 May) |
34038222
|
2021 |
| From QTL to gene: C. elegans facilitates discoveries of the genetic mechanisms underlying natural va ... | Evans, Kathryn S; van Wijk, Marijke H; McGrath, Patrick T; Andersen, Erik C; Sterken, Mark G | R01ES029930 | Trends Genet (2021 10) |
34229867
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2021 |
| Genetically Increased Telomere Length and Aging-Related Traits in the U.K. Biobank. | Demanelis, Kathryn; Tong, Lin; Pierce, Brandon L | R35ES028379 | J Gerontol A Biol Sci Med Sci (2021 01 01) |
31603979
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2021 |
| HMGB1 as a therapeutic target in disease. | Xue, Jiaming; Suarez, Joelle S; Minaai, Michael; Li, Shuangjing; Gaudino, Giovanni; Pass, Harv ... | R01ES030948 | J Cell Physiol (2021 05) |
33107103
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2021 |
| Intra- and Inter-Species Variability in Urinary N7-(1-Hydroxy-3-buten-2-yl)guanine Adducts Following ... | Erber, Luke; Goodman, Samantha; Wright, Fred A; Chiu, Weihsueh A; Tretyakova, Natalia Y; Rusyn, ... | R01ES029911, T32ES026568 | Chem Res Toxicol (2021 Nov 15) |
34726909
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2021 |
| Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores tha ... | Võsa, Urmo; Claringbould, Annique; Westra, Harm-Jan; Bonder, Marc Jan; Deelen, Patrick; Zeng, ... | R35ES028379 | Nat Genet (2021 Sep) |
34475573
|
2021 |
| Ligase 1 is a predictor of platinum resistance and its blockade is synthetically lethal in XRCC1 def ... | Ali, Reem; Alabdullah, Muslim; Algethami, Mashael; Alblihy, Adel; Miligy, Islam; Shoqafi, Ahme ... | R01ES012512 | Theranostics (2021) |
34373746
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2021 |
| Meta-analysis suggests the microbiome responds to Evolve and Resequence experiments in Drosophila me ... | Henry, Lucas P; Ayroles, Julien F | R01ES029929 | BMC Microbiol (2021 Apr 09) |
33836662
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2021 |
| Mouse Genetic Reference Populations: Cellular Platforms for Integrative Systems Genetics. | Swanzey, Emily; O'Connor, Callan; Reinholdt, Laura G | R01ES029916 | Trends Genet (2021 Mar) |
33010949
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2021 |
| Proteome-Wide Profiling of Cellular Targets Modified by Dopamine Metabolites Using a Bio-Orthogonall ... | Hurben, Alexander K; Erber, Luke N; Tretyakova, Natalia Y; Doran, Todd M | R01ES023350, R01ES029911 | ACS Chem Biol (2021 Nov 19) |
34726906
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2021 |
| Quantitative NanoLC/NSI+-HRMS Method for 1,3-Butadiene Induced bis-N7-guanine DNA-DNA Cross-Links in ... | Erber, Luke; Goodman, Samantha; Jokipii Krueger, Caitlin C; Rusyn, Ivan; Tretyakova, Natalia | R01ES029911, T32ES026568 | Toxics (2021 Oct 02) |
34678943
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2021 |
| Selfing is the safest sex for Caenorhabditis tropicalis. | Noble, Luke M; Yuen, John; Stevens, Lewis; Moya, Nicolas; Persaud, Riaad; Moscatelli, Marc; Ja ... | R01ES029930 | Elife (2021 Jan 11) |
33427200
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2021 |
| Suppression gene drive in continuous space can result in unstable persistence of both drive and wild ... | Champer, Jackson; Kim, Isabel K; Champer, Samuel E; Clark, Andrew G; Messer, Philipp W | R01ES029929 | Mol Ecol (2021 02) |
33404162
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2021 |
| Xenobiotic metabolism and transport in Caenorhabditis elegans. | Hartman, Jessica H; Widmayer, Samuel J; Bergemann, Christina M; King, Dillon E; Morton, Katheri ... | P42ES010356, R01ES029930, T32ES021432 | J Toxicol Environ Health B Crit Rev (2021 Feb 17) |
33616007
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2021 |
| A CRISPR homing gene drive targeting a haplolethal gene removes resistance alleles and successfully ... | Champer, Jackson; Yang, Emily; Lee, Esther; Liu, Jingxian; Clark, Andrew G; Messer, Philipp W | R01ES029929 | Proc Natl Acad Sci U S A (2020 Sep 29) |
32929034
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2020 |
| A Robust Method Uncovers Significant Context-Specific Heritability in Diverse Complex Traits. | Dahl, Andy; Nguyen, Khiem; Cai, Na; Gandal, Michael J; Flint, Jonathan; Zaitlen, Noah | R01ES029929 | Am J Hum Genet (2020 Jan 02) |
31901249
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2020 |
| Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy. | Xue, Jiaming; Patergnani, Simone; Giorgi, Carlotta; Suarez, Joelle; Goto, Keisuke; Bononi, Ang ... | R01ES030948 | Proc Natl Acad Sci U S A (2020 10 13) |
32999071
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2020 |
| Assessing the impact of arsenic metabolism efficiency on DNA methylation using Mendelian randomizati ... | DiGiovanni, Anthony; Demanelis, Kathryn; Tong, Lin; Argos, Maria; Shinkle, Justin; Jasmine, Fa ... | P30ES009089, R35ES028379 | Environ Epidemiol (2020 Apr) |
32337471
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2020 |
| Biological Mechanisms and Clinical Significance of BAP1 Mutations in Human Cancer. | Carbone, Michele; Harbour, J William; Brugarolas, James; Bononi, Angela; Pagano, Ian; Dey, Anw ... | R01ES030948 | Cancer Discov (2020 Aug) |
32690542
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2020 |
| Computational and experimental performance of CRISPR homing gene drive strategies with multiplexed g ... | Champer, Samuel E; Oh, Suh Yeon; Liu, Chen; Wen, Zhaoxin; Clark, Andrew G; Messer, Philipp W; ... | R01ES029929 | Sci Adv (2020 Mar) |
32181354
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2020 |
| Determinants of telomere length across human tissues. | Demanelis, Kathryn; Jasmine, Farzana; Chen, Lin S; Chernoff, Meytal; Tong, Lin; Delgado, Dayan ... | R35ES028379 | Science (2020 09 11) |
32913074
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2020 |
| Efficient Estimation and Applications of Cross-Validated Genetic Predictions to Polygenic Risk Score ... | Mefford, Joel; Park, Danny; Zheng, Zhili; Ko, Arthur; Ala-Korpela, Mika; Laakso, Markku; Pajuk ... | R01ES029929 | J Comput Biol (2020 04) |
32077750
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2020 |
| Genetic Determinants of Reduced Arsenic Metabolism Efficiency in the 10q24.32 Region Are Associated ... | Chernoff, Meytal; Tong, Lin; Demanelis, Kathryn; Vander Griend, Donald; Ahsan, Habib; Pierce, ... | R35ES028379 | Toxicol Sci (2020 08 01) |
32433756
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2020 |
| Heterozygous germline BLM mutations increase susceptibility to asbestos and mesothelioma. | Bononi, Angela; Goto, Keisuke; Ak, Guntulu; Yoshikawa, Yoshie; Emi, Mitsuru; Pastorino, Sandra ... | R01ES030948 | Proc Natl Acad Sci U S A (2020 Dec 29) |
33318203
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2020 |
| Human DNA ligases in replication and repair. | Sallmyr, Annahita; Rashid, Ishtiaque; Bhandari, Seema Khattri; Naila, Tasmin; Tomkinson, Alan E | R01ES012512 | DNA Repair (Amst) (2020 09) |
33087274
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2020 |
| Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patt ... | Keele, Gregory R; Quach, Bryan C; Israel, Jennifer W; Chappell, Grace A; Lewis, Lauren; Safi, ... | P30ES010126, P30ES025128, R01ES029911 | PLoS Genet (2020 Jan) |
31961859
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2020 |
| Interindividual Differences in DNA Adduct Formation and Detoxification of 1,3-Butadiene-Derived Epox ... | Degner, Amanda; Arora, Rashi; Erber, Luke; Chao, Christopher; Peterson, Lisa A; Tretyakova, Na ... | R01ES029911 | Chem Res Toxicol (2020 07 20) |
32237725
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2020 |
| Massively parallel techniques for cataloguing the regulome of the human brain. | Townsley, Kayla G; Brennand, Kristen J; Huckins, Laura M | R01ES033630 | Nat Neurosci (2020 Dec) |
33199899
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2020 |
| Modeling epistasis in mice and yeast using the proportion of two or more distinct genetic background ... | Rau, Christoph D; Gonzales, Natalia M; Bloom, Joshua S; Park, Danny; Ayroles, Julien; Palmer, ... | R01ES029929 | PLoS Genet (2020 10) |
33104702
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2020 |
| Natural variation in the sequestosome-related gene, sqst-5, underlies zinc homeostasis in Caenorhabd ... | Evans, Kathryn S; Zdraljevic, Stefan; Stevens, Lewis; Collins, Kimberly; Tanny, Robyn E; Anders ... | R01ES029930 | PLoS Genet (2020 11) |
33175833
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2020 |
| Primo: integration of multiple GWAS and omics QTL summary statistics for elucidation of molecular me ... | Gleason, Kevin J; Yang, Fan; Pierce, Brandon L; He, Xin; Chen, Lin S | R35ES028379 | Genome Biol (2020 Sep 11) |
32912334
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2020 |
| Research Participants' Attitudes towards Receiving Information on Genetic Susceptibility to Arsenic ... | Tamayo, Lizeth I; Lin, Hannah; Ahmed, Alauddin; Shahriar, Hasan; Hasan, Rabiul; Sarwar, Golam; ... | R35ES028379 | Public Health Genomics (2020) |
32069464
|
2020 |
| The cadmium-responsive gene, cdr-6, does not influence Caenorhabditis elegans responses to exogenous ... | Evans, Kathryn S; Andersen, Erik C | R01ES029930 | MicroPubl Biol (2020 Sep 14) |
33005884
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2020 |
| The Evolution of Variance Control. | Bruijning, Marjolein; Metcalf, C Jessica E; Jongejans, Eelke; Ayroles, Julien F | R01ES029929 | Trends Ecol Evol (2020 Jan) |
31519463
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2020 |
| The Gene scb-1 Underlies Variation in Caenorhabditis elegans Chemotherapeutic Responses. | Evans, Kathryn S; Andersen, Erik C | R01ES029930 | G3 (Bethesda) (2020 07 07) |
32385045
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2020 |
| TM3'seq: A Tagmentation-Mediated 3' Sequencing Approach for Improving Scalability of RNAseq Experime ... | Pallares, Luisa F; Picard, Serge; Ayroles, Julien F | R01ES029929 | G3 (Bethesda) (2020 01 07) |
31676507
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2020 |
| Tumour predisposition and cancer syndromes as models to study gene-environment interactions. | Carbone, Michele; Arron, Sarah T; Beutler, Bruce; Bononi, Angela; Cavenee, Webster; Cleaver, J ... | R01ES030948 | Nat Rev Cancer (2020 Sep) |
32472073
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2020 |
| Using Genetic and Species Diversity to Tackle Kidney Disease. | Garrett, Michael R; Korstanje, Ron | R01ES029916 | Trends Genet (2020 07) |
32362446
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2020 |
| 1HN, 13C, and 15N backbone resonance assignments of the human DNA ligase 3 DNA-binding domain (resid ... | Roth, Braden M; Varney, Kristen M; Yang, Hui; Weber, David J; Tomkinson, Alan E | R01ES012512 | Biomol NMR Assign (2019 10) |
31093909
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2019 |
| 1HN, 13C, and 15N resonance assignments of human calmodulin bound to a peptide derived from the STRA ... | Varney, Kristen M; Wilder, Paul T; Godoy-Ruiz, Raquel; Mancia, Filippo; Weber, David J | R01ES012512 | Biomol NMR Assign (2019 10) |
30875027
|
2019 |
| A missense variant in FTCD is associated with arsenic metabolism and toxicity phenotypes in Banglade ... | Pierce, Brandon L; Tong, Lin; Dean, Samantha; Argos, Maria; Jasmine, Farzana; Rakibuz-Zaman, M ... | P30ES009089, R35ES028379 | PLoS Genet (2019 Mar) |
30893314
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2019 |
| A Novel Gene Underlies Bleomycin-Response Variation in Caenorhabditis elegans. | Brady, Shannon C; Zdraljevic, Stefan; Bisaga, Karol W; Tanny, Robyn E; Cook, Daniel E; Lee, Da ... | R01ES029930 | Genetics (2019 Aug) |
31171655
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2019 |
| Association of Arsenic Exposure with Whole Blood DNA Methylation: An Epigenome-Wide Study of Banglad ... | Demanelis, Kathryn; Argos, Maria; Tong, Lin; Shinkle, Justin; Sabarinathan, Mekala; Rakibuz-Zam ... | P30ES009089, R35ES028379 | Environ Health Perspect (2019 May) |
31135185
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2019 |
| Genetic and environmental perturbations lead to regulatory decoherence. | Lea, Amanda; Subramaniam, Meena; Ko, Arthur; Lehtimäki, Terho; Raitoharju, Emma; Kähönen, Mika ... | R01ES029929 | Elife (2019 Mar 05) |
30834892
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2019 |
| Natural variation in C. elegans arsenic toxicity is explained by differences in branched chain amino ... | Zdraljevic, Stefan; Fox, Bennett William; Strand, Christine; Panda, Oishika; Tenjo, Francisco J ... | R01ES029930 | Elife (2019 04 08) |
30958264
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2019 |
| Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the Mouse. | Lewis, Lauren; Borowa-Mazgaj, Barbara; de Conti, Aline; Chappell, Grace A; Luo, Yu-Syuan; Bodna ... | R01ES029911 | Chem Res Toxicol (2019 05 20) |
30990016
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2019 |
| Sex-specific differences in genotoxic and epigenetic effects of 1,3-butadiene among mouse tissues. | Lewis, Lauren; Chappell, Grace A; Kobets, Tetyana; O'Brian, Bridget E; Sangaraju, Dewakar; Kosy ... | P30ES025128, P30ES029067, R01ES029911 | Arch Toxicol (2019 Mar) |
30552462
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2019 |
| SUMOning the base excision repair machinery for differentiation. | Wiest, Nathaniel E; Tomkinson, Alan E | R01ES012512 | EMBO J (2019 01 03) |
30545824
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2019 |
| The contribution of parent-to-offspring transmission of telomeres to the heritability of telomere le ... | Delgado, Dayana A; Zhang, Chenan; Gleason, Kevin; Demanelis, Kathryn; Chen, Lin S; Gao, Jianju ... | R35ES028379 | Hum Genet (2019 Jan) |
30536049
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2019 |
| The effect of age on DNA methylation in whole blood among Bangladeshi men and women. | Jansen, Rick J; Tong, Lin; Argos, Maria; Jasmine, Farzana; Rakibuz-Zaman, Muhammad; Sarwar, Go ... | R35ES028379 | BMC Genomics (2019 Sep 10) |
31506065
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2019 |
| Tightly linked antagonistic-effect loci underlie polygenic phenotypic variation in C. elegans. | Bernstein, Max R; Zdraljevic, Stefan; Andersen, Erik C; Rockman, Matthew V | R01ES029930 | Evol Lett (2019 Oct) |
31636939
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2019 |
| Using Collaborative Cross Mouse Population to Fill Data Gaps in Risk Assessment: A Case Study of Pop ... | Luo, Yu-Syuan; Cichocki, Joseph A; Hsieh, Nan-Hung; Lewis, Lauren; Wright, Fred A; Threadgill, ... | P30ES029067, P42ES027704, P42ES027704, R01ES029911 | Environ Health Perspect (2019 06) |
31246107
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2019 |
| A novel pooled-sample multiplex luminex assay for high-throughput measurement of relative telomere l ... | Jasmine, Farzana; Shinkle, Justin; Sabarinathan, Mekala; Ahsan, Habibul; Pierce, Brandon L; Kib ... | R35ES028379 | Am J Hum Biol (2018 Jul) |
29527774
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2018 |
| A study of telomere length, arsenic exposure, and arsenic toxicity in a Bangladeshi cohort. | Zhang, Chenan; Kibriya, Muhammad G; Jasmine, Farzana; Roy, Shantanu; Gao, Jianjun; Sabarinathan ... | R35ES028379 | Environ Res (2018 07) |
29567420
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2018 |
| Co-occurring expression and methylation QTLs allow detection of common causal variants and shared bi ... | Pierce, Brandon L; Tong, Lin; Argos, Maria; Demanelis, Kathryn; Jasmine, Farzana; Rakibuz-Zaman ... | R35ES028379 | Nat Commun (2018 Feb 23) |
29476079
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2018 |
| Genome-wide association study of telomere length among South Asians identifies a second RTEL1 associ ... | Delgado, Dayana A; Zhang, Chenan; Chen, Lin S; Gao, Jianjun; Roy, Shantanu; Shinkle, Justin; S ... | R35ES028379 | J Med Genet (2018 01) |
29151059
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2018 |
| Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Scl ... | Wang, Haibo; Guo, Wenting; Mitra, Joy; Hegde, Pavana M; Vandoorne, Tijs; Eckelmann, Bradley J; ... | R01ES012512 | Nat Commun (2018 Sep 11) |
30206235
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2018 |
| Repair of DNA double-strand breaks by mammalian alternative end-joining pathways. | Sallmyr, Annahita; Tomkinson, Alan E | R01ES012512 | J Biol Chem (2018 07 06) |
29530982
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2018 |
| Screening for gene-environment (G×E) interaction using omics data from exposed individuals: an appli ... | Argos, Maria; Tong, Lin; Roy, Shantanu; Sabarinathan, Mekala; Ahmed, Alauddin; Islam, Md Tariq ... | P30ES009089, R35ES028379 | Mamm Genome (2018 Feb) |
29453499
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2018 |
| Incorporation of Biological Knowledge Into the Study of Gene-Environment Interactions. | Ritchie, Marylyn D; Davis, Joe R; Aschard, Hugues; Battle, Alexis; Conti, David; Du, Mengmeng; ... | P30ES007048, P30ES013508, R35ES028379 | Am J Epidemiol (2017 Oct 01) |
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2017 |
| Lessons Learned From Past Gene-Environment Interaction Successes. | Ritz, Beate R; Chatterjee, Nilanjan; Garcia-Closas, Montserrat; Gauderman, W James; Pierce, Bra ... | P30ES007048, R35ES028379 | Am J Epidemiol (2017 Oct 01) |
28978190
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2017 |
| Optimization of Native and Formaldehyde iPOND Techniques for Use in Suspension Cells. | Wiest, Nathaniel E; Tomkinson, Alan E | R01ES012512 | Methods Enzymol (2017) |
28645366
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2017 |
| Structure-activity relationships among DNA ligase inhibitors: Characterization of a selective uncomp ... | Howes, Timothy R L; Sallmyr, Annahita; Brooks, Rhys; Greco, George E; Jones, Darin E; Matsumoto ... | R01ES012512 | DNA Repair (Amst) (2017 Dec) |
29078112
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2017 |
| The association between telomere length and mortality in Bangladesh. | Dean, Samantha G; Zhang, Chenan; Gao, Jianjun; Roy, Shantanu; Shinkle, Justin; Sabarinathan, M ... | R35ES028379 | Aging (Albany NY) (2017 Jun 15) |
28630379
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2017 |
| The Human Ligase IIIα-XRCC1 Protein Complex Performs DNA Nick Repair after Transient Unwrapping of N ... | Cannan, Wendy J; Rashid, Ishtiaque; Tomkinson, Alan E; Wallace, Susan S; Pederson, David S | R01ES012512 | J Biol Chem (2017 Mar 31) |
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2017 |
| Inhibiting Mitochondrial DNA Ligase IIIα Activates Caspase 1-Dependent Apoptosis in Cancer Cells. | Sallmyr, Annahita; Matsumoto, Yoshihiro; Roginskaya, Vera; Van Houten, Bennett; Tomkinson, Alan ... | R01ES012512 | Cancer Res (2016 Sep 15) |
27503931
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2016 |
| SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV. | Greco, George E; Matsumoto, Yoshihiro; Brooks, Rhys C; Lu, Zhengfei; Lieber, Michael R; Tomkins ... | R01ES012512 | DNA Repair (Amst) (2016 07) |
27235626
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2016 |
| Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining. | Kukshal, Vandna; Kim, In-Kwon; Hura, Gregory L; Tomkinson, Alan E; Tainer, John A; Ellenberger, ... | R01ES012512 | Nucleic Acids Res (2015 Aug 18) |
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2015 |
| Chromosomal translocations in human cells are generated by canonical nonhomologous end-joining. | Ghezraoui, Hind; Piganeau, Marion; Renouf, Benjamin; Renaud, Jean-Baptiste; Sallmyr, Annahita; ... | R01ES012512 | Mol Cell (2014 Sep 18) |
25201414
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2014 |
| DNA ligases as therapeutic targets. | Tomkinson, Alan E; Howes, Timothy R L; Wiest, Nathaniel E | R01ES012512 | Transl Cancer Res (2013 Jun) |
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2013 |
| Structure and function of the DNA ligases encoded by the mammalian LIG3 gene. | Tomkinson, Alan E; Sallmyr, Annahita | R01ES012512 | Gene (2013 Dec 01) |
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2013 |
| Targeting abnormal DNA double-strand break repair in tyrosine kinase inhibitor-resistant chronic mye ... | Tobin, L A; Robert, C; Rapoport, A P; Gojo, I; Baer, M R; Tomkinson, A E; Rassool, F V | R01ES012512 | Oncogene (2013 Apr 04) |
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2013 |
| Increased risk of lung cancer associated with a functionally impaired polymorphic variant of the hum ... | Dey, Sanjib; Maiti, Amit K; Hegde, Muralidhar L; Hegde, Pavana M; Boldogh, Istvan; Sarkar, Par ... | R01ES012512 | DNA Repair (Amst) (2012 Jun 01) |
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2012 |
| Targeting abnormal DNA repair in therapy-resistant breast cancers. | Tobin, Lisa A; Robert, Carine; Nagaria, Pratik; Chumsri, Saranya; Twaddell, William; Ioffe, Ol ... | R01ES012512 | Mol Cancer Res (2012 Jan) |
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2012 |
| The interaction between polynucleotide kinase phosphatase and the DNA repair protein XRCC1 is critic ... | Della-Maria, Julie; Hegde, Muralidhar L; McNeill, Daniel R; Matsumoto, Yoshihiro; Tsai, Miaw-Sh ... | R01ES012512 | J Biol Chem (2012 Nov 09) |
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2012 |
| The nucleotide sequence, DNA damage location, and protein stoichiometry influence the base excision ... | Goula, Agathi-Vasiliki; Pearson, Christopher E; Della Maria, Julie; Trottier, Yvon; Tomkinson, ... | R01ES012512 | Biochemistry (2012 May 8) |
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2012 |
| Human Mre11/human Rad50/Nbs1 and DNA ligase IIIalpha/XRCC1 protein complexes act together in an alte ... | Della-Maria, Julie; Zhou, Yi; Tsai, Miaw-Sheue; Kuhnlein, Jeff; Carney, James P; Paull, Tanya ... | R01ES012512 | J Biol Chem (2011 Sep 30) |
21816818
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2011 |
| Nucleosome disruption by DNA ligase III-XRCC1 promotes efficient base excision repair. | Odell, Ian D; Barbour, Joy-El; Murphy, Drew L; Della-Maria, Julie A; Sweasy, Joann B; Tomkinson ... | R01ES012512 | Mol Cell Biol (2011 Nov) |
21930793
|
2011 |
| Replication protein A safeguards genome integrity by controlling NER incision events. | Overmeer, René M; Moser, Jill; Volker, Marcel; Kool, Hanneke; Tomkinson, Alan E; van Zeeland, ... | R01ES012512 | J Cell Biol (2011 Feb 07) |
21282463
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2011 |
| Functional capacity of XRCC1 protein variants identified in DNA repair-deficient Chinese hamster ova ... | Berquist, Brian R; Singh, Dharmendra Kumar; Fan, Jinshui; Kim, Daemyung; Gillenwater, Elizabeth ... | R01ES012512 | Nucleic Acids Res (2010 Aug) |
20385586
|
2010 |
| Human DNA ligase III recognizes DNA ends by dynamic switching between two DNA-bound states. | Cotner-Gohara, Elizabeth; Kim, In-Kwon; Hammel, Michal; Tainer, John A; Tomkinson, Alan E; Elle ... | R01ES012512 | Biochemistry (2010 Jul 27) |
20518483
|
2010 |
| Targeting abnormal DNA double strand break repair in cancer. | Rassool, Feyruz V; Tomkinson, Alan E | R01ES012512 | Cell Mol Life Sci (2010 Nov) |
20697770
|
2010 |
| Distinct kinetics of human DNA ligases I, IIIalpha, IIIbeta, and IV reveal direct DNA sensing abilit ... | Chen, Xi; Ballin, Jeff D; Della-Maria, Julie; Tsai, Miaw-Sheue; White, Elizabeth J; Tomkinson, ... | R01ES012512 | DNA Repair (Amst) (2009 Aug 6) |
19589734
|
2009 |
| Eukaryotic DNA ligases: structural and functional insights. | Ellenberger, Tom; Tomkinson, Alan E | R01ES012512 | Annu Rev Biochem (2008) |
18518823
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2008 |
| Identification and validation of human DNA ligase inhibitors using computer-aided drug design. | Zhong, Shijun; Chen, Xi; Zhu, Xiao; Dziegielewska, Barbara; Bachman, Kurtis E; Ellenberger, To ... | R01ES012512 | J Med Chem (2008 Aug 14) |
18630893
|
2008 |
| Rational design of human DNA ligase inhibitors that target cellular DNA replication and repair. | Chen, Xi; Zhong, Shijun; Zhu, Xiao; Dziegielewska, Barbara; Ellenberger, Tom; Wilson, Gerald M ... | R01ES012512 | Cancer Res (2008 May 1) |
18451142
|
2008 |
| Two DNA-binding and nick recognition modules in human DNA ligase III. | Cotner-Gohara, Elizabeth; Kim, In-Kwon; Tomkinson, Alan E; Ellenberger, Tom | R01ES012512 | J Biol Chem (2008 Apr 18) |
18238776
|
2008 |
| Up-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repai ... | Sallmyr, Annahita; Tomkinson, Alan E; Rassool, Feyruz V | R01ES012512 | Blood (2008 Aug 15) |
18524993
|
2008 |
| ATM mediates oxidative stress-induced dephosphorylation of DNA ligase IIIalpha. | Dong, Zhiwan; Tomkinson, Alan E | R01ES012512 | Nucleic Acids Res (2006) |
17040896
|
2006 |
| DNA ligases: structure, reaction mechanism, and function. | Tomkinson, Alan E; Vijayakumar, Sangeetha; Pascal, John M; Ellenberger, Tom | R01ES012512 | Chem Rev (2006 Feb) |
16464020
|
2006 |
| Human DNA ligases I, III, and IV-purification and new specific assays for these enzymes. | Chen, Xi; Pascal, John; Vijayakumar, Sangeetha; Wilson, Gerald M; Ellenberger, Tom; Tomkinson, ... | R01ES012512 | Methods Enzymol (2006) |
16793394
|
2006 |
| NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in h ... | Das, Aditi; Wiederhold, Lee; Leppard, John B; Kedar, Padmini; Prasad, Rajendra; Wang, Huxian; ... | R01ES012512 | DNA Repair (Amst) (2006 Dec 09) |
16982218
|
2006 |
| Translocation of XRCC1 and DNA ligase IIIalpha from centrosomes to chromosomes in response to DNA da ... | Okano, Satoshi; Lan, Li; Tomkinson, Alan E; Yasui, Akira | R01ES012512 | Nucleic Acids Res (2005) |
15653642
|
2005 |