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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Person Details: Katrina M. Waters

Superfund Research Program

Katrina M. Waters

Pacific Northwest National Laboratory
Biological Sciences Division
902 Battelle Blvd; MSIN J4-18
Richland, Washington 99352
Phone: 509-375-3907
Email: katrina.waters@pnnl.gov

Projects

Publications

2024

  • Bramer L, Dixon HM, Degnan D, Rohlman D, Herbstman JB, Anderson KA, Waters KM. 2024. Expanding the access of wearable silicone wristbands in community-engaged research through best practices in data analysis and integration. Pac Symp Biocomput 29:170-186. PMID:38160278 PMCID:PMC10766083
  • Bramer L, Dixon HM, Rohlman D, Scott RP, Miller RL, Kincl L, Herbstman JB, Waters KM, Anderson KA. 2024. PM2.5 is insufficient to explain personal PAH exposure. Geohealth 8(2):doi:10.1029/2023gh000937 PMID:38344245 PMCID:10858395

2023

  • Gosline S, Kim DN, Pande P, Thomas DG, Truong L, Hoffman PD, Barton ML, Loftus J, Moran A, Hampton S, Dowson S, Franklin L, Degnan D, Anderson LN, Thessen AE, Tanguay RL, Anderson KA, Waters KM. 2023. The Superfund Research Program Analytics Portal: linking environmental chemical exposure to biological phenotypes. Sci Data 10(1):151. doi:10.1038/s41597-023-02021-5 PMID:36944655 PMCID:PMC1003089
  • McClure RS, Rericha Y, Waters KM, Tanguay RL. 2023. 3' RNA-seq is superior to standard RNA-seq in cases of sparse data but inferior at identifying toxicity pathways in a model organism. Front Bioinform 3:1234218. doi:10.3389/fbinf.2023.1234218 PMID:37576716 PMCID:PMC10414111
  • Rude CI, Tidwell LG, Tilton SC, Waters KM, Anderson KA, Tanguay RL. 2023. Coupling environmental whole mixture toxicity screening with unbiased RNA-Seq reveals site-specific biological responses in zebrafish. Toxics 11(3):201. doi:10.3390/toxics11030201 PMID:36976966 PMCID:PMC1005377

2022

  • Dixon HM, Bramer LM, Scott RP, Calero L, Holmes D, Gibson EA, Cavalier HM, Rohlman D, Miller RL, Calafat AM, Kincl L, Waters KM, Herbstman JB, Anderson KA. 2022. Evaluating predictive relationships between wristbands and urine for assessment of personal PAH exposure. Environ Int 163:doi:10.1016/j.envint.2022.107226 PMID:35405507 PMCID:PMC8978533
  • Evoy R, Kincl L, Rohlman D, Bramer LM, Dixon HM, Hystad P, Bae H, Barton ML, Phillips AR, Miller RL, Waters KM, Herbstman JB, Anderson KA. 2022. Impact of acute temperature and air pollution exposures on adult lung function: A panel study of asthmatics. PLoS One 17(6):e0270412. doi:10.1371/journal.pone.0270412 PMID:35763502 PMCID:PMC9239441
  • Shankar P, Garcia GR, La Du JK, Sullivan CM, Dunham CL, Goodale BC, Waters KM, Stanisheuski S, Maier C, Thunga P, Reif DM, Tanguay RL. 2022. The Ahr2-Dependent wfikkn1 gene influences zebrafish transcriptome, proteome, and behavior. Toxicol Sci doi:10.1093/toxsci/kfac037 PMID:35377459
  • Wilson LB, McClure RS, Waters KM, Simonich MT, Tanguay RL. 2022. Concentration-response gene expression analysis in zebrafish reveals phenotypically-anchored transcriptional responses to retene. Front Toxicol 4:950503. doi:10.3389/ftox.2022.950503 PMID:36093370 PMCID:PMC9453431

2021

  • Mansouri K, Karmaus AL, Fitzpatrick J, Patlewicz G, Pradeep P, Alberga D, Alepee N, Allen TE, Allen D, Alves VM, Andrade CH, Auernhammer TR, Ballabio D, Bell S, Benfenati E, Bhattacharya S, Bastos JV, Boyd SA, Brown BJ, Capuzzi SJ, Chushak Y, Ciallella H, Clark AM, Consonni V, Daga PR, Ekins S, Farag S, Fedorov M, Fourches D, Gadaleta D, Gao F, Gearhart JM, Goh G, Goodman JM, Grisoni F, Grulke CM, Hartung T, Hirn M, Karpov P, Korotcov A, Lavado GJ, Lawless M, Luechtefeld T, Li X, Lunghini F, Mangiatordi GF, Marcou G, Marsh DE, Martin T, Mauri A, Muratov EN, Myatt GJ, Nguyen D, Nicolotti O, Note R, Pande P, Parks AK, Peryea T, Polash AH, Rallo R, Roncaglioni A, Rowlands C, Ruiz P, Russo DP, Sayed A, Sayre R, Sheils T, Siegel C, Silva AC, Simeonov A, Sosnin S, Southall N, Strickland J, Tang Y, Teppen BJ, Tetko IV, Thomas DG, Tkachenko V, Todeschini R, Toma C, Tripodi I, Trisciuzzi D, Tropsha A, Varnek A, Vukovic K, Wang Z, Wang L, Waters KM, Wedlake AJ, Wijeyesakere SJ, Wilson D, Xiao Z, Yang H, Zahoranszky-Kohalmi G, Zakharov AV, Zhang F, Zhang Z, Zhao T, Zhu H, Zorn KM, Casey W, Kleinstreuer N. 2021. CATMoS: Collaborative Acute Toxicity Modeling Suite. Environ Health Perspect 129(4):47013. doi:10.1289/EHP8495 PMID:33929906 PMCID:PMC8086800
  • Shankar P, McClure RS, Waters KM, Tanguay RL. 2021. Gene co-expression network analysis in zebrafish reveals chemical class specific modules. BMC Genomics 22:doi:10.1186/s12864-021-07940-4 PMID:34517816 PMCID:PMC8438978

2020

2019

  • Brown J, Phillips AR, Lewis DA, Mans M, Chang Y, Tanguay RL, Peterson ES, Waters KM, Tilton SC. 2019. Bioinformatics Resource Manager: a systems biology web tool for microRNA and omics data integration. BMC Bioinformatics 20:255. doi:10.1186/s12859-019-2805-6 PMID:31101000
  • Burnum-Johnson KE, Zheng X, Dodds J, Ash J, Fourches D, Nicora CD, Wendler J, Metz TO, Waters KM, Jansson J, Smith RD, Baker ES. 2019. Ion mobility spectrometry and the omics: Distinguishing isomers, isobars, molecular classes and contaminant ions in complex samples. Trends in Analytical Chemistry 116:292-299. doi:10.1016/j.trac.2019.04.022 PMID:31798197 PMCID:PMC6887105
  • Dixon HM, Armstrong G, Barton ML, Bergmann AJ, Bondy M, Halbleib ML, Hamilton W, Haynes E, Herbstman JB, Hoffman PD, Jepson PC, Kile ML, Kincl L, Laurienti PJ, North P, Paulik LB, Petrosino J, Points GL, Poutasse C, Rohlman D, Scott RP, Smith BW, Tidwell LG, Walker C, Waters KM, Anderson KA. 2019. Discovery of common chemical exposures across three continents using silicone wristbands. R Soc Open Sci 6(2):181836. doi:10.1098/rsos.181836 PMID:30891293 PMCID:PMC6408398
  • Madeen E, Siddens LK, Uesugi S, McQuistan TJ, Corley RA, Smith JN, Waters KM, Tilton SC, Anderson KA, Ognibene T, Turteltaub KW, Williams DE. 2019. Toxicokinetics of benzo[a]pyrene in humans: Extensive metabolism as determined by UPLC-accelerator mass spectrometry following oral micro-dosing. Toxicol Appl Pharmacol 364:97-105. doi:10.1016/j.taap.2018.12.010 PMID:30582946 PMCID:PMC6369707
  • Messier KP, Tidwell LG, Ghetu CC, Rohlman D, Scott RP, Bramer LM, Dixon HM, Waters KM, Anderson KA. 2019. Indoor versus outdoor air quality during wildfires. Environ Sci Technol Lett 6:696-701. doi:10.1021/acs.estlett.9b00599
  • Rohlman D, Dixon HM, Kincl L, Larkin A, Evoy R, Barton ML, Phillips AR, Peterson ES, Scaffidi C, Herbstman JB, Waters KM, Anderson KA. 2019. Development of an environmental health tool linking chemical exposures, physical location and lung function. BMC Public Health 19(1):854. doi:10.1186/s12889-019-7217-z PMID:31262274 PMCID:PMC6604385
  • Shankar P, Geier MC, Truong L, McClure RS, Pande P, Waters KM, Tanguay RL. 2019. Coupling genome-wide transcriptomics and developmental toxicity profiles in zebrafish to characterize polycyclic aromatic hydrocarbon (PAH) hazard. Int J Mol Sci 20:2570. doi:10.3390/ijms20102570 PMID:31130617 PMCID:PMC6566387
  • Thomas DG, Shankaran H, Truong L, Tanguay RL, Waters KM. 2019. Time-dependent behavioral data from zebrafish reveals novel signatures of chemical toxicity using point of departure analysis. Comput Toxicol 9:50-60. doi:10.1016/j.comtox.2018.11.001 PMID:31485548 PMCID:PMC6726397

2018

2017

  • Davie-Martin C, Stratton KG, Teeguarden J, Waters KM, Simonich SL. 2017. Implications of bioremediation of polycyclic aromatic hydrocarbon contaminated soils for human health and cancer risk. Environ Sci Technol 51:9458-9468. doi:10.1021/acs.est.7b02956 PMID:28836766
  • Madeen E, Lohr CV, Siddens LK, Krueger SK, Dashwood RH, Gonzalez FJ, Baird WM, Ho E, Bramer LM, Waters KM, Williams DE, You H. 2017. Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice. Mol Carcinog 56(1):163-171. doi:10.1002/mc.22480 PMID:26990437
  • Wittwehr C, Aladjov H, Ankley GT, Byrne H, de Knecht J, Heinzle E, Klambauer G, Landesmann b, Luijten M, MacKay C, Maxwell G, Meek MB, Paini A, Perkins EJ, Sobanski T, Villeneuve DL, Waters KM, Whelan M. 2017. How adverse outcome pathways can aid the development and use of computational prediction models for regulatory toxicology. Toxicol Sci 155(2):326-336. doi:10.1093/toxsci/kfw207 PMID:27994170 PMCID:PMC5340205

2016

  • Haggard DE, Noyes PD, Waters KM, Tanguay RL. 2016. Phenotypically anchored transcriptome profiling of developmental exposure to the antimicrobial agent, triclosan, reveals hepatotoxicity in embryonic zebrafish. Toxicol Appl Pharmacol 308:32-45. doi:10.1016/j.taap.2016.08.013 PMID:27538710 PMCID:PMC5023494
  • Teeguarden J, Tan Y, Edwards SW, Leonard JA, Anderson KA, Corley RA, Harding A, Kile ML, Simonich SL, Stone D, Tanguay RL, Waters KM, Harper SL, Williams DE. 2016. Expanding on successful concepts, models, and organization. Environ Sci Technol 50(17):8921-8922. doi:10.1021/acs.est.6b03027 PMID:27509267
  • Teeguarden J, Tan Y, Edwards SW, Leonard JA, Anderson KA, Corley RA, Kile ML, Simonich SL, Stone D, Tanguay RL, Waters KM, Harper SL, Williams DE. 2016. Completing the link between exposure science and toxicology for improved environmental health decision making: the aggregate exposure pathway framework. Environ Sci Technol 50(9):4579-4586. doi:10.1021/acs.est.5b05311 PMID:26759916 PMCID:PMC4854780

2015

  • Goodale BC, La Du JK, Tilton SC, Sullivan CM, Bisson WH, Waters KM, Tanguay RL. 2015. Ligand-specific transcriptional mechanisms underlie aryl hydrocarbon receptor-mediated developmental toxicity of oxygenated PAHs. Toxicol Sci 147(2):397-411. doi:10.1093/toxsci/kfv139 PMID:26141390 PMCID:PMC4612346
  • Lafontaine S, Schrlau J, Butler J, Jia Y, Harper B, Harris S, Bramer LM, Waters KM, Harding A, Simonich SL. 2015. Relative influence of trans-Pacific and regional atmospheric transport of PAHs in the Pacific Northwest, US. Environ Sci Technol 49(23):13807-13816. doi:10.1021/acs.est.5b00800 PMID:26151337 PMCID:PMC4666789
  • Rohlman D, Syron L, Hobbie KA, Anderson KA, Scaffidi C, Sudakin D, Peterson ES, Waters KM, Haynes E, Arkin L, Feezel P, Kincl LD. 2015. A community-based approach to developing a mobile device for measuring ambient air exposure, location, and respiratory health. Environ Justice 8:126-134. doi:10.1089/env.2015.0001
  • Siddens LK, Bunde KL, Harper TA, McQuistan TJ, Lohr CV, Bramer LM, Waters KM, Tilton SC, Krueger SK, Williams DE, Baird WM. 2015. Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse. Toxicol Appl Pharmacol 287(2):149-160. doi:10.1016/j.taap.2015.05.019 PMID:26049101 PMCID:PMC4689210
  • Tilton SC, Siddens LK, Krueger SK, Larkin A, Lohr CV, Williams DE, Baird WM, Waters KM. 2015. Mechanism-based classification of PAH mixtures to predict carcinogenic potential. Toxicol Sci 146(1):135-145. doi:10.1093/toxsci/kfv080 PMID:25908611 PMCID:PMC4476464

2013

  • Franzosa JA, Bugel SM, Tal TL, La Du JK, Tilton SC, Waters KM, Tanguay RL. 2013. Retinoic acid-dependent regulation of miR-19 expression elicits vertebrate axis defects. FASEB J 27(12):4866-4876. doi:10.1096/fj.12-225524 PMID:23975936 PMCID:PMC3834785
  • Goodale BC, Tilton SC, Corvi MM, Wilson GR, Janszen DB, Anderson KA, Waters KM, Tanguay RL. 2013. Structurally distinct polycyclic aromatic hydrocarbons induce differential transcriptional responses in developing zebrafish. Toxicol Appl Pharmacol 272(3):656-670. doi:10.1016/j.taap.2013.04.024 PMID:23656968 PMCID:PMC4098828
  • Knecht AL, Goodale BC, Truong L, Simonich MT, Swanson AJ, Matzke MM, Anderson KA, Waters KM, Tanguay RL. 2013. Comparative developmental toxicity of environmentally relevant oxygenated PAHs. Toxicol Appl Pharmacol 271(2):266-275. doi:10.1016/j.taap.2013.05.006 PMID:23684558 PMCID:PMC3976560
  • Larkin A, Siddens LK, Krueger SK, Tilton SC, Waters KM, Williams DE, Baird WM. 2013. Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin. Toxicol Appl Pharmacol 267(2):192-199. doi:10.1016/j.taap.2012.12.011 PMID:23274566 PMCID:PMC3626406
  • Motorykin O, Matzke MM, Waters KM, Simonich SL. 2013. Association of carcinogenic polycyclic aromatic hydrocarbon emissions and smoking with lung cancer mortality rates on a global scale. Environ Sci Technol 47(7):3410-3416. doi:10.1021/es305295d PMID:23472838 PMCID:PMC3634325
  • Saili KS, Tilton SC, Waters KM, Tanguay RL. 2013. Global gene expression analysis reveals pathway differences between teratogenic and non-teratogenic exposure concentrations of bisphenol A and 17β-estradiol in embryonic zebrafish. Reprod Toxicol 38:89-101. doi:10.1016/j.reprotox.2013.03.009 PMID:23557687 PMCID:PMC3690774
  • Truong L, Tilton SC, Zaikova T, Richman E, Waters KM, Hutchison JE, Tanguay RL. 2013. Surface functionalities of gold nanoparticles impact embryonic gene expression responses. Nanotechnology 7:192-201. doi:10.3109/17435390.2011.648225 PMID:22263968 PMCID:PMC3399027

2012

  • Chen J, Huang C, Truong L, La Du JK, Tilton SC, Waters KM, Lin K, Tanguay RL, Dong Q. 2012. Early life stage trimethyltin exposure induces ADP-ribosylation factor expression and perturbs the vascular system in zebrafish. Toxicology 302:129-139. doi:10.1016/j.tox.2012.09.004 PMID:23000284 PMCID:PMC3511642
  • Forsberg ND, Stone D, Harding A, Harper B, Harris S, Matzke MM, Cardenas A, Waters KM, Anderson KA. 2012. Effect of Native American fish smoking methods on dietary exposure to polycyclic aromatic hydrocarbons and possible risks to human health. J Agric Food Chem 60(27):6899-6906. doi:10.1021/jf300978m PMID:22690788 PMCID:PMC3567306
  • Goodale BC, La Du JK, Bisson WH, Janszen DB, Waters KM, Tanguay RL. 2012. AHR2 mutant reveals functional diversity of aryl hydrocarbon receptors in Zebrafish. PLoS One 7(1):e29346. doi:10.1371/journal.pone.0029346 PMID:22242167 PMCID:PMC3252317
  • Hobbie KA, Peterson ES, Barton ML, Waters KM, Anderson KA. 2012. Integration of data systems and technology improves research and collaboration for a Superfund Research Center. J Lab Autom 17(4):275-283. doi:10.1177/2211068212448428 PMID:22651935 PMCID:PMC3460553
  • Matzke MM, Allan SE, Anderson KA, Waters KM. 2012. An approach for calculating a confidence interval from a single aquatic sample for monitoring hydrophobic organic contaminants. Environ Toxicol Chem 31(12):2888-2892. doi:10.1002/etc.2014 PMID:22997050 PMCID:PMC3581149
  • Shorey LE, Castro DJ, Baird WM, Siddens LK, Lohr CV, Matzke MM, Waters KM, Corley RA, Williams DE. 2012. Transplacental carcinogenesis with dibenzo[def,p]chrysene (DBC): Timing of maternal exposures determines target tissue response in offspring. Cancer Lett 317(1):49-55. doi:10.1016/j.canlet.2011.11.010 PMID:22085489 PMCID:PMC3269513
  • Siddens LK, Larkin A, Krueger SK, Bradfield CA, Waters KM, Tilton SC, Pereira CB, Lohr CV, Arlt VM, Phillips DH, Williams DE, Baird WM. 2012. Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse. Toxicol Appl Pharmacol 264(3):377-386. doi:10.1016/j.taap.2012.08.014 PMID:22935520 PMCID:PMC3483092
  • Tal TL, Franzosa JA, Tilton SC, Philbrick KA, Iwaniec UT, Turner RT, Waters KM, Tanguay RL. 2012. MicroRNAs control neurobehavioral development and function in zebrafish. FASEB J 26(4):1452-1461. doi:10.1096/fj.11-194464 PMID:22253472 PMCID:PMC3316906
  • Tilton SC, Tal TL, Scroggins SM, Franzosa JA, Peterson ES, Tanguay RL, Waters KM. 2012. Bioinformatics resource manager v2.3: an integrated software environment for systems biology with microRNA and cross-species analysis tools. BMC Bioinformatics 13(1):311. doi:10.1186/1471-2105-13-311 PMID:23174015 PMCID:PMC3534564

2001

  • Waters KM, Safe SH, Gaido KW. 2001. Differential gene expression in response to methoxychlor and estradiol through ERalpha, ERbeta, and AR in reproductive tissues of female mice. Toxicol Sci 63:47-56. PMID:11509743
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