Superfund Research Program

Michael C. Petriello

Wayne State University
Lexington, Kentucky
Email: michael.petriello@wayne.edu

Projects

• Wayne State University: Impact of BTEX Chemical Exposure During Pregnancy to Maternal and Fetal Well-Being (2022-2027)
• Wayne State University: Research Experience & Training Coordination Core (2022-2027)

Publications

2023

• Agarwal M, Hoffman JB, Tenlep SY, Santarossa S, Pearson KJ, Sitarik AR, Cassidy-Bushrow AE, Petriello MC. 2023. Maternal polychlorinated biphenyl 126 (PCB 126) exposure modulates offspring gut microbiota irrespective of diet and exercise. Reprod Toxicol 118:108384. doi:10.1016/j.reprotox.2023.108384 PMID:37061048 PMCID:PMC10257154
• Maxwell A, Adzibolosu N, Hu A, You Y, Stemmer PM, Ruden D, Petriello MC, Sadagurski M, Debarba L, Koshko L, Ramadoss J, Nguyen AT, Richards D, Liao A, Mor GG, Ding J. 2023. Intrinsic sexual dimorphism in the placenta determines the differential response to benzene exposure. iScience 26(4):106287. doi:10.1016/j.isci.2023.106287 PMID:37153445 PMCID:PMC1015661

2022

• Petriello MC, Mottaleb MA, Serio TC, Balyan B, Cave MC, Birnbaum LS, Morris AJ. 2022. Serum concentrations of legacy and emerging per- and polyfluoroalkyl substances in the Anniston Community Health Surveys (ACHS I and ACHS II). Environ Int 158:106907. doi:10.1016/j.envint.2021.106907 PMID:34763231

2020

• Deng P, Hoffman JB, Petriello MC, Wang C, Li X, Kraemer MP, Morris AJ, Hennig B. 2020. Dietary inulin decreases circulating ceramides by suppressing neutral sphingomyelinase expression and activity in mice. J Lipid Res 61:45-53. doi:10.1194/jlr.RA119000346 PMID:31604806 PMCID:PMC6939596
• Hoffman JB, Petriello MC, Morris AJ, Mottaleb MA, Sui Y, Zhou C, Deng P, Wang C, Hennig B. 2020. Prebiotic inulin consumption reduces dioxin-like PCB 126-mediated hepatotoxicity and gut dysbiosis in hyperlipidemic Ldlr deficient mice. Environ Pollut 261:114183. doi:10.1016/j.envpol.2020.114183 PMID:32105967 PMCID:PMC7220843
• Mottaleb MA, Petriello MC, Morris AJ. 2020. High-throughput UHPLC-MS/MS measurement of per- and poly-fluorinated alkyl substances in human serum. J Anal Toxicol 44(4):339-347. doi:10.1093/jat/bkz097 PMID:31776573 PMCID:PMC7299301

2019

• Deng P, Barney J, Petriello MC, Morris AJ, Wahlang B, Hennig B. 2019. Hepatic metabolomics reveals that liver injury increases PCB 126-induced oxidative stress and metabolic dysfunction. Chemosphere 217:140-149. doi:10.1016/j.chemosphere.2018.10.196 PMID:30415113 PMCID:PMC6626632
• Deng P, Li X, Petriello MC, Wang C, Morris AJ, Hennig B. 2019. Application of metabolomics to characterize environmental pollutant toxicity and disease risks. Rev Environ Health 34(3):251-259. doi:10.1515/reveh-2019-0030 PMID:31408434 PMCID:PMC6915040
• Hennig B, Petriello MC. 2019. Nutritional modulation of environmental toxicity and implications in inflammatory diseases. Toxicol Lett 314:S88. doi:10.1016/j.toxlet.2019.09.002
• Wang C, Petriello MC, Zhu B, Hennig B. 2019. PCB 126 induces monocyte/macrophage polarization and inflammation through AhR and NF-kB pathways. Toxicol Appl Pharmacol 367:71-81. doi:10.1016/j.taap.2019.02.006 PMID:30768972 PMCID:PMC6402591

2018

• Hennig B, Petriello MC, Gamble MV, Surh Y, Kresty LA, Frank N, Rangkadilok N, Ruchirawat K, Suk WA. 2018. The role of nutrition in influencing mechanisms involved in environmentally mediated diseases. Rev Environ Health 33:87-97. doi:10.1515/reveh-2017-0038 PMID:29381475 PMCID:PMC5987536
• Petriello MC, Brandon JA, Hoffman JB, Wang C, Tripathi H, Abdel-Latif A, Ye X, Li X, Yang L, Lee EY, Soman S, Barney J, Wahlang B, Hennig B, Morris AJ. 2018. Dioxin-like PCB 126 increases systemic inflammation and accelerates atherosclerosis in lean LDL receptor-deficient mice. Toxicol Sci 162(2):548-558. doi:10.1093/toxsci/kfx275 PMID:29216392 PMCID:PMC5888982
• Petriello MC, Charnigo RJ, Sunkara M, Soman S, Pavuk M, Birnbaum LS, Morris AJ, Hennig B. 2018. Relationship between serum trimethylamine N-oxide and exposure to dioxin-like pollutants. Environ Res 162:211-218. doi:10.1016/j.envres.2018.01.007 PMID:29353125 PMCID:PMC5811317
• Petriello MC, Hoffman JB, Vsevolozhskaya O, Morris AJ, Hennig B. 2018. Dioxin-like PCB 126 increases intestinal inflammation and disrupts gut microbiota and metabolic homeostasis. Environ Pollut 242(A):1022-1032. doi:10.1016/j.envpol.2018.07.039 PMID:30373033 PMCID:PMC6211811

2017

• Hennig B, Petriello MC, Newsome B, Perkins JT, Liu D. 2017. Antioxidant therapy against persistent organic pollutants and associated diseases. Chapter 9 in: Nutritional Antioxidant Therapies: Treatments and Perspectives. Springer International Publishing, pp.217-246.
• Hoffman JB, Petriello MC, Hennig B. 2017. Impact of nutrition on pollutant toxicity: an update with new insights into epigenetic regulation. Rev Environ Health 32(1-2):65-72. doi:10.1515/reveh-2016-0041 PMID:28076319 PMCID:PMC5489226
• Perkins JT, Petriello MC, Xu L, Stromberg AJ, Hennig B. 2017. An open sourced statistical application for identifying complex toxicological interactions of environmental pollutants. Rev Environ Health 32(1-2):23-26. doi:10.1515/reveh-2016-0044 PMID:28118146 PMCID:PMC5489228
• Petriello MC, Hoffman JB, Morris AJ, Hennig B. 2017. Emerging roles of xenobiotic detoxification enzymes in metabolic diseases. Rev Environ Health 32(1-2):105-110. doi:10.1515/reveh-2016-0050 PMID:27837601 PMCID:PMC5604474
• Wahlang B, Barney J, Thompson B, Wang C, Hamad OM, Hoffman JB, Petriello MC, Morris AJ, Hennig B. 2017. Editors highlight: PCB126 exposure increases risk for peripheral vascular diseases in a liver injury mouse model. Toxicol Sci 160:256-267. doi:10.1093/toxsci/kfx180 PMID:28973532 PMCID:PMC5837513
• Wahlang B, Perkins JT, Petriello MC, Hoffman JB, Stromberg AJ, Hennig B. 2017. A compromised liver alters polychlorinated biphenyl-mediated toxicity. Toxicology 380:11-22. doi:10.1016/j.tox.2017.02.001 PMID:28163111 PMCID:PMC5374277

2016

• Murphy MO, Petriello MC, Han S, Sunkara M, Morris AJ, Esser K, Hennig B. 2016. Exercise protects against PCB-induced inflammation and associated cardiovascular risk factors. Environ Sci Pollut Res Int 23(3):2201-2211. doi:10.1007/s11356-014-4062-6 PMID:25586614 PMCID:PMC4503535
• Perkins JT, Petriello MC, Newsome B, Hennig B. 2016. Polychlorinated biphenyls and links to cardiovascular disease. Environ Sci Pollut Res Int 23(3):2160-2172. doi:10.1007/s11356-015-4479-6 PMID:25877901 PMCID:PMC4609220
• Petriello MC, Hoffman JB, Sunkara M, Wahlang B, Perkins JT, Morris AJ, Hennig B. 2016. Dioxin-like pollutants increase hepatic flavin containing monooxygenase (FMO3) expression to promote synthesis of the pro-atherogenic nutrient biomarker trimethylamine N-oxide from dietary precursors. J Nutr Biochem 33:145-153. doi:10.1016/j.jnutbio.2016.03.016 PMID:27155921 PMCID:PMC4893916
• Wahlang B, Petriello MC, Perkins JT, Shen S, Hennig B. 2016. Polychlorinated biphenyl exposure alters the expression profile of microRNAs associated with vascular diseases. Toxicol In Vitro 35:180-187. doi:10.1016/j.tiv.2016.06.001 PMID:27288564 PMCID:PMC4949395

2015

• Liu D, Perkins JT, Petriello MC, Hennig B. 2015. Exposure to coplanar PCBs induces endothelial cell inflammation through epigenetic regulation of NF-κB subunit p65. Toxicol Appl Pharmacol 289(3):457-465. doi:10.1016/j.taap.2015.10.015 PMID:26519613 PMCID:PMC4662647

2014

• Newsome B, Petriello MC, Han S, Murphy MO, Eske KE, Sunkara M, Morris AJ, Hennig B. 2014. Green tea diet decreases PCB 126-induced oxidative stress in mice by up-regulating antioxidant enzymes. J Nutr Biochem 25(2):126-135. doi:10.1016/j.jnutbio.2013.10.003 PMID:24378064 PMCID:PMC3946959
• Petriello MC, Han S, Newsome B, Hennig B. 2014. PCB 126 toxicity is modulated by cross-talk between caveolae and Nrf2 signaling. Toxicol Appl Pharmacol 277(2):192-199. doi:10.1016/j.taap.2014.03.018 PMID:24709675 PMCID:PMC4041015
• Petriello MC, Newsome B, Dziubla TD, Hilt JZ, Bhattacharyya D, Hennig B. 2014. Modulation of persistent organic pollutant toxicity through nutritional intervention: emerging opportunities in biomedicine and environmental remediation. Sci Total Environ 491-492:11-16. doi:10.1016/j.scitotenv.2014.01.109 PMID:24530186 PMCID:PMC4077968
• Petriello MC, Newsome B, Hennig B. 2014. Influence of nutrition in PCB-induced vascular inflammation. Environ Sci Pollut Res Int 21(10):6410-6418. doi:10.1007/s11356-013-1549-5 PMID:23417440 PMCID:PMC3686851