Superfund Research Program
- 302 - PAH and Hypoxia Exposure Result in Mitochondrial Dysfunction in Fish -- Di Giulio
Release Date: 02/05/2020
Zebrafish exposed to polycyclic aromatic hydrocarbons (PAHs) in water with inadequate oxygen, or hypoxia, can experience a broad range of effects on the mitochondria, according to an NIEHS Superfund Research Program (SRP)-funded study. Changes to the function and integrity of mitochondria, which are organelles that make energy for the cell, can disrupt metabolism and reduce organism fitness and performance.
- 301 - Cadmium Exposure Impairs Production of Neurons Responsible for Learning and Memory -- Xia
Release Date: 01/08/2020
A new study funded by the Superfund Research Program (SRP) shows cadmium exposure can impair new neurons from forming and maturing in the hippocampus region of the brain. Led by Zhengui Xia, Ph.D., the researchers at the University of Washington (UW) SRP Center also found that cadmium can lead to the death of stem cells that produce these neurons. In people, learning and memory formation depends on the production of new neurons in this region of the brain.