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Your Environment. Your Health.

Northeastern University: Dataset Details, ID=GSE96557

Superfund Research Program

Puerto Rico Testsite for Exploring Contamination Threats (PROTECT)

Center Director: Akram N. Alshawabkeh
Grant Number: P42ES017198
Funding Period: 2010-2025
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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Title: Expression data from fetal membranes

Accession Number: GSE96557

Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE96557

Repository: Gene Expression Omnibus (GEO)

Data Type(s): Gene Expression

Experiment Type(s): Expression profiling by array

Organism(s): Homo sapiens

Summary: Genome wide expression profiling was used to identify signifnificantly changed genes in fetal membranes after GBS treatment. Genome-wide expression profiles in GBS-inoculated human extraplacental membranes in vitro were used to identify transcriptomic pathways altered by GBS . Using bioinformatics analysis of these expression profiles we aimed to test our hypothesis that GBS activates pathways related to inflammation and premature birth in human extraplacental membranes.

Publication(s) associated with this dataset:
  • Park H, Harris SM, Boldenow E, McEachin RC, Sartor MA, Chames MC, Loch-Caruso R. 2017. Group B streptococcus activates transcriptomic pathways related to premature birth in human extraplacental membranes in vitro. Biol Reprod 98(3):396-407. doi:10.1093/biolre/iox147 PMID:29155939 PMCID:PMC6248496
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