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University of California-Berkeley: Dataset Details, ID=GSE49677

Superfund Research Program

Toxic Substances in the Environment

Center Director: Martyn T. Smith
Grant Number: P42ES004705
Funding Period: 1987-2027
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Title: Chronic academic stress increases a group of microRNAs in peripheral blood

Accession Number: GSE49677

Link to Dataset:

Repository: Gene Expression Omnibus (GEO)

Data Type(s): Gene Expression

Experiment Type(s): Expression profiling by array

Organism(s): Homo sapiens

Summary: In this study, we examined alterations in microRNA (miRNA) profiles in peripheral blood from male medical students two months and two days before the National Examination for Medical Practitioners. Blood obtained one month after the examination were used as baseline controls. Several miRNAs were significantly elevated during the pre-examination period in association with significant down-regulation of their target mRNAs two days before the examination. Thus, a distinct group of miRNAs in periheral blood may participate in the integrated response to chronic academic stress in healthy young men

Publication(s) associated with this dataset:
  • Daniels SI, Sille FC, Goldbaum A, Yee B, Key EF, Zhang L, Smith MT, Thomas R. 2014. Improving power to detect changes in blood miRNA expression by accounting for sources of variability in experimental designs. Cancer Epidemiol Biomarkers Prev 23(12):2658-2666. doi:10.1158/1055-9965.EPI-14-0623 PMID:25472674 PMCID:PMC4256675
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