Superfund Research Program
TCDD Impedes the Minimal Activation Threshold Required for Initiation of B Cell Differentiation: An Integrated Experimental and Computational Modeling Approach
Project Leader: Norbert E. Kaminski
Grant Number: P42ES004911
Funding Period: 2000-2021
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Datasets
Final Progress Reports
PublicationsTitle: Crystal structure of Lactobacillus helveticus purine deoxyribosyl transferase (PDT) with the tricyclic purine 8,9-dihydro-9-oxoimidazo[2,1-b]purine (N2,3-ethenoguanine)
Accession Number: 4MEJ
Link to Dataset: http://www.rcsb.org/structure/4MEJ
Repository: Protein Data Bank (PDB)
Data Type(s): Protein Structure
Experiment Type(s): X-Ray diffraction
Summary: DOI: 10.2210/pdb4MEJ/pdb Organism(s): Lactobacillus helveticus H10
Publication(s) associated with this dataset:- Ye W, Paul D, Gao L, Seckute J, Sangaiah R, Jayaraj K, Zhang Z, Kaminski P, Ealick SE, Gold A, Ball LM. 2014. Ethenoguanines undergo glycosylation by nucleoside 2'-deoxyribosyltransferases at non-natural sites. PLoS One 9(12):e115082. doi:10.1371/journal.pone.0115082 PMID:25521390 PMCID:PMC4270796