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Your Environment. Your Health.

OndaVia, Inc.

Superfund Research Program

Fast, Quantitative Analysis of Trichloroethylene in Water

Project Leader: Mark Peterman
Grant Number: R44ES026513
Funding Period: Phase II: September 2018 - August 2020
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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Summary

Groundwater contamination by chlorinated compounds is a significant risk to public health. Chlorine-containing compounds—ranging from pesticides to industrial solvents—are slow to degrade through natural pathways. Their wide-ranging presence is notable. For example, the industrial solvent trichloroethylene (TCE) has been detected at over fourteen-hundred Department of Defense installations, twenty-three Department of Energy installations, and thousands of commercial and residential sites nationwide, including 60 percent of Superfund sites. Although various remediation techniques are under study, all sites would benefit from rapid monitoring.

These compounds are widely present at minute, low-part-per-billion (ppb) concentrations. At the same time, our water sources are threatened by numerous other pollutants with regulatory limits at ppb-levels. Currently available laboratory-based tools that can measure these very low concentrations are expensive, complex, and cumbersome instruments. They do not enable the types of rapid, frequent, economical and broad-based testing needed to adequately monitor the nation's water sources. Next-generation capabilities to test water samples at sub-ppb for a wide-variety of compounds in fewer than five minutes would vastly improve the capabilities of water monitors and researchers. This ability will in turn allow water suppliers to increase monitoring frequency and to implement remediation steps. It will also allow researchers to focus on obtaining more data and a better understanding of the health effects of chronic exposure.

OndaVia is developing the required advanced monitoring technology. As part of this project, OndaVia is developing, prototyping, validating, and plans to commercialize a rapid-analysis instrument designed to measure compounds in aqueous solution using surface- enhanced Raman spectroscopy (SERS). This instrument relies upon OndaVia's proven and proprietary SERS detection technology that is both sensitive and quantitative, resulting in an easy-to- use, rapid-analysis instrument with few-parts-per-billion sensitivity. Specific aims of this project are focused on delivering a prototype TCE analysis kit capable of detecting TCE at 5-ppb in field samples.

Clean water is necessary for a healthy society, yet we are faced with constant new concerns about pollution in our water sources—including ever-increasing threats from trace pollutants such as chlorinated solvents that are widely present in our water supplies. OndaVia aims to develop a rapid, easy-to-use, economical prototype analysis kit that is needed to accurately measure water contamination at ppb-levels to boost our country's ability to monitor and protect our surface, ground, waste, and drinking water sources.

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