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Your Environment. Your Health.

Who We Fund: Publications associated with Basic Cellular And Molecular Research - Human Genetics / Gene X Environment Interaction

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 122 publications
Export to Excel (http://www.niehs.nih.gov//portfolio/index.cfm?do=portfolio.sciencecodepubs&&sc=07&topic=7&format=excel)
Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
A Population-Based Human In Vitro Approach to Quantify Inter-Individual Variability in Responses to ...   Ford, Lucie C; Jang, Suji; Chen, Zunwei; Zhou, Yi-Hui; Gallins, Paul J; Wright, Fred A; Chiu, ... P42ES027704, R01ES029911, T32ES026568 Toxics (2022 Aug 01) 36006120 Exiting the NIEHS site 2022 
A resource for integrated genomic analysis of the human liver.   Zhou, Yi-Hui; Gallins, Paul J; Etheridge, Amy S; Jima, Dereje; Scholl, Elizabeth; Wright, Fred ... P42ES027704, R01ES029911 Sci Rep (2022 Sep 07) 36071064 Exiting the NIEHS site 2022 
An interaction of inorganic arsenic exposure with body weight and composition on type 2 diabetes ind ...   Xenakis, James G; Douillet, Christelle; Bell, Timothy A; Hock, Pablo; Farrington, Joseph; Liu, ... P42ES031007, R01ES028721, R01ES028721, R01ES029925, T32ES007126 Mamm Genome (2022 Jul 11) 35819478 Exiting the NIEHS site 2022 
Characterization of population variability of 1,3-butadiene derived protein adducts in humans and mi ...   Boysen, Gunnar; Rusyn, Ivan; Chiu, Weihsueh A; Wright, Fred A P30ES029067, P42ES027704, R01ES029911 Regul Toxicol Pharmacol (2022 Jul) 35469930 Exiting the NIEHS site 2022 
Chromosome-Level Genome Assembly of the Bioluminescent Cardinalfish Siphamia tubifer: An Emerging Mo ...   Gould, A L; Henderson, J B; Lam, A W R01ES029930 Genome Biol Evol (2022 04 10) 35349687 Exiting the NIEHS site 2022 
Chromosome-Level Reference Genomes for Two Strains of Caenorhabditis briggsae: An Improved Platform ...   Stevens, Lewis; Moya, Nicolas D; Tanny, Robyn E; Gibson, Sophia B; Tracey, Alan; Na, Huimin; C ... R01ES029930 Genome Biol Evol (2022 04 10) 35348662 Exiting the NIEHS site 2022 
Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogen ...   Goodman, Samantha; Chappell, Grace; Guyton, Kathryn Z; Pogribny, Igor P; Rusyn, Ivan R01ES029911, T32ES026568 Mutat Res Rev Mutat Res (2022 Jan-Jun) 35690411 Exiting the NIEHS site 2022 
Evaluating the power and limitations of genome-wide association studies in Caenorhabditis elegans.   Widmayer, Samuel J; Evans, Kathryn S; Zdraljevic, Stefan; Andersen, Erik C R01ES029930 G3 (Bethesda) (2022 Jul 06) 35536194 Exiting the NIEHS site 2022 
Exploring the clinical and genetic associations of adult weight trajectories using electronic health ...   Xu, Jiayi; Johnson, Jessica S; Signer, Rebecca; Eating Disorders Working Group of the Psychiatric ... R01ES033630 Lancet Digit Health (2022 08) 35780037 Exiting the NIEHS site 2022 
Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fa ...   Nagumalli, Suresh K; Willett, Rose A; de Conti, Aline; Tryndyak, Volodymyr P; Avigan, Mark I; d ... R01ES029911 J Nutr Biochem (2022 Jul 17) 35858665 Exiting the NIEHS site 2022 
Massively parallel analysis of human 3' UTRs reveals that AU-rich element length and registration pr ...   Siegel, David A; Le Tonqueze, Olivier; Biton, Anne; Zaitlen, Noah; Erle, David J R01ES029929 G3 (Bethesda) (2022 01 04) 34849835 Exiting the NIEHS site 2022 
Medical and Surgical Care of Patients With Mesothelioma and Their Relatives Carrying Germline BAP1 M ...   Carbone, Michele; Pass, Harvey I; Ak, Guntulu; Alexander Jr, H Richard; Baas, Paul; Baumann, F ... R01ES030948 J Thorac Oncol (2022 07) 35462085 Exiting the NIEHS site 2022 
Methylation risk scores are associated with a collection of phenotypes within electronic health reco ...   Thompson, Mike; Hill, Brian L; Rakocz, Nadav; Chiang, Jeffrey N; Geschwind, Daniel; Sankararama ... R01ES029929 NPJ Genom Med (2022 Aug 25) 36008412 Exiting the NIEHS site 2022 
Model systems and organisms for addressing inter- and intra-species variability in risk assessment.   Rusyn, Ivan; Chiu, Weihsueh A; Wright, Fred A P30ES029067, P42ES027704, R01ES029911 Regul Toxicol Pharmacol (2022 Jul) 35636685 Exiting the NIEHS site 2022 
Natural genetic variation as a tool for discovery in Caenorhabditis nematodes.   Andersen, Erik C; Rockman, Matthew V R01ES029930, R21ES031364 Genetics (2022 01 04) 35134197 Exiting the NIEHS site 2022 
Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the ...   Tryndyak, Volodymyr P; Willett, Rose A; Avigan, Mark I; Sanyal, Arun J; Beland, Frederick A; Ru ... R01ES029911 Epigenetics (2022 Mar 24) 35324388 Exiting the NIEHS site 2022 
Powerful, efficient QTL mapping in Drosophila melanogaster using bulked phenotyping and pooled seque ...   Macdonald, Stuart J; Cloud-Richardson, Kristen M; Sims-West, Dylan J; Long, Anthony D R01ES029922 Genetics (2022 03 03) 35100395 Exiting the NIEHS site 2022 
Relative Telomere Length Change in Colorectal Carcinoma and Its Association with Tumor Characteristi ...   Kibriya, Muhammad G; Raza, Maruf; Kamal, Mohammed; Haq, Zahidul; Paul, Rupash; Mareczko, Andre ... R35ES028379 Cancers (Basel) (2022 Apr 30) 35565379 Exiting the NIEHS site 2022 
Serum concentrations of legacy and emerging per- and polyfluoroalkyl substances in the Anniston Comm ...   Petriello, Michael C; Mottaleb, M Abdul; Serio, Tara C; Balyan, Bharat; Cave, Matthew C; Pavuk, ... P30ES020957, P30ES026529, P30ES030283, P42ES007380, P42ES023716, R00ES028734, R00ES028734, R35ES028379 Environ Int (2022 01) 34763231 Exiting the NIEHS site 2022 
The aryl hydrocarbon receptor: A predominant mediator for the toxicity of emerging dioxin-like compo ...   Zhang, Wanglong; Xie, Heidi Qunhui; Li, Yunping; Zhou, Mingxi; Zhou, Zhiguang; Wang, Renjun; H ... R01ES032323 J Hazard Mater (2022 03 15) 34952507 Exiting the NIEHS site 2022 
The impact of genetic background on mouse models of kidney disease.   Bufi, Rei; Korstanje, Ron R01ES029916 Kidney Int (2022 07) 35429495 Exiting the NIEHS site 2022 
The pharmacokinetics of therapeutic arsenic trioxide in acute promyelocytic leukemia patients.   Ghiuzeli, Cristina M; Stýblo, Miroslav; Saunders, Jesse; Calabro, Anthony; Budman, Daniel; Alle ... P42ES031007, R01ES029925, R01ES032643, R01ES032643 Leuk Lymphoma (2022 03) 34689693 Exiting the NIEHS site 2022 
Using population selection and sequencing to characterize natural variation of starvation resistance ...   Webster, Amy K; Chitrakar, Rojin; Powell, Maya; Chen, Jingxian; Fisher, Kinsey; Tanny, Robyn E ... R01ES029930 Elife (2022 06 21) 35727141 Exiting the NIEHS site 2022 
What next for eating disorder genetics? Replacing myths with facts to sharpen our understanding.   Huckins, Laura M; Signer, Rebecca; Johnson, Jessica; Wu, Ya-Ke; Mitchell, Karen S; Bulik, Cynt ... R01ES033630 Mol Psychiatry (2022 May 20) 35595976 Exiting the NIEHS site 2022 
A model and test for coordinated polygenic epistasis in complex traits.   Sheppard, Brooke; Rappoport, Nadav; Loh, Po-Ru; Sanders, Stephan J; Zaitlen, Noah; Dahl, Andy R01ES029929 Proc Natl Acad Sci U S A (2021 04 13) 33833052 Exiting the NIEHS site 2021 
A Murine Model of Ozone-induced Nonatopic Asthma from the Collaborative Cross.   Smith, Gregory J; Tovar, Adelaide; McFadden, Kathryn; Moran, Timothy P; Wagner, James G; Harkem ... R21ES032089, T32ES007126 Am J Respir Cell Mol Biol (2021 12) 34851239 Exiting the NIEHS site 2021 
A polygenic-score-based approach for identification of gene-drug interactions stratifying breast can ...   Marderstein, Andrew R; Kulm, Scott; Peng, Cheng; Tamimi, Rulla; Clark, Andrew G; Elemento, Oli ... R01ES029929 Am J Hum Genet (2021 09 02) 34363748 Exiting the NIEHS site 2021 
Adverse effects of air pollution-derived fine particulate matter on cardiovascular homeostasis and d ...   Bae, Hye Ryeong; Chandy, Mark; Aguilera, Juan; Smith, Eric M; Nadeau, Kari C; Wu, Joseph C; Pa ... R01ES032253, R01ES032253, R21ES033049 Trends Cardiovasc Med (2021 Oct 05) 34619335 Exiting the NIEHS site 2021 
Asbestos-induced chronic inflammation in malignant pleural mesothelioma and related therapeutic appr ...   Zolondick, Alicia A; Gaudino, Giovanni; Xue, Jiaming; Pass, Harvey I; Carbone, Michele; Yang, ... R01ES030948 Precis Cancer Med (2021 Sep) 35098108 Exiting the NIEHS site 2021 
Associations of Residential Brownness and Greenness with Fasting Glucose in Young Healthy Adults Liv ...   Olvera-Alvarez, Hector A; Browning, Matthew H E M; Neophytou, Andreas M; Bratman, Gregory N R00ES027511, R01ES014639, R01ES014639 Int J Environ Res Public Health (2021 01 10) 33435223 Exiting the NIEHS site 2021 
Balancing selection maintains hyper-divergent haplotypes in Caenorhabditis elegans.   Lee, Daehan; Zdraljevic, Stefan; Stevens, Lewis; Wang, Ye; Tanny, Robyn E; Crombie, Timothy A; ... R01ES029930 Nat Ecol Evol (2021 06) 33820969 Exiting the NIEHS site 2021 
BAP1 forms a trimer with HMGB1 and HDAC1 that modulates gene × environment interaction with asbestos ...   Novelli, Flavia; Bononi, Angela; Wang, Qian; Bai, Fang; Patergnani, Simone; Kricek, Franz; Hag ... R01ES030948 Proc Natl Acad Sci U S A (2021 11 30) 34815344 Exiting the NIEHS site 2021 
CCmed: Cross-condition mediation analysis for identifying replicable trans-associations mediated by ...   Yang, Fan; Gleason, Kevin J; Wang, Jiebiao; Duan, Jubao; He, Xin; Pierce, Brandon L; Chen, Li ... R35ES028379 Bioinformatics (2021 Feb 27) 33647928 Exiting the NIEHS site 2021 
Characterizing the genetic basis of copper toxicity in Drosophila reveals a complex pattern of allel ...   Everman, Elizabeth R; Cloud-Richardson, Kristen M; Macdonald, Stuart J R01ES029922 Genetics (2021 03 03) 33683361 Exiting the NIEHS site 2021 
Comprehensive cell type decomposition of circulating cell-free DNA with CelFiE.   Caggiano, Christa; Celona, Barbara; Garton, Fleur; Mefford, Joel; Black, Brian L; Henderson, R ... R01ES029929 Nat Commun (2021 05 11) 33976150 Exiting the NIEHS site 2021 
Constructing germline research cohorts from the discarded reads of clinical tumor sequences.   Gusev, Alexander; Groha, Stefan; Taraszka, Kodi; Semenov, Yevgeniy R; Zaitlen, Noah R01ES029929 Genome Med (2021 11 08) 34749793 Exiting the NIEHS site 2021 
Coronavirus 2019 Infectious Disease Epidemic: Where We Are, What Can Be Done and Hope For.   Carbone, Michele; Lednicky, John; Xiao, Shu-Yuan; Venditti, Mario; Bucci, Enrico R01ES030948 J Thorac Oncol (2021 04) 33422679 Exiting the NIEHS site 2021 
Design and analysis of CRISPR-based underdominance toxin-antidote gene drives.   Champer, Jackson; Champer, Samuel E; Kim, Isabel K; Clark, Andrew G; Messer, Philipp W R01ES029929 Evol Appl (2021 Apr) 33897820 Exiting the NIEHS site 2021 
Disentangling selection on genetically correlated polygenic traits via whole-genome genealogies.   Stern, Aaron J; Speidel, Leo; Zaitlen, Noah A; Nielsen, Rasmus R01ES029929 Am J Hum Genet (2021 02 04) 33440170 Exiting the NIEHS site 2021 
Diverse genetic backgrounds play a prominent role in the metabolic phenotype of CC021/Unc and CC027/ ...   Douillet, Christelle; Ji, Jinglin; Meenakshi, Immaneni Lakshmi; Lu, Kun; de Villena, Fernando P ... P30ES010126, P42ES031007, R01ES028721, R01ES028721, R01ES029925 Toxicology (2021 03 30) 33524430 Exiting the NIEHS site 2021 
easyXpress: An R package to analyze and visualize high-throughput C. elegans microscopy data generat ...   Nyaanga, Joy; Crombie, Timothy A; Widmayer, Samuel J; Andersen, Erik C R01ES029930 PLoS One (2021) 34383778 Exiting the NIEHS site 2021 
Educational note: addressing special cases of bias that frequently occur in perinatal epidemiology.   Neophytou, Andreas M; Kioumourtzoglou, Marianthi-Anna; Goin, Dana E; Darwin, Kristin C; Casey, ... P30ES000002, P30ES009089, R00ES027023, R00ES027023, R00ES027511, R01ES029943, R01ES029943 Int J Epidemiol (2021 03 03) 33367719 Exiting the NIEHS site 2021 
Effects of GSTT1 Genotype on the Detoxification of 1,3-Butadiene Derived Diepoxide and Formation of ...   Boysen, Gunnar; Arora, Rashi; Degner, Amanda; Vevang, Karin R; Chao, Christopher; Rodriguez, F ... R01ES029911 Chem Res Toxicol (2021 01 18) 33381973 Exiting the NIEHS site 2021 
Erratum: "Rare, protein-altering variants in AS3MT and arsenic metabolism efficiency: a multi-popula ...   Delgado, Dayana A; Chernoff, Meytal; Huang, Lei; Tong, Lin; Chen, Lin; Jasmine, Farzana; Shink ... R35ES028379 Environ Health Perspect (2021 May) 34038222 Exiting the NIEHS site 2021 
From QTL to gene: C. elegans facilitates discoveries of the genetic mechanisms underlying natural va ...   Evans, Kathryn S; van Wijk, Marijke H; McGrath, Patrick T; Andersen, Erik C; Sterken, Mark G R01ES029930 Trends Genet (2021 10) 34229867 Exiting the NIEHS site 2021 
Genetically Increased Telomere Length and Aging-Related Traits in the U.K. Biobank.   Demanelis, Kathryn; Tong, Lin; Pierce, Brandon L R35ES028379 J Gerontol A Biol Sci Med Sci (2021 01 01) 31603979 Exiting the NIEHS site 2021 
HMGB1 as a therapeutic target in disease.   Xue, Jiaming; Suarez, Joelle S; Minaai, Michael; Li, Shuangjing; Gaudino, Giovanni; Pass, Harv ... R01ES030948 J Cell Physiol (2021 05) 33107103 Exiting the NIEHS site 2021 
Intra- and Inter-Species Variability in Urinary N7-(1-Hydroxy-3-buten-2-yl)guanine Adducts Following ...   Erber, Luke; Goodman, Samantha; Wright, Fred A; Chiu, Weihsueh A; Tretyakova, Natalia Y; Rusyn, ... R01ES029911, T32ES026568 Chem Res Toxicol (2021 11 15) 34726909 Exiting the NIEHS site 2021 
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores tha ...   Võsa, Urmo; Claringbould, Annique; Westra, Harm-Jan; Bonder, Marc Jan; Deelen, Patrick; Zeng, ... R35ES028379 Nat Genet (2021 09) 34475573 Exiting the NIEHS site 2021 
Meta-analysis suggests the microbiome responds to Evolve and Resequence experiments in Drosophila me ...   Henry, Lucas P; Ayroles, Julien F R01ES029929 BMC Microbiol (2021 04 09) 33836662 Exiting the NIEHS site 2021 
Mouse Genetic Reference Populations: Cellular Platforms for Integrative Systems Genetics.   Swanzey, Emily; O'Connor, Callan; Reinholdt, Laura G R01ES029916 Trends Genet (2021 03) 33010949 Exiting the NIEHS site 2021 
Origins, fate, and actions of methylated trivalent metabolites of inorganic arsenic: progress and pr ...   Stýblo, Miroslav; Venkatratnam, Abhishek; Fry, Rebecca C; Thomas, David J P42ES031007, R01ES028721, R01ES028721, R01ES029925, R01ES032643, R01ES032643 Arch Toxicol (2021 05) 33768354 Exiting the NIEHS site 2021 
Quantitative NanoLC/NSI+-HRMS Method for 1,3-Butadiene Induced bis-N7-guanine DNA-DNA Cross-Links in ...   Erber, Luke; Goodman, Samantha; Jokipii Krueger, Caitlin C; Rusyn, Ivan; Tretyakova, Natalia R01ES029911, T32ES026568 Toxics (2021 Oct 02) 34678943 Exiting the NIEHS site 2021 
Rare, Protein-Altering Variants in AS3MT and Arsenic Metabolism Efficiency: A Multi-Population Assoc ...   Delgado, Dayana A; Chernoff, Meytal; Huang, Lei; Tong, Lin; Chen, Lin; Jasmine, Farzana; Shink ... P30ES009089, P30ES027792, R24ES028532, R35ES028379 Environ Health Perspect (2021 04) 33826413 Exiting the NIEHS site 2021 
Selfing is the safest sex for Caenorhabditis tropicalis.   Noble, Luke M; Yuen, John; Stevens, Lewis; Moya, Nicolas; Persaud, Riaad; Moscatelli, Marc; Ja ... R01ES029930 Elife (2021 01 11) 33427200 Exiting the NIEHS site 2021 
Sex-dependent effects of preconception exposure to arsenite on gene transcription in parental germ c ...   Venkatratnam, Abhishek; Douillet, Christelle; Topping, Brent C; Shi, Qing; Addo, Kezia A; Idera ... P30ES010126, P42ES031007, R01ES028721, R01ES028721, R01ES029925, T32ES007126 Arch Toxicol (2021 02) 33145626 Exiting the NIEHS site 2021 
Suppression gene drive in continuous space can result in unstable persistence of both drive and wild ...   Champer, Jackson; Kim, Isabel K; Champer, Samuel E; Clark, Andrew G; Messer, Philipp W R01ES029929 Mol Ecol (2021 02) 33404162 Exiting the NIEHS site 2021 
Temporal changes in soluble angiotensin-converting enzyme 2 associated with metabolic health, body c ...   Cauwenberghs, Nicholas; Prunicki, Mary; Sabovčik, František; Perelman, Dalia; Contrepois, Kévin ... R21ES033049 Am J Clin Nutr (2021 11 08) 34375388 Exiting the NIEHS site 2021 
Traffic-related air pollution is associated with glucose dysregulation, blood pressure, and oxidativ ...   Mann, Jennifer K; Lutzker, Liza; Holm, Stephanie M; Margolis, Helene G; Neophytou, Andreas M; E ... R00ES027511, R24ES030888 Environ Res (2021 04) 33587949 Exiting the NIEHS site 2021 
Xenobiotic metabolism and transport in Caenorhabditis elegans.   Hartman, Jessica H; Widmayer, Samuel J; Bergemann, Christina M; King, Dillon E; Morton, Katheri ... P42ES010356, R00ES029552, R01ES029930, T32ES021432 J Toxicol Environ Health B Crit Rev (2021 02 17) 33616007 Exiting the NIEHS site 2021 
A naturally-occurring 22-bp coding deletion in Ugt86Dd reduces nicotine resistance in Drosophila mel ...   Macdonald, Stuart J; Highfill, Chad A R01ES029922 BMC Res Notes (2020 Mar 30) 32228671 Exiting the NIEHS site 2020 
A Robust Method Uncovers Significant Context-Specific Heritability in Diverse Complex Traits.   Dahl, Andy; Nguyen, Khiem; Cai, Na; Gandal, Michael J; Flint, Jonathan; Zaitlen, Noah R01ES029929 Am J Hum Genet (2020 01 02) 31901249 Exiting the NIEHS site 2020 
Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy.   Xue, Jiaming; Patergnani, Simone; Giorgi, Carlotta; Suarez, Joelle; Goto, Keisuke; Bononi, Ang ... R01ES030948 Proc Natl Acad Sci U S A (2020 10 13) 32999071 Exiting the NIEHS site 2020 
Assessing the impact of arsenic metabolism efficiency on DNA methylation using Mendelian randomizati ...   DiGiovanni, Anthony; Demanelis, Kathryn; Tong, Lin; Argos, Maria; Shinkle, Justin; Jasmine, Fa ... P30ES009089, R35ES028379 Environ Epidemiol (2020 Apr) 32337471 Exiting the NIEHS site 2020 
Biological Mechanisms and Clinical Significance of BAP1 Mutations in Human Cancer.   Carbone, Michele; Harbour, J William; Brugarolas, James; Bononi, Angela; Pagano, Ian; Dey, Anw ... R01ES030948 Cancer Discov (2020 08) 32690542 Exiting the NIEHS site 2020 
Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducib ...   Sigmon, John Sebastian; Blanchard, Matthew W; Baric, Ralph S; Bell, Timothy A; Brennan, Jennife ... P42ES031007, R01ES029925 Genetics (2020 12) 33067325 Exiting the NIEHS site 2020 
Determinants of telomere length across human tissues.   Demanelis, Kathryn; Jasmine, Farzana; Chen, Lin S; Chernoff, Meytal; Tong, Lin; Delgado, Dayan ... P30ES027792, R35ES028379 Science (2020 09 11) 32913074 Exiting the NIEHS site 2020 
Efficient Estimation and Applications of Cross-Validated Genetic Predictions to Polygenic Risk Score ...   Mefford, Joel; Park, Danny; Zheng, Zhili; Ko, Arthur; Ala-Korpela, Mika; Laakso, Markku; Pajuk ... R01ES029929 J Comput Biol (2020 04) 32077750 Exiting the NIEHS site 2020 
Gabra2 is a genetic modifier of Scn8a encephalopathy in the mouse.   Yu, Wenxi; Hill, Sophie F; Xenakis, James G; Pardo-Manuel de Villena, Fernando; Wagnon, Jacy L; ... R01ES029925 Epilepsia (2020 12) 33140451 Exiting the NIEHS site 2020 
Genetic Determinants of Reduced Arsenic Metabolism Efficiency in the 10q24.32 Region Are Associated ...   Chernoff, Meytal; Tong, Lin; Demanelis, Kathryn; Vander Griend, Donald; Ahsan, Habib; Pierce, ... P30ES027792, R35ES028379 Toxicol Sci (2020 08 01) 32433756 Exiting the NIEHS site 2020 
Heterozygous germline BLM mutations increase susceptibility to asbestos and mesothelioma.   Bononi, Angela; Goto, Keisuke; Ak, Guntulu; Yoshikawa, Yoshie; Emi, Mitsuru; Pastorino, Sandra ... R01ES030948 Proc Natl Acad Sci U S A (2020 12 29) 33318203 Exiting the NIEHS site 2020 
Improved asthma outcomes observed in the vicinity of coal power plant retirement, retrofit, and conv ...   Casey, Joan A; Su, Jason G; Henneman, Lucas R F; Zigler, Corwin; Neophytou, Andreas M; Catalano ... P30ES009089, R00ES027023, R00ES027023, R00ES027511, R01ES026217 Nat Energy (2020 May) 32483491 Exiting the NIEHS site 2020 
Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patt ...   Keele, Gregory R; Quach, Bryan C; Israel, Jennifer W; Chappell, Grace A; Lewis, Lauren; Safi, ... P30ES010126, P30ES025128, R01ES029911 PLoS Genet (2020 01) 31961859 Exiting the NIEHS site 2020 
Interindividual Differences in DNA Adduct Formation and Detoxification of 1,3-Butadiene-Derived Epox ...   Degner, Amanda; Arora, Rashi; Erber, Luke; Chao, Christopher; Peterson, Lisa A; Tretyakova, Na ... R01ES029911 Chem Res Toxicol (2020 07 20) 32237725 Exiting the NIEHS site 2020 
Low-Dose Silver Nanoparticle Surface Chemistry and Temporal Effects on Gene Expression in Human Live ...   House, John S; Bouzos, Evangelia; Fahy, Kira M; Francisco, Victorino Miguel; Lloyd, Dillon T; W ... P42ES027704, R01ES029911 Small (2020 05) 32227433 Exiting the NIEHS site 2020 
Modeling epistasis in mice and yeast using the proportion of two or more distinct genetic background ...   Rau, Christoph D; Gonzales, Natalia M; Bloom, Joshua S; Park, Danny; Ayroles, Julien; Palmer, ... R01ES029929 PLoS Genet (2020 10) 33104702 Exiting the NIEHS site 2020 
Natural variation in the sequestosome-related gene, sqst-5, underlies zinc homeostasis in Caenorhabd ...   Evans, Kathryn S; Zdraljevic, Stefan; Stevens, Lewis; Collins, Kimberly; Tanny, Robyn E; Anders ... R01ES029930 PLoS Genet (2020 11) 33175833 Exiting the NIEHS site 2020 
Primo: integration of multiple GWAS and omics QTL summary statistics for elucidation of molecular me ...   Gleason, Kevin J; Yang, Fan; Pierce, Brandon L; He, Xin; Chen, Lin S R35ES028379 Genome Biol (2020 09 11) 32912334 Exiting the NIEHS site 2020 
Research Participants' Attitudes towards Receiving Information on Genetic Susceptibility to Arsenic ...   Tamayo, Lizeth I; Lin, Hannah; Ahmed, Alauddin; Shahriar, Hasan; Hasan, Rabiul; Sarwar, Golam; ... P30ES027792, R24ES028532, R35ES028379 Public Health Genomics (2020) 32069464 Exiting the NIEHS site 2020 
The cadmium-responsive gene, cdr-6, does not influence Caenorhabditis elegans responses to exogenous ...   Evans, Kathryn S; Andersen, Erik C R01ES029930 MicroPubl Biol (2020 Sep 14) 33005884 Exiting the NIEHS site 2020 
The Evolution of Variance Control.   Bruijning, Marjolein; Metcalf, C Jessica E; Jongejans, Eelke; Ayroles, Julien F R01ES029929 Trends Ecol Evol (2020 01) 31519463 Exiting the NIEHS site 2020 
The Gene scb-1 Underlies Variation in Caenorhabditis elegans Chemotherapeutic Responses.   Evans, Kathryn S; Andersen, Erik C R01ES029930 G3 (Bethesda) (2020 07 07) 32385045 Exiting the NIEHS site 2020 
TM3'seq: A Tagmentation-Mediated 3' Sequencing Approach for Improving Scalability of RNAseq Experime ...   Pallares, Luisa F; Picard, Serge; Ayroles, Julien F R01ES029929 G3 (Bethesda) (2020 01 07) 31676507 Exiting the NIEHS site 2020 
Tumour predisposition and cancer syndromes as models to study gene-environment interactions.   Carbone, Michele; Arron, Sarah T; Beutler, Bruce; Bononi, Angela; Cavenee, Webster; Cleaver, J ... R01ES030948 Nat Rev Cancer (2020 09) 32472073 Exiting the NIEHS site 2020 
Using Genetic and Species Diversity to Tackle Kidney Disease.   Garrett, Michael R; Korstanje, Ron R01ES029916 Trends Genet (2020 07) 32362446 Exiting the NIEHS site 2020 
A missense variant in FTCD is associated with arsenic metabolism and toxicity phenotypes in Banglade ...   Pierce, Brandon L; Tong, Lin; Dean, Samantha; Argos, Maria; Jasmine, Farzana; Rakibuz-Zaman, M ... P30ES009089, P30ES027792, R24ES028532, R35ES028379 PLoS Genet (2019 03) 30893314 Exiting the NIEHS site 2019 
A Novel Gene Underlies Bleomycin-Response Variation in Caenorhabditis elegans.   Brady, Shannon C; Zdraljevic, Stefan; Bisaga, Karol W; Tanny, Robyn E; Cook, Daniel E; Lee, Da ... R01ES029930 Genetics (2019 08) 31171655 Exiting the NIEHS site 2019 
Acute effects of air pollution on mortality: A 17-year analysis in Kuwait.   Achilleos, Souzana; Al-Ozairi, Ebaa; Alahmad, Barrak; Garshick, Eric; Neophytou, Andreas M; Bou ... R00ES027511 Environ Int (2019 05) 30844583 Exiting the NIEHS site 2019 
Association of Arsenic Exposure with Whole Blood DNA Methylation: An Epigenome-Wide Study of Banglad ...   Demanelis, Kathryn; Argos, Maria; Tong, Lin; Shinkle, Justin; Sabarinathan, Mekala; Rakibuz-Zam ... P30ES009089, P30ES027792, R24ES028532, R35ES028379 Environ Health Perspect (2019 05) 31135185 Exiting the NIEHS site 2019 
Differential metabolism of inorganic arsenic in mice from genetically diverse Collaborative Cross st ...   Stýblo, Miroslav; Douillet, Christelle; Bangma, Jacqueline; Eaves, Lauren A; de Villena, Fernan ... R01ES028721, R01ES028721, R01ES029925 Arch Toxicol (2019 10) 31493028 Exiting the NIEHS site 2019 
Effects of Preconception and in Utero Inorganic Arsenic Exposure on the Metabolic Phenotype of Genet ...   Fry, Rebecca C; Addo, Kezia A; Bell, Timothy A; Douillet, Christelle; Martin, Elizabeth; Stýblo ... P30ES010126, R01ES029925, T32ES007126 Chem Res Toxicol (2019 08 19) 31251040 Exiting the NIEHS site 2019 
In utero tobacco smoke exposure, DNA methylation, and asthma in Latino children.   Neophytou, Andreas M; Oh, Sam S; Hu, Donglei; Huntsman, Scott; Eng, Celeste; Rodríguez-Santana, ... R00ES027511 Environ Epidemiol (2019 Jun) 31342008 Exiting the NIEHS site 2019 
Natural variation in C. elegans arsenic toxicity is explained by differences in branched chain amino ...   Zdraljevic, Stefan; Fox, Bennett William; Strand, Christine; Panda, Oishika; Tenjo, Francisco J ... R01ES029930 Elife (2019 04 08) 30958264 Exiting the NIEHS site 2019 
Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the Mouse.   Lewis, Lauren; Borowa-Mazgaj, Barbara; de Conti, Aline; Chappell, Grace A; Luo, Yu-Syuan; Bodna ... R01ES029911 Chem Res Toxicol (2019 05 20) 30990016 Exiting the NIEHS site 2019 
Sex-specific differences in genotoxic and epigenetic effects of 1,3-butadiene among mouse tissues.   Lewis, Lauren; Chappell, Grace A; Kobets, Tetyana; O'Brian, Bridget E; Sangaraju, Dewakar; Kosy ... P30ES029067, R01ES029911 Arch Toxicol (2019 03) 30552462 Exiting the NIEHS site 2019 
The contribution of parent-to-offspring transmission of telomeres to the heritability of telomere le ...   Delgado, Dayana A; Zhang, Chenan; Gleason, Kevin; Demanelis, Kathryn; Chen, Lin S; Gao, Jianju ... P30ES027792, R24ES028532, R35ES028379 Hum Genet (2019 Jan) 30536049 Exiting the NIEHS site 2019 
The effect of age on DNA methylation in whole blood among Bangladeshi men and women.   Jansen, Rick J; Tong, Lin; Argos, Maria; Jasmine, Farzana; Rakibuz-Zaman, Muhammad; Sarwar, Go ... P30ES027792, R24ES028532, R35ES028379 BMC Genomics (2019 Sep 10) 31506065 Exiting the NIEHS site 2019 
Tightly linked antagonistic-effect loci underlie polygenic phenotypic variation in C. elegans.   Bernstein, Max R; Zdraljevic, Stefan; Andersen, Erik C; Rockman, Matthew V R01ES029930 Evol Lett (2019 Oct) 31636939 Exiting the NIEHS site 2019 
Using Collaborative Cross Mouse Population to Fill Data Gaps in Risk Assessment: A Case Study of Pop ...   Luo, Yu-Syuan; Cichocki, Joseph A; Hsieh, Nan-Hung; Lewis, Lauren; Wright, Fred A; Threadgill, ... P30ES029067, P42ES027704, R01ES029911 Environ Health Perspect (2019 06) 31246107 Exiting the NIEHS site 2019 
A novel pooled-sample multiplex luminex assay for high-throughput measurement of relative telomere l ...   Jasmine, Farzana; Shinkle, Justin; Sabarinathan, Mekala; Ahsan, Habibul; Pierce, Brandon L; Kib ... R35ES028379 Am J Hum Biol (2018 07) 29527774 Exiting the NIEHS site 2018 
A study of telomere length, arsenic exposure, and arsenic toxicity in a Bangladeshi cohort.   Zhang, Chenan; Kibriya, Muhammad G; Jasmine, Farzana; Roy, Shantanu; Gao, Jianjun; Sabarinathan ... P30ES027792, R24ES028532, R35ES028379 Environ Res (2018 07) 29567420 Exiting the NIEHS site 2018 
Co-occurring expression and methylation QTLs allow detection of common causal variants and shared bi ...   Pierce, Brandon L; Tong, Lin; Argos, Maria; Demanelis, Kathryn; Jasmine, Farzana; Rakibuz-Zaman ... P30ES027792, R35ES028379 Nat Commun (2018 02 23) 29476079 Exiting the NIEHS site 2018 
Genome-wide association study of telomere length among South Asians identifies a second RTEL1 associ ...   Delgado, Dayana A; Zhang, Chenan; Chen, Lin S; Gao, Jianjun; Roy, Shantanu; Shinkle, Justin; S ... P30ES027792, R35ES028379 J Med Genet (2018 01) 29151059 Exiting the NIEHS site 2018 
Screening for gene-environment (G×E) interaction using omics data from exposed individuals: an appli ...   Argos, Maria; Tong, Lin; Roy, Shantanu; Sabarinathan, Mekala; Ahmed, Alauddin; Islam, Md Tariq ... P30ES009089, P30ES027792, R35ES028379 Mamm Genome (2018 02) 29453499 Exiting the NIEHS site 2018 
Incorporation of Biological Knowledge Into the Study of Gene-Environment Interactions.   Ritchie, Marylyn D; Davis, Joe R; Aschard, Hugues; Battle, Alexis; Conti, David; Du, Mengmeng; ... P30ES007048, R35ES028379 Am J Epidemiol (2017 Oct 01) 28978191 Exiting the NIEHS site 2017 
Lessons Learned From Past Gene-Environment Interaction Successes.   Ritz, Beate R; Chatterjee, Nilanjan; Garcia-Closas, Montserrat; Gauderman, W James; Pierce, Bra ... P30ES007048, R35ES028379 Am J Epidemiol (2017 Oct 01) 28978190 Exiting the NIEHS site 2017 
The association between telomere length and mortality in Bangladesh.   Dean, Samantha G; Zhang, Chenan; Gao, Jianjun; Roy, Shantanu; Shinkle, Justin; Sabarinathan, M ... R35ES028379 Aging (Albany NY) (2017 Jun 15) 28630379 Exiting the NIEHS site 2017 
Initiation and termination of DNA replication during S phase in relation to cyclins D1, E and A, p21 ...   Darzynkiewicz, Zbigniew; Zhao, Hong; Zhang, Sufang; Lee, Marietta Y W T; Lee, Ernest Y C; Zhang ... R56ES014737 Oncotarget (2015 May 20) 26059433 Exiting the NIEHS site 2015 
Expression of the p12 subunit of human DNA polymerase δ (Pol δ), CDK inhibitor p21(WAF1), Cdt1, cycl ...   Zhao, Hong; Zhang, Sufang; Xu, Dazhong; Lee, Marietta Ywt; Zhang, Zhongtao; Lee, Ernest Yc; Da ... R56ES014737 Cell Cycle (2014) 25483089 Exiting the NIEHS site 2014 
The tail that wags the dog: p12, the smallest subunit of DNA polymerase δ, is degraded by ubiquitin ...   Lee, Marietta Y W T; Zhang, Sufang; Lin, Szu Hua Sharon; Wang, Xiaoxiao; Darzynkiewicz, Zbignie ... R56ES014737 Cell Cycle (2014) 24300032 Exiting the NIEHS site 2014 
A novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response ...   Zhang, Sufang; Zhao, Hong; Darzynkiewicz, Zbiegniew; Zhou, Pengbo; Zhang, Zhongtao; Lee, Ernes ... R56ES014737 J Biol Chem (2013 Oct 11) 23913683 Exiting the NIEHS site 2013 
Dynamics of enzymatic interactions during short flap human Okazaki fragment processing by two forms ...   Lin, Szu Hua Sharon; Wang, Xiaoxiao; Zhang, Sufang; Zhang, Zhongtao; Lee, Ernest Y C; Lee, Mar ... R56ES014737 DNA Repair (Amst) (2013 Nov) 24035200 Exiting the NIEHS site 2013 
Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase ...   Zhang, Sufang; Zhou, Yajing; Sarkeshik, Ali; Yates 3rd, John R; Thomson, Timothy M; Zhang, Zho ... R56ES014737 J Biol Chem (2013 Feb 01) 23233665 Exiting the NIEHS site 2013 
PDIP38 is translocated to the spliceosomes/nuclear speckles in response to UV-induced DNA damage and ...   Wong, Agnes; Zhang, Sufang; Mordue, Dana; Wu, Joseph M; Zhang, Zhongtao; Darzynkiewicz, Zbigni ... R56ES014737 Cell Cycle (2013 Oct 01) 23989611 Exiting the NIEHS site 2013 
Characterization of human DNA polymerase delta and its subassemblies reconstituted by expression in ...   Zhou, Yajing; Meng, Xiao; Zhang, Sufang; Lee, Ernest Y C; Lee, Marietta Y W T R56ES014737 PLoS One (2012) 22723953 Exiting the NIEHS site 2012 
Phosphorylation of the p68 subunit of Pol δ acts as a molecular switch to regulate its interaction w ...   Rahmeh, Amal A; Zhou, Yajing; Xie, Bin; Li, Hao; Lee, Ernest Y C; Lee, Marietta Y W T R56ES014737 Biochemistry (2012 Jan 10) 22148433 Exiting the NIEHS site 2012 
Regulation of human DNA polymerase delta in the cellular responses to DNA damage.   Lee, Marietta Y W T; Zhang, Sufang; Lin, Szu Hua Sharon; Chea, Jennifer; Wang, Xiaoxiao; LeRoy, ... R56ES014737 Environ Mol Mutagen (2012 Dec) 23047826 Exiting the NIEHS site 2012 
Spatiotemporal recruitment of human DNA polymerase delta to sites of UV damage.   Chea, Jennifer; Zhang, Sufang; Zhao, Hong; Zhang, Zhongtao; Lee, Ernest Y C; Darzynkiewicz, Zb ... R56ES014737 Cell Cycle (2012 Aug 01) 22801543 Exiting the NIEHS site 2012 
Structure of monoubiquitinated PCNA: implications for DNA polymerase switching and Okazaki fragment ...   Zhang, Zhongtao; Zhang, Sufang; Lin, Szu Hua Sharon; Wang, Xiaoxiao; Wu, Licheng; Lee, Ernest ... R56ES014737 Cell Cycle (2012 Jun 01) 22592530 Exiting the NIEHS site 2012 
The p12 subunit of human polymerase delta modulates the rate and fidelity of DNA synthesis.   Meng, Xiao; Zhou, Yajing; Lee, Ernest Y C; Lee, Marietta Y W T; Frick, David N R56ES014737 Biochemistry (2010 May 04) 20334433 Exiting the NIEHS site 2010 
DNA damage alters DNA polymerase delta to a form that exhibits increased discrimination against modi ...   Meng, Xiao; Zhou, Yajing; Zhang, Sufang; Lee, Ernest Y C; Frick, David N; Lee, Marietta Y W T R56ES014737 Nucleic Acids Res (2009 Feb) 19074196 Exiting the NIEHS site 2009 
PCNA is ubiquitinated by RNF8.   Zhang, Sufang; Chea, Jennifer; Meng, Xiao; Zhou, Yajing; Lee, Ernest Y C; Lee, Marietta Y W T R56ES014737 Cell Cycle (2008 Nov 01) 18948756 Exiting the NIEHS site 2008 
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