Title: mRNA and miRNA expression analysis of developmental ethanol exposure in zebrafish

Accession Number: GSE30497

Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE30497

Repository: Gene Expression Omnibus (GEO)

Data Type(s): Gene Expression

Experiment Type(s): Expression profiling by array

Organism(s): Danio rerio

Summary: During early neurogenesis, multiple whole animal gene expression profiling studies revealed widespread changes in developmental mRNA and miRNA abundance in ethanol-exposed embryos. Consistent with a role for miRNAs in neurobehavioral development, miRNA target prediction analyses identified multiple miRNAs misexpressed in the ethanol exposed cohorts that were also predicted to target inversely expressed transcripts known to influence brain morphogenesis.

Publication(s) associated with this dataset:

• Tal TL, Franzosa JA, Tilton SC, Philbrick KA, Iwaniec UT, Turner RT, Waters KM, Tanguay RL. 2012. MicroRNAs control neurobehavioral development and function in zebrafish. FASEB J 26(4):1452-1461. doi:10.1096/fj.11-194464 PMID:22253472 PMCID:PMC3316906