Superfund Research Program
- 321 - First-of-its-Kind Arsenic Meta-Analysis Paves the Way for Future Data Integration -- Cardenas, Gamble
Release Date: 09/01/2021
Researchers from NIEHS Superfund Research Program (SRP) centers at the University of California (UC), Berkeley and Columbia University used advanced analysis techniques to combine data from populations in Chile and Bangladesh. The purpose was to detect common DNA methylation (DNAm) signatures associated with arsenic exposure.
- 320 - Characterizing Arsenic Exposure in Public Water Supplies and Private Wells -- Navas-Acien
Release Date: 08/04/2021
A recent NIEHS Superfund Research Program (SRP)-funded study revealed that while arsenic concentrations in community water systems (CWS) have decreased over time, certain populations are still vulnerable to elevated levels of arsenic.
- 319 - Analyzing Chemicals and Genes Yields Novel Insight into PAH Behavior -- Simonich
Release Date: 07/07/2021
A new NIEHS Superfund Research Program (SRP)-funded study revealed how polycyclic aromatic hydrocarbons (PAHs) breakdown and transform in the presence of ultraviolet A (UVA) light and titanium dioxide nanoparticle pollutants. Their findings have important implications for PAH cleanup, which may not consider how PAHs transform in diverse environments.
- 318 - Combined Approach Sheds Light on Factors Controlling Stream Recovery -- Clements
Release Date: 06/02/2021
Improved water quality and stream ecosystem recovery following treatment of mine waste depends on a mix of physical, chemical, and biological factors, according to a new study funded by the NIEHS Superfund Research Program (SRP) at the Colorado School of Mines. William Clements, Ph.D., professor at Colorado State University, and two doctoral students, led the study.
- 317 - New Technique Sheds Light on PFAS in Coastal Watersheds -- Sunderland
Release Date: 05/05/2021
A new analytical workflow, developed by NIEHS Superfund Research Program (SRP) grantees, can identify and characterize previously undetected per- and polyfluoroalkyl (PFAS) compounds in contaminated watersheds. The team is led by Elsie Sunderland, Ph.D., of the University of Rhode Island SRP Center, and SRP trainee Bridger Ruyle, a doctoral student at Harvard.
- 316 - Arsenic Exposure Before Conception May Trigger Diabetes in Male Offspring -- Fry, Styblo
Release Date: 04/07/2021
Exposure to inorganic arsenic before conception can alter metabolic outcomes in the offspring of mice, with different effects among males and females, according to a new study. Researchers reported, for the first time, a link between changes in gene expression in parents’ reproductive cells and diabetic indicators in offspring.
- 315 - Modeling and Field Tests Yield Promising Results for Aquifer Clean Up -- Christenson, Comfort
Release Date: 03/03/2021
NIEHS Superfund Research Program (SRP) grantees have developed novel, slow-release oxidant-paraffin candles that dissolve and degrade chlorinated contaminants in underground aquifers. The grant recipient, small business AirLift Environmental, worked with partners at the University of Nebraska-Lincoln (UNL) to optimize this groundwater clean-up method and demonstrated its effectiveness in a field study.
- 314 - Triclosan and a High-fat Diet Worsen Liver Disease in Mice -- Tukey
Release Date: 02/03/2021
A new study funded by the NIEHS Superfund Research Program (SRP) shows triclosan exposure, in combination with a high-fat diet, can worsen nonalcoholic fatty liver disease. Led by Robert Tukey, Ph.D., researchers at the University of California San Diego SRP Center described the molecular mechanisms by which triclosan alters metabolism and gut microbiota, resulting in fat buildup in the liver.
- 313 - New Model to Examine PFAS Sheds Light on Lipid Disruption Mechanisms -- Schlezinger, Webster
Release Date: 01/13/2021
Researchers from the Boston University (BU) Superfund Research Program (SRP) Center developed a novel study design that generated new insight on the effects of perfluorooctanoic acid (PFOA) on cholesterol regulation in the liver. Led by Jennifer Schlezinger, Ph.D., the team also investigated the molecular mechanisms of action, focusing on effects of PFOA on the human peroxisome proliferator activated receptor α (hPPARα), a transcription factor that regulates lipid homeostasis.